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Open Journal of Orthopedics 2014年第9期4卷 249-256页

作者： Bassel El-Osta Ali Ghoz Alice Dawson mark andrews St. George’s Hospital London UK Scarborough General Hospital Scarborough UK

There are several prosthetic knee designs currently in use. There are however very few studies comparing long-term functional outcomes between patients using different models of knee pros-thesis in elective knee replacement. In this study, we used the validated Oxford Knee Score (OKS) to retrospectively compare the outcomes of a total of 1635 patients who had an elective total knee replacement in a large District General Hospital, using fifteen different models of knee prosthesis, over a ten-year period. The average scores reported by all patient groups showed significant improvement by three months post-operatively (pre-operative mean score 15.8, post-operative mean score 39.4, p < 0.05), and remained similar for all models of prosthesis used over the total ten-year period. Based on the OKS as an assessment tool, we report no significant difference in long-term functional outcomes for this group of patients following an elective knee replacement, regardless of the type of prosthesis used.

关键词： Patients Outcome Knee Prosthesis Total Knee Replacement Variable Knee Prosthesis OKS on Prosthesis

18GHz移动通讯回程应用需要高效1W GaAs MMIC放大器

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电子设计技术 EDN CHINA 2010年第10期17卷 63-63,66页

作者： James Nelson mark andrews TriQuint半导体

为满足第四代数据传输服务的需要,无线通讯业已向LTE（长期演进）迅猛发展。虽然某些地区的不同标准将仍继续存在,世界上绝大部分的无线系统运营商会将依赖LTE作为他们4G平台的所有或相当大的组成部分。LTE能实现高质量视频流传输和文... 详细信息

为满足第四代数据传输服务的需要,无线通讯业已向LTE（长期演进）迅猛发展。虽然某些地区的不同标准将仍继续存在,世界上绝大部分的无线系统运营商会将依赖LTE作为他们4G平台的所有或相当大的组成部分。LTE能实现高质量视频流传输和文件速传等数据密集应用。

关键词： 4G平台LTE 移动通讯回程 1-WGaAs功率放大器 TGA4532-SM TriQuint

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制动助力器在挖掘装载机上的应用

工程机械与维修 2013年第1期 179-179页

作者： Chad Oney mark andrews 沈雁冰

挖掘装载机机动灵活,广泛用于道路建设、电缆铺设以及自来水、污水、热力管网建设和维修。制动助力器作为挖掘装载机制动系统的核心零部件,关系到其行驶的安全性和可靠性。本文以美国卡莱制动与摩擦材料公司（CBF）Booster系列制动助力... 详细信息

挖掘装载机机动灵活,广泛用于道路建设、电缆铺设以及自来水、污水、热力管网建设和维修。制动助力器作为挖掘装载机制动系统的核心零部件,关系到其行驶的安全性和可靠性。本文以美国卡莱制动与摩擦材料公司（CBF）Booster系列制动助力器为例,介绍挖掘装载机制动助力器的安装及应用技术。

关键词：制动助力器挖掘装载机应用道路建设电缆铺设管网建设制动系统摩擦材料

Underground mine stream crossing assessment:A multi-disciplinary approach

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International Journal of Mining Science and Technology 2021年第1期31卷 59-65页

作者： Kevin andrews Steve Keim Marshall Miller&Associates BluefieldVA 24605USA

Underground mine designs typically try to avoid extraction beneath streams and rivers of any significant size,especially when the overburden rock thickness between the stream bed and the mine is *** issues with mining beneath streams include excessive groundwater inflow to the mine,weak ground(roof,floor,and pillar)conditions,horizontal stress effects,as well as stream loss and other potential adverse environmental ***,there are times when crossing beneath a stream or river is necessary to move into a new area of mineral reserve without creating additional mine access points from the ground ***,stream crossings are completed without thorough assessment,potentially resulting in increased costs,decreased safety,and,in some cases,failure to advance the *** of the most favorable location(s)to cross the stream must account for numerous factors and the associated assessment often requires a multi-disciplinary *** crossing investigations often require geological,hydrogeological,geotechnical,and geophysical *** of stream crossing investigations include desktop evaluation of maps and aerial photography,stream bed observations,drilling,detailed rock core logging,downhole geophysical surveying,hydraulic conductivity testing(packer testing),geotechnical laboratory testing,assessment,and *** deliverables from a stream crossing assessment typically include geological,geotechnical,and hydrogeological characterization of potential stream crossing locations,classification of favorable and unfavorable crossing locations,recommendations for entry design and pillar sizing,and recommendations for if,and how,to conduct pre-grouting *** of technical aspects of data collection and assessment are provided based on decades of industry experience conducting stream crossing assessments in various underground mining scenarios.

