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Neural Regeneration Research 2023年第1期18卷 113-114页

作者： Norah A.Althobaiti Farid Menaa johnathan j.Dalzell Brian D.green Biology Department College of Science and Humanities-Al QuwaiiyahShaqra UniversityAl QuwaiiyahSaudi Arabia Departments of Internal Medicine and Nanomedicine Fluorotronics-California Innovations CorporationSan DiegoCAUSA Department of grassland and Plant Science AgriFood and Biosciences InstituteNorthern IrelandUK Institute for Global Food Security School of Biological SciencesQueen’s University BelfastBelfastUK

Biological models of Alzheimer’s disease(AD):Non-human models have contributed tremendously to the understanding of AD and its underlying pathological *** models have aided the investigation of the genetic and environmental risk *** also have enabled the progression of candidate therapies into human clinical *** of similarities with human brain anatomy and genetics,rodent models have been used extensively to recapitulate some aspects of AD pathology,measure AD-associated behavioral parameters and related nervous system dysfunctions(Eriksen and janus,2007).For instance,transgenic mice overexpressing human amyloid precursor protein have furthered the development of the amyloid cascade hypothesis as a central pillar of familial AD.

关键词： anatomy Alzheimer amyloid

Structure and sequence analysis of influenza A virus nucleoprotein

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Science China(Life Sciences) 2009年第5期52卷 439-449页

作者： NG andy Ka-Leung SHAW Pang-Chui Molecular Biotechnology Programme Department of Biochemistry and Centre for Protein Science and Crystallography The Chi-nese University of Hong Kong

Influenza A virus nucleoprotein (NP) forms homo-oligomers and multiple copies of NP wrap around genomic RNA, along with a trimeric polymerase making up ribonucleoprotein (RNP) complex. Sequence comparison of more than 2500 influenza A NP showed that this protein contains 30.1 % of polymorphic residues. NP is composed of a head and a body domain and a tail loop/ linker region. The head domain is more conserved than the body domain, as revealed from the structure-based sequence alignment. NP oligomerization is mediated by the insertion of the non-polymorphic and structurally conserved tail loop of one NP molecule to a groove of another NP. The different form of NP oligomers is due to the flexibility of the polymorphic linkers that join the tail loop to the rest of the protein. The RNA binding property of NP is known to involve the protruding element and the flexible basic loop between the head and body domains, both having high degree of primary sequence conservation. To bind RNA, NP may first capture the RNA by the flexible basic loop and then the RNA is clamped by the protruding element.

关键词： Influenza H5N1 nucleoprotein oligomerization RNA binding

Mass-Based Environmental Factor and Energy Assessment of Microwave-Assisted Synthesized Transition Metal Nanostructures

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American journal of Analytical Chemistry 2024年第6期15卷 201-218页

作者： Victor j. Law School of Mechanical and Materials Engineering University College Dublin Dublin Ireland

This paper describes mass-based energy phase-space projection of microwave-assisted synthesis of transition metals (zinc oxide, palladium, silver, platinum, and gold) nanostructures. The projection uses process energy budget (measured in kj) on the horizontal axes and process density (measured in kjg−1) on the vertical axes. These two axes allow both mass usage efficiency (Environmental-Factor) and energy efficiency to be evaluated for a range of microwave applicator and metal synthesis. The metrics are allied to the: second, sixth and eleventh principle of the twelve principle of green Chemistry. This analytical approach to microwave synthesis (widely considered as a useful green Chemistry energy source) allows a quantified dynamic environmental quotient to be given to renewable plant-based biomass associated with the reduction of the metal precursors. Thus allowing a degree of quantification of claimed “eco-friendly” and “sustainable” synthesis with regard to waste production and energy usage.

