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Translation and cross-cultural adaptation of the Kidney Transplant Questionnaire 25 to Greek

World Journal of Transplantation 2024年第2期14卷 148-154页

作者： Vasileios Koutlas Eirini Tzalavra Vasileios Tatsis Charalampos Pappas Stavroula Vovlianou Stefanos Bellos anila duni Eleni Stamellou Konstantinos I Tsamis Michail Mitsis Evangelia Dounousi Department of Surgery and Kidney Transplant Unit University Hospital of IoanninaIoannina 45500EpirusGreece Department of Surgery Faculty of MedicineSchool of Health SciencesUniversity of IoanninaIoannina 45110EpirusGreece Department of Nephrology University Hospital of IoanninaIoannina 45500EpirusGreece Department of Nephrology General Hospital of KavalaKavala 65500Greece Department of Physiology Faculty of MedicineSchool of Health SciencesUniversity of IoanninaIoannina 45110EpirusGreece Department of Nephrology Faculty of MedicineSchool of Health SciencesUniversity of IoanninaIoannina 45110EpirusGreece

BACKGROUND Kidney transplantation leads to continuous improvement in the survival rates of kidney transplant recipients(KTRs)and has been established as the treatment of choice for patients with end-stage kidney ***-related quality of life(HRQoL)has become an important outcome *** is highly important to develop reliable methods to evaluate HRQoL with disease-specific *** To translate the disease-specific instrument Kidney Transplant Questionnaire 25(KTQ-25)to the Greek language and perform a cross-cultural *** The translation and adaptation of the original English version of the KTQ-25 to the Greek language were performed based on the International Quality of Life RESULTS Eighty-four KTRs(59 males;mean age 53.5±10.7 years;mean estimated glomerular filtration rate 47.7±15.1 mL/min/1.73 m2;mean transplant vintage 100.5±83.2 months)completed the Greek version of the KTQ-25 and the 36-item Short-Form Health Survey,and the results were used to evaluate the reliability of the Greek *** Cronbach alpha coefficients for all the KTQ-25 dimensions were satisfactory(physical symptoms=0.639,fatigue=0.856,uncertainty/fear=0.661,appearance=0.593,emotions=0.718,total score=0.708).The statistically significant correlation coefficients among the KTQ-25 dimensions ranged from 0.226 to *** correlation coeffi-cients of the KTQ-25 dimensions with the SF-36 physical component summary(PCS)ranged from 0.196 to 0.550;the correlation coefficients of the KTQ-25 with the SF-36 mental component summary(MCS)ranged from 0.260 to 0.655;and the correlation coefficients of the KTQ-25 with the total scores with the SF-36 PCS and MCS were 0.455 and 0.613,*** According to the findings,the Greek version of the KTQ-25 is valid and reliable for administration among kidney transplant patients in Greece.

关键词： Kidney Transplant Questionnaire 25 Kidney transplantation Kidney transplant recipients Health-related quality of life Quality of life

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The Impact of Physiotherapy Interventions on the Elderly Population with Mental Health Conditions at Chainama Hills College Hospital in Zambia. A Pre-Post Single Sample Study Design

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Open Journal of Therapy and Rehabilitation 2024年第2期12卷 160-173页

作者： Bibi Mwanatambwe Phiri Martha Banda Chalwe Margaret Mweshi Loveness anila Nkhata Department of Physiotherapy Chainama Hills Hospital Lusaka Zambia School of Health Sciences Department of Physiotherapy University of Zambia Lusaka Zambia

