检索结果-南通市图书馆

Comparative Studies of Different Organs of Nyctanthes arbortristis in Modulation of Cytokines in Murine Model of Arthritis

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2007年第2期20卷 154-159页

作者： BRIJESH RATHORE BHOLANATH PAUL BHUSAN P CHAUDHURY ASHOK KUMAR SAXENA anand prakash sahu YOGENDRA KUMAR GUPTA Immunobiology Laboratory Central Pathology Laboratory Preventive Toxicology Laboratory Industrial Toxicology Research Centre M. G. MargLucknow 226001India

Objective To study the modulation effect of pro- and anti-inflammatory cytokines following long term use of water soluble ethanol extracts from different organs of Nyctanthes arbortristis （NAT） in mouse model of arthritis. Methods Arthritis was induced in mice by two injections of Freund＇s complete adjuvant on days 0 and 12 in the sub-planter surface of the right hind paw. Results Injection of adjuvant resulted in a maximum primary edema of the footpad with erythema, and edema and distortion of joints of the right hind paw after 24-48 hours. Second injection of FCA led to the formation of secondary swellings persisting more than four weeks that spread onto the other hind limb but to a lesser extent. Histological analysis of the ankle on day 47 showed marked evidence of cartilage destruction in association with pannus formation and moderate bone resorption. Proinfiammatory cytokine levels in the inflamed joint homogenate were elevated on days 2, 14, and 47. Oral administration of leaf and fruit extracts in arthritic mice reduced joint homogenate levels of tumor necrosis factor-α, interleukin-1β, and interleukin-6 on days 2, 14, and 47 in comparison to untreated arthritic mice. Intedeukin-10 level was elevated in the inflamed joint on days 2, 14, and 47 in comparisons to untreated arthritic mice. Confusion Evidence of lesser inflammation of the footpad and joint and associated histological observation support the therapeutic benefit of leaf and fruit extracts from Nyctanthes arbortristis. This study helps in understanding the mechanism of anti-inflammatory action of Nyctanthes arbortristis in the light of pro- and anti-inflammatory cytokine balance.

关键词： Nyctanthes arbortristis Arthritis TNF-α IL- 1β IL-6 IL-10

Nonmetric Traits in Permanent Teeth as Clues to Ethnicity in Vidarbha Subpopulation to Aid Forensic Profiling:Pilot Study

在线全文

学校读者我要写书评

暂无评论

Journal of Forensic Science and Medicine 2024年第1期10卷 11-19页

作者： Vaishali Amarlal Sadhwani Nilima prakash GLPradeep Rekha Patil Shubhechha anand Khivsara Sabiha Mokashi Khan MGV’S KBH Dental College NashikMaharashtraIndia Oral Cancer Screening and Awareness in Cancer Screening Vertical Indian Cancer SocietyMumbaiMaharashtraIndia

Introduction:Nonmetric dental traits have a crucial role in ethnic classification of populations that help in forensic racial *** studies have demonstrated the differences in the expression and frequency of dental traits between various ethnic groups for ancestry determination in the context of forensic dental *** present study is an attempt to assess the frequency and variation in nonmetric traits for establishing ethnicity in the Vidarbha ***:The aim of the study was to assess the frequency and variation of nonmetric traits in permanent teeth for establishing ethnicity in the Vidarbha *** and Methods:Participants of the Vidarbha subpopulation were selected by random sampling ***,premolars,and incisors were evaluated for frequency of nonmetric traits,and variations were graded according to Dentoanthropological System of State University of Arizona *** statistics,Chi-square test,and Student’s t-test were used for analysis of ***:The most common occlusal morphology in mandibular first and second molar was 5 cusp and 4 cusp,respectively,with the“+”groove *** 3 and cusp 4 were observed frequently in the maxillary *** lingual cusp was most commonly seen in mandibular premolars show while incisors showed faint ***:Our study concludes that nonmetric traits were present and showed variation in permanent maxillary and mandibular teeth among the Vidarbha *** 5 and Cusp 4 in first and second mandibular molars,respectively,groove pattern“+”and grade 1 protostylid were the most frequent grades observed in permanent mandibular *** lingual cusp was most commonly seen in mandibular premolars and faint shoveling was a notable feature in incisors of this population.

