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Oxidative stability of green weakfish(Cynoscion virescens)by-product surimi and surimi gel enhanced with a Spondias mombin *** phenolic-rich extract during cold storage

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Food Bioscience 2022年第6期50卷 1260-1267页

作者： Thamyres César de Albuquerque Sousa Edson Luís Lima Silva Valquiria Cardoso da Silva Ferreira marta Suely Madruga Fábio Anderson pereira da Silva Postgraduate Program in Agrifood Technology Center for HumanSocial and Agrarian SciencesFederal University of ParaíbaBananeirasParaíba58220-000Brazil Center for Human Social and Agrarian SciencesFederal University of ParaíbaBananeirasParaíba58220-000Brazil Postgraduate Program in Food Science and Technology Technology CenterFederal University of ParaíbaJardim Cidade UniversitáriaJoão PessoaParaíba58900-000Brazil

The aim of this investigation was to assess the effect of yellow mombin bagasse extract(YMBE),alone or combined with commercial cryoprotectants,on the quality changes during cold storage of surimi and surimi gel prepared with the cutting by-product of green weakfish(Cynoscion virescens).Four treatments were elaborated:SC(surimi control),SE(surimi with addition of 1%extract),SCP(surimi with the addition of 4%sorbitol+4%sucrose)and SECP(surimi with addition of 1%extract+4%sorbitol+4%sucrose).The addition of the extract was effective in maintaining the whiteness of the surimi and its gel throughout *** the end of 12 days of cold storage,the surimi gel prepared with SE treatment presented high whiteness compared to the control *** inclusion of 1%YMBE in isolation or combined with commercial cryoprotectants showed a positive effect on the inhibition of lipid and protein oxidation of *** conclusion,YMBE extract is a promising alternative to be used as a natural food preservative in surimi and surimi gel.

关键词： Natural antioxidant Cryoprotectants Gelification Oxidation Surimi

The growth and production modeling of individual trees of Eucalyptus urophylla plantations

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Journal of Forestry Research 2020年第5期31卷 1663-1672页

作者： Joao Victor Nobre Carrijo ana Beatriz de Freitas Ferreira Marcela Costa Ferreira Mario Cesar de Aguiar Eder pereira Miguel Eraldo Aparecido Trondoli Matricardi Alba Valeria Rezende Department of Forestry Faculty of TechnologyUniversity of Brası´liaBrası´lia 70910-900Brazil

Individual tree models(ITMs)are classified as growth and production models for projecting current and future forest *** are more complex than other growth and production models,show a higher level of detail and,consequently,produce a better modeling ***,the accuracy and efficiency of ITMs have not been properly assessed to *** this study,we estimated the growth in height,diameter,and individual tree volume of a Eucalyptus urophylla plantation by applying an *** used a continuing forest inventory dataset in which 1554 individual trees within 29 permanent plots were measured in the field over a 6-year period(24 to 72 months).Each individual tree volume was estimated for future tree *** achieve this,we adjusted the model to predict the height and diameter growth,and the probability of mortality as a function of the competition *** ITM accuracy was assessed based on the analysis of variance results and,subsequently,the multiple mean comparison test at the 5%significance *** tree volumes predicted by the ITM for the forest stand aged 72 months,beginning at ages 24,36,48,and 60 months,were compared to the field measured tree volume acquired from the 72-month forest inventory that was used as the reference *** and observed tree volumes were similar when the estimation was based on the 48-month forest *** results might help to reduce financial costs of forest inventory because the ITM produces accurate future predictions of forest stand *** estimated ITM for Eucalyptus plantations using measurement intervals up to 2 years is recommended because it significantly reduced the projected volume discrepancy compared to the field measurements.

关键词： Competition index Forest production Forest site Simulation models Tree mortality

Washback of an Oral Assessment System in the EFL Classroom

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英语考试研究 2011年第5期 50-59页

作者： ana P. Munoz marta E. Alvarez

Current knowledge on esophageal atresia

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World Journal of Gastroenterology 2012年第28期18卷 3662-3672页

作者： Paulo Fernando Martins Pinheiro ana Cristina Simoes e Silva Regina Maria pereira Department of Pediatric Surgery Odilon Behrens HospitalAvenida JoséBonifácioSão CristovãoBelo Horizonte31210-690 Minas GeraisBrazil Department of Pediatrics Faculty of MedicineFederal University of Minas GeraisBelo Horizonte30130-100 Minas GeraisBrazil

Esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) is the most common congenital anomaly of the esophagus. The improvement of survival observed over the previous two decades is multifactorial and largely attributable to advances in neonatal intensive care, neonatal anesthesia, ventilatory and nutritional support, antibiotics, early surgical intervention, surgical materials and techniques. Indeed, mortality is currently limited to those cases with coexisting severe life-threatening anomalies. The diagnosis of EA is most commonly made during the first 24 h of life but may occur either antenatally or may be delayed. The primary surgical correction for EA and TEF is the best option in the absence of severe malformations. There is no ideal replacement for the esophagus and the optimal surgical treatment for patients with long-gap EA is still contro-versial. The primary complications during the postoperative period are leak and stenosis of the anastomosis, gastro-esophageal reflux, esophageal dysmotility, fistula recurrence, respiratory disorders and deformities of the thoracic wall. Data regarding long-term outcomes and follow-ups are limited for patients following EA/TEF repair. The determination of the risk factors for the complicated evolution following EA/TEF repair may positively impact long-term prognoses. Much remains to be studied regarding this condition. This manuscript provides a literature review of the current knowledge regarding EA.

关键词： Esophageal atresia Tracheoesophageal fistula Esophageal stenosis Long-gap Gastro-esophageal reflux

Risk Factors for Drug-Resistant Tuberculosis

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Journal of Tuberculosis Research 2014年第3期2卷 111-118页

作者： marta Gomes ana Correia Denisa Mendonca Raquel Duarte Occupational Health Centro Hospitalar Vila Nova de Gaia/Espinho EPEVila Nova de GaiaPortugal Public Health Department Northern Regional Health AdministrationPortoPortugal Institute of Public Health University of PortoPortoPortugal Institute of Biomedical Sciences Abel Salazar PortoPortugal Chest Disease Centre Vila Nova de Gaia Vila Nova de GaiaPortugal Pulmonology Centro Hospitalar de Vila Nova de Gaia/Espinho EPEVila Nova de GaiaPortugal Reference Centre for Multidrug Resistant Tuberculosis Northern Regional Health AdministrationPortoPortugal Department of Clinical Epidemiology Predictive Medicine and Public HealthUniversity of Porto Medical SchoolPortoPortugal

Objective: Drug resistance is considered one of the main threats for tuberculosis control. Our aim was to identify risk factors for drug resistance in tuberculosis patients in the Northern Portugal. Study Design and Methods: Retrospective case-control study. The medical records and drug susceptibility test data from TB patients diagnosed between 31 March 2009 and 1 April 2010 were examined. We enrolled 119 patients with any drug resistance to first line anti-TB drugs and 238 with drug-susceptible TB, matched by age group. Variables analyzed included: gender, country of origin, employment situation, site of disease, previous treatment, presence of diabetes mellitus, HIV infection, alcohol abuse, intravenous drug use, abuse of other drugs and smoking habits. Multivariate conditional logistic regression was used to identify independent predictors for drug-resistant TB. Results: Diabetes mellitus [adjusted odds ratio (OR): 3.54;95% CI: 1.45 - 8.66], intravenous drug use (OR: 4.77;95% CI: 1.24 - 18.32) and previous TB treatment (OR: 2.48;95% CI: 1.12 - 5.49) were found to be risk factors for drug-resistant disease development. Conclusions: Diabetes mellitus, prior tuberculosis treatment, and intravenous drug use were risk factors for drug-resistant disease. The association between diabetes and drug-resistant TB should be further explored. Identifying clinical predictors of drug resistance can allow prompt identification of patients at risk for drug-resistant TB.

关键词： Tuberculosis Drug-Resistance Risk Diabetes Portugal

Genetic dissection of climacteric fruit ripening in a melon population segregating for ripening behavior

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Horticulture Research 2020年第1期7卷 459-476页

作者： Lara pereira Miguel Santo Domingo Valentino Ruggieri Jason Argyris Michael A.Phillips Guangwei Zhao Qun Lian Yongyang Xu Yuhua He Sanwen Huang marta Pujol Jordi Garcia-Mas Centre for Research in Agricultural Genomics(CRAG)CSIC-IRTA-UAB-UB Edifici CRAGCampus UAB08193 CerdanyolaBarcelonaSpain IRTA(Institut de Recerca i Tecnologia Agroalimentàries) Edifici CRAGCampus UAB08193 CerdanyolaBarcelonaSpain Department of Biology University of Toronto–MississaugaMississaugaON L5L 1C6Canada Zhengzhou Fruit Research Institute Chinese Academy of Agricultural SciencesZhengzhouChina Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhenChina

