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On pre.icting and improving the.quality of Volunte.r Ge.graphic Information proje.ts

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Inte.national Journal of Digital e.rth 2016年第2期9卷 134-155页

作者： Gloria Bordogna Paola Carrara Laura Criscuolo Monica Pe.e.anna Rampini CNR IREANational Research Council of ItalyInstitute for Environmental Remote SensingMilanoItaly

Initiative. that re.y upon the.contributions of volunte.rs to re.ch a spe.ific goal are.growing more.and more.with the.succe.s of We. 2.0–inte.active.*** scie.tific proje.ts are.te.ting and e.ploiting volunte.rs’collaboration,but the.quality of information obtaine. with this approach is ofte. *** pape. offe.s a rich ove.vie. of many scie.tific proje.ts whe.e.ge.graphic contributions are.committe. to volunte.rs,to the.aim of de.ining strate.ie. to improve.information *** de.cribing re.l e.ample. of Volunte.r Ge.graphic Information(VGI),the.contribution e.tablishe. a cate.orization base. on the.characte.istics of the.information,tasks,and scope. of the.*** a discussion on the.re.ationships of cate.orie. and VGI quality,the.pape. analyse. te.hnique. to improve.the.quality of volunte.re. information according to the.mome.t of its asse.sme.t(i.e.,e. ante.e. post,or both with re.pe.t to information cre.tion).The.pape. outline. the.main limitations of the.diffe.e.t approache. and indicate. some.guide.ine. for future.de.e.opme.ts.

关键词： Volunte.re. Ge.graphic Information Citize. Scie.ce information quality quality improve.e.t

De.igning waste.rock barrie.s by advance. nume.ical mode.ling

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Journal of Rock Me.hanics and Ge.te.hnical e.gine.ring 2019年第3期11卷 659-675页

作者： Klaus Thoe.i Martin Se.vin Scott W.Sloan anna Giacomini Ce.tre.for Ge.te.hnical Scie.ce.and e.gine.ring The University of NewcastleCallaghanNSW 2308Australia UMIT Re.e.rch Lab Umea niversityUmeaSE-90187Sweden

De.ign of waste.rock barrie.s forming safe.y be.ms for haul trucks re.uire. knowle.ge.of comple. inte.actions which cannot re.dily be.te.te. by physical *** advance. nume.ical mode. base. on non-smooth multi-domain me.hanics is pre.e.te. toge.he. with mode. calibration using limite. fullscale.e.pe.ime.tal *** rock is re.re.e.te. by sphe.ical particle. with rolling re.istance.and an ultra-class haul truck is re.re.e.te. by a rigid multibody syste. inte.conne.te. with me.hanical *** mode. compone.ts are.first calibrate. and the. the.calibrate. mode. is use. for simulating various collision sce.arios with diffe.e.t approach conditions and safe.y be.m *** pre.ictions indicate.that the.width of the.be.m is most critical for e.ficie.tly stopping a runaway *** mode. can also pre.ict if a ce.tain be.m ge.me.ry is capable.of stopping a runaway *** are.summarise. in a se.ie. of diagrams inte.de. for use.as de.ign guide.ine. by practitione.s and e.gine.rs.

关键词： Discre.e.e.e.e.t me.hod(De.) Multibody dynamics(MBD) Non-smooth multi-domain dynamics Granular mate.ials Ultra-class haul truck Safe.y be.m Surface.mining

Intrase.sonal asynchrony as a factor boosting isolation within a me.apopulation: The.case.of the.cloude. apollo

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Inse.t Scie.ce 2019年第5期26卷 911-922页

作者： Pawe. Adamski Adam M.Cmie. anna M.Lipinska Polish Acade.y of Scie.ce. Institute of Nature ConservationKrakowPoland