Background: Physical functional decline is common among elderly individuals with mental disorders, worsening their symptoms. Physiotherapy interventions have shown some evidence in improving physical function and mental health outcomes in this population. This study aimed to assess the impact of physiotherapy interventions on the elderly with mental health conditions at Chainama Hills College Hospital in Zambia. Methods: A pre-post single sample design was used to track patient progress over six weeks, with 10 physiotherapy sessions. The study population (N = 30) comprised of all elderly individuals with mental health conditions, encompassing both men and women, who were hospitalized during the research period. The Katz Index of Activities of Daily Living and the six-minute walk test were evaluated before and after the intervention. The IBM SPSS version 26 was used to analyze data and results were presented as mean ± SD with a 95% confidence interval. The variables were described in terms of their mean, SD, and range. A significance level of 0.05 was used for a paired T-test to detect changes and multiple logistic regression was used to identify factors associated with mental health. Results: Following the intervention, the percentage of participants achieving full function and independence increased significantly to 96.7% from the initial 73.3%, supported by a 95% CI = [0.82 - 0.99]. There was also a notable decrease in the proportion of individuals experiencing moderate impairment, dropping from 26.7% to just 3.3%, with a corresponding 95% CI = [0.00 - 0.17]. Conclusion: The findings derived from this study illustrate an enhancement in the aspects of participants’ overall health and functional condition, including blood pressure, heart rate, and respiratory rate. Consequently, physiotherapy exercises can be employed as a tactic to ameliorate the functional status and physical well-being of older individuals afflicted with mental disorders in Zambia.

关键词： Elderly Mental Health Conditions Physiotherapy Exercise

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Acute bacterial sternoclavicular osteomyelitis in a long-term renal transplant recipient

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World Journal of Transplantation 2016年第2期6卷 442-446页

作者： Evangelia Dounousi anila duni Sofia Xiromeriti Charalambos Pappas Kostas C Siamopoulos Nephrology Department University Hospital of Ioannina

Kidney transplantation is the treatment of choice for a significant number of patients with end-stage renal disease. Although immunosuppression therapy improves graft and patient's survival, it is a major risk factor for infection following kidney transplantation altering clinical manifestations of the infectious diseases and complicating both the diagnosis and management of renal transplant recipients(RTRs). Existing literature is very limited regarding osteomyelitis in RTRs. Sternoclavicular osteomyelitis is rare and has been mainly reported after contiguous spread of infection or direct traumatic seeding of the bacteria. We present an interesting case of acute, bacterial sternoclavicular osteomyelitis in a long-term RTR. Blood cultures were positive for Streptococcus mitis, while the portal entry site was not identified. Magnetic resonance imaging of the sternoclavicluar region and a three-phase bone scan were positive for sternoclavicular osteomyelitis. Eventually, the patient was successfully treated with Daptomycin as monotherapy. In the presence of immunosuppression, the transplant physician should always remain alert for opportunistic pathogens or unusual location of osteomyelitis.

关键词： Bacterial infections Immunosuppression Renal transplantation Osteomyelitis

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A Universal BIST Approach for Virtex-Ultrascale Architecture

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Computer Systems Science & Engineering 2023年第6期45卷 2705-2720页

作者： N.Sathiabama S.anila CSI College of Engineering Ketti643215TamilnaduIndia Sri Ramakrishna Institute of Technology Coimbatore641010TamilnaduIndia

Interconnected cells,Configurable Logic Blocks(CLBs),and input/output(I/O)pads are all present in every Field Programmable Gate Array(FPGA)*** interconnects are formed by the physical paths for connecting the *** combinational and sequential circuits are used in the logic blocks to execute logical *** FPGA includes two different tests called interconnect testing and logical *** of using an additional circuitry,the Built-in-Self-Test(BIST)logic is coded into an FPGA,which is then reconfigured to perform its specific operation after the testing is *** a result,additional test circuits for the FPGA board are no longer *** FPGA BIST has no area overhead or performance reduction issues like conventional BIST.A resource-efficient testing scheme is essential to assure the appropriate operation of FPGA look-up tables for effectively testing the functional *** this work,the Configurable Logic Blocks(CLBs)of virtex-ultrascale FPGAs are tested using a BIST with a simple *** evaluate the CLBs’capabilities including distributed modes of operation of Random Access Memory(RAM),several types of configurations are *** setups have the ability to identify 100%stuck-at failures in every *** method is suitable for all phases of FPGA testing and has no overhead or performance cost.

