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Vibration analysis and Fatigue Assessment of *** I:Human Rhythmic Activities

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Journal of Civil Engineering and Architecture 2021年第10期15卷 497-503页

作者： ana C.S.da Silva Elisângela A.R.Santos Leandro A.Deus Mayara M.Martins JoséG.S.da Silva State University of Rio de Janeiro(UERJ) Rio de Janeiro/RJ 20550-900Brazil Structural Engineering Department(ESTR) State University of Rio de Janeiro(UERJ)Rio de Janeiro/RJ 20550-900Brazil

Structural problems associated with excessive vibration of building floor systems when subjected to human rhythmic activities have been *** this context,this research work aims to develop an analysis methodology to evaluate the human comfort and assess the fatigue performance of steel-concrete composite floors when subjected to human rhythmic activities(aerobics).The investigated structural model corresponds to a steel-concrete floor with dimensions of 10 m×10 m and a total area of 100 m^(2).The numerical model developed for the dynamic analysis of the floor adopted the usual mesh refinement techniques present in finite element method(FEM)simulations implemented in the ANSYS *** investigated floor dynamic response was calculated through the consideration of people practicing rhythmic activities on the structure,in order to verify the occurrence of excessive vibration and to assess the human *** fatigue assessment is based on a linear cumulative damage rule through the use of the Rainflow-counting algorithm and S-N curves from traditional design *** results indicated that,in several analysed situations,the investigated floor presents excessive vibration and user’s *** the other hand,the structure service life values were higher than those proposed by the design codes,ensuring that the members,connections and joints will not fail by fatigue cracking.

关键词： Steel-concrete composite floors human rhythmic activities vibration analysis human comfort fatigue assessment.

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*** TZ8耐乙醇菌株的筛选及发酵性能研究

生物学杂志 2009年第1期26卷 27-30页

作者：周逢云汤斌张庆庆翟光雯陈阿娜安徽工程科技学院生化工程系微生物发酵安徽省工程技术研究中心芜湖241000

以***8为出发菌株,利用1%溶壁酶和1%蜗牛酶酶解1.5h,制备成***8原生质体,并对原生质体进行紫外诱变,以含不同浓度乙醇的木糖液体培养基培养进行初筛和复筛,获得一株遗传性能稳定、耐乙醇能力达5.5%(v/v)的菌株***8-4,比初始菌株耐乙醇... 详细信息

以***8为出发菌株,利用1%溶壁酶和1%蜗牛酶酶解1.5h,制备成***8原生质体,并对原生质体进行紫外诱变,以含不同浓度乙醇的木糖液体培养基培养进行初筛和复筛,获得一株遗传性能稳定、耐乙醇能力达5.5%(v/v)的菌株***8-4,比初始菌株耐乙醇能力提高了2%。对突变株***8-4发酵性能的研究结果表明:***8-4发酵糖能力从80g/L(葡糖糖和木糖比为2∶1)提高到120g/L,最大乙醇产量从27.41g/L提高到43.12g/L。

关键词：原生质体诱变休哈塔假丝酵母乙醇发酵

Accuracy of gestalt perception of acute chest pain in predicting coronary artery disease

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World Journal of Cardiology 2017年第3期9卷 241-247页

作者： Cláudio Marcelo Bittencourt das Virgens Laudenor Lemos Jr Márcia Noya-Rabelo Manuela Campelo Carvalhal Antonio Maurício dos Santos Cerqueira Junior Fernanda Oliveira de Andrade Lopes Nicole Cruz de Sá Jéssica Gonzalez Suerdieck Thiago Menezes Barbosa de Souza Vitor Calixto de Almeida Correia Gabriella Sant’ana Sodré AndréBarcelos da Silva Felipe Kalil Beirao Alexandre Felipe Rodrigues Marques Ferreira Luís Cláudio Lemos Correia Department of Cardiology Hospital Sao Rafael Department of Cardiology Hospital Português Bahiana School of Medicine and Public Health

