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Insect Science 2015年第1期22卷 139-149页

作者： Benjamin Ferstenau Carmen Quero Josep Ma Riba Gloria Rosell angel guerrero Department of Biological Chemistry and Molecular Modelfing IQAC (CSIC) Jordi Girona 18-26 08034 Barcelona Department of AnimalBiology Faculty of Biology University of Barcelona Avda. Diagonal 643 08028 Barcelona Department of Pharmacology andTherapeutic Chemistry (Associated to CSIC) Faculty of Pharmacy University of Barcelona Joan XXIII 27-31 08028 Barcelona Spain

The flathead oak borer Coroebus undatus E （Coleoptera： Buprestidae） is one of the primary pests of cork oak Quercus suber L. in the Mediterranean region causing great economic losses to the cork industry. Very little is known about its biology and behavior and, so far, no control measures have been established. We present the results of a pilot study aimed to develop an efficient trapping method for monitoring this harmful pest. In a 3-year field study, purple-colored prism traps baited with a mixture of green leaf volatiles （GLVs） from the host have been shown the most effective combination to catch C. undatus adults （solely females） compared to other trap and lure types tested. Wavelength and reflectance measurements revealed that purple traps exhibit reflectance peak values similar to those found in the abdominal and elytral cuticle of both sexes, suggesting the involvement of visual cues for mate location in this species. The data presented are the first to demonstrate captures of adults of the genus Coroebus by an attractant-based trapping method.

关键词： attractants Buprestidae Coroebus undatus green leafvolatiles monitoring Quercus suber

Comparison between type-2 and type-1 myocardial infarction：clinical features, treatment strategies and outcomes

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Journal of Geriatric Cardiology 2016年第1期13卷 15-22页

作者： angel Lopez-Cuenca Miriam Gomez-Molina Pedro J Flores-Blanco Marianela Sanchez-Martinez Andrea Garcia-Narbon Ignacio De Las Heras-Gomez Maria J Sainchez-Galian Esther guerrero-Perez Mariano Valdes Sergio Manzano-Femandez Department of Internal Medicine Hospital de la Vega Lorenzo Guirao Cieza Spain Division of Cardiology University Hospital Virgen de la Arrixaca School of Medicine IMIB Murcia Spain Department of Biochemistry University Hospital Virgen de la Arrixaca School of Medicine IMIB Murcia Spain Department of lnternal Medicine University of Murcia Murcia Spain

Objective To assess the differences in incidence, clinical features, current treatment strategies and outcome in patients with type-2vs. type-1 acute myocardial infarction （AMI）.Methods We included 824 consecutive patients with a diagnosis of type-1 or type-2 AMI. Dur-ing index hospitalization, clinical features and treatment strategies were collected in detail. At 1-year follow-up, mortality, stroke, non-fatal myocardial infarction and major bleeding were ***-1 AMI was present in 707 （86%） of the cases while 117 （14%） were classified as type-2. Patients with type-2 AMI were more frequently female and had higher co-morbidities such as diabetes, previous non-ST segment elevation acute coronary syndromes, impaired renal function, anaemia, atrial fibrillation and malignancy. However, preserved left ventricular ejection fraction and normal coronary arteries were more frequently seen, an invasive treatment was less common, and anti-platelet medications, statins and beta-blockers were less prescribed in patients with type-2 AMI. At 1-year follow-up, type-2 AMI was associated with a higher crude mortality risk （HR： 1.75, 95% CI： 1.14-2.68;P = 0.001）, but this association did not remain significant after multivariable adjustment （P = 0.785）. Furthermore, we did not find type-2 AMI to be associated with other clinical *** In this real-life population, compared with type-1, type-2 AMI were predominantly women and had more co-morbidities. Invasive treatment strategies and cardioprotective medications were less used in type-2, while the 1-year clinical outcomes were similar.