关键词： Built-in-self-test TPG LUT ORA CLB FPGA testing

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Histological evolution of IgG4 related disease

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Rheumatology & Autoimmunity 2022年第4期2卷 244-246页

作者： Subrahmanian Sathiavageesan anila Abraham Department of Nephrology Sundaram HospitalTrichyTamilnaduIndia Global Clinical Research Scholar Training Harvard Medical SchoolBostonMassachusettsUSA Centre for Renal and Urological Pathology ChennaiTamilnaduIndia

To the Editor,IgG4‐related disease(IgG4‐RD)is a multisystem auto‐immune disorder with propensity to involve the *** clinical presentation,1 diagnostic classification criteria 2 and grading of disease activity(Responder Index)3 of IgG4‐RD have been well established,however there is scarce data on histological evolution of this disease entity ensuing immunosuppressive *** is a concern that the dense fibrotic lesions of IgG4‐RD could remain obstinate,notwithstanding immunosuppressive therapy,4 thereby leaving the affected organ with permanent *** present the case of a 57‐year‐old man with multi‐system IgG4‐RD in whom the dense lympho‐plasmocytic intersti-tial inflammation and the typical whorl‐like storiform fibrosis observed in initial kidney biopsy showed a near complete resolution following 4 months of immuno-suppressive therapy.

关键词： IgG4 kidney inflammation

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Synthesis and shape memory behavior study of hyperbranched poly(urethane-tetrazole)

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Science China Chemistry 2011年第9期54卷 1461-1467页

作者： QIAO LiGen ASIF anila SHI WenFang CAS Key Laboratory of Soft Matter Chemistry Department of Polymer Science and Engineering University of Science and Technology of China Hefei 230026 China Interdisciplinary Research Centre in Biomedical Materials COMSATS Institute of lnformation Technology Defence Road Off Raiwind Road Lahore 54000 Pakistan

A novel hyperbranched poly(urethane-tetrazole)(HPUTZ) was synthesized via the "A2+BB2' " approach using hexadiisocyanate(HDI) and 3-(bis-(2-hydroxyethyl)) aminopropyltetrazole(HAPTZ).The molecular structure was characterized by FTIR and 1H NMR *** number average molecular weight was measured to be 1.05×104 g/mol with a polydispersity of 1.27 by GPC *** HPUTZ was further cured by the semi-adduct(PEG-IPDI) from polyethylene glycol(PEG) reacting with isophorone diisocyanate(IPDI) to form the crosslinked HAPTZ-PU film in different ratio of HAPTZ to *** glass transition temperature of HAPTZ-PU increased from 44.9 to 56.4 ℃ as the HPUTZ content increased from 20% to 33% from the DSC *** DMA results indicated that the HPUTZ-PU with 20% HPUTZ possessed the highest storage modulus and loss ***,the storage modulus increased with the increasing of HPUTZ segment at higher *** shape memory study showed that all the films presented the excellent shape memory *** 98% shape recovery could be obtained for the HAPTZ-PU with 20%-33% HAPTZ segment content within 60 s in the tension deformation test and within 40 s at 80 ℃ in the bend deformation test.

关键词：形状记忆功能氨基甲酸乙酯四氮唑超支化行为研究合成玻璃化转变温度异佛尔酮二异氰酸酯

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One-Pot Aqueous Synthesis of Highly Biocompatible Near Infrared CulnS2 Quantum Dots for Target Cell Imaging

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Chinese Journal of Chemistry 2016年第6期34卷 576-582页

作者： anila Arshad Hongli Chen Xilin Bai Suying Xu Leyu Wang State Key Laboratory of Chemical Resource Engineering Beijing Key Laboratory of Environmentally Harmful Chemical Analysis Beijing University of Chemical Technology Beijing 100029 China

In this study, we report a novel and facile autoclave strategy for synthesis of near-infrared （NIR） CulnS2 QDs by employing glutathione （GSH） as capping ligand and stabilizer in aqueous media under 100 ~C. Various experi- mental parameters including the ratio of precursors, reaction time, reaction temperature, pH effect and stability have been systematically studied. The QDs were characterized by X-ray diffraction （XRD）, transmission electron micro- scope （TEM）, and Fourier transform infrared spectroscopy （FT-IR）. The as-synthesized NIR QDs exhibited low cytotoxicity and maintained excellent cell viability even up to 100 gg/mL. After bioconjugation with Arg-Gly-Asp （RGD） peptide, the obtained CulnS2-RGD QDs have demonstrated high targeting ability with good fluorescence cell imaging performance.

