检索结果-南通市图书馆

Natural history and outcomes of patients with liver cirrhosis complicated by hepatic hydrothorax

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2022年第35期28卷 5175-5187页

作者： Sarah Romero andy kh lim Gurpreet Singh Chamani Kodikara Rachel Shingaki-Wells Lynna Chen Samuel Hui Marcus Robertson Department of Gastroenterology Monash HealthClayton 3168VictoriaAustralia Department of General Medicine School of Clinical SciencesMonash UniversityClayton 3168VictoriaAustralia Gastroenterology and Liver Transplant Unit Austin HealthHeidelberg 3084VictoriaAustralia

BACKGROUNDHepatic hydrothorax (HH) is an uncommon and difficult-to-manage complicationof cirrhosis with limited treatment *** define the clinical outcomes of patients presenting with HH managed withcurrent standards-of-care and to identify factors associated with *** patients with HH presenting to 3 tertiary centres from 2010 to 2018 wereretrospectively identified. HH was defined as pleural effusion in the absence ofcardiopulmonary disease. The primary outcomes were overall and transplant-freesurvival at 12-mo after the index admission. Cox proportional hazards analysiswas used to determine factors associated with the primary ***, 84 patients were included (mean age, 58 years) with a mean model forend-stage liver disease score of 29. Management with diuretics alone achievedlong-term resolution of HH in only 12% patients. At least one thoracocentesis wasperformed in 73.8% patients, transjugular intrahepatic portosystemic shuntinsertion in 11.9% patients and 33% patients received liver transplantation within12-mo of index admission. Overall patient survival and transplant-free survival at12 mo were 68% and 41% respectively. At multivariable analysis, current smoking [hazard ratio (HR) = 8.65, 95% confidence interval (CI): 3.43-21.9, P < 0.001) and acute kidneyinjury (AKI) (HR = 2.91, 95%CI: 1.21-6.97, P = 0.017) were associated with a significantly increasedrisk of *** patients with HH are a challenging population with a poor 12-mo survival despitecurrent treatments. Current smoking and episodes of AKI are potential modifiable factors affectingsurvival. HH is often refractory of diuretic therapy and transplant assessment should beconsidered in all cases.

关键词： Cirrhosis Portal hypertension Hepatic hydrothorax Ascites Liver transplantation

Rotator cuff repair with an interposition polypropylene mesh:A biomechanical ovine study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2023年第5期14卷 319-327页

作者： Winston Shang Rong lim andy khye Soon Yew Hannah Lie Siaw Meng Chou Denny Tijauw Tjoen Lie Department of Orthopaedic Surgery Singapore General HospitalSingapore 169856Singapore College of Engineering Nanyang Technical UniversitySingapore 797101Singapore

BACKGROUND Chronic large to massive rotator cuff tears are difficult to treat and re-tears are common even after surgical *** propose using a synthetic polypropylene mesh to increase the tensile strength of rotator cuff *** hypothesize that using a polypropylene mesh to bridge the repair of large rotator cuff tears will increase the ultimate failure load of the *** To investigate the mechanical properties of rotator cuff tears repaired with a polypropylene interposition graft in an ovine ex-vivo *** A 20 mm length of infraspinatus tendon was resected from fifteen fresh sheep shoulders to simulate a large *** used a polypropylene mesh as an interposition graft between the ends of the tendon for *** seven specimens,the mesh was secured to remnant tendon by continuous stitching while mattress stitches were used for eight *** specimens with an intact tendon were *** specimens underwent cyclic loading to determine the ultimate failure load and gap *** The mean gap formation after 3000 cycles was 1.67 mm in the continuous group,and 4.16 mm in the mattress group(P=0.001).The mean ultimate failure load was significantly higher at 549.2 N in the continuous group,426.4 N in the mattress group and 370 N in the intact group(P=0.003).CONCLUSION The use of a polypropylene mesh is biomechanically suitable as an interposition graft for large irreparable rotator cuff tears.

关键词： Rotator cuff repair Massive tear Interposition graft Biomechanics Polypropylene mesh

Mechano-responsive hydrogel for direct stem cell manufacturing to therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2023年第6期24卷 387-400页

作者： Yufeng Shou Ling Liu Qimin Liu Zhicheng Le khang Leng Lee Hua Li Xianlei Li Dion Zhanyun Koh Yuwen Wang Tong Ming Liu Zheng Yang Chwee Teck lim Christine Cheung andy Tay Department of Biomedical Engineering National University of Singapore117583Singapore Institute for Health Innovation&Technology National University of Singapore117599Singapore School of Civil Engineering and Architecture Wuhan University of Technology430070WuhanChina NUS Tissue Engineering Program National University of Singapore117510Singapore Lee Kong Chian School of Medicine Nanyang Technological University636921Singapore School of Mechanical and Aerospace Engineering Nanyang Technological University639798Singapore Institute of Molecular and Cell Biology Agency for ScienceTechnology and Research(A*STAR)138648Singapore Department of Orthopaedic Surgery Yong Loo Lin School of MedicineNational University of Singapore119288Singapore Mechanobiology Institute National University of Singapore117411Singapore