Melon is as an alternative model to understand fruit ripening due to the coexistence of climacteric and non-climacteric varieties within the same species,allowing the study of the processes that regulate this complex trait with genetic *** phenotyped a population of recombinant inbred lines(RILs),obtained by crossing a climacteric(Védrantais,cantalupensis type)and a non-climcteric variety(Piel de Sapo T111,inodorus type),for traits related to climacteric maturation and ethylene *** in the RIL population exhibited various combinations of phenotypes that differed in the amount of ethylene produced,the early onset of ethylene production,and other phenotypes associated with *** characterized a major QTL on chromosome 8,ETHQV8.1,which is sufficient to activate climacteric ripening,and other minor QTLs that may modulate the climacteric *** ETHQV8.1 allele was validated by using two reciprocal introgression line populations generated by crossing Védrantais and Piel de Sapo and analyzing the ETHQV8.1 region in each of the genetic backgrounds.A Genome-wide association study(GWAS)using 211 accessions of the *** further identified two regions on chromosome 8 associated with the production of aromas,one of these regions overlapping with the 154.1 kb interval containing *** ETHQV8.1 region contains several candidate genes that may be related to fruit *** work sheds light into the regulation mechanisms of a complex trait such as fruit ripening.

关键词： behavior fruit reciprocal

Prognosis and follow-up of 135 patients with ischemic colitis over a five-year period

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World Journal of Gastroenterology 2013年第44期19卷 8042-8046页

作者： Angel Cosme Miguel Montoro Santos Santolaria ana B Sanchez-Puertolas marta Ponce Margarita Durán Jose Luis Cabriada Nerea Borda Cristina Sarasqueta Luis Bujanda Department of Gastroenterology Hospital de Donostia-Instituto BiodonostiaCentro de Investigaciones Biomédicas en Red en Enfermedades Hepáticas y Digestivas (CIBERehd) Universidad del País Vasco UPV/EHU 20014 San Sebastián Spain Department of Gastroenterology Hospital San Jorge22004 Huesca Spain Department of Gastroenterology Hospital Universitari La Fé 46026 Valencia Spain Department of Gastroenterology Hospital de Galdakao 48960 Bizcaia Spain Institute Biodonostia CIBEResp 20014 San Sebastián Spain

AIM:To study the prognosis(recurrence and mortality)of patients with ischemic colitis(IC).METHODS:This study was conducted in four Spanish hospitals,participants in the Ischemic Colitis in Spain study We analyzed prospectively 135 consecutive patients who met criteria for definitive or probable IC according to Brandt criteria,and follow up these patients during the next five years,***-term results(recurrence and mortality)were evaluated retrospectively after a median interval of 62 mo(range54-75 mo).RESULTS:Estimated IC recurrence rates were 2.9%,5.1%,8.1%and 9.7%at years 1,2,3 and 5 years,***-year survival was 69%(93 of 135)and 24%(10 of 42 patients)died for causes related to the *** these 10 patients,8 died in their first episode at hospital(4 had gangrenous colitis and 4 fulminant colitis)and 2 due to ***:The five-year recurrence rate of IC was *** the other hand,mortality during follow-up was high and was not associated with ischemic colitis.

关键词： Colonic Ischemic Recurrence Follow-up Mortality

Beta-blocker therapy in elderly patients with renal dysfunction and heart failure

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Journal of Geriatric Cardiology 2021年第1期18卷 20-29页

作者： Juan Martínez-Milla Marcelino Cortés García Julia Anna Palfy Mikel Taibo Urquía marta López Castillo ana Devesa Arbiol ana Lucía Rivero Monteagudo María Luisa Martín Mariscal Inés Jiménez-Varas Sem Briongos Figuero Juan Antonio Franco-Pelaéz JoséTuñón Department of Cardiology Hospital Universitario Fundación Jiménez Díaz-Quirónsalud Centro Nacional de Investigaciones Cardiovasculares MadridSpain Department of Cardiology Hospital Central de Asturias Department of Cardiology Hospital Universitario Ruber-Quirónsalud Department of Cardiology Hospital Universitario Infanta Leonor Department of Endocrinology Hospital Clínico San Carlos Universidad Autónoma de Madrid CIBERCV MadridSpain

