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NH_(3)laser THz emission under optical pumping by“long”(~100μs)CO_(2)laser pulses

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Chinese Optics Letters 2023年第2期21卷 133-137页

作者： andrey Alekseevich Ionin Igor Olegovich Kinyaevskiy Yuri Mikhailovich Klimachev andrey Yurievich Kozlov Darya Ivanovna Kormashova andrey Alexandrovich Kotkov Yury Alekseevich Mityagin Sergey Alexandrovich Savinov Adilya Maratovna Sagitova Dmitry Vasilievich Sinitsyn Maxim vladimirovich Ionin P.N.Lebedev Physical Institute of the Russian Academy of Sciences Moscow 119991Russia

Terahertz(THz)NH_(3) lasing with optical pumping by electron-beam-sustained discharge“long”(~100μs)CO_(2) laser pulses was *** NH3laser emission pulses and the“long”pulses of the CO_(2) pump laser were simultaneously measured with nanosecond response *** NH3 lasing duration and its delay with respect to the pump pulse were measured for various CO_(2) laser pulse *** the CO_(2) laser pump line 9R(30),three wavelengths of 67.2,83.8,and 88.9μm were *** the CO_(2) laser pump line 9R(16),only a single NH3 laser line with a wavelength of 90.4μm was detected.

关键词： NH3 laser CO_(2)laser terahertz emission nanosecond response time

Process-Functional Model of Transportation Mix Concrete

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Journal of Transportation Technologies 2014年第2期4卷 157-163页

作者： andrey vladimirovich Ostroukh Bashmakov Igor Aleksandrovich Polgun Mikhail Borisovich Department of Automated Control Systems Moscow Automobile & Road Construction State Technical University Moscow Russia Department of Management Moscow Automobile & Road Construction State Technical University Moscow Russia

The paper proposes a process-functional model of transportation mix concrete, which is a structured description of a means of transportation technology mix concrete road at the level of the production process. Range of activities related to the transportation of concrete mixtures is presented in the form of hierarchically nested processes that are coordinated on the basis of general systems theory. The model is described in a strict sequence: process chain→process step→process link, and all built technological chains consist of indivisible units.

关键词： Road Transport Process Chain The Transport Process Transportation of Concrete Mixes

Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries

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World Journal of Clinical Cases 2023年第2期11卷 322-331页

作者： Olga Vladislavovna Stepanova Grigorii Andreevich Fursa Svetlana Sergeevna Andretsova Valentina Sergeevna Shishkina Anastasia Denisovna Voronova andrey Viktorovich Chadin Ekaterina Konstantinovna Karsuntseva Igor vladimirovich Reshetov Vladimir Pavlovich Chekhonin Department of Basic and Applied Neurobiology V.P.Serbsky National Medical Research Center for Psychiatry and NarcologyMoscow 119034Russia Department of Neurohumoral and Immunological Research National Medical Research Center of CardiologyMoscow 121552Russia Department of Biology Moscow State UniversityMoscow 119991Russia Department of Plastic Surgery I.M.Sechenov First Moscow State Medical UniversityMoscow 119435Russia Department of Medical Nanobiotechnologу N.I.Pirogov Russian National Research Medical UniversityMoscow 117997Russia

The review focuses on the most important areas of cell therapy for spinal cord *** mucosa cells are promising for *** these cells is safe for *** use of olfactory mucosa cells is effective in restoring motor function due to the remyelination and regeneration of axons after spinal cord *** cells express neurotrophic factors that play an important role in the functional recovery of nerve tissue after spinal cord *** addition,it is possible to increase the content of neurotrophic factors,at the site of injury,exogenously by the direct injection of neurotrophic factors or their delivery using gene *** advantages of olfactory mucosa cells,in combination with neurotrophic factors,open up wide possibilities for their application in threedimensional and four-dimensional bioprinting technology treating spinal cord injuries.