关键词： Cusp number ethnicity forensic anthropology molar protostylid

Higher Grain-Filling Rate in Inferior Spikelets of Tolerant Rice Genotype Offset Grain Yield Loss under Post-Anthesis High Night Temperatures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rice science 2024年第5期31卷 572-586,I0059-I0061页

作者： Nitin SHARMA Bhupinder SINGH Subbaiyan Gopala KRISHNAN Haritha BOLLINEDI Pranab Kumar MANDAL Milan Kumar LAL prakash Kumar JHA P.V.Vara PRASAD Anjali anand Division of Plant Physiology Indian Council of Agricultural Research(ICAR)-Indian Agricultural Research Institute(IARI)New Delhi 110012India Division of Environment Science ICAR-IARINew Delhi 110012India Division of Genetics ICAR-IARINew Delhi 110012India ICAR-National Institute for Plant Biotechnology New Delhi 110012India Division of Crop Physiology and Biochemistry ICAR-National Rice Research InstituteCuttack 753006India Department of Plant and Soil Sciences Mississippi State UniversityStarkvilleMS 39762USA Feed the Future Innovation Lab for Collaborative Research on Sustainable Intensification Kansas State UniversityManhattanKS 66506USA Department of Agronomy Kansas State UniversityManhattanKS 66506USA

Increased nighttime respiratory losses decrease the amount of photoassimilates available for plant growth and yield. We hypothesized that the increased respiratory carbon loss under high night temperatures(HNT) could be compensated for by increased photosynthesis during the day following HNT exposure. Two rice genotypes, Vandana(HNT-sensitive) and Nagina 22(HNT-tolerant), were exposed to HNT(4 ℃ above the control) from flowering to physiological maturity. They were assessed for alterations in the carbon balance of the source(flag leaf) and its subsequent impact on grain filling dynamics and the quality of spatially differentiated sinks(superior and inferior spikelets). Both genotypes exhibited significantly higher night respiration rates. However, only Nagina 22 compensated for the high respiration rates with an increased photosynthetic rate, resulting in a steady production of total dry matter under HNT. Nagina 22 also recorded a higher grain-filling rate, particularly at 5 and 10 d after flowering, with 1.5- and 4.0-fold increases in the translocation of ^(14)C sugars to the superior and inferior spikelets, respectively. The ratio of photosynthetic rate to respiratory rate on a leaf area basis was negatively correlated with spikelet sterility, resulting in a higher filled spikelet number and grain weight per plant, particularly for inferior grains in Nagina 22. Grain quality parameters such as head rice recovery, high-density grains, and gelatinization temperature were maintained in Nagina 22. An increase in the rheological properties of rice flour starch in Nagina 22 under HNT indicated the stability of starch and its ability to reorganize during the cooling process of product formation. Thus, our study showed that sink adjustments between superior and inferior spikelets favored the growth of inferior spikelets, which helped to offset the reduction in grain weight under HNT in the tolerant genotype Nagina 22.

关键词： high night temperature inferior grain pasting property radiolabeled sugar superior grain

Efficient ID-based proxy multi-signature scheme secure in random oracle

在线全文

学校读者我要写书评

暂无评论

Frontiers of Computer Science 2012年第4期6卷 421-428页

作者： Rajeev anand sahu Sahadeo PADHYE Department of Mathematics Motilal Nehru National Institute of TechnologyAllahabad-211004India

Proxy signature schemes enable an entity to del- egate its signing rights to any other party, called proxy signer. As a variant of proxy signature primitive, proxy multi- signature allows a group of original signers to delegate their signing capabilities to a single proxy signer in such a way that the proxy signer can sign a message on behalf of the group of original signers. We propose a concrete ID-based proxy multi-signature scheme from bilinear pairings. The proposed scheme is existential unforgeable against adaptively chosen message and given ID-attack in random oracle model under the computational Diltie-Hellman （CDH） assumption. The fascinating property of new scheme is that the size of a proxy multi-signature is independent of the number of original sign- ers. Furthermore the proposed scheme is simple and com- putationally more efficient than other ID-based proxy multi- signature schemes.