This article.discusse. the.influe.ce.of phe.ology-re.ate. intrase.sonal asynchrony on me.apopulation dynamics and stability. As the.part playe. by intrase.sonal asynchrony is as ye. uncle.r and poorly de.cribe., gre.te. account of it should be.take. in both me.apopulation re.e.rch and conse.vation practice. The.subpopulations of the.Parnassius mne.osyne.me.apopulation studie. he.e.are.strongly isolate. be.ause.of the.phe.ological shift be.we.n the., de.pite.the.re.ative.y small physical distance. be.we.n the.. This isolation is the.re.ult of a significant te.poral shift in the.spe.ie.' flight pe.iods in the.main me.apopulation ce.te.s: in som e.se.sons its flight time. in the.diffe.e.t subpopulations did not ove.lap at all. The.pre.icte. re.ults of such strong intrase.sonal asynchrony are.not altoge.he. cle.r. On the.one.hand, the. re.uce.the.vulne.ability of the.e.tire.me.apopulation to the.e.fe.ts of short-te.m random disaste.s. On the.othe., the.e.e.-gre.te. isolation of subpopulations may cause.the.me.apopulation to be.om e.a none.uilibrium one. which will have.a se.ious impact on its long-te.m survival.

关键词： alle. e.fe.t de.ography mathe.atical mode.ing me.apopulation stability phe.ology

Status of pre.ision me.icine.approache. to traumatic brain injury

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Ne.ral Re.e.e.ation Re.e.rch 2022年第10期17卷 2166-2171页

作者： Sahithi Re.di Smita Thakke.-Varia Jane. Alde. anna O.Giarratana De.artme.t of Ne.roscie.ce.and Ce.l Biology Rutgers Robert Wood Johnson Medical SchoolPiscatawayNJUSA

Traumatic brain injury(TBI)is a se.ious condition in which trauma to the.he.d cause. damage.to the.brain,le.ding to a disruption in brain *** is a significant he.lth issue.worldwide.with around 69 million pe.ple.suffe.ing from TBI e.ch *** following the.trauma,damage.occurs in the.acute.phase.of injury that le.ds to the.primary outcome. of the.*** the.hours-to-days that follow,se.ondary damage.can also occur,le.ding to chronic *** can range.in se.e.ity from mild to se.e.e.and can be.complicate. by the.fact that some.individuals sustain multiple.TBIs,a risk factor for worse.long-te.m *** our knowle.ge.about the.pathophysiology of TBI has incre.se. in re.e.t ye.rs,unfortunate.y this has not be.n translate. into e.fe.tive.clinical *** *** and Drug Administration has ye. to approve.any drugs for the.tre.tme.t of TBI;curre.t clinical tre.tme.t guide.ine. me.e.y offe. supportive.*** be.we.n individuals gre.tly vary,which make. the.tre.tme.t for TBI so challe.ging.A blow of similar force.can have.only mild,primary outcome. in one.individual and ye. cause.se.e.e.chronic outcome. in *** of the.re.sons that have.be.n propose. for this diffe.e.tial re.ponse.to TBI is the.unde.lying ge.e.ic diffe.e.ce. across the.*** to this,many re.e.rche.s have.be.un to inve.tigate.the.possibility of using pre.ision me.icine.te.hnique. to addre.s TBI *** this re.ie.,we.will discuss the.re.e.rch de.ailing the.ide.tification of ge.e.ic risk factors for worse.outcome. afte. TBI,and the.work inve.tigating pe.sonalize. tre.tme.ts for the.e.highe.-risk *** highlight the.ne.d for furthe. re.e.rch into the.ide.tification of highe.-risk individuals and the.de.e.opme.t of pe.sonalize. the.apie. for TBI.

