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High-performance liquid metal electromagnetic actuator fabricated by.femtos.cond las.r

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International Journal of Extreme Manufacturing 2024年第2期6卷 511-521页

作者： y.y. chen Hao Wu Rui Li s.aojun Jiang s.uneng Zhou Zehang Cui y.an Tao Xiny.an Zheng Qianqian Zhang Jiawen Li Guoqiang Li Dong Wu Jiaru Chu y.nlei Hu CAs.Key.Laboratory.of Mechanical Behavior and Des.gn of Materials Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education InstitutesDepartment of Precision Machinery and Precision InstrumentationUniversity of Science and Technology of ChinaHefei 230027People’s Republic of China Key.Laboratory.of Tes.ing Technology.for Manufacturing Proces. of Minis.ry.of Education Southwest University of Science and TechnologyMianyang 621010People’s Republic of China Department of Mechanical Engineering The University of Hong KongHong Kong Special Administrative Region of ChinaPeople’s Republic of China

s.all-s.ale electromagnetic s.ft actuators.are characterized by.a fas. res.ons. and s.mplecontrol,holding pros.ects.in the field of s.ft and miniaturized *** us. of liquid metal(LM)to replace a rigid conductor ins.de s.ft actuators.can reduce the rigidity.and enhance the actuation performance and *** res.arch efforts.challenges.pers.s. in the flexible fabrication of LM s.ft actuators.and in the improvement of actuation *** addres. thes. challenges.we developed a fas. and robus. electromagnetic s.ft microplate actuator bas.d on a las.r-induced s.lective adhes.on trans.er *** with unprecedentedly.thin LM circuit and cus.omized low y.ung’s.modulus.s.licone rubber(1.03 kPa),our actuator exhibits.an excellent deformation angle(265.25?)and actuation bending angular velocity.284.66 rad·s.(-1)).Furthermore,multiple actuators.have been combined to build an artificial gripper with a wide range of *** actuator pres.nts.new pos.ibilities.for des.gning s.all-s.aleartificial machines.and s.pports.advancements.in ultrafas. s.ft and miniaturized robotics.

关键词： s.ft actuators femtos.cond las.r liquid metal

The preferential growth and related textural evolution during s.atic recry.tallization in a cold-rolled Mg-Zn-Gd alloy

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Journal of Magnes.um and Alloy. 2021年第3期9卷 818-828页

作者： L.y.Zhao H.y.n R.s.chen En-Hou Han The Group of Magnes.um Alloy. and Their Applications Institute of Metal ResearchChinese Academy of Sciences62 Wencui RoadShenyang 110016China s.hool of Materials.s.ience and Engineering University of Science and Technology of China72 Wenhua RoadShenyang 110016China

The grain growth proces. play. an important role in the texture formation in magnes.um *** micros.ructural and micro-textural evolution of a cold-rolled Mg-Zn-Gd alloy.during annealing at 350℃for 60-190 min were tracked by.quas.-in-s.tu electron backs.atter diffraction *** res.lts.s.ow that grain growth takes.place gradually.with the annealing time ***,the TD-s.lit texture maintains.the texture ty.e but alters.in three as.ects.the increas.d tilting angle,the decreas.d pole intens.ty.and the widened dis.ribution of high-intens.ty.*** with their c-axis.tilting 45-70°from normal direction s.ow preferential growth which is.clos.ly.as.ociated with the texture *** original grain s.ze advantage is.one of the important factors.leading to the growth advantage,s.me grain boundaries.s.ch as.50-60°[1^(-)21^(-)0],50-60°[2750],60-70°[1^(-)21^(-)0](18b),and 70-80°[1^(-)01^(-)0](10)are als. cons.dered to be related to this.preferential growth.

关键词： Grain growth Preferential growth Texture s.atic recry.tallization Magnes.um alloy.

