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Promising psyllium-based composite containing TiO2 nanoparticles as aspirin-carrier matrix

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Progress in Natural Science:Materials International 2014年第3期24卷 205-209页

作者： Marcela-Corina rosu Ioan Bratu National Institute for Research and Development of Isotopic and Molecular Technologies

Composite nanomaterials represent a new trend in the biomedical field. Coupling inorganic/organic constituents with non-toxicity/biocompatibility properties leads to develop the new systems having special characteristics that can be used in various bio-applications. This paper describes the preparation and characterization of psyllium-based composites containing TiO2 nanoparticles in order to develop new therapeutic strategies for aspirin drug delivery. The structural characteristics of obtained materials were investigated by FTIR spectroscopy. The UV–vis spectrophotometric analysis was performed to evaluate the aspirin release behavior under different pH conditions at 37 1C. Combining psyllium(as an excellent source of fiber) with TiO2 inorganic unit(as vehicle of aspirin) it was found that polymeric-TiO2networks have promising potential for controlled aspirin release as therapeutic agent.

关键词： Psyllium Titanium dioxide Aspirin In vitro release

Cost of treatment support for multidrug-resistant tuberculosis using patient-centred approaches in Ethiopia: a model-based method

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Infectious Diseases of Poverty 2023年第4期12卷 54-62页

作者： Laura rosu Lucy Morgan Ewan M.Tomeny Claire Worthington Mengdi Jin Jasper Nidoi David Worthington Liverpool School of Tropical Medicine Pembroke PlaceLiverpoolL35QAUK Management Science Lancaster UniversityLancasterUK Makerere University Lung Institute KampalaUganda

Background Patient and health system costs for treating multidrug-resistant tuberculosis (MDR-TB) remain high even after treatment duration was shortened. Many patients do not finish treatment, contributing to increased transmission and antimicrobial resistance. A restructure of health services, that is more patient-centred has the potential to reduce costs and increase trust and patient satisfaction. The aim of the study is to investigate how costs would change in the delivery of MDR-TB care in Ethiopia under patient-centred and hybrid approaches compared to the current *** We used published data, collected from 2017 to 2020 as part of the Standard Treatment Regimen of Anti-Tuberculosis Drugs for Patients with MDR-TB (STREAM) trial, to populate a discrete event simulation (DES) model. The model was developed to represent the key characteristics of patients’ clinical pathways following each of the three treatment delivery strategies. To the pathways of 1000 patients generated by the DES model we applied relevant patient cost data derived from the STREAM trial. Costs are calculated for treating patients using a 9-month MDR-TB treatment and are presented in 2021 United States dollars (USD).Results The patient-centred and hybrid strategies are less costly than the standard-of-care, from both a health system (by USD 219 for patient-centred and USD 276 for the hybrid strategy) and patient perspective when patients do not have a guardian (by USD 389 for patient-centred and USD 152 for the hybrid strategy). Changes in indirect costs, staff costs, transport costs, inpatient stay costs or changes in directly-observed-treatment frequency or hospitalisation duration for standard-of-care did not change our *** Our findings show that patient-centred and hybrid strategies for delivering MDR-TB treatment cost less than standard-of-care and provide critical evidence that there is scope for such strategies to be implemented in routine care. These

关键词： Affordability Multidrug-resistant tuberculosis Directly-observed treatment Patient-centred approach Tuberculosis treatment delivery

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Influence of Relative Electrode-Electrolyte Movement over Productivity for Silver Recovery from Diluted Solutions

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Journal of Chemistry and Chemical Engineering 2011年第4期5卷 296-304页

作者： Mirela Ioana Iorga Marius Constantin Mirica Ionel Balcu Nicolae Mirica Dan rosu Department of Applied Electrochemistry National Institute of R＆D in Electrochemistry and Condensed Matter-INCEMC-Timisoara Timisoara 300569 Romania

The paper presents the influence of relative electrode-electrolyte movement over productivity for silver ions recovery by electrodeposition from diluted solutions. Wasted photographic fixing agent solution in various concentrations was used. For each concentration three regimes were studied： stationary, electrode rotation with 100 rpm and electrode rotation with 300 rpm. Polarization curves were drawn and working conditions from silver recovery point of view were discussed.

