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Microbial phenolic metabolites are associated with better frontal lobe cognition

Food Science and Human Wellness 2024年

作者： Inés Domínguez-López Isabella Parilli-Moser anna vallverdú-queralt anna Tresserra-Rimbau Cinta Valls-Pedret Zenaida Vázquez-Ruiz Olga Casta?er Ramon Estruch Emili Ros Rosa M.Lamuela-Raventós Lipid Clinic Endocrinology and Nutrition Service Institut d'Investigacions Biomèdiques August Pi i Sunyer Hospital Clínic 08036 Barcelona Spain Unit of Cardiovascular Risk and Nutrition Institut Hospital del Mar de Investigaciones Médicas (IMIM) Department of Preventive Medicine and Public Health University of Navarra Departament de Nutrició Ciències de l'Alimentació i Gastronomía Facultat de Farmacia Universitat de Barcelon (UB) Av.de Joan XXII Department of Endocrinology Hospital Clinic IDIBAPS Barcelona Spain Department of Internal Medicine Hospital Clinic Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS) University of Barcelona CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) Instituto de Salud Carlos III Institut de Nutrició i Seguretat Alimentària (INSA) Universitat de Barcelona (UB)

With increasing life expectancy， neurodegenerative diseases have become one of the leading causes of ill-health in the elderly. Preventive strategies include following healthy diets， such as the Mediterranean diet， which is particularly rich in polyphenols， bioactive compounds with neuroprotective properties. The aim of this study was to assess the association of microbial phenolic metabolites (MPM) with cognition. This cross-sectional analysis was performed with 200 participants of the PREDIMED trial (Barcelona-Clinic recruitment center). A novel method based on liquid chromatography coupled to mass spectrometry was used to identify urinary MPM (protocatechuic acid， enterodiol glucuronide， enterolactone glucuronide， urolithin B glucuronide， and vanillic acid glucuronide)， and cognitive function was evaluated with neuropsychological tests. Multivariable-adjusted ordinary least squares regression was used to assess the associations between cognitive function and MPM， and a score was calculated as the weighted sum of MPM. A higher MPM score was associated with better frontal lobe function. Among individual metabolites， vanillic acid glucuronide was correlated with frontal cognitive performance. Participants with higher concentrations of vanillic acid glucuronide and urolithin B glucuronide obtained better scores in the Color Trail Test part 2. A higher score for urinary multi-MPM was associated with better frontal cognitive performance in an older Mediterranean population.

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A modeling framework for the integration of electrical and thermal energy systems in greenhouses

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Building Simulation 2022年第5期15卷 779-797页

作者： queralt Altes-Buch Sylvain Quoilin Vincent Lemort Energy Systems Research Unit Faculty of Applied SciencesUniversity of LiegeAllee de la Decouverte 774000 LiegeBelgium

Greenhouse horticulture is associated to a significant energy consumption in temperate countries,mainly for lighting and for ***,the potential for energy optimization and energy savings is high but requires detailed models capable of considering various system configurations and control *** paper provides an open-source modeling framework capable of simulating and optimizing the design and the control of both the greenhouse and the generation systems covering all energy *** proposed model is composed of sub-models from different scientific fields:a greenhouse climate model,a crop yield model,a large number of energy generation and storage units models and different rule-based control *** association of such state-of-the-art models in a single framework provides a powerful tool for optimization purposes and allows the definition of completely customized systems by means of an object-oriented *** this work,various control strategies are defined and simulated,thus demonstrating the capabilities of the proposed *** indicate that,by performing minor changes to the control of the thermal screen,heating consumption can be reduced by 3%without any loss in crop *** control of heat-generation units also has a significant impact on the operational costs,which vary by up to 17%when self-consumption levels are accounted for in the control strategy.

关键词： greenhouse climate model CHP greenhouse climate control system integration energy management

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Interaction of silver nanoparticles with mediterranean agricultural soils: Lab-controlled adsorption and desorption studies

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Journal of Environmental Sciences 2019年第9期31卷 205-216页

作者： Laura Torrent Eva Margui Ignasi queralt Manuela Hidalgo Monica Iglesias Department of Chemistry University of Girona C/M. Aurelia Capmany 69 17003 Girona Spain Institute of Environmental Assessment and Water Research (IDAEA-CSIC) C. Jordi Girona 28-26 08034 Barcelona Spain

