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Conocarpus erectus L., a plant with a high content of structural sugars, ions and phenolic compounds, shows antioxidant and antimicrobial properties promoted by different organic fractions

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Asian Pacific Journal of Tropical Biomedicine 2018年第9期8卷 463-470页

作者： Dayane Kelly Dias do Nascimento Santos Weslley Henrique de Oliveira Melo anastassia Mariáh Nunes de Oliveira Lima Iranildo Joseda Cruz Filho Glaucia Manoella de Souza Lima Tulio Diego da Silva Maiara Celine de Moura Marcia Silva do Nascimento ana maria souto maior Thiago Henrique Napoleao Cristiane Moutinho Lagos de Melo Department of Biochemistry Biosciences Centre Federal University of Pernambuco Department of Antibiotics Biosciences Centre Federal University of Pernambuco Center of Strategic Technologies of the Northeast

Objective: To evaluate the structural and chemical composition of plant and the antioxidant and antimicrobial activities promoted by hexanic, ethanolic and ethyl acetate fractions obtained from leaves of Conocarpus ***: Organic fractions were characterized through UPLC-MS and *** potential was performed through DPPH and molybdenum phosphate *** and antifungal assays were performed in accordance with Clinical and Laboratory Standards Institute ***: The obtained biomass of Conocarpus erectus leaves showed the high presence of glucose(0.45 g/L), cellulose(28.69%), Na(55.126 μg/L) and K(31.163 μg/L).We identified seven compounds in the hexanic and ethyl acetate fractions, and eight compounds in ethanolic ***, phenolic compounds are prevalent in all organic fractions with values of(10.04 ± 0.24),(221.26 ± 1.84),(340.53 ± 0.84) mg/g GAE to hexanic, ethyl acetate and ethanolic fraction, *** results showed a high potential in ethyl acetate fraction(71.82 ± 6.87)% and(10.89 ± 0.05)% in DPPH and molybdenum phosphate techniques, *** ethanolic fraction showed moderate bacteriostatic and bactericidal activity against Staphylococcus aureus and presented a high fungistatic potential for all Candida species ***: Organic fractions obtained from leaves of Conocarpus erectus present antimicrobial and antioxidant properties, and these findings contribute to scientific information for the effectiveness on use of this plant in the development of a phytotherapic compound.

关键词： Combretaceae Phenolic compounds Antimicrobial activity Antioxidant

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Phytochemical bioprospecting, antioxidant, antimicrobial and cytotoxicity activities of saline extract from Tithonia diversifolia(Hemsl) *** leaves

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Asian Pacific Journal of Tropical Biomedicine 2018年第5期8卷 245-253页

作者： Bruno Rafael Barboza Bárbara Rafaela da Silva Barros Bárbara de Azevedo Ramos Maiara Celine de Moura Thiago Henrique Napoleao maria Tereza dos Santos Correia Luana Cassandra Breitenbach Barroso Coelho Iranildo José da Cruz Filho ana maria souto maior Túlio Diego da Silva Leylianne de Cássia Rodrigues Nerys Edson Renan Barros de Santana Cláudia Sampaio de Andrade Lima Virgínia maria Barros de Lorena Cristiane Moutinho Lagos de Melo Department of Antibiotics Biosciences Centre Federal University of Pernambuco Department of Biochemistry Biosciences Centre Federal University of Pernambuco Center for Strategic Techmologies of the Northeast Department of Biophysics Biosciences Centre Federal University of Pernambuco Aggeu Magalhaes Institute IAM/FIOCRUZ

Objective:To evaluate antimicrobial and antioxidant properties of saline extract from Tithonia diversifolia leaves by phytochemical bioprospecting,and investigate its safety against animal ***:The saline extract was prepared,with NaCl(0.15 M),by constant stirring of the dried and pulverized leaves,followed by volume reduction by *** extract was phytochemical characterized using ultra-performance liquid chromatography,and total phenol and flavonoid analysis also was *** antioxidant capacity was determined through DPPH*radical,the antimicrobial property was evaluated against standard bacteria and fungi,and the viability assays were performed against mice ***:Fifteen compounds were identified belonging to two main classes terpenoids and *** extract showed 22.185 mg GAE/g of total phenolic compounds and 3.220 mg QE/g of ***,extract showed higher antioxidant ability similar to butylated hydroxytoluene a standard molecule[(3.042±0.019)mg AAE/g and(4.12±0.10)mg AAE/g to saline extract and butylated hydroxytoluene,respectively].The antimicrobial assays demonstrated that the extract had a significant antifungal potential against Candida species and could be used with safety against mice splenocytes,in concentrations lower than 50μg/mL,promoting higher proliferation in these ***:Saline extract from Tithonia diversifolia leaves presents potential antioxidant,antifungal properties and induces immunostimulation in mice splenocytes.

关键词： Tithonia diversifolia Extract Antioxidant Antifungal properties Immunostimulation

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Dynamic Balance in Children With Trisomy 21:A Pilot Study

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Psychology Research 2020年第7期10卷 285-288页

作者： David Catela ana Paula Seabra Bernardo Matias Miguel Nunes Pedro Neves Samuel Rodrigues Higher School of Sports Sciences of Rio maior Polytechnique Institute of SantarémSantarémPortugal Life Quality Research Centre(CIEQV) Rio MaiorPortugal Research Unity of the Polytechnique Institute of Santarém SantarémPortugal

At age 5,children with trisomy 21 have roughly 2 years of delayed motor *** aimed to verify if children with trisomy 21(AD)(N=6,7.67±1.51 years)had a similar performance to children with a typical development(TD)(N=37,5.19±0.40 years old),in a playful motor action(to spin on herself until she cannot get more).On average,ADs gave less laps,for less time,spending more time per rotation,but without significant *** the AD,one-third fell and rose to continue to spin;one-third stopped and resumed spinning(with intervals of 2.05±0.86s).Three ADs performed the action counterclockwise and the other three in clockwise *** results support the hypothesis that AD can perform the activity of spinning,with DT(significantly)younger,allowing to AD momentary pauses and conditions for their physical security.

关键词： children dynamic balance motor development trisomy 21

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Short Report:Babywalkers Use and Age of Autonomous Sitting and Walking in Portuguese Infants

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Psychology Research 2020年第7期10卷 289-292页

作者： David Catela Carolina Lagoiro Carolina Gonçalves Filipa Passadinhas Isabela Ribeiro ana Paula Seabra Higher School of Sports Sciences of Rio maior Polytechnique Institute of SantarémSantarémPortugal Life Quality Research Centre(CIEQV) Rio MaiorPortugal Research Unity of the Polytechnique Institute of Santarém SantarémPortugal Higher School of Education of Santarém Polytechnique Institute of SantarémSantarémPortugal

Babywalkers are wheeled seats for infants that support their weight and allow them to move around,pushing the floor with their feet or feet’s *** purpose of the present study was to verify if Portuguese infants that used babywalker gained or not temporal advantage compared to infants who did not use any instrument for learning to *** were obtained through a structured questionnaire for parents,with closed *** revealed that babywalkers use does not afford advantages in the acquisition of independent *** absence of association between seat and walk autonomously in babywalker users that also used other walk-helper(e.g.,harness belt)reinforces the hypothesis that the use of these equipments may disrupt normal process of transition between seat and walk in *** the sample of the present study,a great percentage of Portuguese parents still presume that the use of babywalkers or similar equipments are necessary for independent walking *** should be discouraged as an instrument for independent walk learning,and be replaced by functional stimulation,like stepping reflex systematic practice.

关键词： infants babywalker autonomous seat autonomous walk

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