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Male Breast Cancer:10-Year Experience at Mansoura University Hospital in Egypt

Clinical oncology and cancer researeh 2012年第1期9卷 23-28页

作者： Wafaa El-Beshbeshi Engy M abo-Elnaga Department of Clinical Oncology and Nuclear Medicine Faculty of MedicineMansoura University

Objective Male breast cancer （MBC） is a rare disease representing less than 1% of all malignancies. The objective of the study is to report clinicopathological characteristics, treatment patterns, and outcomes of MBC in Mansoura University Hospital, Egypt. Methods This retrospective study focused on male breast cancer patients during 10 years （2000-2009）. The studied variables were data regarding general characteristics of patients, treatment modalities and survival. Results The series included 37 patients （0.8% of all breast cancer）. The median age was 57.7 years （range： 26-86 years）. The main clinical complaint was a mass beneath the areola ill 94.5% of the cases. Most patients had a locally advanced disease. 94.5% of tumors were invasive duct carcinomas. The treatment was essentially surgery in 91.8%, followed by adjuvant radiotherapy （in 89.2%）, hormonal therapy （in 56.7%） and chemotherapy （in 91.8%）. Follow-up period ranged from 6-115 months. Local recurrence occurred in 4 cases and metastasis in 11 cases. The 2-year and 5-year overall survival （OS） rates were 81.6% and 60.5%, respectively. The 2-year and 5-year disease-free survival （DFS） rates were 68.4%, and 52.6%, respectively. OS was not significantly affected by any of the studied parameters. Factors influencing DFS were： T stage （P=0.05）, positive lymph nodes （P=0.043）, metastasis （P=0.004）, and chemotherapy （1＇=0.046）. Conclusions MBC is a rare disease and often diagnosed at a locally advanced stage. The management of male and female breast carcinoma is identical. Future research for better understanding of this disease is needed to improve the management and prognosis of male breast cancer patients.

关键词： breast neoplasms male therapeutics Egypt

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Molecular study of astrovirus, adenovirus and norovirus in community acquired diarrhea in children: One Egyptian center study

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 987-990页

作者： Maysaa El Sayed Zaki Nermen abo El Kheir Clinical Pathology Department Mansoura Faculty of MedicineMansoura UniversityEgypta

Objective: To determine the prevalence of astrovirus, norovirus, adenovirus in children below five years old with diarrhea by multiplex reverse transcriptase polymerase chain reaction(RT-PCR) along with rotavirus antigen detection by enzyme linked immunosorbant ***: The study was conducted on children below five years old complaining of acute diarrhea. The study included stool examination by molecular method for detection of norovirus, adenovirus and astrovirus by multiplex RT-PCR. Rotavirus antigen was detected in the stool by enzyme linked immunosorbant ***: The study included 100 children below 5 years old with acute *** RT-PCR was positive in 34% of the children. The most frequently detected virus was rotavirus(44%), followed by norovirus(30%), adenovirus(20%) and astrovirus(14%). The clinical symptoms were more significantly associated with viral diarrhea such as fever(P = 0.03), bloody diarrhea(P = 0.025), vomiting(P = 0.000 1) and watery diarrheas(P = 0.05). The frequency of diarrhea with viral pathogen was significantly presented in winter season(39.7%). There were significant frequencies of norovirus and adenovirus in age ranging 1–2 years old(P = 0.04, P = 0.01 respectively).Conclusions: The present study spotlights on the prevalence of viral pathogens as an important etiology in diarrhea in children below five years old. Astrovirus, norovirus and adenovirus are common along with rotavirus in this group of patients. Multiplex PCR leads to improve the laboratory diagnosis of these viruses along with antigen detection method. Further longitudinal studies are required to evaluate the epidemiological data associated with these viruses and for proper management of such drastic infection.

关键词： Diarrhea Astrovirus Adenovirus Norovirus Multiplex-RT PCR

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An Easy Way for Percutaneous Nephrolithotomy Using Mixed Sedative Agents

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Open Journal of Anesthesiology 2018年第7期8卷 205-213页

作者： amr M. Hilal Abdou Walid Y. Kamel Eman K. abo-Seif Department of Anesthesia Intensive Care and Pain Management Ain Shams University Cairo Egypt

