检索结果-南通市图书馆

计算机应用文摘 2018年第1期34卷 32-33页

作者：方浩 ane

在刚刚落幕的高通骁龙技术峰会上，一句“Always Connected PC”，宣告高通瞄准了PC市场，并声称这场PC的革命才刚刚开始。业界不禁会问，从智能手机NPC，高通的野心能如愿实现吗？

关键词： PC市场高通愿望智能手机 NPC 瞄准

短暂性脱髓鞘导致长期认知障碍、髓鞘改变和神经网络同步缺陷

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

神经损伤与功能重建 2024年第3期19卷 F0003-F0003页

作者： Océane Mercier Pascale P Quilichini Karine Magalon Florian Gil Antoine ghestem Fabrice Richard Thomas Boudier Myriam Cayre Pascale Durbec 杜一星(编译) UMR7288 after IBDM Aix Marseille UnivCNRSIBDMMarseilleFrance U1106 after INS Aix Marseille UnivINSERMINSInst Neurosci SystMarseilleFrance Aix Marseille Univ Turing Centre for Living SystemsMarseilleFrance 不详

在成年大脑中,活动依赖性髓鞘可塑性是正确学习和记忆巩固所必需的。因此,髓鞘的丢失、改变,甚至细微的结构变更都会损害神经网络活动,导致功能障碍。在多发性硬化症中,虽然自发的髓鞘修复过程是可能的,但患者之间存在异质性。髓鞘修复... 详细信息

在成年大脑中,活动依赖性髓鞘可塑性是正确学习和记忆巩固所必需的。因此,髓鞘的丢失、改变,甚至细微的结构变更都会损害神经网络活动,导致功能障碍。在多发性硬化症中,虽然自发的髓鞘修复过程是可能的,但患者之间存在异质性。髓鞘修复有时会导致功能恢复,这通常在运动水平比在认知水平更明显。在铜宗处理的小鼠模型中,大量脑脱髓鞘随后发生自发且强烈的髓鞘再生。然而,重组髓鞘虽然具有功能,但可能不会表现出与发育髓鞘相同的形态特征,这可能会对神经网络的活动产生影响。基于此,本研究使用铜腙处理的小鼠模型来分析短暂性脱髓鞘对脑结构、功能和认知的长期影响。本研究结果表明,尽管脱鞘事件后存在髓鞘再生,但仍会导致长期认知障碍,例如空间工作记忆、社交记忆、认知灵活性和多动症的缺陷。这些缺陷与内侧前额叶皮质(m PFC)和海马体(hPC)髓鞘含量的减少以及结构髓鞘修饰有关,表明这些结构中的髓鞘再生过程可能不完善。在体电生理记录表明,脱髓鞘事件改变了hPC-mPFC活动的同步性,这对于记忆过程至关重要。总而言之,本研究数据表明,短暂脱髓鞘后的髓鞘修复过程不允许完全恢复皮质结构中的初始髓鞘特性。这些细微的变更改变了神经网络特征并导致小鼠长期认知缺陷。

关键词：认知多发性硬化症小鼠模型髓鞘再生神经网络活动

Optical Coherence Tomography Findings in a Case of Unilateral Acute Idiopathic Maculopathy

在线全文

学校读者我要写书评

暂无评论

Open Journal of Ophthalmology 2012年第4期2卷 119-121页

作者： José Andonegui José Ramón Maya ane Zurutuza Mónica Pérez de Arcelus Ophthalmology Department Complejo Hospitalario de Navarra Pamplona Spain

Purpose: To describe the clinical, angiographic, and Optical Coherence Tomography (OCT) findings in a patient with Unilateral Acute Idiopathic Maculopathy (UAIM) and to discuss a possible pattern of OCT findings in patients with this disease. Methods: Case report. Results: A 34-year-old man with UAIM was evaluated. During the acute phase fundus examination revealed a yellow thickening in the macular area of the right eye, Fluorescein Angiography (FA) showed early alternating patches of hypofluorescence and hyperfluorescence and late hyperfluorescence and OCT showed thickening of the outer retina in the foveal zone. Six weeks later, the macula had pigmentary mottling, FA showed an area of central hypofluorescence surrounded by a hyperfluorescent ring that remained unchanged during the angiogram and the OCT examination was normal. Conclusion: OCT is a useful diagnostic tool for UAIM. OCT evaluation of patients with this disease will exhibit the heterogeneous hyperreflectivity and thickening of the outer retina and Retinal Pigment Epithelium (RPE). A serous macular detachment may not be a prominent finding in UAIM.