OBJECTIVE To assess the role of beta-blockers(BB)in patients with chronic kidney disease(CKD)aged≥75 *** AND RESULTS From January 2008 to July 2014,we included 390 consecutive patients≥75 years of age with ejection fraction≤35%and glomerular filtration rate(GFR)≤60 m L/min per 1.73 m^*** analyzed the relationship between treatment with BB and mortality or cardiovascular *** mean age of our population was 82.6±4.1 *** ejection fraction was 27.9%±6.5%.GFR was 60-45 m L/min per 1.73 m^2 in 50.3%of patients,45-30 m L/min per 1.73 m^2 in 37.4%,and<30 m L/min per 1.73 m^2 in 12.3%.At the conclusion of follow-up,67.4%of patients were receiving *** median follow-up was28.04(IR:19.41-36.67)*** the study period,211 patients(54.1%)died and 257(65.9%)had a major cardiovascular event(death or hospitalization for heart failure).BB use was significantly associated with a reduced risk of death(HR=0.51,95%CI:0.35-0.74;P<0.001).Patients receiving BB consistently showed a reduced risk of death across the different stages of CKD:stage IIIa(GFR=30-45 m L/min per 1.73 m^2;HR=0.47,95%CI:0.26-0.86,P<0.0001),stage IIIb(GFR 30-45 m L/min per 1.73 m^2;HR=0.55,95%CI:0.26-1.06,P=0.007),and stages IV and V(GFR<30 m L/min per 1.73 m~2;HR=0.29,95%CI:0.11-0.76;P=0.047).CONCLUSIONS The use of BB in elderly patients with HFr EF and renal impairment was associated with a better *** of BB should be encouraged when possible.

关键词： CKD GFR Beta-blocker therapy in elderly patients with renal dysfunction and heart failure

Machine learning insights concerning inflammatory and liver-related risk comorbidities in non-communicable and viral diseases

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World Journal of Gastroenterology 2022年第44期28卷 6230-6248页

作者： J Alfredo Martínez marta Alonso-Bernáldez Diego Martínez-Urbistondo Juan A Vargas-Nuñez ana Ramírezde Molina Alberto Dávalos Omar Ramos-Lopez Precision Nutrition and Cardiometabolic Health Madrid Institute of Advanced Studies-Food InstituteMadrid 28049Spain Department of Internal Medicine Hospital Universitario HM SanchinarroMadrid 28050Spain Servicio de Medicina Interna Hospital Universitario Puerta de Hierro MajadahondaMadrid 28222MajadahondaSpain Molecular Oncology and Nutritional Genomics of Cancer Madrid Institute of Advanced Studies-Food InstituteMadrid 28049Spain Laboratory of Epigenetics of Lipid Metabolism Madrid Institute of Advanced Studies-Food InstituteMadrid 28049Spain Medicine and Psychology School Autonomous University of Baja CaliforniaTijuana 22390Baja CaliforniaMexico

The liver is a key organ involved in a wide range of functions,whose damage can lead to chronic liver disease(CLD).CLD accounts for more than two million deaths worldwide,becoming a social and economic burden for most *** the different factors that can cause CLD,alcohol abuse,viruses,drug treatments,and unhealthy dietary patterns top the *** conditions prompt and perpetuate an inflammatory environment and oxidative stress imbalance that favor the development of hepatic *** stages of fibrosis can eventually lead to cirrhosis or hepatocellular carcinoma(HCC).Despite the advances achieved in this field,new approaches are needed for the prevention,diagnosis,treatment,and prognosis of *** this context,the scientific community is using machine learning(ML)algorithms to integrate and process vast amounts of data with unprecedented *** techniques allow the integration of anthropometric,genetic,clinical,biochemical,dietary,lifestyle and omics data,giving new insights to tackle CLD and bringing personalized medicine a step *** review summarizes the investigations where ML techniques have been applied to study new approaches that could be used in inflammatoryrelated,hepatitis viruses-induced,and coronavirus disease 2019-induced liver damage and enlighten the factors involved in CLD development.

关键词： Machine learning Liver inflammation Liver disease Viral diseases Comorbidity