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小胶园的刺激割胶措施

福建热作科技 1982年第3期 63-64页

作者： P.D.Abrahm ,j.L.anthony ,郑达曾

马来西亚小胶园占胶树总面积2/3以上,为了改善小胶园主的经济地位,最近正在进行用高产栽培品种更新无经济价值胶园的工作.然而大约30%的小胶园是低产树或老龄树,这些胶园采用适当的刈胶和刺激方法能获得有经济效益的产量.乙烯丰刺激剂... 详细信息

马来西亚小胶园占胶树总面积2/3以上,为了改善小胶园主的经济地位,最近正在进行用高产栽培品种更新无经济价值胶园的工作.然而大约30%的小胶园是低产树或老龄树,这些胶园采用适当的刈胶和刺激方法能获得有经济效益的产量.乙烯丰刺激剂使用于小胶园的做法,必须适合目前流行的刈胶栽培措施.另外,小胶园是天然混杂的.因此一系列的试验计划已在马来西亚有代表性的小胶园中进行.这些试验的目的是评定橡胶树刺激后的表现以及观察乙烯丰长期刺激的效应.为了便于调查,一

关键词：胶园经济马来西亚产量长流胶刺激剂

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对外贸易与国内地理布局

经济资料译丛 2007年第4期 21-33页

作者： Masahisa Fuj.ta Paul Krugman anthony j.Venables 徐海玲（译）不详东北师范大学经济学院 130117

在这本书（指《空间经济：城市、区域和国际贸易》一书）中，我们将建立三种模型：一是区域模型，在此模型中工业制成品是可流动的而农产品是不可流动的：二是城市模型，在此模型中除了土地以外，其它要素都是可流动的；三是国际模型，... 详细信息

在这本书（指《空间经济：城市、区域和国际贸易》一书）中，我们将建立三种模型：一是区域模型，在此模型中工业制成品是可流动的而农产品是不可流动的：二是城市模型，在此模型中除了土地以外，其它要素都是可流动的；三是国际模型，在此模型中要素不可流动，

关键词：对外贸易城市模型地理国内国际贸易工业制成品空间经济农产品

Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation

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Bone Research 2022年第4期10卷 826-837页

作者： Yugo Morita Motoo Saito j.vier Rangel-Moreno anthony M.Franchini j.hn R.Owen j.hn C.Martinez j.hn L.Daiss Karen L.de Mesy Bentley Stephen L.Kates Edward M.Schwarz Gowrishankar Muthukrishnan Center for Musculoskeletal Research University of Rochester Medical CenterRochesterNYUSA Division of Allergy Immunology and RheumatologyDepartment of MedicineUniversity of Rochester Medical CenterRochesterNYUSA Department of Environmental Medicine University of Rochester School of Medicine and DentistryRochesterNYUSA Department of Orthopedic Surgery Virginia Commonwealth UniversityRichmondVAUSA Department of Orthopedics University of Rochester Medical CenterRochesterNYUSA Department of Pathology and Laboratory Medicine University of Rochester Medical CenterRochesterNYUSA

Interleukin-27 is a pleiotropic cytokine whose functions during bacterial infections remain controversial,and its role in patients with *** osteomyelitis is *** address this knowledge gap,we completed a clinical study and observed elevated serum IL-27 levels(20-fold higher,Pj.ction of rAAV-IL-27p28 or rAAV-GFP,*** found that IL-27 was induced at the surgical site within 1 day of *** infection of bone and was expressed by M0,M1 and M2 macrophages and osteoblasts but not by ***,exogenous IL-27p28(~2 ng·mL^(−1) in serum)delivery ameliorated soft tissue abscesses and periimplant bone loss during infection,accompanied by enhanced local IL-27 expression,significant accumulation of RORγt^(+)neutrophils at the infection site,a decrease in RANK^(+) cells,and compromised osteoclast *** effects were not observed in IL-27Rα^(−/−)mice compared with WT mice,suggesting that IL-27 is dispensable for immunity but mediates redundant immune and bone cell functions during *** vitro studies and bulk RNA-seq of infected tibiae showed that IL-27 increased nos1,nos2,il17α,il17f,and rorc expression but did not directly stimulate ***,these results identify a novel phenomenon of IL-27 expression by osteoblasts immediately following *** infection of bone and suggest a protective role of systemic IL-27 in osteomyelitis.

