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Chemical and spectroscopic characterization of humic substances from sediment and riparian soil of a highly polluted urban river(Suquía River,Córdoba,Argentina)

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International Journal of Sediment Research 2020年第3期35卷 287-294页

作者： Carolina Merlo Carolina Vázquez ana graciela iriarte Carlos Matías Romero Instituto Multidisciplinario de Biologia Vegetal (CONICET) Facultad de Ciencias Agropecuarias Universidad Nacional de Cordoba INFIQC Departament of FisicoquimicaFacultad de Ciencias QuimicasUniversidad Nacional de Cordoba Agriculture and Agri-Food Canada Lethbridge Research and Development Centre Department of Biological Sciences University of Lethbridge

The Suquia River,the largest urban river in Cordoba(Argentina),has been severely polluted for *** must be taken to restore its environmental quality by managing riparian zones for increased water-self *** current study aimed to characterize organic matter(OM) dynamics and humic substances(HS) spectrochemical properties along the lower-middle basin of the Suquia *** soil(0-20 cm) and sediment(0-10 cm) samples were collected from a reference location(S1)and four polluted sites(S2-S5) during a low-flow *** contents of soil and sedimentary OM and HS fractions were analyzed by wet oxidation,as well as HS Fourier transform infrared(FT-IR) and ultraviolet-visible(UV-Vis) spectrochemical *** OM and HS fractions from riparian soil were high upstream of Cordoba City(S1 and S2,50.2-50.4 g/kg OM) and within a 50 km downstream location(S5,30.9 g/kg OM) owing to a surplus of fresh plant biomass-carbon(C) *** heterogeneous sediment samples did not show any significant differences among sites(P> 0.05).The lowest values of the ratio of absorbances at 465 and 665 nm(E4/E6)(1.78) and the Δ log K(0.15) coefficient(a measure of HS maturity degree) were obtained downstream of Cordoba City,for both riparian soil and sediment,indicating that HS were enriched by more condensed aromatic structures within highly degraded portions of the *** samples exhibited similar IR spectra,implying overlapping recalcitrant-C structures at the functional group level,but with different absorbance *** from the current study constitute a baseline for understanding the chemical nature of HS from sediment and riparian soil along the Suquia River and can be used as a reference for future studies tracking OM compositional changes over time.

关键词： Lotic ecosystems Organic matter Humic acids FT-IR spectroscopy UV-Vis spectroscopy

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AndroidCare: A Simple and Low Cost Assisted Living Solution

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Journal of Biomedical Science and Engineering 2016年第10期9卷 20-28页

作者： Abraham Otero Alejandro Escario David G. Márquez Gabriel Caffarena Rodrigo García-Carmona ana iriarte Rafael Raya Department of Information Systems Engineering University San Pablo CEU Madrid Spain

Population aging places a growing stress on society’s resources. There is a need for Assisted Living (AL) technologies that allow the elderly to live independently as long as possible. The AndroidCare open source project aims to explore what functionality can be provided in a low cost AL solution where no professional health organization is involved in the deployment or maintenance of the solution, nor in supervising the pa-tient;all these tasks are carried out by a relative of the elder. Therefore, in the system’s design simplicity of use has prevailed over having a lot of features. It is based on stan-dard off-the-shell commodity hardware (a smartphone) and it provides 1) assistance to the elder in complying with the treatment of chronic diseases;2) monitors and alerts of the occurrence of risk situations such as falls;and 3) simplifies the supervision of the elder’s therapy and behavior by the caregiver.

关键词： Assisted Living Aging Chronic Diseases Behavior Monitoring

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Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?

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World Journal of Gastroenterology 2010年第25期16卷 3144-3152页

作者： Emilia Sugai María L Moreno Hui J Hwang ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai Small Bowel Section Department of Medicine Gastroenterology Hospital "Dr. C. Bonorino Udaondo" Caseros 2061 Ciudad de Buenos Aires Argentina Pathology Service Hospital de Gastroenter-ología "Dr. C. Bonorino Udaondo" Av. Caseros 2061 Ciudad de Buenos Aires Argentina USNMA HIGA "San Martín" La Plata B1900 Provincia de Buenos Aires Argentina Endoscopy Service Hospital de Gastroenter-ología "Dr. C. Bonorino Udaondo" Av. Caseros 2061 Ciudad de Buenos Aires Argentina Endoscopy Service HIGA "San Martín" La Plata

AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects.