Bone marrow-derived mesenchymal stem cell(MSC)is one of the most actively studied cell types due to its regenerative potential and immunomodulatory *** cell expansion methods using 2D tissue culture plates and 2.5D microcarriers in bioreactors can generate large cell numbers,but they compromise stem cell potency and lack mechanical preconditioning to prepare MSC for physiological loading expected in *** overcome these challenges,in this work,we describe a 3D dynamic hydrogel using magneto-stimulation for direct MSC manufacturing to *** our technology,we found that dynamic mechanical stimulation(DMS)enhanced matrix-integrinβ1 interactions which induced MSCs spreading and *** addition,DMS could modulate MSC biofunctions including directing MSC differentiation into specific lineages and boosting paracrine activities(e.g.,growth factor secretion)through YAP nuclear localization and FAK-ERK *** our magnetic hydrogel,complex procedures from MSC manufacturing to final clinical use,can be integrated into one single platform,and we believe this‘all-in-one’technology could offer a paradigm shift to existing standards in MSC therapy.

关键词： Mesenchymal stem cell Dynamic mechanical stimulation Magnetic hydrogel Stem cell manufacturing Cell therapy

Dual ultra-wideband(UWB)radar-based sleep posture recognition system:Towards ubiquitous sleep monitoring

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

再生工程(英文) 2023年第1期4卷 36-43页

作者： Derek Ka-Hei Lai Li-Wen Zha Tommy Yau-Nam Leung andy Yiu-Chau Tam Bryan Pak-Hei So Hyo-Jung lim Daphne Sze Ki Cheung Duo Wai-Chi Wong James Chung-Wai Cheung Department of Biomedical Engineering Faculty of EngineeringThe Hong Kong Polytechnic UniversityHong Kong 999077China Department of Bioengineering Imperial CollegeLondon SW72AZUnited Kingdom Research Institute of Smart Ageing The Hong Kong Polytechnic UniversityHong KongChina School of Nursing The Hong Kong Polytechnic UniversityHong KongChina

Sleep posture monitoring is an essential assessment for obstructive sleep apnea(OSA)*** objective of this study is to develop a machine learning-based sleep posture recognition system using a dual ultra-wideband radar *** collected radiofrequency data from two radars positioned over and at the side of the bed for 16 patients performing four sleep postures(supine,left and right lateral,and prone).We proposed and evaluated deep learning approaches that streamlined feature extraction and classification,and the traditional machine learning approaches that involved different combinations of feature extractors and *** results showed that the dual radar system performed better than either single *** statistical features with random forest classifier yielded the best accuracy(0.887),which could be further improved via an ablation study(0.938).Deep learning approach using transformer yielded accuracy of 0.713.

关键词： Obstructive sleep apnea Deep learning Sleep monitoring Feature extraction Ablation study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

系统级封装(SiP)组装技术与锡膏特性

电子工业专用设备 2021年第2期50卷 67-70页

作者： Sze Pei lim Kenneth Thum andy Mackie David Hu 铟泰公司美国纽约州克林顿13323 铟泰公司江苏苏州215126

由于物联网“智慧”设备的快速发展,业界对能够在更小的封装内实现更多功能的系统级封装(SiP)器件的需求高涨[1],这种需求将微型化趋势推向了更高的层次:使用更小的元件和更高的密度来进行组装。无源元件尺寸已从01005(0.4 mm×0.2 mm)... 详细信息

由于物联网“智慧”设备的快速发展,业界对能够在更小的封装内实现更多功能的系统级封装(SiP)器件的需求高涨[1],这种需求将微型化趋势推向了更高的层次:使用更小的元件和更高的密度来进行组装。无源元件尺寸已从01005(0.4 mm×0.2 mm)缩小到008004(0.25 mm×0.125 mm),细间距锡膏印刷对SiP的组装来说变得越来越有挑战性。对使用不同助焊剂和不同颗粒尺寸锡粉的3种锡膏样本进行了研究;同时通过比较使用平台和真空的板支撑系统,试验了是否可以单独使用平台支撑来获得一致性较好的印刷工艺;并比较了激光切割和电铸钢网在不同开孔尺寸下的印刷结果。