关键词： Coronary vessels Follow-up studies Myocardial infarction

Clinical Parameters of Metabolic Control (HbA_(1c)) and Deterioration of Peripheral Arterial Perfusion in Type 2 Diabetes

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Journal of Diabetes Mellitus 2017年第1期7卷 31-39页

作者： Made Lourdes Zuniga-Martinez Yolanda Teran-Figueroa Laura Escarlet guerrero-Cruz angel Antonio Vertiz-Hernandez Academic Coordination Altiplano Region Autonomous University of San Luis PotosiSan Luis PotosiMexico Faculty of Nursing and Nutrition Autonomous University of San Luis PotosiSan Luis PotosiMexico

Objective: To determine the relationship between clinical parameters (HbA1c) whit metabolic control and deterioration of peripheral arterial perfusion in diabetic patients. Methodology: 108 medical records of patients with type 2 diabetes mellitus were evaluated. We obtained averages of: blood glucose (162.3 ± 73.10 mg/dl), glycated hemoglobin (HbA1c = 7.64% ± 1.77%), cholesterol (189.28 ± 35.25 mg/dl), triglycerides (189.11 ± 87.76 mg/dl), Systolic Blood Pressure (SBP = 119.69 ± 14.95 mmHg), Diastolic Blood Pressure (DBP = 77.15 ± 9.55 mmHg) and Media Blood Pressure (MBP = 91.36 ± 9.89 mmHg). We correlated variable HbA1c with vascular injury symptomatology. Results: Correlation was found between sensitivity dysfunction and HbA1c with a statistical significance of p = 0.01, and a correlation Kendal coefficient w = 0.01, any other parameter of metabolic control was not correlated with symptoms of vascular injury. Conclusion: It is remarkable that the sensitivity dysfunction is a symptom of poorly vascularized lower extremities caused for both functional impairment and structural changes in diabetic patients’ peripheral nerves, even in the preclinical stage of vascular disease. The HbA1c could also be investigated as a likely sensitivity dysfunction biomarker in DM due to the correlation presented in this study but more studies must be realized.

关键词： Protein Glycation Vascular Disease HbA_(1c) Type 2 Diabetes Mellitus

Antinociceptive and Anti-inflammatory Activities of Methanol Extract of Ormosia coccinea （Aubl,） Jacks in vivo

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Journal of Pharmacy and Pharmacology 2017年第6期5卷 289-298页

作者： Miguel angel Diaz C. Lorena H. Cruz M. Mahabir P. Gupta Dionisio Olmedo Jose Luis Lopez-Perez Estela guerrero De Leon Juan Antonio Moran-Pinzon Direccidn Nacional de Farmacia y Drogas Ministerio de Salud Panama Apartado 06812-0816 Republica de Panama Centro de lnvestigaciones Farmacognosticas de la Flora Panamena (CIFLORPAN) Facultad de Farmacia Universidad de Panama Panama Apartado 0824-00172 Republica de Panama Departamento de Quimica FarmacOutica Facultad de Farmacia Universidad de Salamanca Salamanca Apartado 37007 Spain Departamento de Farmacologla Facultad de Medicina Universidad de Panama Panama Apartado 0824 Panama

The present study was conducted to evaluate the antinociceptive and anti-inflammatory activities of methanol extract of rachis of Ormosia coccinea （Aubl.） Jacks （MEOC） using animal models of nociception and inflammation. The antinociceptive activity of the extract was assessed using acetic acid-induced abdominal writhing, hot-plate, and formalin tests. Oral administration of MEOC （500 mg/kg） produced significant （t7 〈 0.05） antinociceptive effects when tested in mice using acetic acid-induced abdominal writhing test and on the inflammatory phase of the formalin test. It was also demonstrated that MEOC had no significant effect on the response latency time to the heat stimulus in the thermal model of the hot plate test. The anti-inflammatory activity of the extract was assessed using carrageenan, histamine and serotonin induced oedema in rat paw. The oral administration of MEOC showed maximum inhibition （64.29%） at 1 h on carrageenan edema, but it did not modify the edema induced by histamine and serotonin. The present results suggest that MEOC has a peripheral antinoeiceptive and anti-inflammatory action.

关键词： Ormosia coccinea antinociceptive anti-inflammatory fabaceae.