The production of silver nanoparticles(AgNPs) has increased tremendously during recent years due to their antibacterial and physicochemical properties. As a consequence, these particles are released inevitably into the environment, with soil being the main sink of disposal. Soil interactions have an effect on AgNP mobility, transport and bioavailability. To understand AgNP adsorption processes, lab-controlled kinetic studies were *** tests performed with five different Mediterranean agricultural soils showed that cation exchange capacity and electrical conductivity are the main parameters controlling the adsorption processes. The adsorption kinetics of different sized(40, 75, 100 and 200 nm)and coated(citrate, polyvinylpyrrolidone and polyethyleneglycol(PEG)) AgNPs indicated that these nanoparticle properties have also an effect on the adsorption *** assess the mobility and bioavailability of AgNPs and to determine if their form is maintained during adsorption/desorption processes, loaded soils were submitted to leaching tests three weeks after batch adsorption studies. The DIN 38414-S4 extraction method indicated that AgNPs were strongly retained on soils, and single-particle inductively coupled plasma mass spectrometry confirmed that silver particles maintained their nanoform, except for 100 nm PEG-AgNPs and 40 nm citrate-coated AgNPs. The DTPA(diethylenetriaminepentaacetic acid) leaching test was more effective in extracting silver,but there was no presence of AgNPs in almost all of these leachates.

关键词： Silver nanoparticles Agricultural soils Sorption kinetics Leaching tests Single-particle inductively coupled plasma mass spectrometry

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Building Expertise on FAIR Through Evolving Bring Your Own Data(BYOD) Workshops: Describing the Data, Software, and Management-focused Approaches and Their Evolution

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Data Intelligence 2024年第2期6卷 429-456页

作者： César H.Bernabé Lieze Thielemans Rajaram Kaliyaperumal Claudio Carta Shuxin Zhang Celia W.G.van Gelder Nirupama Benis Luiz Olavo Bonino da Silva Santos Ronald Cornet Bruna dos Santos Vieira Nawel Lalout Ines Henriques Alberto Camara Ballesteros Kees Burger Martijn G.Kersloot Friederike Ehrhart Esther van Enckevort Chris T.Evelo Alasdair J.G.Gray Marc Hanauer Kristina Hettne Joep de Ligt Arnaldo Pereira Nuria queralt-Rosinach Erik Schultes Domenica Taruscio Andra Waagmeester Mark D.Wilkinson Egon L.Willighagen Mascha Jansen Barend Mons Marco Roos Annika Jacobsen Biosemantics Group Department of Human GeneticsLeiden University Medical CentreLeidenThe Netherlands NIHR Academic Fellow in General Practice University College London and The Royal Free NHS Foundation Trust National Centre for Rare Diseases Istituto Superiore di SanitaRomeItaly Department of Medical Informatics Amsterdam UMC location University of AmsterdamMeibergdreef 9AmsterdamThe Netherlands Amsterdam Public Health Methodology&Digital HealthAmsterdamThe Netherlands Health-Rl UtrechtThe Netherlands Semantics Services and Cybersecurity groupUniversity of TwenteEnschedeThe Netherlands Department of Medical Imaging Radboud Institute for Health SciencesRadboud University Medical CenterNijmegenThe Netherlands Department of Medical BioSciences Radboud University Medical CenterNijmegenThe Netherlands The Duchenne Parent Project VeneendaalThe Netherlands Departamento de Biotecnologia-Biologia Vegetal Escuela Tecnica Superior de Ingenieria AgronomicaAlimentaria y de BiosistemasCentro de Biotecnologia y Genomica de PlantasUniversidad Politecnica de Madrid(UPM)-Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria-CSIC(INIA-CSIC).Campus MontegancedoPozuelo de Alarcon(Madrid)Spain Castor AmsterdamThe Netherlands Department of Bioinformatics-BiGCaT Maastricht UniversityMaastrichtThe Netherlands University Medical Center Groningen University of GroningenGroningenThe Netherlands Maastricht Centre for Systems Biology(MaCSBio) Maastricht UniversityMaastrichtThe Netherlands Department of Computer Science Heriot-Watt UniversityEdinburghUK INSERM US14-OrphanetPlateforme Maladies RaresParisFrance Centre for Digital Scholarship Leiden University LibrariesThe Netherlands Center for Molecular Medicine Cancer Genomics NetherlandsDepartment of GeneticsUniversity Medical Center UtrechtUniversity UtrechtThe Netherlands University of Aveiro DETI/IEETAAveiroPortugal GO FAIR Foundation LeidenThe Netherlands The Leiden Academic Center for Drug Research LeidenThe Netherlands Micel