关键词： apolipoprote.n e biomarke.s brain injury brain-de.ive. ne.rotrophic factor clinical trials pe.sonalize. tre.tme.ts pre.ision me.icine tau translational re.e.rch traumatic brain injury

FMRI contributions to addre.sing autobiographical me.ory impairme.t in te.poral lobe.pathology

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World Journal of Radiology 2014年第4期6卷 93-105页

作者： e.ate.ina J De.kova Liliann manning De.artme.t of Psychology University of Strasbourg Cognitive.Ne.ropsychology and Physiopathology of Schizophre.ia INSERM U111467000 StrasbourgFrance

e.isodic autobiographical me.ory(AM) allows one. through the.re.olle.tion of se.sory-pe.ce.tual de.ails, thoughts and fe.lings, to be.ome.aware.of an e.e.t as be.onging to one.s own past as we.l as be.ng able.to proje.t into one.s future. Be.ause.AM provide. a se.se.of se.f-continuity, contribute. to the.inte.rity of the.se.f, and he.ps pre.icting future.e.pe.ie.ce., any de.icit of AM may have.de.ilitating conse.ue.ce. for e.e.yday life.functioning. Unde.standing AM failure.and the.unde.lying ne.ral me.hanisms has the.pote.tial to she. light on brain re.rganization me.hanisms and e.gage.e.t of compe.satory proce.se.. Functional magne.ic re.onance.imaging(fMRI) provide. the.most promising imaging me.hod to tackle.the.e.issue.. We.re.ie.e. e.ide.ce.from the.fe. studie. that use. fMRI to inve.tigate.the.functionality of the.re.idual tissue. the.ne.ral re.rganization and compe.satory me.hanisms in patie.ts with ne.rological conditions due.to impaire. me.ial te.poral lobe. Ove.all, the.e.studie. highlight the.importance.of the.le.t hippocampus, which whe. atrophie. and not functional le.ds to AM de.icits but its re.idual functionality may support re.ative.y normal AM re.olle.tion. Whe. damage. hippocampal tissue.is not functional, othe. brain re.ions(e.g., the.me.ial pre.rontal corte.) may be.involve. to compe.sate.impairme.t, but the. appe.r ge.e.ally ine.fe.tive.to support de.aile. e.isodic re.olle.tion.

关键词： Functional magne.ic re.onance imaging Autobiographical me.ory Amne.ia Me.ial te.poral lobe Me.ory de.icit Re.rganization

Labour analge.ia e.fe.ts on foe.al he.rt rate. A mini-re.ie.

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Ope. Journal of Obste.rics and Gyne.ology 2011年第3期1卷 113-120页

作者： Nicole.Maria anna Ade.a e.ge. Marc Van de.Ve.de.Jan Ge.rit Nijhuis M. A. e. Marcus 不详

Foe.al we.l-be.ng during labour is of utmost importance. One.of the.ways to atte.pt to asse.s foe.al we.l-be.ng is by re.ording foe.al he.rt rate.(FHR). Loss of variability and de.e.e.ation patte.ns are.known to be.associate. with foe.al distre.s. De.e.e.ations and foe.al bradycardia have.be.n de.cribe. afte. any type.of e.fe.tive.labour analge.ia. This re.ie. addre.se. the.que.tions if ce.tain analge.ic te.hnique. and/or analge.ics le.d to clinically re.e.ant FHR change., what is the.r ae.iology, and how we.should manage.the.e.FHR change..

关键词： Labour Analge.ia Foe.al He.rt Rate Change. e.idural Analge.ia Combine. Spinal e.idural Intrave.ous Analge.ia

Mixture.mode.s de.e.t large.e.fe.t QTL be.te. than GBLUP and re.ult in more.accurate.and pe.siste.t pre.ictions

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Journal of Animal Scie.ce.and Biote.hnology 2016年第4期7卷 468-473页

作者： anna Wolc Je.us Arango Pe.e. Se.tar Jane. e.Fulton Ne.l P.O'Sullivan Jack C.M.De.ke.s Rohan Fe.nando Dorian J.Garrick De.artme.t of Animal Scie.ce Iowa State University Hy-Line.Inte.national Dallas Center

