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Ependymal cells and multiple sclerosis: proposing a relationship

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Neural Regeneration Research 2020年第2期15卷 263-264页

作者： Dale Hatrock Nina Caporicci-nucci Jo anne Stratton The Montreal Neurological Institute McGill UniversityMontrealCanada Integrated Program in Neuroscience McGill UniversityMontrealCanada

Multiple sclerosis (MS) currently affects ~2.5 million people worldwide. MS is typically diagnosed in young adults and is usually not fatal, meaning people live long lives with MS. Affected individuals usually suffer from progressive physical and/or cognitive disability, often including fatigue (89.6%), depression (53.9%), memory loss (49.0%), motor or sensory dysfunction (76.4%, 70.4%) and urinary incontinence (50.8%).

关键词： multiple sclerosis relationship dysfunction

Preliminary studies on occurrence of monensin antibiotic in Bosque River Watershed

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Journal of Environmental Sciences 2013年第2期25卷 268-273页

作者： Sudarshan Kurwadkar Victoria Sicking Barry Lambert anne McFarland Forrest Mitchell Environmental Engineering Department of Engineering and PhysicsBox T-0390Tarleton State UniversityStephenvilleTX 76402USA Environmental Engineering Program Department of Engineering and PhysicsTarleton State UniversityStephenvilleTX 76402USA Department of Animal Sciences Box T-0070Tarleton State UniversityStephenvilleTX 76402USA Texas Institute for Applied Environmental Research Box T-0410Tarleton State UniversityStephenvilleTX 76402USA Texas A&M AgriLife Research 1229 N.US Hwy 281StephenvilleTX 76401USA

Water quality impact due to excessive nutrients has been extensively studied. In recent years, however, micro-pollutants such as pharmaceuticals and hormonal products used in animal agriculture have added an additional impact to overall water quality. Pharmaceuticals used in the poultry, swine, beef, and dairy industries have been detected in various environmental matrices such as, soil, groundwater and surface water. In this study, 26 surface water samples were collected throughout the Bosque River Watershed （BRW） with samples representing a range of land use conditions and locations of major dairy operations. Samples were analyzed using commercially available Enzyme-Linked Immunosorbent Assay test. Of the 26 samples, three samples consistently tested positive for monensin antibiotic with concentration ranging from 0.30 to 3.41 μg/L. These three samples were collected from sites that received varying amount of agriculture wastes （11.7% to 31.3%） and located downstream from sites associated with moderate levels of animal agriculture. The preliminary results suggest that there is a potential for monensin occurrence in the BRW, although initial findings indicate only very low levels.

关键词： ELISA ionophore monensin antibiotic dairy waste emerging pollutants pharmaceuticals

Forget-me-not： Complex floral displays, inter-signal interactions, and pollinator cognition

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Current Zoology 2011年第2期57卷 215-224页

作者： anne S. LEONARD Anna DORNHAUS Daniel R. PAPAJ Center for Insect Science / Department of Ecology and Evolutionary Biology University of Arizona Tucson AZ 85721 USA

Flowers are multisensory displays used by plants to influence the behavior of pollinators. Although we know a great deal about how individual signal components are produced by plants and detected or learned by pollinators, very few experiments directly address the function of floral signal complexity, i.e. how the multicomponent nature of these signals benefits plant or pollinator. Yet, experimental psychology suggests that increasing complexity can enhance subjects＇ ability to detect, learn and remember stimuli, and the plant＇s reproductive success depends upon ensuring that pollinators learn their signals and so transport pollen to other similar （conspecific） flowers. Here we explore functional hypotheses for why plants invest in complex floral displays, focusing on hypotheses in which floral signals interact to promote pollinator learning and memory. Specifically, we discuss how an attention-altering or context-providing function of one signal may promote acquisition or recall of a second signal. Although we focus on communication between plants and pollinators, these process-based hypotheses should apply to any situation where a sender benefits from enhancing a receiver＇s acquisition or recall of information .

关键词： Multimodal signal Learning Attention Bee Context Flower

Impact of male condition on his spermatophore and consequences for female reproductive performance in the Glanville fritillary butterfly

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Insect Science 2018年第2期25卷 284-296页

作者： anne Duplouy Luisa Woestmann Juan Gallego Zamorano Marjo Saastamoinen Metapopulation Research Centre Department of Biosciences University of Helsinki Helsinki Finland Czech University of Life Science Faculty of Environmental Sciences Department of Ecology Prague Czech Repubfi