关键词： Celiac disease Serology Gliadin peptide antibodies Tissue transglutaminase Antigliadin antibodies Small bowel biopsy Diagnostic accuracy

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Chlamydia trachomatisin a girl suspected of sexual abuse in the city of Córdoba, Argentina

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Case Reports in Clinical Medicine 2014年第2期3卷 97-100页

作者： ana Ximena Kiguen graciela Ochonga Fernando Venezuela Marina Monetti María Celia Frutos Jessica Mosmann Cecilia Cuffini Cátedra de Odontopediatría de la Facultad de Odontología Universidad Nacional de Córdoba Córdoba Argentina Facultad de Ciencias Médicas Instituto de Virología “Dr. JM Vanella” Universidad Nacional de Córdoba Córdoba Argentina

Chlamydia trachomatis (***) infections are the most prevalent bacterial sexually transmitted infections worldwide. They are often asymptomatic and therefore underdiagnosed as there is no routine screening surveillance. This case supports the possibility of sexual abuse as a route of transmission of ***. It is well known that nearly one third of sexually assaulted children are at risk for infection by a sexually transmitted agent. This is why in cases of sexual abuse, it is standardized that *** positive results by Nucleic Acid Amplification Techniques (NAATs) should be confirmed looking for another *** target;for this reason, we used a Polimerase Chain Reaction (PCR) directed to cryptic plasmid of ***. Confirmation was specified by the use of another PCR with a different genetic target (ompA) and sequencing. We concluded that our patient’s oral lesions were probably originated by her father’s sexual abuse.

关键词： Chlamydia trachomatis Sexual Abuse Girl Argentina

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Acceptance of living liver donation among medical students: A multicenter stratified study from Spain

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World Journal of Gastroenterology 2016年第25期22卷 5800-5813页

作者： Antonio Ríos ana Isabel López-Navas ana Isabel López-López Francisco Javier Gómez Jorge iriarte Rafael Herruzo Gerardo Blanco Francisco Javier Llorca Angel Asunsolo Pilar Sánchez-Gallegos Pedro Ramón Gutiérrez ana Fernández María Teresa de Jesús Laura Martínez-Alarcón Alberto Lana Lorena Fuentes Juan Ramón Hernández Julio Virseda José Yelamos José Antonio Bondía Antonio Miguel Hernández Marco Antonio Ayala Pablo Ramírez Pascual Parrilla International Collaborative Donor Project ('Proyecto Colaborativo Internacional Donante' 30007 Casillas Murcia Spain Department of Surgery Paediatrics Obstetrics and Gynaecology University of Murcia Avenida de las Fuerzas Armadas 30800 Espinardo Murcia Spain Transplant Unit Surgery Service IMIB - Virgen de la Arrixaca University Hospital Carretera Madrid-Cartagena s/n 30120 El Palmar Murcia Spain Regional Transplant Centre Consejeria de Sanidad y Consumo de la Region de Murcia 30008 Ronda de Levante Murcia Spain Hospital Clinico Universitario Virgen de la Arrixaca Departamento de Cirugia General y del Aparato Digestivo Unidad de Trasplantes 30007 Casillas Murcia Spain Department of Psychology Universidad Catolica San Antonio (UCAM) Avenida de los Jeronimos 30107 Guadalupe Murcia Spain Department of Urology San Juan University Hospital of Alicante 03010 Calle Pintor Baeza Alicante Spain Universidad de Granada Avenida del Hospicio s/n 18010 Granada Spain Universidad de Navarra Campus Universitario 31080 Pamplona Navarra Spain Universidad Autonoma de Madrid Ciudad Universitaria de cantoblanco 28049 Madrid Spain Servicio de Cirugia HBP y Trasplante Hepatico Complejo Hospitalario Universitario de Badajoz Hospital Infanta Cristina Avenida Elvas s/n 06006 Badajoz Spain Universidad de Cantabria Avenida los Castros s/n 39005 Santander Cantabria Spain Departamento de Cirugia Ciencias Medicas y Sociales Facultad de Medicina y Ciencias de la Salud Universidad de Alcala Campus Cientifico-Tecnologico Plaza de San Diego s/n 28801 Alcala de Henares Madrid Spain Facultad de Medicina Universidad de Malaga 29071 Avenida de Cervantes Malaga Spain Servicio de Urologia (Complejo Hospitalario Universitario de Canarias CHUC) y Departamento de Cirugia (Universidad de La Laguna ULL) Calle Molinos de Agua s/n 38207 San Cristobal de La Laguna Santa Cruz de Tenerife Spain Departamento de Ciencias Biomedicas Basicas Facultad de Ciencias Biomedicas Universidad Europea de