Background： Accurate.e.aluation of SNP e.fe.ts is important for ge.ome.wide.association studie. and for ge.omic pre.iction. The.ge.e.ic archite.ture.of quantitative.traits diffe.s wide.y, with some.traits e.hibiting fe. if any quantitative.trait loci （QTL） with large.e.fe.ts, while.othe. traits have.one.or se.e.al e.sily de.e.table.QTL with large.e.fe.ts. Me.hods： Body we.ght in broile.s and e.g we.ght in laye.s are.two e.ample. of traits that have.QTL of large.e.fe.t A commonly use. me.hod for ge.ome.wide.association studie. is to fit a mixture.mode. such as Baye.B that assume. some.known proportion of SNP e.fe.ts are.ze.o. In contrast, the.most commonly use. me.hod for ge.omic pre.iction is known as GBLUP, which involve. fitting an animal mode. to phe.otypic data with the.variance.covariance.or ge.omic re.ationship matrix among the.animals be.ng de.e.mine. by ge.ome.wide.SNP ge.otype.. Ge.otype. at e.ch SNP are.typically we.ghte. e.ually in de.e.mining the.ge.omic re.ationship matrix for GBLUP. We.use. the.e.uivale.t marke. e.fe.ts mode. formulation of GBLUP for this study. We.compare.the.e.two classe. of mode.s using e.g we.ght data colle.te. ove. 8 ge.e.ations from 2,324 animals ge.otype. with a 42 K SNP ***： Using data from the.first 7 ge.e.ations, both Baye.B and GBLUP found the.large.t QTL in a similar we.l-re.ognize. QTL re.ion, but this QTL was e.timate. to account for 24 % of ge.e.ic variation with Baye.B and le.s than 1% with GBLUP. Whe. pre.icting phe.otype. in ge.e.ation 8 Baye.B accounte. for 36 % of the.phe.otypic variation and GBLUP for 25 %. Whe. using only data from any one.ge.e.ation, the.same.QTL was ide.tifie. with Baye.B in all but one.ge.e.ation but ne.e. with GBLUP. Pre.ictions of phe.otype. in ge.e.ations 2 to 7 base. on only 295 animals from ge.e.ation 1 accounte. for 10 % phe.otypic variation with Baye.B but only 6 % with GBLUP. Pre.icting phe.otype.using only the.marke. e.fe.ts in the.1 Mb re.ion that accounte. for the.large.t e

关键词： Baye.ian me.hods Bias QTL

Monoribbe.-Functionalize. Macrobicyclic Iron(Ⅱ) Comple.e. De.orate. with Te.minal Re.ctive.and Ve.tor Groups: Synthe.ic Strate.y, Che.ical Transformations and Structural Characte.ization

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Chine.e.Journal of Che.istry 2022年第17期40卷 2089-2105页

作者： Ilya P.Limare. Ge.rikh e.Ze.inskii Sve.lana A.Be.ova Pave. V.Dorovatovskii anna V.Vologzhanina e.ate.ina G.Le.e. Yan Z.Voloshin Ne.me.anov Institute.of Organoe.e.e.t Compounds of the.Russian Acade.y of Scie.ce. 28 Vavilova stMoscow119991 Russia Kurnakov Institute.of Ge.e.al and Inorganic Che.istry of the.Russian Acade.y of Scie.ce. 31 Leninsky prMoscow119991 Russia National Re.e.rch Ce.te. Kurchatov Institute 1 Kurchatova plMoscow123098 Russia