关键词：系统级封装(SiP) 锡膏锡粉微型化

系统级封装(SiP)组装技术与锡膏特性(续)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

电子工业专用设备 2021年第3期50卷 65-69页

作者： Sze Pei lim Kenneth Thum andy Mackie David Hu 铟泰公司美国纽约州克林顿13323 铟泰公司江苏苏州215126

4结果和讨论4.1焊盘间的桥接结果比较表明,使用不同的治具配置有明显的区别。使用平台治具作为板支撑的激光切割钢网在80μm间隙的情况下未发现桥接。使用真空支撑时,激光切割钢网在50μm间隙的情况下也未发现桥接。这说明使用真空支撑... 详细信息

4结果和讨论4.1焊盘间的桥接结果比较表明,使用不同的治具配置有明显的区别。使用平台治具作为板支撑的激光切割钢网在80μm间隙的情况下未发现桥接。使用真空支撑时,激光切割钢网在50μm间隙的情况下也未发现桥接。这说明使用真空支撑在印刷时的钢网和电路板间间隙更小,支撑性能更好。图5显示了其在125μm×150μm焊盘(1∶1)和50μm焊盘间隙条件下的印刷效果。

关键词：组装技术激光切割桥接印刷效果焊盘锡膏钢网治具

Production and structural studies of alternatively spliced proteins

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Production and structural studies of alternatively spliced p...

防腐蚀、防氧化、抗静电、防霉菌的完整解决方案拦截科技——腐蚀防护的“最新技术水平”

The 4th ISGO International Conference on Structural Genomics

作者： Osnat Herzberg Kinlin Chao Sadhana Pullalarevu Visctoria Doseeva Natalia Gorlatova Igor Pechick Kap lim andy Howard John Orban John Moult Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA Biological Chemical and Physical Sciences Illinois Institute of Technology Chicago IL USA Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA Center for Advanced Research in Biotechnology University of Maryland Biotechnology Institute 9600 Gudelsky Dr. Rockville MD 20850 USA

＜正＞In high eukaryotes, a single pre-mRNA can produce many different mRNAs by using different combinations of exons, resulting in different protein products. It is believed that such mRNAs and protein products are responsible for diversifying and fine tuning the functions of the biological system. We are studying the impact of alternative splicing on structure to gain insight about how function diversity emerges by this mechanism. Most of the selected proteins are from human, and

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

防腐蚀、防氧化、抗静电、防霉菌的完整解决方案拦截科技——腐...

Corrigendum to‘Dual ultra-wideband(UWB)radar-based sleep posture recognition system:Towards ubiquitous sleep monitoring’[Engineered Regeneration 4(2023)36-43]

第二届全国重防腐蚀与高新涂料及涂装技术研讨会

作者：赖宝泉 andy lim W.K.Hum 科合亚洲有限公司 TEC-HUB ASIA LTD

日益精密的机械装备与高科技的电子设备都在面临着腐蚀/氧化/静电与霉菌这些难题的困扰。如何防护导致上述问题出现的存在于大气中的各种腐蚀性气体的侵略,工程师们用尽了各种方法,期待着一套完整的解决方案——Intercept technology(...

日益精密的机械装备与高科技的电子设备都在面临着腐蚀/氧化/静电与霉菌这些难题的困扰。如何防护导致上述问题出现的存在于大气中的各种腐蚀性气体的侵略,工程师们用尽了各种方法,期待着一套完整的解决方案——Intercept technology(腐蚀拦截科技)终于于1992年在美国朗讯贝尔试验室成功研发。经过不断的测试与改良,今天的Intercept包装材料,已经被尖端的高科技世界级企业所确认为保护各种精密电子产品与机械零件设备,防止腐蚀、氧化。污染与静电的灾害的国际“最新技术水平”

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

再生工程(英文) 2023年第2期4卷 223-223页

作者： Derek Ka-Hei Lai Li-Wen Zha Tommy Yau-Nam Leung andy Yiu-Chau Tam Bryan Pak-Hei So Hyo Jung lim Daphne Sze Ki Cheung Duo Wai-Chi Wong James Chung-Wai Cheung Department of Biomedical Engineering Faculty of EngineeringThe Hong Kong Polytechnic UniversityHong Kong 999077China Department of Bioengineering Imperial CollegeLondon SW72AZUnited Kingdom Research Institute of Smart Ageing The Hong Kong Polytechnic UniversityHong KongChina School of Nursing The Hong Kong Polytechnic UniversityHong KongChina

The authors regret that the name of the ethic committee that approved the study and the reference number was omitted from the published *** this research,all participants signed an informed consent after receiving an oral and written description of the experiment before the start of the *** study was approved by the Human Subjects Ethics HSEARS20210127007.

关键词： Engine wideband UWB