AIM To test accuracy and reproducibility of gestalt to predict obstructive coronary artery disease(CAD)in patients with acute chest *** We studied individuals who were consecutively admitted to our Chest Pain *** admission,investigators performed a standardized interview and recorded14 chest pain *** on these features,a cardiologist who was blind to other clinical characteristics made unstructured judgment of CAD probability,both numerically and *** the reference standard for testing the accuracy of gestalt,angiography was required to rule-in CAD,while either angiography or non-invasive test could be used to *** order to assess reproducibility,a second cardiologist did the same *** In a sample of 330 patients,the prevalence of obstructive CAD was 48%.Gestalt’s numerical probability was associated with CAD,but the area under the curve of0.61(95%CI:0.55-0.67)indicated low level of ***,categorical definition of typical chest pain had a sensitivity of 48%(95%CI:40%-55%)and specificity of 66%(95%CI:59%-73%),yielding a negligible positive likelihood ratio of 1.4(95%CI:0.65-2.0)and negative likelihood ratio of 0.79(95%CI:0.62-1.02).Agreement between the two cardiologists was poor in the numerical classification(95%limits of agreement=-71%to 51%)and categorical definition of typical pain(Kappa=0.29;95%CI:0.21-0.37).CONCLUSION Clinical judgment based on a combination of chest pain features is neither accurate nor reproducible in predicting obstructive CAD in the acute setting.

关键词： Acute chest pain Clinical judgment Gestalt Coronary artery disease Acute coronary syndrome

树商陆:潮湿的潘帕斯大草原景观的实践与表达

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风景园林 2019年第2期26卷 53-62页

作者：安纳·瓦拉里诺·卡赞斯坦() 梁艺馨(译) 钱丽源(校) 乌拉圭共和国大学建筑设计和城市规划学院北京林业大学园林学院北京100083 西南交通大学建筑与设计学院风景园林系成都611756 西班牙加泰罗尼亚理工大学

学名为Phytolacca dioica的树种将会贯穿全文。此树种在乌拉圭的通用名叫做树商陆,是本研究缘起的核心。它是潘帕斯大草原的标志性物种,也是乌拉圭景观特质的基础。树商陆在研究和教育工作领域的目标和意义在于将艺术、人类、社会和自... 详细信息

学名为Phytolacca dioica的树种将会贯穿全文。此树种在乌拉圭的通用名叫做树商陆,是本研究缘起的核心。它是潘帕斯大草原的标志性物种,也是乌拉圭景观特质的基础。树商陆在研究和教育工作领域的目标和意义在于将艺术、人类、社会和自然科学联系起来。对树商陆在潘帕斯大草原湿润气候下所表现出的景观价值进行研究。提高了公众对自然元素同景观价值、地方故事间关系的认知度和敏感度。这加强了对遗产以及领土和文化融合的集体责任感。理论往往需要适用于方法论,并协作实践性的工作。例如现场活动与ICT(门户网站http://***)的相互关联,这便如不断往返于科学文化的普及与流行文化的智慧,用跨学科的方式建构知识。

关键词：乌拉圭树商陆人居环境和自然风景园林 ICT 和协作制图

Drug-induced liver injury and COVID-19:Use of artificial intelligence and the updated Roussel Uclaf Causality Assessment Method in clinical practice

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Artificial Intelligence in Gastroenterology 2023年第2期4卷 36-47页

作者： Gabriela Xavier Ortiz ana Helena Dias Pereira dos Santos Ulbrich Gabriele Lenhart Henrique Dias Pereirados Santos Karin Hepp Schwambach Matheus William Becker Carine Raquel Blatt Graduate Program in Medicine–Hepatology Federal University of Health Sciences of Porto AlegrePorto Alegre 90050-170Brazil Institute of Artificial Intelligence in Healthcare Porto Alegre 90.620-200Brazil Multiprofessional Residency Integrated in Health Federal University of Health Sciences of Porto AlegrePorto Alegre 90050-170Brazil Department of Pharmacoscience Graduate Program in Medicine–HepatologyFederal University of Health Sciences of Porto AlegrePorto Alegre 90050-170Brazil

