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A fixed point theorem for Proinov mappings with a contractive iterate

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Applied Mathematics(A Journal of Chinese Universities) 2023年第3期38卷 403-412页

作者： Erdal Karapnar andreea Fulga Department of Medical Research China Medical UniversityTaichungTaiwanChina Department of Mathematics Cankaya University06790EtimesgutAnkaraTurkey Department of Mathematics and Computer Science Transilvania University of BrasovBrasovRo-mania.

In this paper,we consider the fixed point theorem for Proinov mappings with a contractive iterate at a *** other words,we combine and unify the basic approaches of Proinov and Sehgal in the framework of the complete m... 详细信息

关键词： contractive iterate at a point Proinov mappings fixed point theorems

A new non-linear vortex lattice method:Applications to wing aerodynamic optimizations

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Chinese Journal of Aeronautics 2016年第5期29卷 1178-1195页

作者： Oliviu Sugar Gabor andreea Koreanschi Ruxandra Mihaela Botez LARCASE Laboratory of Applied Research in Active Controls Avionics and Aeroservoelasticity cole de Technologie Supérieure

This paper presents a new non-linear formulation of the classical Vortex Lattice Method （VLM） approach for calculating the aerodynamic properties of lifting surfaces. The method accounts for the effects of viscosity, and due to its low computational cost, it represents a very good tool to perform rapid and accurate wing design and optimization procedures. The mathematical model is constructed by using two-dimensional viscous analyses of the wing span-wise sections, according to strip theory, and then coupling the strip viscous forces with the forces generated by the vortex rings distributed on the wing camber surface, calculated with a fully three-dimensional vortex lifting law. The numerical results obtained with the proposed method are validated with experimental data and show good agreement in predicting both the lift and pitching moment, as well as in predicting the wing drag. The method is applied to modifying the wing of an Unmanned Aerial System to increase its aerodynamic efficiency and to calculate the drag reductions obtained by an upper surface morphing technique for an adaptable regional aircraft wing.

关键词： Aerodynamic design Aerodynamic optimization Enhanced potential method Morphing wing Nonlinear vortex latticemethod Quasi-3D aerodynamic method UAS optimization

Tunneling of Relativistic Bosons Induced by Magnetic Fields in the Magnetar’s Crust

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Chinese Physics Letters 2015年第10期32卷 26-29页

作者： Marina-Aura Dariescu Ciprian Dariescu Denisa-andreea Mihu Faculty of Physics Alexandru Ioan Cuza University of Iasi Bd

The present work is devoted to the study of bosons evolving in the frozen magnetar＇s crust endowed with an ultra-strong magnetic field orthogonal to an electric field, both described by periodic functions. We discuss the quantum tunneling process through the one-dimensional potential barrier along Oz. The solutions to the Klein- Gordon equation are expressed in terms of Mathieu＇s functions which, for computable particle＇s energy range, are turning from oscillatory to exponentially growing modes along Oz. Within the Jeffreys Wentzel Kramers- Brillouin framework, the transmission coefficient is computed for the particle momentum in the middle of the instability range.

关键词： Tunneling of Relativistic Bosons Induced by Magnetic Fields in the Magnetar’s Crust

Tyrosyl radical in haemoglobin and haptoglobin-haemoglobin complex:how does haptoglobin make haemoglobin less toxic?

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The Journal of Biomedical Research 2020年第4期34卷 281-291页

作者： Dimitri A.Svistunenko andreea Manole Biomedical EPR Facility School ofLife SciencesUniversity of EssexColchesterEssex CO43SQUK Laboratory of Genetics The Salk Institute for Biological StudiesLa JollaCA 92037USA.

One of the difficulties in creating a blood substitute on the basis of human haemoglobin(Hb) is the toxic nature of Hb when it is outside the safe environment of the red blood *** plasma protein haptoglobin(Hp) takes care of the Hb physiologically leaked into the plasma-it binds Hb and makes it much less toxic while retaining the Hb’s high oxygen transporting *** used Electron Paramagnetic Resonance(EPR) spectroscopy to show that the protein bound radical induced by H2O2 in Hb and Hp-Hb complex is formed on the same tyrosine residue(s),but,in the complex,the radical is found in a more hydrophobic environment and decays slower than in unbound Hb,thus mitigating its oxidative *** data obtained in this study might set new directions in engineering blood substitutes for transfusion that would have the oxygen transporting efficiency typical of Hb,but which would be non-toxic.