AIM: To analyze the attitude of Spanish medical students toward living liver donation (LLD) and to establish which factors have an influence on this ***: Study type: A sociological, interdisciplinary, multicenter and observational study. Study population: Medical students enrolled in Spain (n = 34000) in the university academic year 2010-2011. Sample size: A sample of 9598 students stratified by geographical area and academic year. Instrument used to measure attitude: A validated questionnaire (PCID-DVH RIOS) was self-administered and completed anonymously. Data collection procedure: Randomly selected medical schools. The questionnaire was applied to each academic year at compulsory sessions. Statistical analysis: Student´s t test, χ2 test and logistic regression ***: The completion rate was 95.7% (n = 9275). 89% (n = 8258) were in favor of related LLD, and 32% (n = 2937) supported unrelated LLD. The following variables were associated with having a more favorable attitude: (1) age (P = 0.008); (2) sex (P < 0.001); (3) academic year (P < 0.001); (4) geographical area (P = 0.013); (5) believing in the possibility of needing a transplant oneself in the future (P < 0.001); (6) attitude toward deceased donation (P < 0.001); (7) attitude toward living kidney donation (P < 0.001); (8) acceptance of a donated liver segment from a family member if one were needed (P < 0.001); (9) having discussed the subject with one’s family (P < 0.001) and friends (P < 0.001); (10) a partner’s opinion about the subject (P < 0.001); (11) carrying out activities of an altruistic nature; and (12) fear of the possible mutilation of the body after donation (P < 0.001).CONCLUSION: Spanish medical students have a favorable attitude toward LLD.

关键词： Attitude Living liver donation Medical students Transplantation Organ donation Psychosocial variables Spain

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Multispecies Multistrain Probiotic Effects on Calves Development and Health

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Open Journal of Veterinary Medicine 2012年第4期2卷 225-229页

作者： Mirentxu Indart Silvia Cerone Eduardo Néstor Esteban Guadalupe de Yaniz ana graciela Inza Herminia Landi Silvina Mogni Leticia Igarza Department of Animal Health Faculty of Veterinary Science Universidad Nacional del Centro de la Provincia de Buenos Aires Buenos Aires Argentine Department of Animal Production Faculty of Veterinary Science Universidad Nacional del Centro de la Provincia de Buenos Aires Buenos Aires Argentine Department of Physiology and Pathology Faculty of Veterinary Medicine Universidad Nacional del Centro de la Provincia de Buenos Aires Buenos Aires Argentine

Experiment was designed to assess alimentary security or any beneficial effect on calve of a multispecies multistrain probiotic (MMP). An experiment with 36 calves, two day old, was conducted to assess the influence of probiotic on growth and health indicators. The treatment period was extended to 45 d. Group 1 received one daily dose of MMP (1.1 × 109 CFU per calf) during 20 d. Group 2 was the untreated control. On a weekly basis, every calf in each group was weighed to determine weight gain. Forty five days after the beginning of the experiment, blood samples were obtained from seven animals from Group 1 and six from Group 2, and peripheral blood neutrophils separated in order to determine metabolic and microbicidal activity. There was a significant increase in H2O2 production and NBT reduction test in MMP treated calves. The MMP not only lacks adverse effects when supplied as food additive, but showed health benefits. The prevention of infection and the highly significant increase of phagocytic activity in peripheral blood leukocytes seen in calves strongly suggest an efficient connection between the MMP and the immune system.

