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Impaired swallowing mechanics of post radiation therapy head and neck cancer patients: A retrospective videofluoroscopic study

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World Journal of Radiology 2016年第2期8卷 192-199页

作者： William G Pearson Jr Alisa A Davidoff Zachary m Smith Dorothy E Adams Susan E Langmore Department of Cellular Biology and ana-tomy Medical College of Georgia at Georgia Regents University Department of Otolaryngology Medical College of Georgia at Georgia Regents University Sargent College Boston University Department of Otolaryngology Head and Neck Surgery Boston University School of Medicine

AIm: To determine swallowing outcomes and hyolaryngeal mechanics associated with post radiation therapy head and neck cancer(rt HNC) patients using videofluoroscopic swallow studies. mETHODS: In this retrospective cohort study, video-fluoroscopic images of rt HNC patients(n = 21) were compared with age and gender matched controls(n = 21). Penetration-aspiration of the bolus and bolus residue were measured as swallowing outcome variables. Timing and displacement measurements of the anterior and posterior muscular slings elevating the hyolaryngeal complex were acquired. Coordinate data of anatomical landmarks mapping the action of the anterior muscles(suprahyoid muscles) and posterior muscles(long pharyngeal muscles) were used to calculate the distance measurements, and slice numbers were used to calculate time intervals. Canonical variate analysis with post-hoc discriminant function analysis was performed on coordinate data to determine multivariate mechanics of swallowing associated with treatment. Pharyngeal constriction ratio(PCR) was also measured to determine if weak pharyngeal constriction is associated with post radiation ***: The rt HNC group was characterized by poor swallowing outcomes compared to the control group in regards to: Penetration-aspiration scale(P malized residue ratio scale(NRRS) for the valleculae(P = 0.002) and NRRS for the piriform sinuses(P = 0.003). Timing and distance measurements of the anterior muscular sling were not significantly different in the two groups, whereas for the PmS time of displacement was abbreviated(P = 0.002) and distance of excursion was reduced(P = 0.02) in the rt HNC group. A canonical variate analysis shows a significant reduction in pharyngeal mechanics in the rt HNC group(P < 0.0001). The PCR was significantly higher in the test group than the control group(P = 0.0001) indicating reduced efficiency in pharyngeal clearance. CONCLUSION: Using videofluoroscopy, this study shows rt HNC pati

关键词： Swallow mechanics Post radiation Head and neck cancer Fluoroscopy anatomy

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mAGmA艺术与会议中心西班牙特内里费岛

世界建筑导报 2022年第1期37卷 25-27页

作者：费尔南多·梅尼斯菲利佩·阿尔滕戈·鲁菲诺何塞·玛丽亚·尔盖兹帕斯特拉纳安德烈亚斯·韦纳赫特埃丝特·塞巴洛斯安娜·萨利纳斯不详

该建筑位于半干旱地区又有如此高度,使得其轮廓与大海相映成趣,由于其引人注目的形状、粗糙质感和石质颜色,在视觉上与景观紧密融合在一起。从地面冒出来的十三块“岩石”有着液体流线般的屋顶轮廓,各自提供不同的服务。这种起伏的表面... 详细信息

该建筑位于半干旱地区又有如此高度,使得其轮廓与大海相映成趣,由于其引人注目的形状、粗糙质感和石质颜色,在视觉上与景观紧密融合在一起。从地面冒出来的十三块“岩石”有着液体流线般的屋顶轮廓,各自提供不同的服务。这种起伏的表面只是为了留出空隙,以便自然通风和采光。在内部,经大量研究和现场调整,空间形状可满足具体的声学需求。音乐厅和国会大厅占地2354平方米,最多可容纳2500人,也可以分为9个小房间,每个房间可容纳300人。会议室占地1865平方米,可划分为更小的空间,每个小空间可容纳200至250人。这些改造可通过移动墙壁来进行,这些墙壁内置有隔音材料,不用时可存放其起来。为了确保建筑物与周围环境的融合,混凝土混合物中还添加了一种名为chasnera的当地石头,屋顶则使用了由植物纤维制成的面板,用了一种与景观相似的颜色。建筑师与艺术家合作进行室内设计:兰萨罗特的画家和雕塑家胡安·戈帕尔(Juan Gopar)设计了自助餐厅的天花板灯,由可回收塑料袋制成;特内里费戏剧艺术总监卡洛斯·贝尔达(Carlos Belda)设计了灯光;特内里费艺术家米里亚姆·杜兰戈(miriam Durango)设计了标识牌;加拿大裔美国工业设计师卡里姆·拉希德(Karim Rashid)签名的家具在原本朴素的氛围中显得色彩斑斓。