关键词： ID-based signature scheme bilinear pairings,proxy multi-signature computational Diffie-Hellman prob-lem (CDHP) random oracle

Effectiveness of m-health technology-enabled physical activity program on physical activity adoption and adherence in people with hypertension in India:A randomized controlled trial protocol

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chronic Diseases and Translational Medicine 2024年第2期10卷 92-101页

作者： Vidhi Thakar Sureshkumar Kamalakannan V.prakash Ashok&Rita Patel Institute of Physiotherapy Charotar University of Science and TechnologyChangaAnandGujaratIndia Department of Social Work Education and Community-WellbeingNorthumbria UniversityNewcastle upon TyneUK

Background Exercise and medication have similar benefits in reducing blood pressure(BP);however,hypertension management initiatives primarily focus on *** is due to scarce research on the effectiveness of implementation strategies for optimal exercise adoption and *** were found to be effective in delivering hypertension care and increase exercise *** this,only a small number of research projects in India have used smartphones as a strategy for managing *** We hypothesized that smartphone application-based care would lead to higher exercise adherence among adults(30–79 years)with hypertension compared to those who receive usual *** will be a multicentric,randomized controlled,parallel-design,superiority clinical *** outcome assessor and data analyst will be blinded to group *** in the intervention group will receive mobile application-based care for 6 *** in the usual care group will receive a standard *** groups will receive the same number of *** The primary outcome is the difference in the proportion of people adherent to the recommended level of physical activity evaluated using an exercise adherence rating scale in the intervention group and the control *** adoption will be measured as the percentage of eligible participants in each study setting willing to initiate the exercise *** secondary outcome includes differences in systolic and diastolic BP and self-management(evaluated using the Hypertension Self-Care Profile).The trial outcome will be accompanied by a process *** This research will inform about the comparative effectiveness of conventional and m-health interventions for exercise adoption and adherence in people with hypertension in resource-constrained settings.

关键词： hypertension low-and middle-income countries m-health physical activity adherence

Assessment of self-reacting bobbin tool friction stir welding for joining AZ31 magnesium alloy at inert gas environment

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2019年第4期7卷 661-671页

作者： prakash Kumar sahu Nikhil P Vasudevan Bipul Das Sukhomay Pal Department of Mechanical Engineering and IDM Joint Lab Tsinghua UniversityBeijing 100084China Larsen and Toubro Limited HaziraSuratGujarat 394510India Department of Mechanical Engineering National Institute of Technology Silchar788010 AssamIndia Department of Mechanical Engineering Indian Institute of Technology Guwahati781039 AssamIndia

Research work presented in this study has the primary target of exploring joint attributes of AZ31 magnesium alloys using friction stir welding process with a modified tool referred as bobbin *** of inert and open atmosphere on mechanical properties are evaluated over a wide range of welding speed and tool rotation *** of the research findings from the inert atmosphere bobbin tool were made with the traditional process of friction stir *** results depicted improved joint properties for inert atmosphere *** and intermediate range of tool rotational speed is found to be favorable for bobbin tool friction stir welding without and with an inert medium,*** atmosphere due to inert medium leads to less oxidation of the AZ31 Mg alloy leading to superior joint *** investigations are also made with the aim of evaluating the impact of bobbin tool and inert medium on joint *** each aspect for joining of AZ31 Mg alloy,bobbin tool with inert medium is found to be an effective solution for joining with improved mechanical properties compared to without inert bobbin tool as well as conventional tool friction stir welding.

关键词： Mg FSW Bobbin tool Process parameters Mechanical properties Fractography Microstructural characterization

Multi-response optimization of process parameters in friction stir welded AM20 magnesium alloy by Taguchi grey relational analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2015年第1期3卷 36-46页

作者： prakash Kumar sahu Sukhomay Pal Department of Mechanical Engineering Indian Institute of Technology Guwahati781039 AssamIndia

The purpose of this paper is to optimize the process parameter to get the better mechanical properties of friction stir welded AM20 magnesium alloy using Taguchi Grey relational analysis(GRA).The considered process parameters are welding speed,tool rotation speed,shoulder diameter and plunging *** experiments were carried out by using Taguchi's L18 factorial design of *** processes parameters were optimized and ranked the parameters based on the *** percentage influence of each process parameter on the weld quality was also quantified.A validation experimental run was conducted using optimal process condition,which was obtained from the analysis,to show the improvement in mechanical properties of the *** study also shows the feasibility of the GRA with Taguchi technique for improvement in welding quality of magnesium alloy.