关键词： Unilateral Acute Idiopathic Maculopathy Optical Coherence Tomography

Allocation of patients with liver cirrhosis and organ failure to intensive care: Systematic review and a proposal for clinical practice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第29期21卷 8964-8973页

作者： Katrine Prier Lindvig ane Sogaard Teisner Jens Kjeldsen Thomas Strom Palle Toft Valentin Furhmann Aleksander Krag Department of Gastroenterology and hepatology Odense University Hospital Department of anestesiology and Intensive Care Odense University Hospital Department of Intensive Care Medicine University Medical Center Hamburg-Eppendorf

AIM: To propose an allocation system of patients with liver cirrhosis to intensive care unit(ICU), and developed a decision tool for clinical practice. METhODS: A systematic review of the literature was performed in Pub Med, MEDLINE and EMBASE databases. The search includes studies on hospitalized patients with cirrhosis and organ failure, or acute on chronic liver failure and/or intensive care therapy. RESULTS: The initial search identified 660 potentially relevant articles. Ultimately, five articles were selected; two cohort studies and three reviews were found eligible. The literature on this topic is scarce and no studies specifically address allocation of patients with liver cirrhosis to ICU. Throughout the literature, there is consensus that selection criteria for ICU admission should be developed and validated for this group of patients and multidisciplinary approach is mandatory. Based on current available data we developed an algorithm, to determine if a patient is candidate to intensive care if needed, based on three scoring systems: premorbid Child-Pugh Score, Model of End stage Liver Disease score and the liver specific Sequential Organ Failure Assessment ***: There are no established systems for allocation of patients with liver cirrhosis to the ICU and no evidence-based recommendations can be made.

关键词： Cirrhosis Failure Intensive care Allocation Treatment

The Storm Tracks Response to Changes in Atmospheric Greenhouse Gas Concentration at the South of Brazil and Southwest Atlantic Ocean

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atmospheric and Climate Sciences 2019年第4期9卷 545-557页

作者： Rose ane Pereira De Freitas Fernanda Casagrande Douglas Da Silva Lindemann Maria Angélica Gonçalves Cardoso Jeferson Prietsch Machado Forecasting and Meteorological Research Center Federal University of Pelotas(UFPEL)PelotasBrazil Earth System Science Centre(CCST-INPE) National Institute for Space Research(INPE)Sao Jose dos CamposBrazil Federal University of Santa Maria(UFSM) Santa MariaBrazil Oceanography Institute Federal University of Rio Grande(FURG)Rio GrandeBrazil

here we investigate the ocean-atmosphere coupling and the contribution of the Sea Surface Temperature (SST) variations in: 1) Brazil-Malvinas Confluence (BMC) region, 2) Southwest Atlantic Ocean and 3) Southern Brazil. Numerical simulations of the EChAM5/MPI-OM coupled ocean-atmosphere model were used to analyze the changes in the seasonal trajectory of the extratropical cyclones, in terms of intensification of physical mechanisms and implications for future scenarios. The numerical experiment for the future scenario considered an atmospheric CO2 concentration of approximately 770 ppm, which represents an increment of more than 350 ppm over the current values recorded by the Mauna Loa reference station. For this scenario, the results indicated a Storm Tracks (ST) displacement of 5° latitude toward south and changes of the meridional transport of sensible heat, close to 50°S. The increase in SST induces ST intensification and consequently an increase in the occurrence of extratropical cyclones. Overall, in the BMC region, we found a change in the pattern of cyclogenetic activity occurrence, with less frequent, but more intense events. On the Southern Brazilian region, the results of this study indicate increases in rainfall during summer months, whereas, a decrease in frequency and an increase in intensity were found for wintertime. We suggest that these changes could impact the climate dynamic of the Brazilian South coast, with a magnitude yet unknown.

关键词： Storm Tracks Confluence Brazil-Malvinas Atlantic Ocean

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

计算机模拟在化学理论与实验教学中的应用

大学化学 2016年第10期31卷 23-28页

作者：康明亮韩东梅 GEWIRTZ Océane 中山大学中法核工程与技术学院广东珠海519082

借助PhREEQC程序,探讨了计算机模拟在化学理论与实验教学中的应用。对于水溶液中的酸碱中和、络合反应、沉淀溶解平衡以及化学动力学等化学过程,建立了相应的反应模型。应用这些模型进行教学,促进了学生对所学知识的理解与掌握,提高了... 详细信息

借助PhREEQC程序,探讨了计算机模拟在化学理论与实验教学中的应用。对于水溶液中的酸碱中和、络合反应、沉淀溶解平衡以及化学动力学等化学过程,建立了相应的反应模型。应用这些模型进行教学,促进了学生对所学知识的理解与掌握,提高了教学质量,丰富了现代教学方法,为培养学生的创新实践能力及建立科学有效的研究方法打下了良好基础。

