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Towards Physarum Robots: Computing and Manipulating on Water Surface

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Journal of Bionic Engineering 2008年第4期5卷 348-357页

作者： andrew adamatzky Jeff Jones Department of Computer Science University of the West of England

Plasmodium of Physarum polycephalum is an ideal biological substrate for implementing concurrent anu parauel computation, including combinatorial geometry and optimization on graphs. The scoping experiments on Physarum computing in conditions of minimal friction, on the water surface were performed. The laboratory and computer experimental results show that plasmodium of Physarum is capable of computing a basic spanning tree and manipulating of light-weight objects. We speculate that our results pave the pathways towards the design and implementation of amorphous biological robots.

关键词： biological computing amorphous robots unconventional computation amoeba

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Bio-Imitation of Mexican Migration Routes to the USA with Slime Mould on 3D Terrains

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Journal of Bionic Engineering 2013年第2期10卷 242-250页

作者： andrew adamatzky Genaro J Martinez Department of Computer Sciences University of the West of England Bristol BS16 1QY UK Escuela Superior de Computo Instituto Politecnico Nacional Mexico

Plasmodium ofPhysarum polycephalum （P. polycephalum） is a large single cell visible by an unaided eye. It shows sophisticated behavioural traits in foraging for nutrients and developing an optimal transport network of protoplasmic tubes spanning sources of nutrients. When placed in an environment with distributed sources of nutrients the cell computes＇ an optimal graph spanning the nutrients by growing a network of protoplasmic tubes. P. polycephalum imitates development ofman-made transport networks of a country when configuration of nutrients represents major urban areas, We employed this feature of the slime mould to imitate mexican migration to USA. The Mexican migration to USA is the World＇s larger migration system. We bio-physically imitated the migration using slime mould P. poIycephalum. In laboratory experiments with 3D Nylon terrains of USA we imitated development of migratory routes from Mexico-USA border to ten urban areas with high concentration of Mexican migrants. From results of laboratory experiments we extracted topologies of migratory routes, and highlighted a role of elevations in shaping the human movement networks.

关键词： biomimetics bio-inspired computing migration routes slime mould

Sounds Synthesis with Slime Mould of Physarum Polycephalum

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Journal of Bionic Engineering 2011年第2期8卷 107-113页

作者： Eduardo R. Miranda andrew adamatzky Jeff Jones Interdisciplinary Centre.for Computer Music Research (ICCMR) University of Plymouth Plymouth PL48AA UK Unconventional Computing Centre University of the West of England Bristol BSI 61QY UK

This paper introduces a novel application of bionic engineering： a bionic musical instrument using Physarum polycephalum. Physarum polycephalum is a huge single cell with thousands of nuclei, which behaves like a giant amoeba. During its foraging behavior this plasmodium produces electrical activity corresponding to different physiological states. We developed a method to render sounds from such electrical activity and thus represent spatio-temporal behavior of slime mould in a form apprehended auditorily. The electrical activity is captured by various electrodes placed on a Petri dish containing the cultured slime mold. Sounds are synthesized by a bank of parallel sinusoidal oscillators connected to the electrodes. Each electrode is responsible for one partial of the spectrum of the resulting sound. The behavior of the slime mould can be controlled to produce different timbres.

关键词： Physarum polycephalum bionic musical instrument unconventional computing sound synthesis sonification

Slime mould imitates transport networks in China

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International Journal of Intelligent Computing and Cybernetics 2013年第3期6卷 232-251页

作者： andrew adamatzky Xin-She Yang Yu-Xin Zhao Unconventional Computing Centre University of the West of EnglandBristolUK Mathematics and Scientific Computing National Physical LaboratoryTeddingtonUK Middlesex University LondonUK School of Automation Harbin Engineering UniversityHarbinChina