In butterflies, male reproductive success is highly related to the quality and the size of the spermatophore transferred to the female. The spermatophore is a capsule produced by the male during copulation, which in many species contains sperm in addition to a nuptial gift, and which is digested by the female after copulation. The nuptial gift may contribute to egg production and offspring quality, and in some cases also to female body maintenance. The production of the spermatophore, however, represents a cost for the male and, in polyandrous species, ejaculates are sometimes allocated adaptively across matings. Nonetheless, although the ecological factors affecting the reproductive success of female butterflies have been the topic of numerous studies, little information exists on the factors affecting males＇ contribution to reproduction, and the indirect impacts on female fecundity and fitness. We used the Glanville fritillary butterfly, Melitaea cinxia （Linnaeus, 1758）（Nymphalidae）, in order to assess variation in male allocation to matings. In this species, smaller males produce smaller spermatophores, but variation in spermatophore size is not correlated with female reproductive success. We show that spermatophore size increases with male age at first mating, decreases with mating frequency and adult food-deprivation, and is not influenced by developmental food-limitation. The length of copulation period does not influence the spermatophore size nor influences the polyandrous mating behavior in this species. Male contribution to his spermatophore size is clearly influenced by his condition and adult-resource at the time of mating. Despite this variation, spermatophore size does not seem to have a direct impact on female reproductive output or mating behavior.

关键词： ejaculate fecundity food-restriction Melitaea cinxia

Marine Oxygen Isotope Stage(MIS)-6 Glacial Advances on the Tibetan Plateau More Extensive than during MIS-2 due to More Abundant Precipitation

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Acta Geologica Sinica(English Edition) 2022年第5期96卷 1484-1494页

作者： Marie-Luce CHEVALIER WANG Shiguang anne REPLUMAZ LI Haibing Key Laboratory of Deep-Earth Dynamics of Ministry of Natural Resources Institute of GeologyCAGSBeijing 100037China Jiangsu Donghai Crustal Activity in Deep Holes of the Continental Scientific Drilling National Observation and Research Station LianyungangJiangsu 222300China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China National Institute of Natural Hazards MEMCBeijing 100037China ISTerre UniversitéGrenoble AlpesCNRSGrenoble 38610France

Numerous studies dated glacial deposits within the Himalayan-Tibetan *** most focus on young deposits,i.e.,younger than the Last Glacial Maximum(LGM or Marine oxygen Isotope Stage(MIS)-2,~20 ka),older moraines such as those from MIS-6(~130–191 ka)are much harder to date and interpret due to the less well-preserved nature of their surfaces and boulders,as well as their scattered and continuous age distribution due to long-lived erosion since ***,we dated with~(10)Be,two imbricated moraines near Yadong in southern Tibet,as MIS-2 and 6,showing that the most extensive,smooth surfaces were abandoned during *** published data from 54 MIS-6 moraines on the Tibetan Plateau reveals that they exist in most regions,dry or *** are particularly well-preserved(sharp crests)in eastern and northern Tibet,while in southern and central Tibet,their crests are rounded to *** both MIS-2 and 6 were equally cold,and because MIS-6 moraines are much more extensive than those from the LGM,we conclude that MIS-6 glacial advances were controlled by more abundant precipitation than during *** would be consistent with the peak in Asian monsoon during MIS-6,revealed by sediments from the South China Sea.

关键词： Yadong rift southern Tibet cosmogenic isotopes Quaternary paleo-precipitation moraine morphology Indian monsoon

Representation of Specific Diagnosis for Low Back Pain Using the 11^(th) Revision of International Classification of Diseases and Related Health Problems: Perspectives of Conventional Medicine and Traditional Medicine

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World Journal of Traditional Chinese Medicine 2021年第2期7卷 234-239页

作者： anne Chang Hong Zhao UF Central Administration Medical History and Culture HeritageKarolinska InstituteSolnaSweden Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijingChina

Background:The 11th revision of the International Classification of Diseases and Related Health Problems(ICD-11)was released on June 18,2018,by the World Health Organization and will come into effect on January 1,*** from the chapters on the classification of diseases in the conventional medicine(CM),a new chapter,traditional medicine(TM)conditions–Module 1,was *** back pain(LBP)is one of the common reasons for the physician *** classification codes for LBP in the ICD-11 are vital to documenting accurate clinical ***:The qualitative case study method was *** secondary use data for 100 patients were randomly selected using the ICD-11 online interface to find the classification codes for both the CM section and the TM Conditions–Module 1(TM1)section for LBP ***:Of the 27 codes obtained from the CM section,six codes were not relevant to LBP,whereas the other 21 codes represented diagnoses of LBP and its related diseases or *** the TM1 section,six codes for different patterns and disorders represented the diagnoses for LBP from the TM ***:This study indicates that specific diagnoses of LBP can be represented by the combination of CM classification codes and TM1 classification codes in the ICD-11;the CM codes represent specific and accurate clinical diagnoses for LBP,whereas the TM1 codes add more accuracy to the diagnoses of different patterns from the TM perspective.