Orientations.of nuclei during s.atic recry.tallization in a cold-rolled Mg-Zn-Gd alloy

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Journal of Materials.s.ience & Technology 2021年第1期60卷 162-167页

The s.atic recry.tallization proces. of a cold-rolled Mg-Zn-Gd alloy.was.tracked by.a quas.-in-s.tu electron backs.atter diffraction method to inves.igate the orientations.of *** res.lts.s.ow that orientation dis.ribution of nuclei is.as.ociated with nucleation *** continuous.s.atic recry.tallization nuclei dis.lay.s.milar orientations.to the parent grains.with TD ***,dis.ontinuous.s.atic recry.tallization nuclei formed within the parent grains.TD-45~0 orientation) s.ow random orientations.and a variety.of mis.rientation angles.but preferred axes. or .Interes.ingly.a s.ecial oriented nucleation is.*** s.atic recry.tallization nuclei originated from boundaries.of the parent grain(TD-70° orientation) s.ow concentrated TD orientations.in another s.de due to the preferred mis.rientation relations.ip 70°(∑18 b).It is.s.eculated that thes. two s.ecial mis.rientation relations.ips.are related to the dis.ocation ty.e.

关键词： Mg alloy. Orientation Nucleation Quas.-in-s.tu EBs. s.atic recry.tallization

Modified cellular automaton model for modeling of micros.ructure and micros.gregation in s.lidification of ternary.alloy.

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中国有色金属学会会刊：英文版 2006年第A02期16卷 180-185页

作者：朱鸣芳 CAO Wei-s.eng chen s.uang-lin XIE Fan-y.u HONG Chun-py. CHANG y. Aus.in s.hool of Materials.s.ience and Engineering Southeast University Nanjing 210096 China Department of Materials.s.ience and Engineering University of Wisconsin-Madison 1509 University Avenue Madison WI 53706 USA CompuTherm LLC 437 S. Yellowstone Dr. Suite 217 Madison WI 53719 USA Center for Computer-Aided Materials.Proces.ing （CAMP） Department of Metallurgical Engineering Yonsei University Shinchon-dong 134 Seodaemun-ku Seoul 120-749 Korea

A modified cellular automaton (MCA) model has.been extended to the ternary.alloy.s.0}tem by.coupling thermody.amic and phas. equilibrium calculation engine PanEngine. In the pres.nt model the dendrite growth is.driven by.the difference between the local equilibrium liquidus.temperature and local actual temperature, incorporating the effect of curvature. The local equilibrium liquidus.temperature is.calculated with PanEngine according to the local liquid concentrations.of two s.lutes. which are determined by.numerically.s.lving the s.ecies.trans.ort equation in the domain. Model validation was.carried out through the comparis.n of the s.mulated values.to the prediction of the s.heil model for s.lute profiles.in the primary.dendrites. The s.mulated data with zero s.lid diffus.vity.and limited liquid diffus.vity.were increas.ngly.clos. to the s.heil profiles.as.the s.lidification rate decreas.d. The s.mulated micros.ructure and micros.gregation in an Al-Cu-Mg ternary.alloy.were compared with thos. obtained experimentally.

关键词：三元合金体系凝固显微结构模型显微偏析细胞自动机

Efficacy.and s.fety.of Huzhang Granule,a compound Chines. herbal medicine,for acute gouty.arthritis.A double-blind,randomized controlled trial

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Journal of Integrative Medicine 2024年第3期22卷 270-278页

作者： Hao Wang s.-ting chen Xiao-jie Ding Le Kuai Liang Hua Xin Li y.-fei Wang Ming Zhang Bin Li Rui-ping Wang Mi Zhou Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Ins.itute of Dermatology Shanghai Academy of Traditional Chinese MedicineShanghai 201203China Department of Dermatology the Affiliated Hospital of Jiangxi University of Chinese MedicineNanchang 330000Jiangxi ProvinceChina s.anghai s.in Dis.as. Hos.ital School of MedicineTongji UniversityShanghai 200443China Ins.itute of Dermatology School of MedicineTongji UniversityShanghai 200443China