Objective: We recorded the data of patients performing Percutaneous Nephro-lithotomy (PCNL) under combined spinal anesthesia with sedative mixtures of Ketamine-Propofol (KP) or Fentanyl-Propofol (FP). Background: The PCNL is usually done under General anesthesia (GA);combining spinal anesthesia with a mixture of sedative drugs has shown to provide an optimum intra and post-operative analgesic and sedative response without side effects. Patients and Methods: 100 healthy patients were enrolled for PCNL, after stabilization of the sensory block of spinal anesthesia patients were randomized into two groups;Group KP received 1 mg/Kg Ketamine and 1 mg/Kg Propofol diluted in 20 ml syringe given over 30 seconds and Group FP received 1 mic/Kg Fentanyl and 1 mg/Kg Propofol diluted in 20 ml syringe over 30 seconds;both groups will receive increment doses if the patient suffers from anxiety, pain or discomfort. Perioperative Hemodynamic data (HR, SBP, DBP, RR, and SpO2) were recorded;PACU stay time and post operative analgesia time were analyzed. Results: Sedative mixtures of FP and KP provided remarkably deep sedation levels for PCNL procedures under spinal anesthesia. Respiratory depression, hypotension and bradycardia were the major side effects reported in FP group which had mean decrease in RR of 4.63 breath/min (27.49%) with mean 3.77% drop in SpO2 levels. KP group produced significant increase in HR about 7 beats/min without reported side effects. Conclusion: Various sedation techniques may be applicable for PCNL procedures with routine premedication, mixtures of fentanyl-Propofol or Ketamine-Propofol could be used, and KP has advantages of stable hemodynamics, prolonged analgesic response intra and post-operatively with no appreciable side effects and more effective method of sedative mixture.

关键词： Nephrolithotomy Percutaneous Sedation Propofol Ketamine

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Recent advances in image processing techniques for automated leaf pest and disease recognition – A review

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Information Processing in Agriculture 2021年第1期8卷 27-51页

作者： Lawrence C.Ngugi Moataz Abelwahab Mohammed abo-Zahhad Department of Electronics and Communication Engineering Egypt-Japan University of Science and TechnologyP.O.Box 179New Borg El-Arab CityPostal Code 21934AlexandriaEgypt Department of Electrical and Electronics Engineering Assiut UniversityP.O.Box 71515AssiutEgypt

Fast and accurate plant disease detection is critical to increasing agricultural productivity in a sustainable ***,human experts have been relied upon to diagnose anomalies in plants caused by diseases,pests,nutritional deficiencies or extreme ***,this is expensive,time consuming and in some cases *** counter these challenges,research into the use of image processing techniques for plant disease recognition has become a hot research *** this paper,we provide a comprehensive review of recent studies carried out in the area of crop pest and disease recognition using image processing and machine learning *** hope that this work will be a valuable resource for researchers in this area of crop pest and disease recognition using image processing *** particular,we concentrate on the use of RGB images owing to the low cost and high availability of digital RGB *** report that recent efforts have focused on the use of deep learning instead of training shallow classifiers using handcrafted *** have reported high recognition accuracies on particular datasets but in many cases,the performance of those systems deteriorated significantly when tested on different datasets or in field ***,progress made so far has been *** results showing the leaf disease recognition performance of ten CNN architectures in terms of recognition accuracy,recall,precision,specificity,F1-score,training duration and storage requirements are also ***,recommendations are made on the most suitable architectures to deploy in conventional as well as mobile/embedded computing *** also discuss some of the unresolved challenges that need to be addressed in order to develop practical automatic plant disease recognition systems for use in field conditions.

关键词： Precision agriculture Machine learning Plant disease recognition Image processing Convolutional neural networks

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Effect of addition of chitosan to self-etching primer:antibacterial activity and push-out bond strength to radicular dentin

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The Journal of Biomedical Research 2012年第4期26卷 288-294页

作者： Shaymaa Elsaka amr Elnaghy Department of Dental Biomaterials Faculty of DentistryMansoura University Department of Conservative Dentistry and Endodontics Faculty of DentistryMansoura University

The purpose of this study was to evaluate the antibacterial activity of a modified self-etching primer incorporating chitosan and whether this modification affected the bond strength to radicular dentin.A modified self-etching primer was prepared by adding chitosan solutions at 0.03%,0.06%,0.12% and 0.25%（W/W） to RealSeal selfetching *** primer without chitosan was used as the *** antibacterial activity of the modified self-etching primer was evaluated using the direct contact test against Enterococcus *** bonding ability of the RealSeal system to radicular dentin was evaluated using the push-out bond strength *** modes of failure were examined under a *** were analyzed using analysis of variance（ANOVA） and Tukey’s test,with a P-value 〈 0.05 indicating statistical *** results showed that the antibacterial properties of the freshly prepared and aged modified self-etching primer incorporating chitosan exhibited potent antibacterial effect against Enterococcus faecalis compared with the unmodified *** RealSeal system with the aged modified self-etching primer incorporating chitosan showed no significant differences in the bond strength as compared with the control（P = 0.99）.The findings suggest that modified self-etching primer incorporating chitosan is a promising antibacterial primer which does not adversely affect the bond strength of the RealSeal system to radicular dentin.

关键词： Enterococcus faecalis antibacterial activity chitosan push-out primer radicular dentin

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