关键词： Metal recovery relative electrode-electrolyte movement electrodeposition mass transport overpotential rotating electrode

如何全模拟控制的降压和升压转换器实现输出稳压

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今日电子 2017年第1期 57-59页

作者： Mihnea rosu Microchip公司

可使用同一款单片机实现纯模拟控制的同步降压型电源和升压型电源。从而实现输出稳压。两种方案拥有一个共同的优点,即不占用任何处理器资源,这样内核就可以全力满足更为复杂的固件的需求。同时,模拟回路能够更快速地响应负载阶跃和输... 详细信息

可使用同一款单片机实现纯模拟控制的同步降压型电源和升压型电源。从而实现输出稳压。两种方案拥有一个共同的优点,即不占用任何处理器资源,这样内核就可以全力满足更为复杂的固件的需求。同时,模拟回路能够更快速地响应负载阶跃和输入电压变化,这对于不少应用而言是非常有用的。

关键词：模拟控制输出稳压降压型升压转换器电压变化升压型单片机处理器

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Unusual Quadruplex:Tri-G-quadruplex and Double-quadruplex

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Unusual Quadruplex:Tri-G-quadruplex and Double-quadruplex

第八届全国化学生物学学术会议

作者： Jun Zhou Samir Amrane Anne Bourdoncle Frederic rosu Valerie Gabelica Jean-Louis Mergny Universite de Bordeaux Laboratoire ARNAF-33000 Bordeaux and INSERMU869Institut Europeen de Chimie et BiologieF-33600 PessacFrance.

＜正＞Guanine-rich oligonucleotides being able to self-associate to form G-quadruplex, However,all the G-quadruplex structures investigated to date are formed by one,two and four G-rich ***,an important question remains unanswered:can G-quadruplex structures be formed by three strands,leading to a tri-G-quadruplex species? Interestingly,cytosine-rich sequence,the complementary of G-rich strand can form another quadruplex structure,i-motif,at acidic condition.

关键词： G-quadruplex i-motif

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罗马尼亚不同沙棘品种叶中甘树脂的提取

国际沙棘研究与开发 2010年第3期8卷 45-48页

作者： maria Magdalena Zamfirache Zenovia Olteanu Elena Truta Stefania Surdu Lacramioara Oprica Ioan Viorel Rati Ciprian Manzu Gurau Milian Craita rosu Titu Zamfirache 梁月 Alexandru Ioan Cuza "University Faculty of Biology Biological Research Institute of Iasi Bacau university Faculty of Biology Alexandru Ioan Cuza"University Faculty of Geography and Geology 水利部水土保持植物开发管理中心北京100038

沙棘(Hippophae rhamnoides)是一种可广泛生长于欧亚地区,包括罗马尼亚的小果实灌木。沙棘具有药用及营养价值,同时可以改善区域的微气候环境。人们已经研究了罗马尼亚沙棘的生物化学组分及相关数据,所以我们分析了不同沙棘叶的甘树脂,... 详细信息

沙棘(Hippophae rhamnoides)是一种可广泛生长于欧亚地区,包括罗马尼亚的小果实灌木。沙棘具有药用及营养价值,同时可以改善区域的微气候环境。人们已经研究了罗马尼亚沙棘的生物化学组分及相关数据,所以我们分析了不同沙棘叶的甘树脂,一个重要的生化参数可以为植株的一项基本新陈代谢——光合作用提供信息。结果表明根据品种及特定环境因素的不同,产生了多样性。

关键词：沙棘品种叶片甘树脂提取叶绿素A 叶绿素B 胡萝卜素

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