关键词：多媒体教学化学模拟 PhREEQC程序现代教学方法

TRANSLATING ThE MULTI-ACTOR APPROACh TO RESEARCh INTO PRACTICE USING A WORKShOP APPROACh FOCUSING ON SPECIES MIXTURES

在线全文

学校读者我要写书评

暂无评论

Frontiers of Agricultural Science and Engineering 2021年第3期8卷 460-473页

作者： henrik hAUGGAARD-NIELSEN Søren LUND ane K.AARE Christine A.WATSON Laurent BEDOUSSAC Jean-Noel AUBERTOT Iman R.ChONGThAM Natalia BELLOSTAS Cairistiona F.E.TOPP Pierre hOhMANN Erik S.JENSEN Maureen STADEL Bertrand PINEL Eric JUSTES Department of People and Technology Roskilde UniversityDK-4000 RoskildeDenmark Scotland’s Rural College(SRUC) AberdeenScotlandUnited Kingdom AGIR Univ ToulouseENSFEAINRAECastanet-TolosanFrance AGIR Univ ToulouseINRAECastanet-TolosanFrance Department of Biosystems and Technology Swedish University of Agricultural SciencesSE-23053 AlnarpSweden Instituto Navarro de Tecnologias e Infraestructuras Agroalimentarias(INTIA) 31610 VILLAVA(NAVARRA)Spain SRUC EdinburghScotlandUnited Kingdom Department of Crop Sciences Research Institute of Organic Agriculture(FiBL)CH-5070 FrickSwitzerland TERRENA AncenisFrance CIRAD Persyst DepartmentMontpellierFrance

The EIP-Agri multiactor approach was exemplified during a 3-day workshop with 63 project participants from the EU h2020 funded project“Redesigning European cropping systems based on species MIXtures”.The objective was to share firsthand experience of participatory research among researchers who were mostly not familiar with this *** participants were divided into smaller multidisciplinary groups and given the opportunity to interact with representatives from eight actor positions in the value chain of the agrifood cooperative Terrena located in Western *** four stages of the workshop were:(1)key actor interviews,(2)sharing proposed solutions for overcoming barriers,and(3)developing possible interdisciplinary *** of frustration were recorded serving both as a motivation for group members to become more aware of the scientific concerns and practices of their colleagues,as well as a recognition that some researchers have better skills integrating qualitative approaches than ***,the workshop format was an effective way to gain a common understanding of the pertinent issues that need to be addressed to meet overall multiactorapproach *** with the actor networks was identified and emphasized as a means to overcome existing barriers between academia and practice in order to coproduce a shared vision of the benefits of species mixture benefits.

关键词： agroecology codesign intercropping knowledge sharing participatory methods

在线全文

学校读者我要写书评

暂无评论

弹性地基上锥壳的精确解及应用

土木工程学报 1991年第4期24卷 74-86页

作者：黄义郭仁俊西安冶金建筑学院西安矿业学院

弹性地基上锥壳的弯曲问题,尤其是它的精确解,至今尚未解决。因此获得这一结构的求解方法,对理论和工程实际都具有重要意义。本文对弹性地基上锥壳进行系统分析,提出了轴对称弯曲的位移求解方法,求出了数值结果。同时,计算了一些柔度... 详细信息

弹性地基上锥壳的弯曲问题,尤其是它的精确解,至今尚未解决。因此获得这一结构的求解方法,对理论和工程实际都具有重要意义。本文对弹性地基上锥壳进行系统分析,提出了轴对称弯曲的位移求解方法,求出了数值结果。同时,计算了一些柔度系数表,可方便地用于弹性地基上锥壳的组合结构分析。此外,作为本文的应用实例,还对储液罐作了计算。

关键词：弹性地基锥壳弯曲储液罐

Multi-scale phylogenetic structure in coastal dune plant communities across the globe