关键词：隔音材料室内设计自然通风空间形状现场调整标识牌杜兰戈拉希德

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老海勒鲁普高中体育馆

城市环境设计 2019年第2期118卷 114-127页

作者： ana merino Anders Hjortn?s Christian Alvarez Dennis Rasmussen Gül Ertekin Henrick Poulsen Hjalti Gestsson Jan magasanik Jakob Lange Jacob Thomsen Jeppe Ecklon Ji-young Yoon michael Sch?nemann Narisara Schr?der Riccardo mariano Rune Hansen Snorre Nash Thomas Juul-Jensen Vincent He Xu Li Agnete Jukneviciute Ambra Chiesa Brigitta Gulyás Dennis Rasmussen Enea michelesio Greta Krenciute H?gni Laksáfoss Isabella Eriksson Jan magasanik mikkel marcker Stubgaard Jeppe Ecklon Kamilla Heskje michael Sch?nemann Narisara Schr?der Thomas Juul-Jensen Brigitta Gulyás Enea michelesio Jakob Lange mikkel marcker Stubgaard Narisara Schr?der Tobias Hjortdal Iwan Baan Peter moldow Rasmus Hjortshoj Jens Lindhe 朱翰林

位于哥本哈根北部的老海勒鲁普高中,内部拥有1100m2的多功能大厅和最新的两层建筑,为现有学生提供了广阔的社交和创意展示空间,同时提升学校的容量,以应对持续增长的人口需求。原本校园旁边的一栋建筑里,体育设施匮乏而无法满足需求;老... 详细信息

位于哥本哈根北部的老海勒鲁普高中,内部拥有1100m2的多功能大厅和最新的两层建筑,为现有学生提供了广阔的社交和创意展示空间,同时提升学校的容量,以应对持续增长的人口需求。原本校园旁边的一栋建筑里,体育设施匮乏而无法满足需求;老海勒鲁普高中也缺少大型多功能空间,用以举办体育活动、毕业典礼和社交聚会。为此,BIG为学生

关键词：体育馆

离子束反应溅射沉积SiO_2薄膜的光学特性

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应用光学 2011年第2期32卷 236-240页

作者：米高园朱昌戚云娟达斯坦科格拉索夫扎瓦斯基西安工业大学陕西西安710032 白俄罗斯国立信息与无线电大学白俄罗斯明斯科220013

主要研究采用离子束反应溅射(RIBS)制备SiO2薄膜的折射率、消光系数、化学计量比与氧气在氩氧混合工作气体中含量及其沉积速率的关系。研究结果表明:RIBS制备的SiO2薄膜在0.63μm处折射率n=1.48,消光系数小于10-5;随着沉积速率的增加,... 详细信息

主要研究采用离子束反应溅射(RIBS)制备SiO2薄膜的折射率、消光系数、化学计量比与氧气在氩氧混合工作气体中含量及其沉积速率的关系。研究结果表明:RIBS制备的SiO2薄膜在0.63μm处折射率n=1.48,消光系数小于10-5;随着沉积速率的增加,薄膜的折射率和消光系数随之变大,当沉积速率超过0.3 nm/s,即使是在纯氧环境溅射,折射率值也不低于1.5;通过对红外透射光谱的主吸收峰位置研究得到沉积的SiO2薄膜为缺氧型,化学计量比不超过1.8,且红外吸收峰位置和SiO2折射率存在对应关系,因此在不加热衬底情况下使用RIBS制备SiO2薄膜时,会限制沉积速率的提高。