Purpose-The purpose of this paper is to study the slime mould Physarum polycephalum as an ideal biological substrate for transport *** presented with several sources of nutrients the slime mould propagates colonises the sources and spans them with a network of protoplasmic tubes allegedly optimised for transfer of nutrients and *** formation of slime mould’s protoplasmic network resembles development of man-made transport ***,it sounds reasonable to compare the protoplasmic network with an established network of vehicular transport links to uncover potential(dis-)similarities between slime mould grown and man-made networks and shed more light onto general principle guiding growing biological and socio-engineering ***/methodology/approach-The paper proceeds by representing major urban areas of China by oat flakes,inoculating the slime mould in Beijing,waiting till the slime mould colonises all urban areas,or colonises some and cease further propagation,and analysing the protoplasmic networks formed and comparing with man-made motorway network and planar proximity ***-Laboratory experiments found that *** provides a very good match for the Chinese motorway ***,both the Chinese motorway network and the slime mould protoplasmic networks have minimum spanning trees and other proximity graphs as their *** experiments also identified the urban areas unlikely to be spanned by the protoplasmic networks,which may reflect hot-spots in existing challenges of modernising the ***/value-The paper demonstrated the strong component of transport system built by slime mould of *** on major urban areas of China consisting of one chain of four nodes and one planar graph with three leaves and eight cycles;the planar graph resides on the urban areas in the south-east part of China.

关键词： Transport networks Unconventional computing Slime mould Bio-inspired computing Bio-cybernetics Adaptive control Intelligent transportation

A Cilia-inspired Closed-loop Sensor-actuator Array

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Journal of Bionic Engineering 2018年第3期15卷 526-532页

作者： James G. H. Whiting Richard Mayne Chris Melhuish andrew adamatzky Unconventional Computing Centre and Bristol Robotics Laboratory University of the West of England Bristol UK

Cilia are finger-like cell-surface organelles that are used by certain varieties of aquatic unicellular organisms for motility, sensing and obj ect manipulation. Initiated by internal generators and external mechanical and chemical stimuli, coordinated undulations of cilia lead to the motion of a fluid surrounding the organism. This motion transports micro-particles towards an oral cavity and provides motile force. Inspired by the emergent properties of cilia possessed by the pond organism P. caudatum, we propose a novel smart surface with closed-loop control using sensor-actuators pairings that can manipulate objects. Each vibrating motor actuator is controlled by a localised microcontroller which utilises proximity sensor information to initiate actuation. The circuit boards are designed to be plug-and-play and are infinitely up-scalable and reconfigurable. The smart surface is capable of moving objects at a speed of 7.2 millimetres per second in forward or reverse direction. Further development of this platform will include more anatomically similar biomimetic cilia and control.

关键词： bioinspiration artificial cilia object manipulation sorting platforms

Identification of Nonstationary Cellular Automata

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Journal of Computer Science & Technology 1992年第4期7卷 379-382页

作者： andrew I. adamatzky Biophysics Department Sankt-Petersburg University Universitetskaya nab 7/9 Sankt-Petersburg 199164 Russia

The principal feature of nonstationary cellular automata (NCA) is that a local transition rule of each cell is changed at each time step depending on neighborhood configuration at previous time- step The identification problem for NCA is extraction of local transition rules and the establishment of mecha- nism for changing these rules using sequence of NCA configurations. We present serial and parallel algorithms for identification of NCA.

关键词： Identification of Nonstationary Cellular Automata NCA

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A Physarum-inspired approach to supply chain network design

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Science China(Information Sciences) 2016年第5期59卷 191-204页

作者： Xiaoge ZHANG andrew adamatzky Xin-She YANG Hai YANG Sankaran MAHADEVAN Yong DENG School of Computer and Information Science Southwest University School of Engineering Vanderbilt University Unconventional Computing Center University of the West of England School of Science and Technology Middlesex University Department of Civil and Environmental Engineering the Hong Kong University of Science and Technology

A supply chain is a system which moves products from a supplier to customers, which plays a very important role in all economic activities. This paper proposes a novel algorithm for a supply chain network design inspired by biological principles of nutrients’ distribution in protoplasmic networks of slime mould Physarum polycephalum. The algorithm handles supply networks where capacity investments and product flows are decision variables, and the networks are required to satisfy product demands. Two features of the slime mould are adopted in our algorithm. The first is the continuity of flux during the iterative process, which is used in real-time updating of the costs associated with the supply links. The second feature is adaptivity. The supply chain can converge to an equilibrium state when costs are changed. Numerical examples are provided to illustrate the practicality and flexibility of the proposed method algorithm.