关键词： Underground mining Geotechnical Stream-crossing Hydrogeology Characterization

Is cardiac resynchronisation therapy feasible, safe and beneficial in the very elderly？

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Journal of Geriatric Cardiology 2015年第5期12卷 497-501页

作者： Bartosz Olechowski Rebecca Sands Donah Zachariah Neil P andrews Richard Balasubramaniam mark Sopher John Paisey Paul R Kalra Royal Bournemouth Hospital NHS Foundation Trust Bournemouth UK Queen Alexandra Hospital Portsmouth Hospitals NHS Trust Portsmouth UK

Objective To evaluate whether cardiac resynchronisation therapy （CRT） implantation was feasible and safe in octogenarians and the asso- ciation with symptoms. Methods Consecutive patients undergoing CRT implantation were recruited from two UK centers. Patients grouped according to age：〈 80 ＆ ≥ 80 years. Baseline demographics, complications and outcomes were compared between those groups. Results A total of 439 patients were included in this study, of whom 26% were aged ≥ 80 years. Octogenarians more often received cardiac resynchronization therapy pacemaker in comparison to cardiac resynchronisation therapy-defibrillator. Upgrade from pacemaker was common in both groups （16% 〈 80 years vs. 22% ≥ 80 years, P = NS）. Co-morbidities were similarly common in both groups （overall diabetes： 25%, atrial fibrillation： 23%, hypertension： 45%）. More patient age ≥ 80 years had significant chronic kidney disease （CKD, estimated glomerular filtration rate 〈 45 mL/min per 1.73 m^2, 44% vs. 22%, P 〈 0.01 ）. Overall complication rates （any） were similar in both groups （16% vs. 17%, P = NS）. Both groups demonstrated symptomatic benefit. One-year mortality rates were almost four fold greater in octogenarians as compared with the younger cohort （13.9% vs. 3.7%, P 〈 0.01）. Conclusions CRT appears to be safe in the very elderly despite extensive co-morbidity, and in particular frequent severe CKD. Symptomatic improvement appears to be meaningful. Strategies to increase the appropriate identification of elderly patients with CHF who are potential candidates for CRT are required.

关键词： Cardiac resynchronisation therapy Heart failure Left ventricular dysfunction Safety The elderly

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Non-physician endoscopists: A systematic review

1000年

作者： by mark Galer and Philip andrews.

来源：畅想之星图书光盘版（南... 评论

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World Journal of Gastroenterology 2015年第16期21卷 5056-5071页

作者： Maximilian Stephens Luke F Hourigan mark Appleyard George Ostapowicz mark Schoeman Paul V Desmond Jane M andrews Michael Bourke David Hewitt David A Margolin Gerald J Holtmann Department of Gastroenterology and Hepatology Princess Alexandra Hospital Faculty of Medicine and Biomedical Sciences University of Queensland Department of Gastroenterology and Hepatology RBWH Department of Gastroenterology and Hepatology Gold Coast Hospital QLD 4215 Department of Gastro-enterology and Hepatology Royal Adelaide Hospital and University of Adelaide St Vincent’s Hospital University of MelbourneMelbourne VIC 3010Australia Department of Gastroenterology and Hepatology Westmead HospitalUniversity of Sydney School of Medicine University of Queensland Department of Gastroenterology Queensland Elizabeth II Jubilee HospitalCoopers PlainsBrisbane QLD 4108Australia Department of Colon and Rectal Surgery Ochsner Clinic Foundation Ochsner Clinical SchoolUniversity of Queensland

AIM:To examine the available evidence on safety, competency and cost-effectiveness of nursing staff providing gastrointestinal(GI) endoscopy ***:The literature was searched for publications reporting nurse endoscopy using several databases and specific search *** were screened against eligibility criteria and for *** searches yielded 74 eligible and relevant articles; 26 of these studies were primary research articles using original datasets relating to the ability of nonphysician *** publications included a total of 28883 procedures performed by non-physician ***:The number of publications in the field of non-specialist gastrointestinal endoscopy reached a peak between 1999 and 2001 and has decreased thereafter.17/26 studies related to flexible sigmoidoscopies,5 to upper GI endoscopy and 6 to *** studies were from metropolitan centres with nurses working under strict supervision and guidance by specialist *** distribution of publications showed the majority of research was conducted in the United States(43%),the United Kingdom(39%)and the Netherlands(7%).Most studies conclude that after appropriate training nurseendoscopists safely perform ***,in relation to endoscopic competency,safety or patient satisfaction,all studies had major methodological *** were often not randomized(21/26studies)and not appropriately *** relation to cost-efficiency,nurse endoscopists were less costeffective per procedure at year 1 when compared to services provided by physicians,due largely to the increased need for subsequent endoscopies,specialist follow-up and primary care ***:Contrary to general beliefs,endoscopic services provided by nurse endoscopists are not more cost effective compared to standard service models and evidence suggests the *** significant shortcomings and biases limit the validity and