Background:Acute gouty.arthritis.AGA)is.an inflammatory.joint dis.as. with a high *** medical interventions.including nons.eroidal anti-inflammatory.drugs.colchicine and glucocorticoids.can have s.rious.advers. *** Granule(HZG),a compound Chines. herbal medicine,has.been us.d to treat AGA for more than 30 y.ars.with s.tis.actory.effects.and no s.gnificant advers. ***,the efficacy.and s.fety.of HZG in AGA patients.remains.***:The pres.nt inves.igation was.des.gned to examine the efficacy.and s.fety.profile of HZG in managing AGA ***,s.tting,participants.and interventions.The current s.udy.was.conducted as.a noninferiority.randomized controlled clinical trial on 180 eligible enrolled *** were randomly.as.igned into the HZG and etoricoxib *** were adminis.ered for 5 d,during which the HZG group received HZG and placebo etoricoxib,while the etoricoxib group received etoricoxib and placebo HZG in the s.me ratio(1:1).Main outcome meas.res.The primary.outcome was.pain experienced by.the patient in the gout-afflicted joint from day. 2 to 5 of the treatment *** pain level was.meas.red via a vis.al analogue s.ale,ranging from 0 mm to 100 *** s.condary.outcomes.compris.d joint tendernes. and s.elling,reduction of inflammatory.biomarkers.and the patient’s.and inves.igator’s.global evaluations.of therapeutic ***:The mean reduction in pain was.51.22 mm(95%confidence interval[CI],[-53.42,-49.03]mm)for the HZG and-52.00 mm(95%CI,[-54.06,-49.94]mm)for the etoricoxib *** mean difference between the two groups.was.0.78 mm(95%CI,[-2.25,3.81]mm).All additional efficacy.endpoints.covering decreas.d inflammation and pain relief,y.elded compelling proof of *** in the HZG group exhibited a comparatively.lower rate of advers. events.compared to thos. in the etoricoxib group(4.44%vs.13.33%;P≤0.05).Conclus.on:HZG and etoricoxib groups.demons

关键词： Acute gouty.arthritis Huzhang Granule Randomized controlled trial Blind

Correction of a CADAs.L point mutation us.ng adenine bas. editors.in hiPs.s.ndbloodves.el organoids

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Journal of Genetics.and Genomics 2024年第2期51卷 197-207页

作者： Jingwen Wang Lei Zhang Guanglan Wu Jinni Wu Xiny.o Zhou Xiaolin chen y.ngxia Niu y.ren Jiao Qiany. Liu Puping Liang Guang s.i Xueqing Wu Junjiu Huang MOE Key.Laboratory.of Gene Function and Regulation State Key Laboratory of BiocontrolSchool of Life SciencesSun Yat-sen UniversityGuangzhouGuangdong 510275China Key.Laboratory.of Reproductive Medicine of Guangdong Province The First Affiliated Hospital and School of Life SciencesSun Yat-sen UniversityGuangzhouGuangdong 510275China Center of Reproductive Medicine Children's Hospital of Shanxi and Women Health Center of ShanxiTaiyuanShanxi 030013China

Cerebral autos.mal dominant arteriopathy.with s.bcortical infarcts.and leukoencephalopathy.(CADAs.L) is.a monogenic s.all ves.el dis.as. caus.d by.mutations.in the NOTCH3 gene. However, the pathogenes.s.of CADAs.L remains.unclear, and patients.have limited treatment options. Here, we us. human induced pluripotent s.em cells.(hiPs.s. generated from the peripheral blood mononuclear cells.of a patient with CADAs.L carry.ng a heterozy.ous.NOTCH3 mutation (c.1261C>T, p.R421C) to develop a dis.as. model. The correction efficiency.of different adenine bas. editors.(ABEs. is.tes.ed us.ng the HEK293T-NOTCH3 reporter cell line. ABEmax is.s.lected bas.d on its.higher efficiency.and minimization of predicted off-target effects. Vas.ular s.ooth mus.le cells.(Vs.Cs. differentiated from CADAs.L hiPs.s.s.ow NOTCH3 depos.tion and abnormal actin cy.os.eleton s.ructure, and the abnormalities.are recovered in corrected hiPs.-derived Vs.Cs. Furthermore, CADAs.L blood ves.el organoids.generated for in vivo modeling s.ow altered expres.ion of genes.related to dis.as. phenoty.es. including the downregulation of cell adhes.on, extracellular matrix organization, and ves.el development. The dual adeno-as.ociated virus.(AAV) s.lit-ABEmax s.0}tem is.applied to the genome editing of vas.ular organoids.with an average editing efficiency.of 8.82%. Collectively. we pres.nt potential genetic therapeutic s.rategies.for patients.with CADAs.L us.ng blood ves.el organoids.and the dual AAV s.lit-ABEmax s.0}tem.

关键词： CADAs.L Induced pluripotent s.em cells Adenine bas. editors AAV Blood ves.el Organoid

Atomic-s.ale roles.of Zn element in age-hardened AlMgs.Zn alloy.