关键词： supply chain design Physarum capacity investments network optimization adaptivity

Evolutionary computational platform for the automatic discovery of nanocarriers for cancer treatment

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npj Computational Materials 2021年第1期7卷 1363-1374页

作者： Namid R.Stillman Igor Balaz Michail-Antisthenis Tsompanas Marina Kovacevic Sepinoud Azimi Sébastien Lafond andrew adamatzky Sabine Hauert Department of Engineering Mathematics University of BristolBristolUK Department of Cell and Developmental Biology University College LondonLondonUK Laboratory for Meteorology Physicsand BiophysicsFaculty of AgricultureUniversity of Novi SadNovi SadSerbia Unconventional Computing Laboratory University of the West of EnglandBristolUK Department of Chemistry Biochemistryand Environmental ProtectionFaculty of SciencesUniversity of Novi SadNovi SadSerbia Faculty of Science and Engineering Åbo Akademi UniversityTurkuFinland

We present the EVONANO platform for the evolution of nanomedicines with application to anti-cancer *** work aims to decrease both the time and cost required to develop nanoparticle *** includes a simulator to grow tumours,extract representative scenarios,and simulate nanoparticle transport through these scenarios in order to predict nanoparticle *** nanoparticle designs are optimised using machine learning to efficiently find the most effective anti-cancer *** demonstrate EVONANO with two examples optimising the properties of nanoparticles and treatment to selectively kill cancer cells over a range of tumour *** platform shows how in silico models that capture both tumour and tissue-scale dynamics can be combined with machine learning to optimise nanomedicine.

关键词： treatment distribution nanoparticle

On the apparent line-of-sight alignment of the peak X-ray intensity of the magnetosheath and the tangent to the magnetopause,as viewed by SMILE-SXI

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Earth and Planetary Physics 2024年第1期8卷 155-172页

作者： andrew Read Department of Physics&Astronomy University of LeicesterLeicesterLE17RHUK

The Soft X-ray Imager(SXI)on board the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)spacecraft will be able to view the Earth’s magnetosheath in soft *** images of the X-ray emission visible from the position of SMILE are created for a range of solar wind densities by using 3 years of the SMILE mission orbit,together with models of the expected X-ray emissivity from the Earth’s *** from global magnetohydrodynamic simulations and a simple model for exospheric neutral densities are used to compare the locations of the lines of sight along which integrated soft X-ray intensities peak with the lines of sight lying tangent to surfaces(defined here to be the magnetopause)along which local soft X-ray intensities peak or exhibit their strongest gradients,or both,for strongly southward interplanetary magnetic field conditions when no depletion or low-latitude boundary layers are ***,in the parameter space of the various times and seasons,orbital phases,solar wind conditions,and magnetopause models,the alignment of the X-ray emission peak with the magnetopause tangent is good,or is not,is *** main results are as *** spacecraft needs to be positioned well outside the magnetopause;low-altitude times near perigee are not *** addition,there are seasonal aspects:dayside-apogee orbits are generally very good because the spacecraft travels out sunward at high altitude,but nightside-apogee orbits,behind the Earth,are bad because the spacecraft only rarely leaves the ***-apogee and dawnapogee orbits are ***-apogee orbits worsen slightly over the first three mission years,whereas nightside-apogee orbits improve ***,many more times of good agreement with the peak-to-tangent hypothesis occur when the solar wind is in a high-density state,as opposed to a low-density *** a high-density state,the magnetopause is compressed,and the spacecraft is more often a good d

关键词： X-rays magnetosphere magnetosheath magnetopause Solar wind Magnetosphere Ionosphere Link Explorer(SMILE) Earth solar wind charge exchange

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