在线全文

学校读者我要写书评

暂无评论

Journal of Plant Ecology 2014年第2期7卷 101-114页

作者： ane Kirstine Brunbjerg Jeannine Cavender-Bares Wolf L.Eiserhardt Rasmus Ejrnæs Lonnie W.Aarssen hannah L.Buckley Estelle Forey Florian Jansen Jens Kattge Cynthia Lane Roy A.Lubke Angela T.Moles Ana Laura Monserrat Robert K.Peet Julissa Roncal Louise Wootton Jens-Christian Svenning Ecoinformatics&Biodiversity Group Department of BioscienceAarhus UniversityNy Munkegade 114DK-8000 Aarhus C.Denmark Department of Bioscience Aarhus UniversityGrenaavej 14DK-8410 RøndeDenmark Department of Ecology Evolution and BehaviorUniversity of Minnesota1987 Upper Buford CircleFalcon HeightsMN 55108USA Department of Biology Queens University116 Barrie StreetKingstonOntario K7L 3N6Canada Department of Ecology Lincoln UniversityPO Box 84Canterbury 7647New Zealand Laboratoire d’Ecologie EA 1293 ECODIVFED SCALEUFR Sciences et TechniquesUniversitéde Rouen76821 Mont Saint Aignan CedexFrance Institute of Botany and Landscape Ecology Soldmannstr.1517487 GreifswaldGermany Functional Biogeography Research Group Max Planck Institute for BiogeochemistryHans Knoell Str.1007745 JenaThuringiaGermany Lake Lily Ecology Ltd.PO Box 8455CanmoreAB T1W 2V2Canada Department of Botany Rhodes UniversityPO Box 94GrahamstownEast Cape 6140South Africa Evolution&Ecology Research Centre School of BiologicalEarth and Environmental SciencesThe University of New South WalesBotany RoadKensingtonSydneyNew South Wales 2034Australia Grupo de Investigación en Sistemas Ambientales Complejos Facultad de IngenieríaUniversidad de FloresPedernera 275Ciudad de Buenos AiresArgentina Department of Biology University of North CarolinaChapel HillNC 27599-3280USA Department of Biology Memorial University of Newfoundland232 Elizabeth AvenueSt.John'sNL A1B 3X9Canada Department of Biology Georgian Court University900 Lakewood AvenueLakewoodNJ 08701USA

Aims Studies integrating phylogenetic history and large-scale community assembly are few,and many questions remain ***,we use a global coastal dune plant data set to uncover the important factors in community assembly across scales from the local filtering processes to the global long-term diversification and dispersal *** dune plant communities occur worldwide under a wide range of climatic and geologic conditions as well as in all biogeographic ***,global patterns in the phylogenetic composition of coastal dune plant communities have not previously been *** The data set comprised vegetation data from 18463 plots in New Zealand,South Africa,South America,North America and *** phylogenetic tree comprised 2241 plant species from 149 *** calculated phylogenetic clustering(Net Relatedness Index,NRI,and Nearest Taxon Index,NTI)of regional dune floras to estimate the amount of in situ diversification relative to the global dune species pool and evaluated the relative importance of land and climate barriers for these diversification patterns by geographic analyses of phylogenetic *** then tested whether dune plant communities exhibit similar patterns of phylogenetic structure within ***,we calculated NRI for local communities relative to the regional species pool and tested for an association with functional traits(plant height and seed mass)thought to vary along sea–inland *** Findings Regional species pools were phylogenetically clustered relative to the global pool,indicating regional *** showed stronger clustering than NRI pointing to the importance of especially recent diversifications within *** species pools grouped phylogenetically into two clusters on either side of the tropics suggesting greater dispersal rates within hemispheres than between *** NRI plot values confirmed that most communities were also phylogenetically clus

关键词： disturbance phylogenetic community structure plant functional traits plant height seed mass

The Expression of Fas/FasL in Peripheral Blood Lymphocytes and the Level of IL-2 in Serum of Patients with Condyloma Acuminata

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of huazhong University of Science and Technology(Medical Sciences) 2001年第2期21卷 171-173页

作者：刘厚君涂亚庭林能兴李家文黄长征刘志香 Department of Dermatology Xiehe Hospital Tongji Medical College Huazhong University of Science one Technology Wuhan

In order to investigate the role of the expression of the Fas/FasL in peripheral blood lymphocytes and the level of IL 2 in serum of patients with condyloma acuminata in the immune pathogenesis of CA, flow cytometry, indirect immunofluorescence labeling and ELISA were performed to detect the expression of the apoptotic regulatory proteins Fas/FasL in PBLC and the level of IL 2 in serum of 60 patients with different course of CA. The results showed that the expression of Fas/FasL in PBLC of the group of short course in CA was significantly higher than that of the normal controls ; the expression of Fas, FasL in PBLC of the group of long course CA was significantly higher than that of the group of short course and the normal controls ( P he level of IL 2 in serum of the group of short and long course CA was significantly lower than that of the group of normal controls ; the negative relation was revealed between the expression of Fas/FasL in PBLC and the level of IL 2 in serum of patients with CA . It was suggested that the abnormal apoptosis in PBLC and decreased level of IL 2 in serum of CA might play an important role in the course of CA.

关键词： Condyloma acuminata lymphocyte Fas/FasL IL 2