关键词： Nurse endoscopist Cost-benefit Servicemodel Patient satisfaction Outcome parameter

Gastroesophageal reflux disease after diagnostic endoscopy in the clinical setting

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World Journal of Gastroenterology 2013年第16期19卷 2514-2520页

作者： Nora B Zschau Jane M andrews Richard H Holloway mark N Schoeman Kylie Lange William CE Tam Gerald J Holtmann Department of Gastroenterology and Hepatology Royal Adelaide Hospital Faculty of Health Sciences University of AdelaideAdelaide Department of Gastroenterology and Hepatology Lyell McEwin Hospital Department of Gastroenterology and Hepatology University of Queensland School of Medicine Princess Alexandra Hospital

AIM: To investigate the outcome of patients with symptoms of gastroesophageal reflux disease (GERD) referred for endoscopy at 2 and 6 mo post endoscopy. METHODS: Consecutive patients referred for upper endoscopy for assessment of GERD symptoms at two large metropolitan hospitals were invited to participate in a 6-mo non-interventional (observational) *** two institutions are situated in geographically and socially disparate areas. Data collection was by selfcompletion of questionnaires including the patient assessment of upper gastrointestinal disorders symptoms severity and from hospital records. Endoscopic finding using the Los-Angeles classification, symptom severity and it's clinically relevant improvement as change of at least 25%, therapy and socio-demographic factors were assessed. RESULTS: Baseline data were available for 266 patients and 2-mo and 6-mo follow-up data for 128 and 108 patients respectively. At baseline, 128 patients had erosive and 138 non-erosive reflux disease. Allmost all patient had proton pump inhibitor (PPI) therapy in the past. Overall, patients with non-erosive GERD at the index endoscopy had significantly more severe symptoms as compared to patients with erosive or even complicated GERD while there was no difference with regard to medication. After 2 and 6 mo there was a small, but statistically significant improvement in symptom severity (7.02 ± 5.5 vs 5.9 ± 5.4 and 5.5 ± 5.4 respectively); however, the majority of patients continued to have symptoms (i.e. , after 6 mo 81% with GERD symptoms). Advantaged socioeconomic status as well as being unemployed was associated with greater improvement. CONCLUSION: The majority of GORD patients receive PPI therapy before being referred for endoscopy even though many have symptoms that do not sufficiently respond to PPI therapy.

关键词： Gastroesophageal reflux disease Epidemiology Proton pump inhibitor Acid suppressive therapy Endoscopy Barrett’s esophagus Functional gastrointestinal disorders

英国亨伯河口湾的营养物通量——过去、现在和未来

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AMBIO－人类环境杂志 2000年第3期29卷 130-135页

作者： Timothy Jickells Julian andrews Gregory Samways Richard Sanders Stephen Malcolm David Sivyer Ruth Parker David Nedwell mark Trimmer John Ridgway 雷利卿

本文描述了从3000年前的全新世到如今的英国亨伯河口湾的地貌状况。在这一时期,潮间带90%以上的面积和河口湾90%以上的沉积储存能力囚开垦而消失了。在许多其它已经都市化的河口湾地带也有类似情形。由于潮间带的消失,如今河口湾中沉淀... 详细信息

本文描述了从3000年前的全新世到如今的英国亨伯河口湾的地貌状况。在这一时期,潮间带90%以上的面积和河口湾90%以上的沉积储存能力囚开垦而消失了。在许多其它已经都市化的河口湾地带也有类似情形。由于潮间带的消失,如今河口湾中沉淀的养分收支量都表现为很少的养分储存能力。我们对全新世亨伯河口湾的营养物质建立了推测性质的收支计算,提出那时的河口湾能够有效地储集大量的氮和磷。本文还提出了一种收支算法,说明亨伯河口湾的营养物质以现代的营养成分负荷而在开发之前的地理环境之下是如何循环的。结果显示在这种状况下,从亨伯河口湾流向北海的养分流是明显减弱的。我们根据可预测的海平面上升程度而对河口湾进行重新调整的各种方案,对研究结果进行了讨论。

关键词：英国亨伯河湾营养物通量地貌变化