BACKGROUND Liver injury is a relevant condition in coronavirus disease 2019(COVID-19)*** varies from direct infection by virus,systemic inflammation or drug-induced adverse reaction(DILI).DILI detection and monitoring is clinically relevant,as it may contribute to poor prognosis,prolonged hospitalization and increase indirect healthcare *** Intelligence(AI)applied in data mining of electronic medical records combining abnormal liver tests,keyword searching tools,and risk factors analysis is a relevant opportunity for early DILI detection by automated *** To describe DILI cases in COVID-19 inpatients detected from data mining in electronic medical records(EMR)using AI and the updated Roussel Uclaf Causality Assessment Method(RUCAM).METHODS The study was conducted in March 2021 in a hospital in southern *** NoHarm©system uses AI to support decision making in clinical *** admissions were 100523 during this period,of which 478 met the inclusion *** these,290 inpatients were excluded due to alternative causes of liver injury and/or due to not having *** manually reviewed the EMR of 188 patients for DILI *** of clinical information excluded most eligible *** DILI assessment causality was possible via the updated RUCAM in 17 *** Mean patient age was 53 years(SD±18.37;range 22-83),most were male(70%),and admitted to the non-intensive care unit sector(65%).Liver injury pattern was mainly mixed,mean time to normalization of liver markers was 10 d,and mean length of hospitalization was 20.5 d(SD±16;range 7-70).Almost all patients recovered from DILI and one patient died of multiple organ *** were 31 suspected drugs with the following RUCAM score:Possible(n=24),probable(n=5),and unlikely(n=2).DILI agents in our study were ivermectin,bicalutamide,linezolid,azithromycin,ceftriaxone,amoxicillin-clavulanate,tocilizumab,piperacillin-tazobactam,and a

关键词： Chemical and drug induced liver injury RUCAM Artificial intelligence COVID-19 Liver injury

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牛奶和钙盐在胃肠道内的钙吸收

中国临床营养杂志 2003年第1期11卷 75-75页

作者： Sheikh MS Santa ana Nicar MJ Schiller LR Fordtran JS 周建烈 Baylor University Medical Center

目的探讨谷氨酰胺对肝脏移植后应激蛋白表达的影响.方法 A组10例为正常肝脏;B组10例肝脏移植后不用丙氨酰谷氨酰胺二肽(Ala-Gln);C组8例肝脏移植后用Ala-Gln.观察标本的病理学改变和患者的营养状况,用免疫组织化学及原位杂交方法检测HS... 详细信息

目的探讨谷氨酰胺对肝脏移植后应激蛋白表达的影响.方法 A组10例为正常肝脏;B组10例肝脏移植后不用丙氨酰谷氨酰胺二肽(Ala-Gln);C组8例肝脏移植后用Ala-Gln.观察标本的病理学改变和患者的营养状况,用免疫组织化学及原位杂交方法检测HSP70、HO-1蛋白和mRNA表达水平.结果 B组和C组均未见免疫排斥反应,营养状况尚可;HSP70、HO-1蛋白及mRNA表达水平移植肝脏均升高,且应用Ala-Gln后更高.结论谷氨酰胺能增加供肝细胞应激蛋白基因转录和表达,加强肝细胞自我保护作用.

关键词：牛奶钙盐胃肠道内钙吸收

紫外探伤技术在变电设备电晕放电检测中的应用

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电工技术 2018年第7期 70-71,80页

作者：郑云海王门鸿吴奇宝高阿娜马会军泉州供电公司福建泉州362000

介绍紫外探伤技术的主要工作原理及检测案例,阐述现场检测积累的经验,提出对检测结果运用多种检测手段的综合评价,准确判断被检测设备的状态。

关键词：电晕放电紫外探伤变电设备

Production of Volatile Moth Sex Pheromones in Transgenic Nicotiana benthamiana Plants

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BioDesign Research 2021年第1期2021卷 79-95页