关键词： Microwave-Assisted Synthesis Transition Metals Nanostructures Allometry Scaling Power-Law Signature green Chemistry

Comparative studies on storage cells in tardigrades during starvation and anhydrobiosis

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Current Zoology 2010年第2期56卷 259-263页

作者： andy REUNER Steffen HENGHERR Franz Brümmer Ralph O.SCHILL Universitt Stuttgart Biological Institute Zoology UniversittStuttgart Biological Institute Zoology

The impact of starvation and anhydrobiosis on the number and size of the storage cells in the tardigrade species Milnesium tardigradum, Paramacrobiotus tonollii and Macrobiotus sapiens was investigated to gain more insight on the energetic side of anhydrobiosis. Storage cells are free floating cells within the body cavity of tardigrades and are presumed to store and release energy in form of glycogen, protein and fat to maintain a constant nutrient regime for the other tissues. The body size of the animals was not correlated with the size of the storage cells, however, M. tardigradum the largest species analysed also had the largest storage cells. A reduction in the size of the storage cells is apparent in all three species after seven days of starvation. A seven-day period of anhydrobiosis leads to a decrease in cell size in M. tardigradum but not in P. tonollii and M. sapiens. Although M. sapiens was raised on green algae, and M. tardigradum and P. tonollii were fed with rotifers and nematodes this difference in nourishment was not reflected in the response of the storage cells to anhydrobiosis

关键词： Tardigrada cryptobiosis Milnesium tardigradum Paramacrobiotus tonollii Macrobiotus sapiens

CHECKING CONSISTENCY IN INFORMATION MODELS BY USING CONSTRAINT PROGRAMMING

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Transactions of Nanjing University of Aeronautics and Astronautics 2005年第1期22卷 30-37页

作者：方捷 KAHN Hilary j CARPENTER andy 曼彻斯特大学计算机学院曼彻斯特M139PL英国

This paper addresses the issue of checking consistency in information models. A method based on constraint programming is proposed for identifying inconsistency or proving consistency in information models. The system described here checks information models written in the ISO standard information modelling language EXPRESS. EXPRESS is part of the ISO STEP standard used in the manufacturing and process industries. This paper describes the checking procedure, including EXPRESS model formalization, constraint satisfaction problem (CSP) derivation from the formalized model and satisfaction checking of the derived CSPs. This paper shows a new domain in which constraint programming can be exploited as model verification and validation.

关键词： EXPRESS model constraint programming model verification

Thermochemical co-conversion of biomass-plastic waste to biochar:a review

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green Chemical Engineering 2024年第1期5卷 31-49页

作者： Adewale George Adeniyi Kingsley O.Iwuozor Ebuka Chizitere Emenike Oluwaseun j.Ajala Samuel Ogunniyi Kabir B.Muritala Department of Chemical Engineering Faculty of Engineering and TechnologyUniversity of IlorinIlorinP.M.B.1515Nigeria Department of Chemical Engineering Landmark UniversityOmu-AranKwara StateP.M.B.1001Nigeria Department of Pure and Industrial Chemistry Nnamdi Azikiwe UniversityAwkaP.M.B.5025Nigeria Department of Chemistry Federal University of TechnologyBosso CampusMinnaNiger StateP.M.B.65Nigeria

Biomass and plastics are two of the most common municipal solid wastes globally that have continuously placed a burden on the *** is therefore important that they are properly *** coconversion offers a valuable opportunity to recycle biomass and plastics simultaneously into biochar,which reduces the time and cost of recycling them individually while producing a material with a wide range of *** study is a review of published literature that discusses the thermochemical co-processing of biomass and plastic wastes into *** was observed that co-pyrolysis and co-hydrothermal carbonization are the most commonly utilized technologies for this *** characteristics of different biomass and plastics that have been thermochemically converted into biochar were *** properties of the resulting biochar are affected by the feedstock composition,pre-treatment and blending ratio,the reactor’s configuration,reaction temperature,and the presence of a *** studies found that treating the feedstocks separately resulted in a lower yield of biochar than processing them *** biochar created by this procedure has been used as a soil additive and as an adsorbent for water *** perspectives and suggestions,such as the necessity for some technical advancement,biochar’s economic benefits,improved government participation,and raised social awareness,were also *** factors have the potential to propel this field of study to great horizons.

