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蓝区无机薄膜电致发光材料研究进展

中国光学 2017年第1期10卷 13-24页

作者：王小平宁仁敏王丽军柯小龙陈海将宋明丽刘凌鸿上海理工大学理学院上海200093

介绍了蓝区无机薄膜电致发光材料的应用、电致发光器件的发光原理及结构类型,综述了蓝区无机薄膜电致发光材料的种类及其各自存在的问题,重点概述了已实用化的蓝区无机电致发光材料Ga N的研究及应用现状。由于目前多数蓝光芯片核心技术... 详细信息

介绍了蓝区无机薄膜电致发光材料的应用、电致发光器件的发光原理及结构类型,综述了蓝区无机薄膜电致发光材料的种类及其各自存在的问题,重点概述了已实用化的蓝区无机电致发光材料Ga N的研究及应用现状。由于目前多数蓝光芯片核心技术被少数国外公司垄断,我国所掌握的技术离世界先进水平仍有相当大的差距,因此迫切需要国内能够加大对蓝区电致发光材料的研发。

关键词：蓝光材料 LED TFEL GaN

Glutamatergic CYLD deletion leads to aberrant excitatory activity in the basolateral amygdala:association with enhanced cued fear expression

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Neural Regeneration Research 2025年第11期20卷 3259-3272页

作者： Huidong Li Faqin Li Zhaoyi chen Erwen Wu xiaoxi Dai Danni Li Haojie An Shiyi Zeng Chunyan Wang Li Yang cheng long School of Life Sciences South China Normal UniversityGuangzhouGuangdong ProvinceChina School of Life Sciences Guangzhou UniversityGuangzhouGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Major Obstetric Diseases The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina South China Normal University-Panyu Central Hospital Joint Laboratory of Translational Medical Research Panyu Central HospitalGuangzhouGuangdong ProvinceChina

Neuronal activity,synaptic transmission,and molecular changes in the basolateral amygdala play critical roles in fear ***(CYLD)is a deubiquitinase that negatively regulates the nuclear factor kappa-B *** is well studied in non-neuronal cells,yet underinvestigated in the brain,where it is highly *** studies have shown involvement of CYLD in the remodeling of glutamatergic synapses,neuroinflammation,fear memory,and anxiety-and autism-like ***,the precise role of CYLD in glutamatergic neurons is largely ***,we first proposed involvement of CYLD in cued fear *** next constructed transgenic model mice with specific deletion of Cyld from glutamatergic *** results show that glutamatergic CYLD deficiency exaggerated the expression of cued fear in only male ***,loss of CYLD in glutamatergic neurons resulted in enhanced neuronal activation,impaired excitatory synaptic transmission,and altered levels of glutamate receptors accompanied by over-activation of microglia in the basolateral amygdala of male ***,our study suggests a critical role of glutamatergic CYLD in maintaining normal neuronal,synaptic,and microglial *** may contribute,at least in part,to cued fear expression.

关键词： basolateral amygdala cued fear expression cylindromatosis deubiquitinase glutamate receptor 1 glutamatergic neuron microglial activation N-methyl-D-aspartate receptor 1 neuronal activation synaptic transmission

不同切口超声乳化白内障吸除术联合小梁切除术的疗效和耐受性的荟萃分析(英文)

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国际眼科杂志 2010年第9期10卷 1645-1649页

作者：刘鹤南李迅聂庆珠陈晓隆中国医科大学附属盛京医院眼科中国辽宁省沈阳市110004

目的:评价并比较一切口和二切口超声乳化白内障吸除术联合小梁切除术治疗白内障合并青光眼的疗效和耐受性。方法:按照Cochrane协作网方法全面检索符合纳入标准的比较一切口和二切口超声乳化白内障吸除术联合小梁切除术的临床对照研究,... 详细信息

目的:评价并比较一切口和二切口超声乳化白内障吸除术联合小梁切除术治疗白内障合并青光眼的疗效和耐受性。方法:按照Cochrane协作网方法全面检索符合纳入标准的比较一切口和二切口超声乳化白内障吸除术联合小梁切除术的临床对照研究,将其进行荟萃分析。临床疗效的评估包括:眼压下降百分比采用标准化均差(SMD),术后最佳矫正视力≥0.5的患者百分比采用比值比(OR),手术成功率采用相对危险度(RR)。临床耐受性的评估采用RR。所有结果均以95%可信区间表示。数据分析采用Stata10.1。结果:降低眼压的临床疗效二切口术式明显优于一切口术式,差异具有统计学意义(SMD,-0.19;95%CI,-0.33到-0.04;P=0.01);术后最佳矫正视力≥0.5的患者百分比二切口术式大于一切口术式,但差异不具有统计学意义(OR,0.65;95%CI,0.30到1.39;P=0.26);术后不加用抗青光眼药物达到靶眼压的患者百分比二切口术式大于一切口术式,但差异不具有统计学意义(RR,0.94;95%CI,0.84到1.04;P=0.22);两种术式在术后并发症方面差别无统计学意义。结论:二切口超声乳化白内障吸除术联合小梁切除术临床疗效优于一切口术式。两种术式的术后并发症没有明显差异。