关键词： abscess protective immunity

Utilization of Extracorporeal Membrane Oxygenation for Pulmonary Toxicity Caused by Inhaled Synthetic Cannabinoid. A Harbinger of Future Complications Associated with Inhaled Cannabinoid Products

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International j.urnal of Clinical Medicine 2020年第2期11卷 53-61页

作者： Robert March Paul Guentert Elizabeth Kloska-Kearney David Kwak Cody Yerger Michael McBride j. R. Maj.wski Ross McCauley j.rdan Hatch j.cob Speybroeck Allen Betts Mat Marsee Sufyan Zackariya Faisal Shariff Shivani Patel Ali Sualeh anthony Thomas Edward Evans Donald Westerhausen Mark Walsh Saint j.seph Regional Medical Center Mishawaka IN USA Indiana University School of Medicine—South Bend South Bend IN USA Department of Pulmonary and Critical Care Medicine Methodist Hospital Indianapolis IN USA

There has been a dramatic increase in medical complications related to synthetic cannabinoid (SC) use either by water pipe or vaping. The legalization of marij.ana in an increasing number of states has also resulted in an increase in a number of complications related not j.st to marij.ana, but in particular, to SC. As a result, there have been recent increased reports of acute pulmonary inj.ry related to inhaled SC products. We describe that rarely endotracheal intubation with mechanical ventilation has been required to treat the acute respiratory distress syndrome (ARDS) and the diffuse alveolar hemorrhage (DAH) associated with the acute toxicity of SC inhalation. We describe the second reported case of successful utilization of mechanical ventilation and extracorporeal membrane oxygenation (ECMO) in order to treat acute pulmonary toxicity caused by SC inhalation by a water pipe. While the exact pathophysiology of these interesting and recent pulmonary complications is unknown, the recent increase in exposure to SC via water pipe systems and vaping suggests that there will be many more cases of patients that will require ECMO as a form of life-saving therapy.

关键词： Synthetic Cannabinoid Extracorporeal Membrane Oxygenation Mechanical Ventilation Water Pipe Vaping Pulmonary Toxicity

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空气污染控制设备指南

Beyond the synucleinopathies:alpha synuclein as a driving force in neurodegenerative comorbidities

1992年

作者：（美）西奥多（Theodore Louis）（美）布尼科尔（Buonicore anthony.j.）黄定生译

书名原文∶Air pollution control equipment:selection design,operation and maintenance:本书介绍了工业中常用各种空气污染控制设备的结构、性能及应用场合,包括吸收塔、吸附器、焚烧炉、冷凝器、机械集尘装置、袋滤器、湿式洗涤器... 详细信息

ISBN: (纸本)7800432270

书名原文∶Air pollution control equipment:selection design,operation and maintenance:本书介绍了工业中常用各种空气污染控制设备的结构、性能及应用场合,包括吸收塔、吸附器、焚烧炉、冷凝器、机械集尘装置、袋滤器、湿式洗涤器、静电除尘设备、烟道气脱硫系统以及烟囱等。

关键词：空气污染控制学科:设备

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Translational Neurodegeneration 2019年第1期8卷 346-358页

作者： Naomi P.Visanj. anthony E.Lang Gabor G.Kovacs Edmond j.Safra program in Parkinson’s disease and the Morton and Gloria Shulman Movement disorders clinic Toronto Western HospitalTorontoOntarioCanada Department of Laboratory Medicine and Pathobiology and Tanz Centre for Research in Neurodegenerative Disease University of TorontoTorontoOntarioCanada Laboratory Medicine Program&Krembil Brain Institute University Health NetworkTorontoOntarioCanada