关键词： Biomass Co-pyrolysis Plastic Thermochemical process Valorization

Author Correction:Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1

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Cellular & Molecular Immunology 2023年第3期20卷 310-310页

作者： jan Novak Matthew B.Renfrow R.Glenn King Colin Reily Todd j.green Department of Microbiology University of Alabama at Birmingham Birmingham AL USA Department of Medicine University of Alabama at Birmingham Birmingham AL USA Department of Biochemistry and Molecular Genetics University of Alabama at Birmingham Birmingham AL USA

In the sentence beginning"H chain genes are assembled from one functional variable(B),one diversity(D),and.."in this article,the text should have read"H chain genes are assembled from one functional variable(M),one di... 详细信息

关键词： IgA1 secretory serum

Laboratory evaluation of toxicity of selected insecticides against egg and larval stages of cotton pink bollworm, Pectinophora gossypiella (Saunders) (Lepidoptera: Gelechiidae)

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journal of Cotton Research 2024年第1期7卷 15-28页

作者： BUSNOOR Abhishek V. WADASKAR R.M. FAND Babasaheb B. TAMBE V.j. PILLAI T. MAHULE D.j. NAGRARE V.S. PRASAD Y.G. Entomology Section College of Agriculture(Dr.Panjabrao Deshmukh Krishi Vidyapeeth)Nagpur 440001MaharashtraIndia Indian Council of Agricultural Research-Central Institute for Cotton Research Nagpur 441108MaharashtraIndia

Background The cryptic nature of pink bollworm Pectinophora gossypiella(Saunders)larvae enables its reduced vul-nerability to insecticidal ***,the development of resistance against Bacillus thuringiensis(Bt)toxins posed a serious threat to transgenic cotton *** necessitated determining the critical timing of spray applications on the control *** study assessed the influence of egg age(freshly laid ***-day-old)and the loca-tion of larvae(directly exposed to the insecticide residues on the boll rind *** inside the bolls)on insecticide control *** The results revealed a significant decrease in the ovicidal activity of tested insecticides with an increase in the age of eggs from one day old to three days old(paired t-test,P80%mortality)than the larvae exposed after they had bur-rowed inside the bolls(green bolls of cotton were relatively less susceptible to the insecticide *** toxic effects of insecticides on egg and larval stages were primar-ily *** findings are significant for devising a comprehensive strategy for pink bollworm management on a sustainable basis.

关键词： Bioefficacy Cotton Insecticides Pink bollworm Pectinophora gossypiella Timings of spray

Antiplatelet aggregation activity of some ferrocenylphenylimine compounds

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journal of Chinese Pharmaceutical Sciences 2017年第6期26卷 460-464页

作者： Monisola I.Ikhile Foluso O.Osunsanmi andy R.Opoku j.Catherine Ngila Department of Applied Chemistry University of JohannesburgDoornfontein Campus Department of Biochemistry and Microbiology University of Zululandprivate Bag X1001

Platelet hyper-aggregability triggered death and disability due to cardiovascular diseases is increasing worldwide and becoming a global concern. Therefore, it is necessary to synthesize newer drugs for the management of platelet aggregation. In this study, we investigated the antiplatelet aggregation activity of a novel series of ferrocenylimine compounds(3–10), N-(3-nitro-2-hydroxylbenzylidene)-3-ferrocenylimine(3), N-(3-bromo-2-hydroxylbenzylidene)-3-ferrocenylimine(4), N-(3-bromo-5-chlorosalicylidene)-3-ferrocenylimine(5), N-(ferrocenylformidene)-3-ferrocenylimine(6), N-(3-nitro-2-hydroxylbenzylidene)-4-ferrocenylimine(7), N-(3-bromo-2-hydroxylbenzylidene)-4-ferrocenylimine(8), N-(3-bromo-5-chlorosalicyl)-4-ferrocenylimine(9), N-(ferrocenylformidene)-4-ferrocenylimine(10) on thrombin-and ADP-induced platelet aggregation. The synthesized ferrocenylimine compounds(3–10) were found to exhibit higher antiplatelet aggregation activity than their precursors, which are 3-ferrocenylaniline(compound 1) and 4-ferrocenylaniline(compound 2). Among the derivatives, compounds 5, 6 and 10 possessed excellent platelet aggregation inhibition against the agonists.

关键词： Ferrocene Imine Antiplatelet aggregation Thrombin Platelet