关键词： Probiotic Growth Health Immunology Calves

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Diagnosis and management of brain metastases:an updated review from a radiation oncology perspective

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Journal of Cancer Metastasis and Treatment 2019年第7期4卷 12-27页

作者： Gutiérrez-Valencia Enrique Sánchez-Rodríguez Irving Balderrama-Ibarra Ricardo Fuentes-LaraJesús Rios-Martínez Alan Vázquez Aldana Arroyo Iñigo Bayardo-López Luis Hernández ChávezAllan Puebla-Mora ana graciela Nader-Roa Liliana Espíritu-Rodríguez Roque Instituto Mexicano del Seguro Social(IMSS) Departamento de Radio-OncologíaCentro Médico Nacional de OccidenteUniversidad de GuadalajaraGuadalajara 44340México Instituto Mexicano del Seguro Social(IMSS) Departamento de Anatomía PatológicaCentro Médico Nacional de OccidenteUniversidad de GuadalajaraGuadalajara 44340México Instituto Mexicano del Seguro Social(IMSS) Departamento de Física MédicaCentro Médico Nacional de OccidenteGuadalajara 44340México

Brain metastasis are the most common intracranial malignancy in the adult population. Their incidence has increased dramatically over the last 20 years, as a result of the increasing number of cases stemming from lung and breast cancer together with the higher cancer survival rates due to diagnostic and therapeutic advances. More than 40%of cancer patients develop brain metastases during the course of their disease: specifically, they appear in 50%of patients with lung cancer, more than 25% of patients with breast cancer, and 20% of patients with melanoma. Diagnosis is made using different imaging approaches, such as computed tomography and magnetic resonance imaging, accompanied by clinical manifestations and a history of malignancy supporting the diagnosis of a brain metastasis. Current treatment options should be oriented to the patient's current performance, the number of intracranial and extracranial lesions, and related factors. Although surgical resection and whole-brain radiotherapy have been standard treatments for many years, numerous treatment modalities have become more easily available and accepted worldwide, producing more favorable and reliable results. Among these is stereotactic radiosurgery, and the latest clinical trials support this treatment.

关键词： Brain metastases whole-brain radiation therapy stereotactic radiosurgery graded prognostic assessment

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Secretory Structures in Flourensia campestrisand F. oolepis: Ultrastructure, Distribution, and (-)-Hamanasic Acid A Secretion

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American Journal of Plant Sciences 2015年第7期6卷 925-942页

作者： Mariana P. Silva graciela M. Tourn Daniela López Beatriz G. Galati Leonardo A. Piazza Gabriela Zarlavsky Juan J. Cantero ana L. Scopel Estación de Biología Sierras Facultad de Agronomía-Sede Punilla Universidad de Buenos Aires Casilda S/N Huerta Grande Córdoba Argentina Instituto de Investigaciones en Biociencias Agrícolas y Ambientales (INBA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) Buenos Aires Argentina Cátedra de Botánica Agrícola Facultad de Agronomía Universidad de Buenos Aires Buenos Aires Argentina Departamento de Biología Agrícola Facultad de Agronomía y Veterinaria Universidad de Río Cuarto Río Cuarto Córdoba Argentina Instituto Multidisciplinario de Biología Vegetal (CONICET-UNC) Córdoba Argentina

