检索结果-南通市图书馆

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

前庭神经鞘瘤手术进展：漫长的成功之路

中国现代神经疾病杂志 2007年第6期7卷 511-514页

作者： andrei Koerbel Alireza Gharabaghi Sam Safavi-Abbasi Marcos Tatagiba Madjid Samii 刘睽（译）只达石（校） Department of Neurosurgery International Neuroscience Institute Hannover Department of Neurosurgery University Hospital of Tubingen Germany 天津市环湖医院神经外科 300060 天津医科大学总医院

20世纪前庭神经鞘瘤（vestibular schwannoma）手术疗效的显著提高伴随着神经外科的整体进展。这段历史是与前庭神经鞘瘤高病死率和高病残率艰难抗争的历史。

关键词：前庭神经鞘瘤手术进展神经外科手术疗效病残率病死率

脊髓损伤后残存自主神经功能载录国际标准：脊髓损伤患者评估的最新进展——中文版引言

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华物理医学与康复杂志 2010年第4期32卷 309-309页

作者： andrei Krassiouko 刘楠(译) 周谋望(译) 郭铁成(校) Department of Medicine University of British Columbia Vancouver Canada 不详

脊髓损伤除了造成躯体瘫痪外,还会导致自主神经系统功能障碍.美国脊柱损伤协会（ASIA）和国际脊髓协会（ISCoS）等国际组织共同制定了〈脊髓损伤后残存自主神经功能载录国际标准〉,发表于2009年第1期.经该文的通讯作者加拿大不列颠哥伦... 详细信息

脊髓损伤除了造成躯体瘫痪外,还会导致自主神经系统功能障碍.美国脊柱损伤协会（ASIA）和国际脊髓协会（ISCoS）等国际组织共同制定了〈脊髓损伤后残存自主神经功能载录国际标准〉,发表于2009年第1期.经该文的通讯作者加拿大不列颠哥伦比亚大学andrei Krassioukov教授建议,在征得了杂志主编Jean Jacques Wyndaele教授的同意后,现将此文翻译为中文. 我们刊登该标准的目的,是向广大读者提供一个国际通用的评定脊髓损伤后自主神经系统功能的工具.供大家在临床实践和研究中参考使用.

关键词：脊髓损伤患者自主神经功能国际标准自主神经系统功能障碍中文残存评估哥伦比亚大学

Thymidine Glycol: The Effect on DNA Structure and DNA Binding by Site-Specific Proteins

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Natural Science 2015年第11期7卷 491-509页

作者： Elena A. Kubareva Fan Yang Alexandra Yu. Ryazanova Nina G. Dolinnaya andrei V. Golovin Nikolai V. Molochkov Elena A. Romanova Elizaveta A. Karpova Timofei S. Zatsepin Tatiana S. Oretskaya Belozersky Institute of Physico-Chemical Biology Lomonosov Moscow State University Moscow Russia Chemistry Department Lomonosov Moscow State University Moscow Russia Faculty of Bioengineering and Bioinformatics Lomonosov Moscow State University Moscow Russia Institute of Theoretical and Experimental Biophysics Russian Academy of Science Moscow Region Pushchino Russia

Thymidine glycol (5,6-dihydroxy-5,6-dihydrothymidine, Tg) is a major type of oxidative damage in DNA. During chemical oligonucleotide synthesis, Tg residue was incorporated in the different positions of 17 b.p. DNA duplexes, which differ in one base pair in the internal part. According to UV-melting curves, Tg destabilizes the double helix in a sequence independent manner. In contrast, the localized alterations in duplex structure were shown by CD spectroscopy to depend on the type of base pairs flanking the Tg lesion. Molecular dynamics simulations demonstrate that Tg is partially out of the double helix. For the first time, Tg impact on several site-specific DNA-binding proteins is studied, namely p50 and p65 subunits of nuclear factor kappa-B (NF-κB) and DNA methyltransferase SsoII (***). Our results show that p50/p50 and p65/p65 homodimers of NF-κB can tolerate a single Tg residue in the binding site quite well. Nevertheless the homodimers have different affinities to the oxidized κB site depending on the Tg position. *** can act as a transcription repressor when bound to the regulatory site. *** demonstrates decreased affinity and lowered methylation efficiency when its methylation site contains Tg in the central position. Single Tg in one half of the regulatory site decreases *** affinity to the oxidized DNA, whereas Tg presence in both half-sites prevents *** binding to such ligand.

关键词： Thymidine Glycol Oxidative Damage Molecular Dynamics Simulations Nuclear Factor Kappa-B DNA Methyltransferase SsoII

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

掠夺之手

From Uncle Sam to Just Trump: A long Way of Alternating Irony- hate-ambivalence among Russian Users-Students Regarding Politicians

作者： (美)安德烈·施莱弗(andrei Shleifer) (美)罗伯特·维什尼(Robert W. Vishny)

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Macro Management & Public Policies 2020年第2期2卷 7-11页

作者： andrei Ulianovskii Dobrova Tatiana Olga Filatova Vadim Golubev St.Petersburg State University Universitetskaya nab 7/9

The paper is discusses the role of emotionally significant political images in youth *** study covers the period between 2006 and 2017 during which Russia saw not only a political and economic transition but also dramatic changes in communication *** 6-stage research included two waves of testing in 2006,2012,*** were aged 17 to 24 years *** 2017 the general youth international value agenda can be considered formed,with its essential feature being the further reduction of the influence of advertising and communication of politicians’brands.