关键词：氧化硅反应离子束溅射光学常数沉积速率

一个适用于五层北半球原始方程模式的初值化方案试验

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南京气象学院学报 1985年第1期8卷 1-16页

作者：邹晓蕾南京气象学院气象系 84届硕士研究生北京气象中心数值室

本文给出了一个适用于五层北半球原始方程模式(简称B模式)的初值化方案。首先求出北半球混合坐标系中的线性化原始方程组的垂直模,然后将客观分析风场、位势场关于这些模展开,并对由此得到的线性浅水波方程进行具有阻尼高频快波、短波... 详细信息

本文给出了一个适用于五层北半球原始方程模式(简称B模式)的初值化方案。首先求出北半球混合坐标系中的线性化原始方程组的垂直模,然后将客观分析风场、位势场关于这些模展开,并对由此得到的线性浅水波方程进行具有阻尼高频快波、短波能力的变分迭代。数值试验的结果表明,本初值化方案改善了初值处理中常见的动能损失现象。个例分析还表明,24小时各层的形势场预报比B模式有所改进,基本上克服了B模式对闭合高低压、槽脊强度预报偏弱的缺陷,24小时降水量预报加大了,更接近实况。

关键词：初值化原始方程模式初始场大气模式形势预报图变分迭代北半球

Role of endoscopic ultrasound and cyst fluid tumor markers in diagnosis of pancreatic cystic lesions

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World Journal of Gastrointestinal Endoscopy 2022年第6期14卷 402-415页

作者： Hussein Hassan Okasha Abeer Abdellatef Shaimaa Elkholy mohamad-Sherif mogawer Ayman Yosry magdy Elserafy Eman medhat Hanaa Khalaf magdy Fouad Tamer Elbaz Ahmed Ramadan mervat E Behiry Kerolis Y William Ghada Habib mona Kaddah Haitham Abdel-Hamid Amr Abou-Elmagd Ahmed Galal Wael A Abbas Ahmed Youssef Altonbary mahmoud El-Ansary Aml E Abdou Hani Haggag Tarek Ali Abdellah mohamed A Elfeki Heba Ahmed Faheem Hani m Khattab mervat El-Ansary Safia Beshir mohamed El-Nady Department of Internal medicine and Hepatogastroenterology Kasr Al-Aini HospitalsCairo UniversityKasr Al-Aini HospitalsCairo UniversityCairo 11451Egypt Department of Endemic Diseases Cairo UniversityCairo 11451Egypt Department of Tropical medicine and Gastroenterology Minia UniversityMinia 61511Egypt Department of Internal medicine Kasr Al-Aini HospitalsCairo UniversityCairo 11562Egypt Department of Gastroenterology Armed forces College of MedicineCairo 11451Egypt Endoscopy and Internal medicine Consultant at Dr/Ahmed Galal Endoscopy Center Alexandria 35516Egypt Department of Internal medicine Faculty of MedicineAssuit UniversityAssuit 71111Egypt Department of Gastroenterology and Hepatology Mansoura UniversityMansoura 35511Egypt Department of Gastroenterology and Hepatology Theodor Bilharz Research InstituteCairo 11451Egypt Department of microbiology and Immunology Faculty of Medicine for girls Al-Azhar UniversityCairo 11451Egypt Department of Internal medicine Faculty of MedicineAin shams UniversityCairo 11451Egypt Department of Internal medicine Bani-suef UniversityBani-suefBani-suef 62511Egypt Department of Pathology Faculty of MedicineCairo UniversityCairo 11451Egypt Department of Clinical Pathology Faculty of MedicineCairo UniversityCairo 11451Egypt Department of Environmental medicine&Clinical Pathology National Research CentreCairo 11451Egypt