关键词： Friction stir welding Magnesium alloy Tensile strength Bending strength Micro-hardness Optimization Taguchi Grey relational analysis

Hybrid fuzzy-grey-Taguchi based multi weld quality optimization of Al/Cu dissimilar friction stir welded joints

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Manufacturing 2016年第3期4卷 237-247页

作者： prakash Kumar sahu Kanchan Kumari Sukhomay Pal Surjya K. Pal Department of Mechanical Engineering Indian Institute of Technology Guwahati Guwahati Assam 781039 India Department of Mechanical Engineering Indian Institute of Technology Kharagpur Kharagpur West Bengal 721302India

Nowadays aluminum alloys substitute copper in various applications for weight reduction and cost savings. This paper presents fuzzy-grey Taguchi technique for optimization of friction stir welding condition with seven weld quality attributes of dissimilar A1/Cu joints with the minimum number of experiments for effective productivity and product quality. Taguchi＇s L16 orthogonal array was used to conduct the experiments. Fuzzy inference system was adapted to convert the multi quality characteristics into an equivalent single quality parameter which was opti- mized by Taguchi approach. Four parameters namely, rotational speed of the tool, welding speed, plunging depth and tool pin offset were varied in four levels for investi- gating the effects on the process output like tensile strength, compressive strength, percentage of elongation, bending angle, weld bead thickness and average hardness at the nugget zone. The hardness profile is consistent with the variation of the structure within the nugget zone （NZ）. Confirmation experiment was conducted using predicted optimum parameter setting and it showed that the proposed approach could efficiently optimize weld quality parame- ters. The microstructural analyses were also performed for all the zones of the joints at both Al and Cu sides. It revealed the finer grain size at the NZ compared to the base material due to dynamic recrystallization.

关键词： Dissimilar friction stir welding - Grey relational analysis. Fuzzy inference system Multi-response optimization Mechanical properties Microstructural analysis

Sarcopenia in Chronic Liver Disease:A Metabolic Perspective

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Translational Hepatology 2022年第6期10卷 1213-1222页

作者： Ramesh Kumar Sabbu Surya prakash Rajeev Nayan Priyadarshi Utpal anand Department of Gastroenterology All India Institute of Medical SciencesPatnaIndia Department of Radiodiagnosis All India Institute of Medical SciencesPatnaIndia Department of Surgical Gastroenterology All India Institute of Medical SciencesPatnaIndia

Sarcopenia,a condition of low muscle mass,quality,and strength,is commonly found in patients with chronic liver disease(CLD)and is associated with adverse clinical out-comes including reduction in quality of life,increased mor-tality,and complications.A major contributor to sarcopenia in CLD is the imbalance in muscle protein turnover wherein changes in various metabolic factors such as hyperammone-mia,amino acid deprivation,hormonal imbalance,gut dys-biosis,insulin resistance,chronic inflammation,*** important *** particular,hyperammonemia is a key mediator of the liver-gut axis and is known to contribute to sarcopenia by various mechanisms including increased ex-pression of myostatin,increased phosphorylation of eukary-otic initiation factor 2a,cataplerosis ofα-ketoglutarate,mi-tochondrial dysfunction,increased reactive oxygen species that decrease protein synthesis and increased autophagy-mediated *** muscle is a major organ of insulin-induced glucose metabolism,and sarcopenia is closely linked to insulin resistance and metabolic *** with liver cirrhosis are in a hypermetabolic state that is associated with catabolism and depletion of amino acids,particularly branched-chain amino *** can have significant implications for nonalcoholic fatty liver disease,the most common form of CLD worldwide,because of the close link between metabolic syndrome and *** review discusses the potential metabolic derange-ment as a cause or effect of sarcopenia in CLD,as well as interorgan crosstalk,which that might help identifying a novel therapeutic strategies.

关键词： Sarcopenia Liver cirrhosis Chronic liver disease Metabolism Hy-perammonemia