BK viral infection remains to be a challenging post-transplant infection,which can result in kidney *** mainstay approach to BK infection is reduction of *** in immunosuppressive regimen with minimization of calcineur...
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BK viral infection remains to be a challenging post-transplant infection,which can result in kidney *** mainstay approach to BK infection is reduction of *** in immunosuppressive regimen with minimization of calcineurin inhibitors,use of mechanistic target of rapamycin inhibitors,and leflunomide have been attempted with variable *** the past few years,investigators have explored potential therapeutic options for BK *** prophylaxis and treatment was found to have no benefit in kidney transplant *** utility of cidofovir is limited by its *** immunoglobulin is becoming a popular option for treatment and prophylaxis for BK infection,as it increases the neutralizing antibody titers against the most common BK virus ***-specific T cell therapy is an emerging treatment option for BK *** this review,we will explore management and therapeutic options for BK infection and recent evidence available in literature.
Dear Editor,Homeostasis and repair are critical biological processes that allow for tissue and organ preservation and function in multicellular *** regulation and extension vary drastically across the animal kingdom,a...
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Dear Editor,Homeostasis and repair are critical biological processes that allow for tissue and organ preservation and function in multicellular *** regulation and extension vary drastically across the animal kingdom,and mammals show limited tissue-specific regenerative capacity that declines with *** aging,articular cartilage is one of the tissues that undergo substantial changes in the matrix structure,molecular composition,metabolic activity,and mechanical properties(Loeser et al.2016).
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