关键词： 11^(th)revision of the International Classification of Diseases and Related Health Problems revision low back pain traditional medicine conditions-module 1

Implementation of an in-house flow cytometric analysis of DNA fragmentation in spermatozoa

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Asian Journal of Andrology 2020年第3期22卷 246-251页

作者： anne Sofie Rex Chunsen Wu Jorn Aagaard Jens Fedder Centre of Andrology and Fertility Clinic Odense University HospitalOdense 5000Denmark Aagaard Gynaecological Clinic Skejby 8200AarhusDenmark Research Unit of Gynaecology and Obstetrics Faculty of HealthUniversity of Southern DenmarkOdense 5000Denmark.

An increased amount of DNA fragme ntation in the spermatozoa(SDF)is linked to male in *** Sperm Chromati n Structure Assay(SCSA)is widely used for analysis of ***,the current software(SCSASoftR)linked to this assay is licensed and often located within larger diagnostic *** this study,we present a protocol for using other types of software than SCSASoftR to determine the SDF index(DFI)with clinical *** protocol is engineered after collect!ng and analyzing 254 samples from fertility patients and sperm donors over a 15-month *** is analyzed using a strict protocol where the spermatozoa are treated with a strong acid(pH 1.2)followed by acridine *** is determined by a standard flow cytometric software,FACSDiva *** of the outcome of the fertility treatment is included for 137 patients receiving either intrauterine inseminations(IUI)or timed coitus(TC).The results show that the chance of pregnancy decli nes as DFI in *** also found that the male DFI affects the chanee of pregnancy independent of the female *** have shown that a standard flow cytometric software can be used when determi ning a clinical releva nt *** findings are a sign ificant step toward impleme nting the an alysis as a part of the routi ne,in・house diag no sing of the male fertility patient and subseque ntly optimizing the treatme nt course of the couple with reduced human and financial costs.

关键词： DNA fragme ntation flow cytometry in-house an alysis in trauteri ne in semi natio n Sperm Chromati n Structure Assay spermatozoa

Salvage anastomosis in free PAP-flap breast reconstruction:What about free flap neovascularization?

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Chinese Journal of Plastic and Reconstructive Surgery 2023年第4期5卷 178-181页

作者： Michael Hepp Aline Berners Christine Deconinck genevieve Pirson Maxime Servaes Philippe Fosseprez Department of Plastic Reconstructive and Aesthetic SurgeryCHU UCL NamurNamur 5000Belgium

Since the emergence of microsurgery in reconstructive surgery, free flaps have become a key tool in the management of patients with breast cancer. One such flap is the profunda artery perforator(PAP) flap. To date,there is no scientific consensus on whether voluminous free flaps remain dependent on their vascular pedicle throughout their lifespan. Therefore, the pedicle should always be carefully protected during revision *** this article, we review the case of a middle-aged woman who suffered a pedicle transection needing reanastomosis during revision surgery six months after free-flap breast reconstruction. A 52-year-old woman who noticed a firm nodule in her right breast and armpit was referred to our department for surgical management. The Caucasian woman presented with no significant medical history or symptoms at the first consultation. Ultrasound-guided biopsy confirmed an invasive grade Ⅲ lobular carcinoma. Following staging,the patient underwent neoadjuvant chemotherapy before a right mastectomy with a complete homolateral axillary lymph node dissection and postoperative radiotherapy. One year after completing radiotherapy, free flap reconstruction with a PAP flap was performed, and six months later, revision surgery was required to enhance the volume of the reconstructed breast with a tissue expander and later an implant. Unfortunately,pedicle transection occurred during revision surgery, causing complete devascularization of the flap, which was confirmed by intraoperative Indocyanine Green imaging. The authors elected to perform salvage reanastomosis during the surgery. In keeping with the author’s 23-year experience with free flaps, the vascular pedicle should always be preserved in voluminous free flaps, as neovascularization alone may not ensure whole flap survival. The authors suggest always attempting re-anastomosis if vessels are compromised during revision surgery.

关键词： Free flap Autonomy Vascular pedicle Revascularization PAP flap Microsurgery

More patients should undergo surgery after sigmoid volvulus

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World Journal of Gastroenterology 2014年第48期20卷 18384-18389页

作者： anne Kathrine Wewer Ifversen Daniel Willy Kjaer Department of Surgery P Aarhus University Hospital 8000 Aarhus C Denmark

AIM: To assess the outcome of patients treated conservatively vs surgically during their first admission for sigmoid volvulus.

关键词： Sigmoid volvulus Surgery Resection Percutaneous endoscopic colostomy Recurrence