关键词：超声乳化白内障吸除术联合小梁切除术一切口二切口荟萃分析

Genes and proteins expressed at different life cycle stages in the model protist Euplotes vannus revealed by both transcriptomic and proteomic approaches

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Science China Life Sciences 2025年第1期 232-248页

作者： Yaohan Jiang xiao chen Chundi Wang Liping Lyu Saleh A.Al-Farraj Naomi A.Stover Feng Gao Key Laboratory of Evolution & Marine Biodiversity (Ministry of Education) and Institute of Evolution & Marine Biodiversity Ocean University of China Marine College Shandong University Zoology Department College of ScienceKing Saud University Department of Biology Bradley University Laboratory for Marine Biology and Biotechnology Qingdao Marine Science and Technology Center

Sexual reproduction first appeared in unicellular protists and has continued to be an essential biological process in almost all *** protists, which contain both germline and somatic genomes within a single cell, have evolved a special form of sexual reproduction called conjugation that involves mitosis, meiosis, fertilization, nuclear differentiation, genome rearrangement, and the development of unique cellular structures. The molecular basis and mechanisms of conjugation vary dramatically among ciliates, and many details of the process and its regulation are still largely unknown. In order to better comprehend these processes and mechanisms from an evolutionary perspective, this study provides the first comprehensive overview of the transcriptome and proteome profiles during the entire life cycle of the newly-established marine model ciliate Euplotes vannus. Transcriptome analyses from 14 life cycle stages(three vegetative stages and 11 sexual stages) revealed over 26,000 genes that are specifically expressed at different stages, many of which are related to DNA replication,transcription, translation, mitosis, meiosis, nuclear differentiation, and/or genome rearrangement. Quantitative proteomic analyses identified 338 proteins with homologs associated with conjugation and/or somatic nuclear development in other ciliates, including dicer-like proteins, Hsp90 proteins, RNA polymerase Ⅱ and transcription elongation factors, ribosomal-associated proteins, and ubiquitin-related proteins. Four of these homologs belong to the PIWI family, each with different expression patterns identified and confirmed by RT-qPCR,which may function in small RNA-mediated genome rearrangement. Proteins involved in the nonhomologous end-joining pathway are induced early during meiosis and accumulate in the developing new somatic nucleus, where more than 80% of the germline sequences are eliminated from the somatic genome. A number of new candidate genes and proteins likely t

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Graphene Aerogel Composites with Self‑Organized Nanowires‑Packed Honeycomb Structure for Highly Efficient Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第2期17卷 533-547页

作者： xiao You Huiying Ouyang Ruixiang Deng Qiuqi Zhang Zhenzhong Xing xiaowu chen Qingliang Shan Jinshan Yang Shaoming Dong State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Key Laboratory of Inorganic Coating Materials CAS Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Structural Ceramics and Composites Engineering Research Center Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049People’s Republic of China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210People’s Republic of China School of Materials Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China University of Chinese Academy of Sciences Beijing 100039People’s Republic of China

With vigorous developments in nanotechnology,the elaborate regulation of microstructure shows attractive potential in the design of electromagnetic wave ***,a hierarchical porous structure and composite heterogeneous interface are constructed successfully to optimize the electromagnetic loss *** macro–micro-synergistic graphene aerogel formed by the ice template‑assisted 3D printing strategy is cut by silicon carbide nanowires(SiC_(nws))grown in situ,while boron nitride(BN)interfacial structure is introduced on graphene *** unique composite structure forces multiple scattering of incident EMWs,ensuring the combined effects of interfacial polarization,conduction networks,and magnetic-dielectric ***,the as-prepared composites present a minimum reflection loss value of−37.8 dB and a wide effective absorption bandwidth(EAB)of 9.2 GHz(from 8.8 to 18.0 GHz)at 2.5 ***,relying on the intrinsic high-temperature resistance of SiC_(nws) and BN,the EAB also remains above 5.0 GHz after annealing in air environment at 600℃ for 10 h.