关键词： blood substitute EPR haemoglobin toxicity haptoglobin HBOC protein-bound radical TRSSA

Electrocardiographic measures of repolarization dispersion and their relationships with echocardiographic indices of ventricular remodeling and premature ventricular beats in hypertension

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Journal of Geriatric Cardiology 2017年第12期14卷 717-724页

作者： Ana Ciobanu Gary Tse Tong Liu Maria V Deaconu Gabriela S Gheorghe Adriana M iliesiu Ioan T Nanea Department of Internal Medicine and Cardiology Theodor Burghele Clinical Hospital Carol Davila University of Medicine and Pharmacy Bucharest Romania Department of Medicine and Therapeutics Faculty of Medicine Chinese University of Hong Kong Hong Kong China Li Ka Shing Institute of Health Sci- ences Faculty of Medicine Chinese University of Hong Kong Hong Kong China Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease Department of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin China

Objective To examine the relationship between Tpeak- Tend interval （Tpe） and Tpe/QT ratio with occurrence of ventricular premature beats （VPBs） and left ventricular remodeling in hypertension. Methods A total of 52 patients with mild to moderate essential hypertension were included, undergoing echocardiography and 24-hours Holter monitoring. Ventricular remodeling was assessed by left ventricular mass index （LVMI） using the Devereux formula and diastolic fimction by transmitral E and A wave velocities and E/A ratio. Tpe was measured in the precordial leads. The end of the T wave was set by the method of the tangent to the steepest descending slope of the T wave. Results Tpe and Tpe/QT in leads V2 （r = 0.33, P = 0.01; r = 0.27, P = 0.04 respectively） and V3 （r = 0.40, P = 0.002; r = 0.40, P = 0.003, respectively） correlated significantly with LVMI. A significant inverse relationship was observed between E/A ratio and QT （r = -0.33, P = 0.01）, Tpe in V3 （r = -0.39, P = 0.003） and Tpe/QT in V3 （r = -0.31, P = 0.02）. Tpe in V3, V5, mean Tpe and maximum Tpe with cut-offvalues of 60 ms, 59 ms, 62 ms and 71 ms, respectively, associated with the occurrence of ventricular premature beats. Conclusions The repolarization parameters Tpe interval and Tpe/QT ratio correlate with LVMI and indices of left ventricular diastolic function and show better predictive values than traditional parameters such as QT interval and QT dispersion. Lead V3 is the best lead for measuring Tpe and Tpe/QT. These ECG indices can therefore be used in clinical practice to monitor LV remodeling and predict occurrence of VPBs.

关键词： Hypertension Repolarization Tpeak-Tend Ventricular remodeling

Characterization of Malalignment between Atrial and Ventricular Septa in Overriding/Straddling Tricuspid and Mitral Valves

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Congenital Heart Disease 2021年第1期16卷 1-16页

作者： Mika Saito Dragulescu andreea Shi-Joon Yoo The Labatt Family Heart Centre The Hospital for Sick ChildrenUniversity of TorontoTorontoCanada Division of Cardiology Department of PaediatricsThe Hospital for Sick ChildrenUniversity of TorontoTorontoCanada Department of Diagnostic Imaging The Hospital for Sick ChildrenUniversity of TorontoTorontoCanada

Objective:Overriding/straddling of an atrioventricular valve is a consequence of atrial-ventricular septal *** sought to characterize the malalignment by analogizing it to a flap-door and using structured ***:The echocardiograms and magnetic resonance images of 35 patients with overriding/straddling tricuspid or mitral valve were evaluated to assess the following modifiers;the malaligned part of the septum,the reference structure,and the mechanism,direction and severity of ***:The pathology included classic overriding tricuspid valve in 15,classic overriding mitral valve in 12,and overriding tricuspid valve with left juxtaposition of atrial appendages in *** classic overriding tricuspid valve,the ventricular septum was hinged to the anterior interventricular groove and its insertion to the posterior interventricular groove was displaced toward the right *** VSD primarily involved the inlet but also extended toward the anterior interventricular *** classic overriding mitral valve,the ventricular septum was hinged to the posterior interventricular groove and crux *** insertion to the anterior interventricular groove was displaced toward the left *** VSD primarily involved the anterior part but also extended toward the *** tricuspid valve with left juxtaposition of atrial appendages had a mild degree of malalignment with displacement/rotation of the atrioventricular *** spaced short-axis images were most helpful in characterizing the ***:Overriding/straddling atrioventricular valves can be easily understood by analogizing the atrial-ventricular septal malalignment to a flap-door and describing the pathology in a structured *** to what has previously been known,the VSD is not limited to the inlet or outlet part of the ventricular septum.