Since 2014,"Bring Your Own Data"workshops(BYODs)have been organised to inform people about the process and benefits of making resources Findable,Accessible,Interoperable,and Reusable(FAIR,and the FAIRification process).The BYOD workshops'content and format differ depending on their goal,context,and the background and needs of ***-focused BYODs educate domain experts on how to make their data FAIR to find new answers to research ***-focused BYODs promote the benefits of making data FAIR and instruct project managers and policy-makers on the characteristics of FAIRification ***-focused BYODs gather software developers and experts on FAIR to implement or improve software resources that are used to support ***,these BYODs intend to foster collaboration between different types of stakeholders involved in data management,curation,and reuse(*** experts,trainers,developers,data owners,data analysts,FAIR experts).The BYODs also serve as an opportunity to learn what kind of support for FAIRification is needed from different communities and to develop teaching materials based on practical examples and *** this paper,we detail the three different structures of the BYODs and describe examples of early BYODs related to plant breeding data,and rare disease registries and biobanks,which have shaped the structure of the *** discuss the latest insights into making BYODs more productive by leveraging our almost ten years of training experience in these workshops,including successes and encountered ***,we examine how the participants'feedback has motivated the research on FAIR,including the development of workflows and software.

关键词： FAIR FAIRification FAIR expertise Bring Your Own Data Workshop BYOD

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Extending the geoelectric model of the Betic crust （Spain） towards West using 3D MT inversion techniques

Extending the geoelectric model of the Betic crust （Spain）...

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The19thInternationalWork...

作者： MARTI anna queralt Pilar LEDO Juanjo ROSELL Oriol MARCUELLO Alex ROCA Eduard Dept.de Geodinàmica i Geofísica Facultat de GeologiaUniversitat de BarcelonaSpain

＜正＞The Betic Chain（Spain）is an Alpine orogen located at the western end of the Mediterranean,where magnetotelluric studies have been carried out since the 90’s,which have allowed to better understand its complex...

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牛津城

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海外英语 2010年第9期 48-50页

作者： James queralt 刘瑞海（译）

牛津是世界上最著名的英国城市之一，它有许多壮观无比的大学建筑，还有许多引人入胜的地方……

关键词：英语课外阅读翻译方法阅读材料

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Improving Water Quantity and Quality Supply Security by Managed Artificial Recharge Technologies in the Lower Llobregat Aquifers Integrated into a Conjunctive Surface and Groundwater Management Scheme for Barcelona,Spain

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Journal of Environmental Science and Engineering(A) 2020年第4期9卷 119-139页

作者： Enric queralt Xavier Bernat Emilio Custodio Llobregat Delta Water Users Association 08820 eL Prat de LlobregatBarcelonaSpain CETAQUA Water Technology CenterCornellàde Llobregat Barcelona 08934Spain Department of Civil and Environmental Engineering Polytechnical University of CataloniaBarcelona 08034Spain Royal Academy of Sciences of Spain Spain

The large concentration of human population,industry and services in the Metropolitan Area of Barcelona has to confront scarce water resources,serious seasonal and inter-annual variations and quality deficiencies in the sources.A large fraction of these water resources are in the medium-size Llobregat River basin and the remaining ones correspond to a surface water transfer,seawater desalination and wastewater *** dominated water resources availability before ***,water supply has evolved progressively to integrated water resources management,which includes serious water quality concerns to deal with population density,river pollution,seawater intrusion in the main aquifer,and brine generation in the mid Llobregat basin due to old mining of saline *** role of the alluvial aquifers has progressively evolved from being the main water source to reserve storage to cope with seasonal and drought water resources ***-enhanced recharge and artificial recharge are needed to assure enough groundwater storage before surface water becomes scarce and/or suffers a serious temporal loss of *** river recharge started in *** river water injection in dual-purpose wells was put into operation in the early *** and pond recharge was added later,as well as a deep well injection barrier along the coast to reduce seawater intrusion and to allow increased groundwater abstraction in moments of water *** is a progressive evolution from solving water quantity problems to consideration of water quality improvement during recharge,with attention to emergent concern pollutants in river water and in reclaimed water to be considered for artificial *** of artificial recharge operation activities has been introduced and research is being carried out on the difficult behavior to degrade organic pollutants during infiltration and in the *** paper presents the different activities ca

关键词： Enhanced river recharge artificial aquifer recharge integrated water resources management Llobregat River basin,Barcelona

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