关键词： Hierarchical porous structure Interface High-temperature resistance Graphene aerogel composites Electromagnetic wave absorption

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干细胞治疗慢加急性肝衰竭相关基因研究进展

中国普外基础与临床杂志 2016年第10期23卷 1276-1279页

作者：马霖杰陈晓邹龙陈刚刘洪昆明医科大学附属甘美医院肝胆胰外科云南昆明650011

目的总结近年来干细胞治疗慢加急性肝衰竭(acute-on-chronic liver failure,ACLF)引发的相关基因变化及机理,以求指导ACLF临床治疗以及疗效评估。方法通过万方医学网、中国知网、Pubmed等检索数据库,检索出近年干细胞治疗ACLF引发的基... 详细信息

目的总结近年来干细胞治疗慢加急性肝衰竭(acute-on-chronic liver failure,ACLF)引发的相关基因变化及机理,以求指导ACLF临床治疗以及疗效评估。方法通过万方医学网、中国知网、Pubmed等检索数据库,检索出近年干细胞治疗ACLF引发的基因差异性表达,综合论述其治疗过程中引发的相关基因变化。结果国内外均有报道,干细胞治疗ACLF过程中引发mir27b、TRAIL、Tg737等基因改变,部分基因变化呈固定趋势。结论干细胞在治疗ACLF的过程中,引发mir27b、TRAIL、Tg737等基因变化,为下一步监测干细胞治疗ACLF疗效提供新的途径和方法。

关键词：干细胞慢加急性肝衰竭基因机理

减压阀植入术后减压阀暴露和脱出的原因分析及处理

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国际眼科杂志 2012年第2期12卷 346-347页

作者：盖春柳聂庆珠陈晓隆高殿文中国医科大学附属盛京医院眼科中国辽宁省沈阳市110004

目的:探讨青光眼减压阀植入术后减压阀暴露原因及处理。方法:对我院收治的8例青光眼减压阀植入术后减压阀暴露者,分析其暴露原因,并采用相应的处理方法。结果:减压阀暴露发生时间为术后6～31mo,经结膜修补或再次植入新阀后,随访6～24mo... 详细信息

目的:探讨青光眼减压阀植入术后减压阀暴露原因及处理。方法:对我院收治的8例青光眼减压阀植入术后减压阀暴露者,分析其暴露原因,并采用相应的处理方法。结果:减压阀暴露发生时间为术后6～31mo,经结膜修补或再次植入新阀后,随访6～24mo效果良好。结论:青光眼减压阀暴露的原因与手术技巧、患眼的病变等因素有关,所以术中应积极避免暴露因素。

关键词：青光眼减压阀暴露原因处理

The Security of Using Large Language Models:A Survey With Emphasis on ChatGPT

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IEEE/CAA Journal of Automatica Sinica 2025年第1期 1-26页

作者： Wei Zhou xiaogang Zhu Qing-long Han Lin Li xiao chen Sheng Wen Yang Xiang the School of Science Computing and Engineering Technologies Swinburne University of Technology IEEE the School of Computer and Mathematical Sciences the University of Adelaide Adelaide the Faculty of Science and Engineering Southern Cross University the School of Information and Physical Sciences the University of Newcastle

ChatGPT is a powerful artificial intelligence(AI)language model that has demonstrated significant improvements in various natural language processing(NLP) tasks. However, like any technology, it presents potential security risks that need to be carefully evaluated and addressed. In this survey, we provide an overview of the current state of research on security of using ChatGPT, with aspects of bias, disinformation, ethics, misuse,attacks and privacy. We review and discuss the literature on these topics and highlight open research questions and future *** this survey, we aim to contribute to the academic discourse on AI security, enriching the understanding of potential risks and mitigations. We anticipate that this survey will be valuable for various stakeholders involved in AI development and usage, including AI researchers, developers, policy makers, and end-users.

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自体结膜瓣移植治疗翼状胬肉的临床观察

国际眼科杂志 2012年第4期12卷 784-785页

作者：周雅丽底煜杨宏伟杨飏陈晓隆中国医科大学盛京医院眼科

目的:探讨一种治疗初发性翼状胬肉的新手术方法,寻求防止初发性翼状胬肉术后复发的最佳手术方法。方法:初发性翼状胬肉15例15眼,在手术显微镜下进行手术,彻底切除翼状胬肉组织,同时从上方取半圆形球结膜行自体球结膜移植。术后随访3～1... 详细信息

目的:探讨一种治疗初发性翼状胬肉的新手术方法,寻求防止初发性翼状胬肉术后复发的最佳手术方法。方法:初发性翼状胬肉15例15眼,在手术显微镜下进行手术,彻底切除翼状胬肉组织,同时从上方取半圆形球结膜行自体球结膜移植。术后随访3～12mo。结果:患者15例15眼均治愈,未见胬肉复发。术中术后未见并发症。结论:手术显微镜下行翼状胬肉切除联合自体球结膜移植手术,术后复发率低,是治疗初发性翼状胬肉的一种新的安全有效的方法。

关键词：翼状胬肉显微镜结膜瓣移植角膜缘干细胞