关键词： CulnS2 quantum dots hydrophilic synthesis photoluminescence cell imaging

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A visual photothermal paper sensor for H_2S recognition through rational modulation LSPR wavelength of plasmonics

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Science China Chemistry 2018年第3期61卷 368-374页

作者： Hui Wang Jiabin Cui anila Arshad Suying Xu Leyu Wang State Key Laboratory of Chemical Resource Engineering School of Science Beijing University of Chemical Technology

It is known that the localized surface plasmon resonance(LSPR) wavelength of plasmonics is highly dependent on compositions and geometry of plasmonics as well as the surrounding environments. Here, monodispersed Au@Ag core-shell nanoparticles(Au@Ag NPs) were prepared by carefully optimizing the shell thickness of Au@Ag NPs, and the presence of hydrogen sulfide(H_2 S) would significantly alter the LSPR wavelength. On the basis of this, a photothermal paper sensor for on-site recognition of H_2 S was constructed with a visual detection limit of 12.8 ng/L.

关键词：纸传感器合理调整波长视觉识别局部性几何学 NP

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Enhanced biocompatibility of ZnS:Mn quantum dots encapsulated with Aloe vera extract for therapeutic applications

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Chinese Physics B 2016年第8期25卷 412-416页

作者： Anilkumar M Bindu K R Sneha Saj A anila E I Cell Culture Laboratory Department of Botany UC College Optoelectronic and Nanomaterials' Research Laboratory Department of Physics UC College Department of Physics SSV College

Toxicity of nanoparticles remains to be a major issue in their application to the biomedical field. Aloe vera（AV） is one of the most widely exploited medicinal plants that have a multitude of amazing properties in the field of *** extract of Aloe vera can be used as a novel stabilising agent for quantum dots to reduce toxicity. We report the synthesis, structural characterization, antibacterial activity and cytotoxicity studies of ZnS：Mn quantum dots synthesized by the colloidal precipitation method, using methanol extract of Aloe vera（AVME） as the capping agent. The ZnS：Mn quantum dots capped with AVME exhibit superior performances in biocompatibility and antibacterial activity compared with ZnS：Mn quantum dots without encapsulation.

关键词： quantum dot transmission electron microscopy biocompatibility

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Catalase-imprinted Fe3O4/Fe@fibrous SiO2/polydopamine nanoparticles： An integrated nanoplatform of magnetic targeting, magnetic resonance imaging, and dual-mode cancer therapy

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Nano Research 2017年第7期10卷 2351-2363页

作者： Jinxing Chen Shan Lei Kun Zeng Mozhen Wang anila Asif Xuewu Ge CAS Key Laboratory of Soft Matter Chemistry Department of Polymer Science and Engineering University of Science and Technology of China Hefei 230016 China Interdisciplinary Research Centre in Biomedical Materials (IRCSM) COMSATS Institute of Information Technology Lahore 54000 Pakistan

Recent advances in the research on the molecular mechanism of cell death and methods for preparation of nanomaterials make the integration of various therapeutic approaches, targeting, and imaging modes into a single nanoscale complex a new trend for the development of future nanotherapeutics. Hence, a novel ellipsoidal composite nanoplatform composed of a magnetic Fe3O4/Fe nanorod core （-120 nm） enwrapped by a catalase （CAT）-imprinted fibrous SiO2/ polydopamine （F-SiO2/PDA） shell with thickness 70 nm was prepared in this work. In vitro experiments showed that the Fe3O4/Fe@F-SiO2/PDA nanoparticles can selectively inhibit the bioactivity of CAT in tumor cells by the molecular imprinting technique. As a result, the H2O2 level in tumor cells was elevated dramatically. At the same time, the Fe304FFe core released Fe ions to catalyze the conversion of H2O2 to ＊OH in tumor cells. Eventually, the concentration of ＊OH in tumor cells rapidly rose to a lethal level thus triggering apoptosis. Combined with the remarkable near-infrared light （NIR） photothermal effect of the CAT- imprinted PDA layer, the Fe3O4/Fe@F-SiO2/PDA nanoparticles can effectively kill MCF-7, HeLa, and 293T tumor cells but are not toxic to nontumor cells. Furthermore, these nanoparticles show good capacity for magnetic targeting and suitability for magnetic resonance imaging （MRI）. Therefore, the integrated multifunctional nanoplatform opens up new possibilities for high-efficiency visual targeted nonchemo therapy for cancer.

关键词： molecular imprintednanoparticles reactive oxygen species NIR photothermal therapy magnetic targeting magnetic resonanceimaging (MRI)

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