关键词： Russia America Youth Imaginary characters Values Heroes Antiheroes Сultural studies Political culture Social media Online shows

Comparison of Three Methods of Regional Anesthesia of Peripheral Nerves and Plexuses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Online Content Impact on Young people’s Values Transformation

Open Journal of Anesthesiology（麻醉学期刊） 2012年第5期

作者： Valery Piacherski Aliaksei Marochkov andrei Brukhnou Zakhar Kokhan

来源：评论

学校读者我要写书评

暂无评论

Macro Management & Public Policies 2020年第1期2卷 33-44页

作者： andrei Ulianovskii Dobrova Tatiana Olga Filatova Vadim Golubev St.Petersburg State University Universitetskaya nab 7/9

The investigation that underpins the present article interprets the gaps of the social data *** is designed to select a set of images from the“media noise”of the information society,and then describe those that characterize the visual conceptualization of the *** authors present the results of their 14-year research based on the original research methodology,and carried out in several stages(2006,2012,2017).The study is called“Fictional creatures of the mass media ***,21 century”.In 2017,it is assumed that the overall youth international value agenda,an essential feature of which is the further reduction of the impact of advertising and brand communications,has been *** data are given in the article.

关键词： Online content Social media Youth values E-values E-society Imaginary character Internet Mass media Content analysis Social-demographic analysis Rough statistical analysis Deep axiological analysis

分子导体(ET)2(H3O)(CH3PhSO3)2(H20)5中H3O+的精确测定和意义

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

分子导体(ET)2(H3O)(CH3PhSO3)2(H20)5中H3O+的精确测定和意义

Progression of Cognitive Deficit in Older People with Mild Cognitive Impairment Treated with Cerebrolysin

全国第八届有机固体电子过程暨华人有机光电功能材料学术讨论会

作者：方奇陈红余陈红凤 Batsanov,andrei.S. Howard,Judith.A.K. 山东大学晶体材料国家重点实验室 Department of Chemistry University of DurhamDH1 3LEEngland

我们在2004报道了一种基于ET的分子导体,化学式写为(ET)(CHPhSO)(HO),晶胞不对称单位中含两个化学式,合并为(ET)(CHPhSO)(HO)。后来,我们对上述化学式产生疑问。电子给体ET在其电荷转移盐中电荷取+1的情况很少;另一方面,该化合物中ET的...

我们在2004报道了一种基于ET的分子导体,化学式写为(ET)(CHPhSO)(HO),晶胞不对称单位中含两个化学式,合并为(ET)(CHPhSO)(HO)。后来,我们对上述化学式产生疑问。电子给体ET在其电荷转移盐中电荷取+1的情况很少;另一方面,该化合物中ET的键参数非常接近于晶体结构数据库中ET+0.5的统计平均值。若假设一个HO质子

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Health 2014年第19期6卷 2581-2591页

作者： Irina S. Boksha Svetlana I. Gavrilova Igor V. Kolykhalov Iana B. Fedorova Iaroslav B. Kalyn Natalia D. Selezneva andrei V. Samorodov Serge N. Miasoedov Elizabeta B. Mukaetova-ladinska laboratory of Neurochemistry Moscow Russia Department of Alzheimer’s Disease and Related Disorders Moscow Russia Department of Bioengineering and Medical Equipment and Systems Moscow State Technical University Moscow Russia laboratory of Biostatistics and Evidence Based Medicine Mental Health Research Center of Russian Academy of Medical Sciences Moscow Russia Institute of Neurocience Newcastle University Institute for Ageing Newcastle University Campus for Ageing and Vitality Newcastle upon Tyne UK

Objectives: Although people with amnestic mild cognitive impairment (aMCI) benefit from cerebrolysin treatment, some still develop dementia. The aim of the current study was to identify most informative clinical assessment tests to predict the therapy efficacy in aMCI subjects treated with cerebrolysin. Methods: We studied patients with amnestic mild cognitive impairment (aMCI;n = 53) who had regular neurocognitive and clinical psychiatric assessments and were treated with cerebrolysin i.v. infusions 20 × 30 ml twice a year over three years period. Data were analyzed using non-parametric statistics, cluster and linear discriminant analyses. Results: Combined mathematical modeling enabled to predict cognitive decline from aMCI to dementia in the cerebrolysin-treated patients based on their initial neurocognitive assessment scores. We identified a “dementia risk group” with fast cognitive decline (i.e. low efficacy of the treatment). lower baseline scores in the Mattis Dementia Rating Scale Memory subtest, Mini-Mental State Examination (MMSE), 10 word list immediate recall, and Frontal Assessment Battery tests when accompanied by higher depression score (Hamilton Depression Rating Scale) suggest poor prognosis for aMCI patients treated with cerebrolysin. Changes in scores on the MMSE, Boston naming test, Digit span forward, and Wechsler scale subtest “Categorical associations” during the treatment course are more characteristic for patients who convert to dementia than their initial scores. Conclusions: aMCI subjects treated with cerebrolysin with lower baseline cognitive functioning and subclinical depression have poor prognosis in terms of converting to dementia. Changes in the MMSE, Boston naming test, Digit span forward, and Wechsler scale subtest “Categorical associations” scores during the treatment course are more informative to identify patients who will develop dementia than their initial scores.

关键词： Mild Cognitive Impairment Cerebrolysin Dementia Cluster Analysis linear Discriminant Analysis