The fundamental role that alpha-synuclein(aSyn)plays in the pathogenesis of neurodegenerative synucleinopathies,including Parkinson’s disease,dementia with Lewy bodies,and multiple system atrophy,is a well-accepted fact.A wealth of experimental evidence has linked this relatively small but ubiquitously expressed protein to a plethora of cytopathologic mechanisms and suggests that aSyn may be capable of seeding the progressive spread of synucleinopathy throughout the *** the synucleinopathies,the abnormal deposition of aSyn is frequently seen in a variety of other neurodegenerative proteinopathies including Alzheimer’s *** spite of the fact that the frequency of concomitant aSyn pathology in these disorders is such that it can be considered the rule rather than the exception,the potential role that aSyn may have in these disorders has received relatively little *** this article we postulate that aSyn may in fact be a key protein in driving the pathogenic processes in neurodegenerative *** addition to reviewing the frequency of concomitant deposition of aSyn in the neurodegenerative proteinopathies,we also consider our current understanding of the interaction of aSyn with other neurodegenerative disease-associated proteins,including tau,TDP-43,amyloid-βand prion protein,in the context of neuropathologic studies describing the anatomical sites of potential concomitant *** conclude that a growing body of evidence,encompassing neuropathology studies in human brain,animal models of concomitant proteinopathies and studies employing sophisticated methods of probing protein-protein interaction,cumulatively suggest that aSyn is well positioned to exert a strong influence on the pathogenesis of the neurodegenerative *** hope to stimulate research in this emerging field and consider that future studies exploring the contribution of aSyn to the pathogenic processes in neurodegenerative comorbidities may provide critical

关键词： Amyloid-β Alpha-synuclein Alzheimer’s disease Comorbidity Dementia with Lewy bodies Multiple system atrophy Neurodegeneration Parkinson’s disease Prion protein Progressive supranuclear palsy Proteinopathy Tau TDP-43

Sci Rep:科学家阐明线粒体的程序性细胞死亡过程

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现代生物医学进展 2016年第35期16卷 I0004-I0004页

作者： Ted D. Pham Phi Q. Pham j.nfeng Li anthony G. Letai Douglas C. Wallace Peter j. Burke Department of Biomedical Engineering University of California Irvine CA USA Department of Chemical Engineering and Materials Science University of California Irvine CA USA Department of Chemical Engineering and Materials Science University of California Irvine CA USA Dana-Farber Cancer Institute Harvard University Boston MA USA Center for Mitochondrial and Epigenomic Medicine Children’s Hospital of Philadelphia and Department of Pathology and Laboratory Medicine University of Pennsylvania Philadelphia PA USA Department of Biomedical Engineering University of California Irvine CA USA Department of Chemical Engineering and Materials Science University of California Irvine CA USA Department of Electrical Engineering and Computer Science University of California Irvine CA USA

日前。发表在Scientific Reports杂志上的一篇研究报告中，来自加利福尼亚大学等机构的研究人员通过利用一种由石墨烯组成的新型传感器深入解析了线粒体的程序性细胞死亡过程，该研究或为驱动癌细胞自我毁灭提供了新的线索。研究者通过... 详细信息

日前。发表在Scientific Reports杂志上的一篇研究报告中，来自加利福尼亚大学等机构的研究人员通过利用一种由石墨烯组成的新型传感器深入解析了线粒体的程序性细胞死亡过程，该研究或为驱动癌细胞自我毁灭提供了新的线索。研究者通过研究开发了一种监测线粒体改变的电子学方法，该方法能够指示出细胞进行自我毁灭的开始阶段，我们机体每个细胞中都有数百个、甚至数千个线粒体。每个线粒体都有着内膜和外膜结构；作为细胞的能量工厂，线粒体会对细胞中的碳水化合物和脂肪进行代谢产能以便细胞利用并且储存。但同时线粒体还有第二个角色，那就是调节细胞的生死通路。

关键词：死亡过程癌细胞线粒体程序性 Sci 科学家 Rep 加利福尼亚大学

人HCN4通道的滞后现象:影响窦房结起搏的潜在决定因素(英文)