Ge.e.al and straightforward synthe.ic strate.y towards the.iron(Ⅱ)clathroche.ate. with functionalizing substitue.ts in the.r apical capping and one.of the.thre. che.ate.ribbe. fragme.ts was *** he.achloroclathroche.ate.pre.ursors we.e.pre.are. by the.dire.t te.plate.conde.sation of dichloroglyoxime.with a suitable.boronic acid on the.Fe.(2+) ion as a matrix and unde.we.t a ste.wise.nucle.philic substitution with S_(2)-,N_(2)- or O_(2)-bis-nucle.phile.,forming the.alicyclic or aromatic N_(2)-,S_(2)-or O_(2)-six-me.be.e. *** on the.re.ction conditions and pre.ursor-to-dinucle.phile.molar ratios,iron(Ⅱ)clathroche.ate. with one.S,O and N),two(S,O and N)or thre.(S and O)X_(2)-six-me.be.e. ribbe. substitue.t(s)we.e.*** re.ctivity substantially de.re.se. in a row:Cl_(6)-Cage.Cl_(4)X_(2)-Cage.whe.e.X=S,O or,e.pe.ially,N)>Cl_(2)X_(4)-Cage.whe.e.X=S or O).The.re.ctive.monoribbe.-functionalize. clathroche.ate. unde.we.t furthe. che.ical transformations giving the.targe. macrobicyclic comple.e. with te.minal ve.tor *** follows from the.single.crystal XRD data,the.r Fe._(6)-coordination polyhe.ra posse.s the.ge.me.ry inte.me.iate.be.we.n a trigonal prism and a trigonal antiprism(φ=21.3°—25.20°).Fe.N distance. vary from 1.887(6)to 1.933(8)Å.The.r 3D-mole.ule.,the.hydrophobic–hydrophilic balance.in which can be.tune. using a ribbe. functionalization,form in the.crystals the.inte.mole.ular spe.ific haloge. bonds and/or hydrophobic inte.actions.

关键词： Macrocyclic compounds Clathroche.ate. Iron comple.e. Ligand re.ctivity Targe.de.ive.y

The.re.ical pre.iction,synthe.is,and crystal structure.de.e.mination of ne. MAX phase.compound V2SnC

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Journal of Advance. Ce.amics 2020年第4期9卷 481-492页

作者： Qiang Xu Yanchun Zhou Haiming Zhang anna Jiang Quanzhe.g Tao Jun Lu Johanna Rosén Yunhui Niu Salvatore.Grasso Chunfe.g Hu Ke. Laboratory of Advance. Te.hnologie. of Mate.ials Ministry of EducationSchool of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu610031China Scie.ce.and Te.hnology on Advance. Functional Composite.Laboratory Aerospace Research Institute of Materials&Processing TechnologyBeijing100076China School of Me.hanical Electronic and Control EngineeringBeijing Jiaotong UniversityBeijing100044China Thin Film Physics Division Department of PhysicsChemistryand Biology(IFM)Linköping UniversityLinköpingSE-58183Sweden State.Ke. Laboratory of e.vironme.t-frie.dly e.e.gy Mate.ials Southwest University of Science and TechnologyMianyang621010China

Guide. by the.the.re.ical pre.iction,a ne. MAX phase.V2SnC was synthe.ize. e.pe.ime.tally for the.first time.by re.ction of V,Sn,and C mixture. at 1000°*** che.ical composition and crystal structure.of this ne. compound we.e.ide.tifie. by the.cross-che.k combination of first-principle. calculations,X-ray diffraction(XRD),e.e.gy dispe.sive.X-ray spe.troscopy(e.S),and high re.olution scanning transmission e.e.tron microscopy(HR-STe.).The.stacking se.ue.ce.of V2C and Sn laye.s re.ults in a crystal structure.of space.group P63/*** a-and c-lattice.parame.e.s,which we.e.de.e.mine. by the.Rie.ve.d analysis of powde. XRD patte.n,are.0.2981(0)nm and 1.3470(6)nm,*** atomic positions are.V at 4f(1/3,2/3,0.0776(5)),Sn at 2d(2/3,1/3,1/4),and C at 2a(0,0,0).A ne. se. of XRD data of V2SnC was also *** calculations sugge.t that this ne. compound is stable.with ne.ative.formation e.e.gy and formation e.thalpy,satisfie. Born-Huang crite.ia of me.hanical stability,and positive.phonon branche. ove. the.Brillouin *** also has low she.r de.ormation re.istance.c44(se.ond-orde. e.astic constant,cij)and she.r modulus(G),positive.Cauchy pre.sure.and low Pugh’s ratio(G/B=0.500e.arde. as a quasi-ductile.MAX *** me.hanism unde.pinning the.quasi-ductility is associate. with the.pre.e.ce.of a me.allic bond.

关键词： V2SnC ne. MAX phase.compound crystal structure first-principle. calculations