BACKGROUND Pancreatic cystic lesions(PCLs) are common in clinical practice. The accurate classification and diagnosis of these lesions are crucial to avoid unnecessary treatment of benign lesions and missed opportunities for early treatment of potentially malignant *** To evaluate the role of cyst fluid analysis of different tumor markers such as cancer antigens [e.g., cancer antigen(CA)19-9, CA72-4], carcinoembryonic antigen(CEA), serine protease inhibitor Kazal-type 1(SPINK1), interleukin 1 beta(IL1-β), vascular endothelial growth factor A(VEGF-A), and prostaglandin E2(PGE2)], amylase, and mucin stain in diagnosing pancreatic cysts and differentiating malignant from benign *** This study included 76 patients diagnosed with PCLs using different imaging modalities. All patients underwent endoscopic ultrasound(EUS) and EUS-fine needle aspiration(EUS-FNA) for characterization and sampling of different *** The mean age of studied patients was 47.4 ± 11.4 years, with a slight female predominance(59.2%). mucin stain showed high statistical significance in predicting malignancy with a sensitivity of 87.1% and specificity of 95.56%. It also showed a positive predictive value and negative predictive value of 93.1% and 91.49%, respectively(P mucin stain, cyst fluid glucose, SPINK1, amylase, and CEA levels had high statistical significance(P analysis for prediction of malignancy in PCLs showed a statistically significant positive correlation with mural nodules, lymph nodes, cyst diameter, mucin stain, and cyst fluid CEA. meanwhile, logistic multivariable regression analysis proved that mural nodules, mucin stain, and SPINK1 were independent predictors of malignancy in cystic pancreatic *** EUS examination of cyst morphology with cytopathological analysis and cyst fluid ana

关键词： Pancreatic cystic neoplasm mucinous cystic neoplasm Intraductal papillary mucinous neoplasm mucin stain Amylase

Coasting疗法对于高反应者IVF/ICSI周期结局的影响

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世界核心医学期刊文摘（妇产科学分册） 2006年第9期2卷 44-44页

作者： Kovács P. mátyás S. Kaali S.G. 朱亮 KaáliInstitute IVF Center Istenhegyi ut 54/a 1125 BudapestHungary Dr

Objective: To investigate the effect of coasting on IVF outcome in GnRH agonist ***: Retrospective ana-lysis. Setting: Private IVF ***(s): Infertile couples undergoing IVF/intracytoplasmic sperm injection (ICSI) treatment (normal responders [control], hyper- responders [coasting]- groups).Intervention(s): Coasting to reduce the risk of ovarian hyperstimulation syndrome (OHSS) among hyper- *** Outcome measure(s): Stimulation, embryology parameters, and pregnancy rate (PR).Result(s): The average length of coasting was 2.2 *** and baseline FSH were comparable to control *** were more follicles and oocytes in the coasting group, but the number of fertilized oocytes and embryos transferred were *** rate (22.4% vs.13.9% ) was higher in the control group but the PRs were comparable (45.1% vs.38.5% ).Within the coasting group, baseline, stimulation, and embryology parameters were comparable between successful and unsuccessful *** rates were comparable after 1, 2, and 3 or more days of coasting (36.3% vs.38.4% vs.40% ). Pregnancy rates were also comparable (28.5% vs.35.7% vs.44.4% ) when groups were compared based on change in E2 ( 50% ).Conclusion(s): Coasting for 3 days can be used successfully in the management of the hyper- responding patients during IVF.

关键词：高反应者妊娠周期 IVF 疗法 ICSI 促性腺激素释放激素激动剂卵母细胞单精子显微注射卵巢过度刺激综合征

用多极理论分析圆柱-正N边形内导体同轴传输线

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微波学报 1999年第3期15卷 271-275页

作者：郑勤红伊继东马力解福瑶李梅云南师范大学物理系

本文提出用多极理论准解析计算方法分析圆柱－正Ｎ形内导体同轴传输线，介绍了多极理论的准解析计算规则。实例计算结果表明：用多极理论准解析计算方法分析圆柱－正Ｎ边形内导体同轴传输线，其计算精度是相当高的，多极理论准解析... 详细信息

本文提出用多极理论准解析计算方法分析圆柱－正Ｎ形内导体同轴传输线，介绍了多极理论的准解析计算规则。实例计算结果表明：用多极理论准解析计算方法分析圆柱－正Ｎ边形内导体同轴传输线，其计算精度是相当高的，多极理论准解析计算方法是一种较好的传输线分析方法。

关键词：多极理论准解析法正多边形内导体传输线