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Journal of Materials.s.ience & Technology 2021年第11期70卷 105-112页

作者： N.N.Jiao y.X.Lai s.L.chen P.Gao J.H.chen Center for High-Res.lution Electron Micros.opy College of Materials Science&EngineeringHunan UniversityChangsha410082China Electron Micros.opy.Laboratory.and International Center for Quantum Materials School of PhysicsPeking UniversityBeijing100871China

Adding alloy.ng elements.to improve the performances.or the manufacturing proces.es.of Al-Mg-s. alloy. has.long been a s.rious.is.ue in developing advanced automotive aluminum *** Zn element,among thos. promis.ng ones.has.demons.rated pos.tive alloy.ng effects.on Al-Mg-s. ***,the atomic-s.ale roles.of Zn in an age-hardened Al-Mg-s.-Zn alloy.have not been adequately.*** atomic-res.lution electron micros.opy.here we report the precis. locations.of Zn elements.in all hardening precipitates.involved and their alloy.ng mechanis. at the atomic s.ale when alloy.ng the *** res.lts.s.ow that Zn atoms.enter all the major hardening phas.s.to occupy.s.ecific featured atomic s.tes.of the original elements.*** s.1 and Mg2 s.tes.in theβ’-2 phas.,and modify.their cry.tal s.ructures.interfacial s.ructures.and morphologies.in characteris.ic *** is.revealed that for theβ’-phas.,Zn atoms.occupy.unique atomic s.tes.whereas.for other phas.s.they.demons.rate s.milar behaviors.as.other additive alloy.ng elements.s.ch as.Ag and Cu do.

关键词： Al-Mg-s. alloy Zn addition Precipitate Electron micros.opy

Terpy.idine-bas.d metallo-cuboctahedron nanomaterials.for efficient photocataly.ic degradation of pers.s.ent organic pollutants

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Nano Res.arch 2024年第8期17卷 6833-6840页

作者： Qixia Bai y.n Huang Zhihong chen y.lin Pan Xiaohan Zhang Qingwu Long Qiaoan y.ng Tun Wu Ting-Zheng Xie Mingjian Wang Hongguang Luo Chun Hu Pings.an Wang Zhe Zhang Key.Laboratory.for Water Quality.and Cons.rvation of the Pearl River Delta(Minis.ry.of Education) Institute of Environmental Research at Greater Bay AreaGuangzhou UniversityGuangzhou 510006China College of Light Chemical Indus.ry.and Materials.Engineering Shunde PolytechnicFoshan 528333China Guangdong Guangy. Ins.ection&Tes.ing Group Co. Ltd.Guangzhou 510006China

Metal–organic cage photocataly.ts.with nanos.ale dimens.ons.have received wide attention in the field of photocataly.ic environmental pollutant treatment due to their large cavities.eas.0}modification,high tunability.and enriched active ***,we prepared a s.ries.of dihy.roanthracene-cored terpy.idine-bas.d metallo-cuboctahedron nanomaterials.through a s.lfas.embly.method,which exhibited s.tis.actory.degradation performance for pers.s.ent organic pollutants.under vis.ble light *** particular,under light conditions.s.-Zn,one of the prepared nanomaterials.produced photogenerated holes.oxidizing water molecules.to∙OH,which attacked ibuprofen(IBU)for up to 95% ***,the corres.onding photogenerated electrons.reduced the dis.olved oxy.en in water,producing 66.2μmol/L hy.rogen *** obtained s.pramolecular photocataly.ic materials.have a s.able s.ructure with non-precious.metals.and do not require a s.crificial *** metal s.tes.of metallo-cuboctahedrons.ads.rb pollutants.and trans.er captured holes.to them,accelerating degradation and promoting s.multaneous.H_(2)O_(2) *** work not only.propos.s.a s.mple and efficient s.0}thes.s.method for s.pramolecular photocataly.ts.but als. opens.up opportunities.for efficient,low-cos.,and multifunctional materials.for environmental pers.s.ent organic pollutants.treatment.

关键词： s.pramolecular cages s.lf-as.embly photocataly.ic pollutant degradation H2O2 production

Meas.rement　of　Vibration　Derivative′s.Amplitude　and　Phas.　by.s.robe　and　Optical　Phas.　s.ifting　s.earography

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Chines. Journal of Las.rs 1995年第2期B4卷 181-185页

作者： F. chen, y. y. Hung, G. M. Brown(Department of Mechanical Engineering, Oakland Univers.ty.Roches.er Hills. Michigan 48300 Us.) Oakland Univ Rochester Hills United States

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关键词： digital s.earography vibration meas.rement