Interferon Regulatory Factor 5 and Renin-Angiotensin-Aldosterone System Polymorphisms in Coronary Artery Disease: An Overview of Experimental and Clinical Studies

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World Journal of Cardiovascular Diseases 2021年第7期11卷 332-341页

作者： Jorge Luis Bermudez-Gonzalez Rodrigo Dagio-Cuellar Cristina Villarreal-guerrero Ana Gilabert-Garcia Luis angel Ferral-Barbabosa Joaquin Berarducci Jose Luis Siller-Nava Jose Antonio Luna-Alvarez-Amezquita Javier Iván Armenta-Moreno Nilda Espínola-Zavaleta Erick Alexanderson-Rosas Juan Ignacio Straface National Institute of Cardiology Ignacio Chavez Mexico City Mexico Medicine Faculty of National Autonomous University of Mexico Mexico City Mexico

Heart diseases are the main cause of mortality in Mexico, being coronary heart disease the most frequent in the country. Its high prevalence makes important the study of the pathophysiology and the search for prognostic factors. Different genes and polymorphisms promote atherogenesis and coronary artery disease, they affect inflammatory and vascular pathological processes. Interferon regulatory factor 5 (IRF5) is associated with coronary heart disease, it promotes chronic inflammation and cytokines release;it could trigger immune reactions and its activating receptors express in the vascular endothelium. Besides, polymorphisms in the renin-angiotensin-aldosterone system (RAAS) are implied with coronary disease, they are found in angiotensinogen (AGT), angiotensin II type 1 receptor (AT1R), angiotensin II type 2 receptor (AT2R), and angiotensin-converting enzyme (ACE) genes. These genetic polymorphisms are associated with a prothrombotic state, endothelial dysfunction, and immune activation. Multiple experimental studies showed that chronic activation of RAAS and chronic expression of IRF5 generates an environment prone to the development of atherosclerosis, and autoimmune and cardiovascular diseases. Studying these specific genes and their relationship with coronary heart disease will allow a better understanding of the pathological process and possibly the quest for new treatments.

关键词： Interferon Regulatory Factor 5 (IRF5) Angiotensin-Converting Enzyme (ACE) Angiotensinogen (AGT) Angiotensin II Type 1 Receptor (AT1R) Angiotensin II Type 2 Receptor (AT2R) Polymorphisms

Histological Analysis and Morphometric Changes after Autologous Fat Grafting in Large Volumes on Pigs

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Journal of Cosmetics, Dermatological Sciences and Applications 2021年第4期11卷 371-380页

作者： Hector Giancarlo Torres-Nuño Walter angel Trujillo-Rangel Jorge Barrera-Alcocer Miriam Méndez del Villar Diana Mercedes Hernández-Corona Sylvia Elena Totsuka-Sutto Leonel García Benavides Institute of Therapeutics and Clinical Experimentation Department of Physiology Health Sciences University Center (CUCS) University of Guadalajara (UDG) Guadalajara Mexico Obesity and Diabetes Research Laboratory Faculty of Chemistry and Biological Sciences Autonomous University of Guerrero (UAGro) Chilpancingo Mexico Multidisciplinary Health Research Center Biomedical Sciences Department Tonala University Center (CUT) University of Guadalajara (UDG) Guadalajara Mexico

Nowadays, fat transfer is an accepted technique that has been popularized in clinical practice, during which large volumes of fat are strategically relocated to increase and improve the contour of the body. In the present study, we investigated the histological and morphometric changes after large volumes of fat were grafted within the subcutaneous cellular tissue. An experimental study was designed using four 3-month-old male pigs. One hundred cc of decanted fat tissue was transferred into the right leg. Volume augmentation achieved by auto lipo-injecting within the subcutaneous cellular tissue persisted up to two months. Although there is a reduction in cell number and size, an increased amount of extracellular matrix and the presence of oily cysts and microcalcifications were observed. Conclusion: The volume augmentation, which is achieved by autologous fat transfer in large quantities in subcutaneous cellular tissue, can remain for months.

关键词： Autologous Fat Transfer Adipose Tissue Transplant Autologous Fat Injection Gluteal Augmentation