作者： Rubén Mateos-Fernández Elena Moreno-Giménez Silvia Gianoglio Alfredo Quijano-Rubio Jose Gavaldá-García Lucía Estellés Alba Rubert JoséLuis Rambla Marta Vazquez-Vilar Estefanía Huet Asunción Fernández-del-Carmen ana Espinosa-Ruiz Mojca Juteršek Sandra Vacas Ismael Navarro Vicente Navarro-Llopis Jaime Primo Diego Orzáez Institute for Plant Molecular and Cell Biology(IBMCP) Consejo Superior de Investigaciones Científicas(CSIC)-Universidad Politécnica de Valencia(UPV)ValenciaSpain Jaume I University Castellon de la PlanaSpain Department of Biotechnology and Systems Biology National Institute of BiologyLjubljanaSlovenia Jožef Stefan International Postgraduate School LjubljanaSlovenia Centro de Ecología Química Agrícola Instituto Agroforestal del MediterráneoUniversitat Politècnica de ValènciaValenciaSpain Ecología Y Protección Agrícola SL ValenciaSpain

Plant-based bioproduction of insect sex pheromones has been proposed as an innovative strategy to increase the sustainability of pest control in ***,we describe the engineering of transgenic plants producing(Z)-11-hexadecenol(Z11-16OH)and(Z)-11-hexadecenyl acetate(Z11-16OAc),two main volatile components in many Lepidoptera sex pheromone *** assembled multigene DNA constructs encoding the pheromone biosynthetic pathway and stably transformed them into Nicotiana benthamiana *** constructs contained the Amyelois transitella AtrΔ11 desaturase gene,the Helicoverpa armigera fatty acyl reductase HarFAR gene,and the Euonymus alatus diacylglycerol acetyltransferase EaDAct gene in different *** the pheromone-producing plants showed dwarf phenotypes,the severity of which correlated with pheromone *** but one of the recovered lines produced high levels of Z11-16OH,but very low levels of Z11-16OAc,probably as a result of recurrent truncations at the level of the EaDAct *** one plant line(SxPv1.2)was recovered that harboured an intact pheromone pathway and which produced moderate levels of Z11-16OAc(11.8μg g^(-1) FW)and high levels of Z11-16OH(111.4μg g^(-1)).Z11-16OAc production was accompanied in SxPv1.2 by a partial recovery of the dwarf ***1.2 was used to estimate the rates of volatile pheromone release,which resulted in 8.48 ng g-1 FW per day for Z11-16OH and 9.44 ng g^(-1 )FW per day for *** results suggest that pheromone release acts as a limiting factor in pheromone biodispenser strategies and establish a roadmap for biotechnological improvements.

关键词： release dwarf transformed

Vibration analysis and Fatigue Assessment of *** II:Mechanical Equipment

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Journal of Civil Engineering and Architecture 2021年第10期15卷 504-510页

作者： ana C.S.da Silva Gabriel M.Sant’Anna Lucia H.G.Cardoso AndréV.Castilho JoséG.S.da Silva State University of Rio de Janeiro(UERJ) Rio de Janeiro/RJ 20550-900Brazil Structural Engineering Department(ESTR) State University of Rio de Janeiro(UERJ)Rio de Janeiro/RJ 20550-900Brazil

Floors subjected to mechanical equipment loads frequently present problems associated with excessive vibration which can cause human discomfort or even reduce the structure service *** this context,this work aims to develop an analysis methodology in order to assess the fatigue performance of steel-concrete composite floors,when subjected to vibrations induced by mechanical *** studied structural model corresponds to a steel-concrete composite floor spanning 10 m by 10 m,with a total area of 100 m^(2).The numerical model developed for the dynamic analysis adopted the usual mesh refinement techniques present in finite element method(FEM)simulations implemented in the ANSYS *** investigated floor dynamic response was calculated through the consideration of the dynamic loadings imposed by the mechanical equipment,simulated based on the use of harmonic forces applied on the concrete ***,the dynamic structural response was performed considering several scenarios for the positioning of the equipment,in order to verify the occurrence of excessive *** fatigue assessment is based on a linear cumulative damage rule through the use of the Rainflow-counting algorithm and S-N curves from traditional design *** results of this investigation indicated that the equipment position affects directly the floor dynamic structural response and also significantly influences the structure service life.

关键词： Steel-concrete composite floors mechanical equipment dynamic structural analysis fatigue assessment.