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生理学报 2010年第1期62卷 1-13页

作者：萧永福 Natalie Chandler Halina Dobrzynski Eric S.Richardson Erica M.TenBroek j.shua j.Wilhelm Vinod Sharma anthony Varghese Mark R.Boyett Paul A.Iaizzo Daniel C.Sigg 美敦力公司心脏节律疾病管理部曼彻斯特大学医学院明尼苏达州大学外科学系明尼苏达州大学整合生物学与生理学系美敦力公司科学技术部威斯康辛大学雷河分校计算机系

超极化活化环核苷酸门控(hyperpolarization-activated cyclic-nucleotide-gated,HCN)通道参与调制心脏跳动的节律和速率。与HCN1和HCN2有所不同,慢通道HCN4可能不存在电压依赖的滞后现象。本研究采用单细胞膜片钳方法,在稳定转染hHCN4... 详细信息

超极化活化环核苷酸门控(hyperpolarization-activated cyclic-nucleotide-gated,HCN)通道参与调制心脏跳动的节律和速率。与HCN1和HCN2有所不同,慢通道HCN4可能不存在电压依赖的滞后现象。本研究采用单细胞膜片钳方法,在稳定转染hHCN4的HEK293细胞上进行电生理记录,观察hHCN4通道是否存在滞后现象,以及cAMP对其的调制作用;同时采用实时定量RT-PCR方法检测窦房结和心房组织中HCNs的表达。电压钳实验结果显示hHCN4电流(Ih)激活随着保持电位超极化的变化而向去极化方向移动。三角电位变化钳(triangular ramp)和动作电位钳的结果也显示了hHCN4的滞后现象。cAMP增加Ih电流幅度,且使电流激活向去极化方向移动,从而改变内源性hHCN4滞后行为。RT-PCR结果显示,人窦房结组织主要表达HCN4,占75%,HCN1占21%,HCN2占3%,HCN3占0.7%。以上结果提示,人窦房结组织主要表达HCN4亚型,hHCN4的Ih存在电压依赖性的滞后现象,且受cAMP调制。由此推断,hHCN4通道的滞后现象可能在窦房结起搏活动中起到了关键作用。

关键词： HCN4通道滞后窦房结 cAMP

Portable ultrasonography in mass casualty incidents:The CAVEAT examination

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World j.urnal of Orthopedics 2010年第1期1卷 10-19页

作者： Stanislaw Peter Stawicki j.mes M Howard j.hn P Pryor David P Bahner Melissa L Whitmill anthony j.Dean Department of Surgery Division of Critical CareTraumaand BurnThe Ohio State University Medical CenterColumbusOH 43210United States Department of Surgery Division of Traumatology and Surgical Critical CareUniversity of Pennsylvania School of MedicinePhiladelphiaPA 19104United States Department of Emergency Medicine The Ohio State University Medical CenterColumbusOH 43210United States Department of Emergency Medicine University of Pennsylvania School of MedicinePhiladelphiaPA 19104United States

Ultrasonography used by practicing clinicians has been shown to be of utility in the evaluation of time-sensitive and critical illnesses in a range of environments,including pre-hospital triage,emergency department,and critical care *** increasing availability of lightweight,robust,user-friendly,and low-cost portable ultrasound equipment is particularly suited for use in the physically and temporally challenging environment of a multiple casualty incident(MCI).Currently established ultrasound applications used to identify potentially lethal thoracic or abdominal conditions offer a base upon which rapid,focused protocols using hand-carried emergency ultrasonography could be *** a detailed review of the current use of portable ultrasonography in military and civilian MCI settings,we propose a protocol for sonographic evaluation of the chest,abdomen,vena cava,and extremities for acute *** protocol is two-tiered,based on the urgency and technical difficulty of the sonographic *** addition to utilization of well-established bedside abdominal and thoracic sonography applications,this protocol incorporates extremity assessment for long-bone *** of the proposed protocol will need to be conducted to determine its utility in simulated and actual MCI settings.

关键词： Focused Assessment with Sonography in Trauma Chest,abdomen,vena cava,and extremities for acute triage Ultrasonography Disaster Field triage Pre-hospital care Mass casualty incident