关键词： Olfactory mucosa cells Neurotrophic factors Cell therapy Injury of spinal cord Three-dimensional bioprinting Four-dimensional bioprinting

X-Ray and VUV Spectra from the Laser Plasma Produced with “Kanal-2” Facility

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Journal of Modern Physics 2014年第2期5卷 92-97页

作者： andrey Aleksandrovich Kologrivov Mikhail vladimirovich Osipov Victor Nikolaevich Puzyrev Alexandr Nikolaevich Starodub Oleg Feliksovich Yakushev P. N. Lebedev Physical Institute of RAS Moscow Russia

The paper presents experimental results obtained on “Kanal-2” facility. Laser radiation focusing on the surface of plane magnesium targets created the high temperature plasma, which emitted X-ray and vacuum ultraviolet (VUV) radiation. This radiation spectrum was investigated with two spectrographs: the mica crystal spectrograph (working range 8.2 ? - 9.6 ?) and the grazing incidence VUV spectrograph (working rage 30 ? - 130 ?). A set of beryllium stepwise attenuators appended the diagnostic complex and allowed us to get an approximated picture of a continuous spectrum within the range of 2.2 ? - 6.2 ?. The estimation of the plasma electron temperature Te from the ratio between the intensity of the dielectronic satellites and the resonance line gives Te ~ 180 eV. The ratio between the intensity of the resonance and intercombination lines gives the electron density of the emitting zone ne ~ 2 × 1019 cm-3. Some lines observed within the spectral range of 8.5 ? - 9.1 ? belong to none of the transitions of Mg ions. Perhaps the observed spectrum is determined by the transitions in so-called hollow ions of Mg, i.e. in the ions with unfilled inner shells. The spectra obtained with the grazing incidence spectrograph and with the minimum-directioned discrepancy iteration method of spectrum reconstruction from the attenuation curve in the beryllium stepwise attenuators are also presented.

关键词： Laser Plasma X-Ray Spectra VUV Spectra Plasma Diagnostics

CYP2C19＊2, CYP2C19＊3, CYP2C19＊17 Allele and Genotype Frequencies in Clopidogrel-Treated Patients with Coronary Heart Disease in Russian

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Journal of Pharmacy and Pharmacology 2014年第5期2卷 322-326页

作者： Karin Badavievich Mirzaev Dmitriy Alekseyevich Sychev Alia Sergeyevna Yugay andrey vladimirovich Grachev Ruslan Yevgenyevich Kazakov Department of Clinical Pharmacology 1.M. Sechenov First Moscow State Medical University Moscow 119991 Russian Federation Department of Therapeutics and Clinical Pharmacology Russian Medical Academy of Postgraduate Education Moscow 123995Russian Federation Department of Cardiology "SM-clinic" Medical Center Moscow 134544 Russian Federation Center for Clinical Pharmacology Scientific Center on Expertise of Medical Application Products Moscow 109240 Russian Federation

Individual variation in the response to drug therapy has been mainly attributed to the genetic polymorphism of cytochrome P 450 isoenzymes. Mutation in the gene CYP2C19 （cytochrome P450 2C19） has been shown to influence the clinical efficiency of clopidogrel. The aim is to investigate the frequencies of CYP2C19＊2 （c.G681A; rs4244285）, CYP2C19＊3 （c.G636A; rs4986893）, CYP2C19＊17 （c.C806T; rs12248560） and to compare the allele and genotype frequencies of CYP2C19＊2 in patients with CHD （coronary heart disease） to healthy volunteers. We examined 53 patients with CHD received clopidogrel and 146 healthy volunteers. CYP2C19＊2, CYP2C19＊3, CYP2C19＊17 carriages were determined by a polymerase-chain reaction. The observed genotype distribution did not deviate from Hardy-Weinberg equilibrium, it was determined by a Chi-square test with Yates correction. The frequency of CYP2C19＂2 allele reported in patients with CHD and in the healthy volunteers was 16.6% and 13.3%, respectively （P = 0.584）. The results of the present study may be helpful in developing current and future directions for its management.

关键词： CYP2C19*2 CYP2C19*17 CYP2C19 polymorphism pharmacogenetics clopidogrel resistance Russian population.