In this work, the localization, density, morphology and ultrastructure of secretory structures in aerial organs of Flourensia campestris (FC) and F. oolepis (FO) (Asteraceae) by means of a combination of light, fluorescence, transmission (TEM) and scanning electron microscopy (SEM) were examined. The possible role of secretory structures in the production and secretion of the phytotoxic sesquiterpene (-)-hamanasic acid A ((-)HAA) in both species was also assessed. Capitate glandular trichomes were found in all reproductive organs of FC and FO, and were being reported for the first time. These glandular trichomes, typically associated to edges and veins, were of the same type as those already described for vegetative organs, and were abundant in involucral bracts and corolla of tubulose and ligulate flowers. Their density in reproductive organs of both species was similar (ca. 30/mm2) and lower than that found in leaves (ca. 100/mm2) and stems (ca. 160/mm2 in FC, and up to 650/mm2 in FO). Glandular trichomes in vegetative organs followed a species-specific pattern of distribution. TEM and SEM observations suggest that each species differs in the way in which secretory materials are released to the outside: through cracks or pores in FC, or through a loose cuticle in FO. Similar inspections of the secretory ducts revealed lipophilic vacuoles localized in subepithelial and epithelial cells, in which secretions accumulated before being transferred to the duct. The presence of wall ingrowths in subepithelial cells suggests that granulocrine secretion operates in these species. Secretory ducts varied in density and diameter among the organs in both species, with the combination being maximal in woody stems. (-)HAA was only detected in surface secreted resins of both species, and its concentration (2D-TLC, GC-FID) was intimately associated with the distribution and density of glandular trichomes in each organ (capitula, leaves, and stems with primary or secondary growth).

关键词： Flourensia campestris Flourensia oolepis Glandular Trichomes Secretory Ducts Reproductive Organs Ultrastructure (-)-Hamanasic Acid A Resins

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Mechanism of origin in two cases of chimerism

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Open Journal of Pediatrics 2011年第4期1卷 79-86页

作者： Antonella Minelli Andrea Guala Alberto Groppo Gabriella Restagno Roberto Lala Silvia Einaudi Mariaelena Repici Emilio Merlini Luca Sbaiz Valentina Asnaghi ana graciela Lopez Paola Angellotti Silvia Cristina Cesare Danesino 不详

Chimerism is defined as the presence in a subject of more than one stable and genetically distinct cell line;cases reported so far include both patients with ambiguous genitalia and healthy subjects. The biological mechanisms, which may give origin to chimeras, are complex, and can be understood by analyzing DNA samples of the patients and their parents using molecular techniques. The objective of this study is to identify the mechanism of origin for the 2 cases we report. The first patient is a phenotipically normal girl with normal (external and internal) genitalia;the second patient had ambiguous genitalia and underwent surgery. DNA was purified from blood samples and, limited to Patient 1, from a sample of biliary cyst. Short tandem repeat polymorphisms were analyzed in order to identify the relative parental contribution to the patients. Molecular analyses carried out on the first patient are not fully informative because of two possible explanations (i.e. parthenogenetic and andrognetic chimera), while in the second case the presence of four alleles at some markers allowed us to identify a tetragametic chimera originnated from the fusion of two distinct embryos. Studies carried on one single tissue may not always be conclusive as they do not allow the precise identification of the mechanism of origin. In these cases, studies on more tissues are strongly suggested.

关键词： Chimerism Androgenetic Chimera Parthenogenetic Chimera Tetragametic Chimera Microsatellite Polymorphism analysis

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Populational Description of Patients with Diabetes Mellitus Attended in a Family Health Center in Cuiabá, Mato Grosso

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Open Journal of Endocrine and Metabolic Diseases 2017年第1期7卷 1-11页

作者： Erick Tiago de Jesus Assunç ã o ana Paula Brianezi Danyelle Mariaca de Melo Paloma de Oliveira Luciana graciela de Oliveira Boiç a Larissa Bianca Paiva Cunha de Sá Alberto Krayyem Arbex Division of Endocrinology IPEMED Medical School S&atilde o Paulo Brazil Family and Community Health Cuiabá Brazil Diabetology Department Malteser Krankenhaus St. Franziskus-Hospital Flensburg Germany

Diabetes mellitus (DM) represents one of the most serious current health problems nowadays, considering the number of people affected, its complications and morbidities. A broad analysis was performed among diabetic patients attended in the Family Health Center from the district of Baú, in Cuiabá, Mato Grosso State (Center-east Brazil), to examine the patterns of occurrence of overweight or obesity, values of glycated hemoglobin and the diagnostic of metabolic syndrome. The results show ahead a wide work that is necessary to prevent and early diagnose concerning DM, since only an intensive control will make it possible to alter the reality of the unfavorable prognosis documented.

关键词： Diabetes Mellitus Obesity Metabolic Syndrome

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