关键词： Malalignment ventricular septal defect overriding straddling tricuspid mitral

Uncoupling protein 2 deficiency reduces proliferative capacity of murine pancreatic stellate cells

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Hepatobiliary & Pancreatic Diseases International 2016年第6期15卷 647-654页

作者： Sarah Muller Sandra Maria Klingbeil andreea Sandica Robert Jaster Department of Medicine II Division of Gastroen-terologyRostock University Medical CenterE.-Heydemann-Str.618057 RostockGermany

BACKGROUND： Uncoupling protein 2 （UCP2） has been suggested to inhibit mitochondrial production of reactive oxygen species （ROS） by decreasing the mitochondrial membrane potential. Experimental acute pancreatitis is associated with increased UCP2 expression, whereas UCP2 deficiency retards regeneration of aged mice from acute pancreatitis. Here, we have addressed biological and molecular functions of UCP2 in pancreatic stellate cells （PSCs）, which are involved in pancreatic wound repair and fibrogenesis. METHODS： PSCs were isolated from 12 months old （aged） UCP2^-/- mice and animals of the wild-type （WT） strain C57BL/6. Proliferation and cell death were assessed by em- ploying trypan blue staining and a 5-bromo-2＇-deoxyuridine incorporation assay. Intracellular fat droplets were visualized by oil red O staining. Levels of mRNA were determined by RT-PCR, while protein expression was analyzed by immunoblotting and immunofluorescence analysis. Intracellular ROS levels were measured with 2＇,7＇-dichlorofluorescin diacetate. Expression of senescence-associated β-galactosidase （SA β-Gal） was used as a surrogate marker of cellular senescence. RESULTS： PSCs derived from UCP2^-/- mice proliferated at a lower rate than cells from WT mice. In agreement with this observation, the UCP2 inhibitor genipin displayed dose- dependent inhibitory effects on WT PSC growth. Interestingly, ROS levels in PSCs did not differ between the two strains, and PSCs derived from UCP2^-/- mice did not senesce faster than those from corresponding WT cells. PSCs from UCP2^-/- mice and WT animals were also indistinguishable with respect to the activation-dependent loss of intracellular fat droplets, expression of the activation marker α-smooth muscle actin, type I collagen and the autocrine/paracrine mediators interleukin-6 and transforming growth factor-I~ 1. CONCLUSIONS： A reduced proliferative capacity of PSC from aged UCP2^-/- mice may contribute to the retarded regeneration after acute pancreatitis.

关键词： pancreatitis proliferation stellate cell biology uncoupling protein 2

Kinetics and thermodynamics modeling of Nd(Ⅲ) removal from aqueous solution using modified Amberlite XAD7

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Journal of Rare Earths 2020年第3期38卷 306-314页

作者： Petru Negrea andreea Gabor Corneliu Mircea Davidescu Mihaela Ciopec Adina Negrea Narcis Duteanu Politehnica University of Timisoara Faculty of Industrial Chemistry and Environmental Engineering 2 Piata Victoriei RO 300006 Timisoara Romania

New adso rbent material was obtained by modification of commercial Amberlite XAD7 with thiourea that represents a non-toxic,cheap and environmentally friendly *** adsorbent was used for removal of neodymium ions from aqueous *** modified Amberlite involved in this study shows good adsorption capacities(74.3 mg/g) and excellent efficiency during Nd removal *** order to elucidate the mechanism of the Nd adsorption process kinetic,thermodynamic and equilibrium studies were performed,establishing this way which kinetic model better describes the Nd adsorption *** the thermodynamic studies prove that the Nd adsorption on thiourea modified Amberlite XAD7 is an endothermic and spontaneous process.

关键词： Neodymium Amberlite XAD7 Adsorption mechanism Adsorption isotherm Thiourea Rare earths

MEDICALLY ASSISTED HUMAN REPRODUCTIVE TECHNOLOGIES （ART） AND HUMAN RIGHTS -- THE EUROPEAN PERSPECTIVE

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Frontiers of Law in China-Selected Publications from Chinese Universities 2016年第2期11卷 339-369页

作者： Elisabeth Sterner andreea Maria Rosu Bucharest Bar Association Romania

The present article examines how the progress of science, and in particular, medically assisted human reproductive technologies （ART） have provoked a revolution in the sphere of family relations, generating a series of ethical and legal conflicts. The article focuses on the European perspective, without ignoring the international sphere, given the globalization of the phenomenon. The emerging legal issues are analyzed through the filter of international human rights, not only an important aspect to take into consideration in the context of bioethics in general, but a ＂passage obligO＂ given that certain concepts find their explanation and coordinates in international human rights law. It is from this perspective that the relationship between ART and human rights is presented. The applicable international and European legal instruments and principles shall be mentioned, as well as a brief comparison of national legal frameworks in Europe The emerging bioethical and legal issues are examined in correlation with the response of the European Court of Human Rights through its case law aimed at balancing conflicting rights when faced with issues pertaining to ART. Lastly, the article presents in more detail the particular legal issues under debate in France and Italy, two European countries with specific legislation in the field.

关键词： human rights bioethics European Convention on Human Rights surrogacy