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Outsmarting Android Malware with Cutting-Edge Feature Engineering and Machine Learning Techniques

Computers, Materials & Continua 2024年第4期79卷 651-673页

作者： Ahsan Wajahat Jingsha He Nafei Zhu Tariq Mahmood Tanzila Saba amjad Rehman khan Faten S.A.lamri Faculty of Information Technology Beijing University of TechnologyBeijing100124China Artificial Intelligence and Data Analytics(AIDA)Lab CCIS Prince Sultan UniversityRiyadh11586Saudi Arabia Faculty of Information Sciences University of EducationVehari CampusVehari61100Pakistan Department of Mathematical Sciences College of SciencePrincess Nourah bint Abdulrahman UniversityRiyadh84428Saudi Arabia

The growing usage of Android smartphones has led to a significant rise in incidents of Android malware andprivacy *** escalating security concern necessitates the development of advanced technologies capableof automatically detecting andmitigatingmalicious activities in Android applications(apps).Such technologies arecrucial for safeguarding user data and maintaining the integrity of mobile devices in an increasingly digital *** methods employed to detect sensitive data leaks in Android apps are hampered by two major limitationsthey require substantial computational resources and are prone to a high frequency of false *** meansthat while attempting to identify security breaches,these methods often consume considerable processing powerand mistakenly flag benign activities as malicious,leading to inefficiencies and reduced reliability in *** proposed approach includes a data preprocessing step that removes duplicate samples,managesunbalanced datasets,corrects inconsistencies,and imputes missing values to ensure data *** Minimaxmethod is then used to normalize numerical data,followed by feature vector extraction using the Gain ratio andChi-squared test to identify and extract the most significant characteristics using an appropriate prediction *** study focuses on extracting a subset of attributes best suited for the task and recommending a predictivemodel based on domain expert *** proposed method is evaluated using Drebin and TUANDROMDdatasets containing 15,036 and 4,464 benign and malicious samples,*** empirical result shows thatthe RandomForest(RF)and Support VectorMachine(SVC)classifiers achieved impressive accuracy rates of 98.9%and 98.8%,respectively,in detecting unknown Androidmalware.A sensitivity analysis experiment was also carriedout on all three ML-based classifiers based on MAE,MSE,R2,and sensitivity parameters,resulting in a flawlessperformance for both *** app

关键词： Android malware detection machine learning SVC K-Nearest Neighbors(KNN) RF

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Image Fusion Using Wavelet Transformation and XGboost Algorithm

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Computers, Materials & Continua 2024年第4期79卷 801-817页

作者： Shahid Naseem Tariq Mahmood amjad Rehman khan Umer Farooq Samra Nawazish Faten S.Alamri Tanzila Saba Department of Information Sciences Division of S&TUniversity of EducationLahore54770Pakistan Artificial Intelligence and Data Analytics(AIDA)Lab CCIS Prince Sultan UniversityRiyadh11586Saudi Arabia Faculty of Information Sciences University of EducationVehari CampusVehari61100Pakistan Department of Computer Science University of Engineering and TechnologyTaxila47050Pakistan Department of Mathematical Sciences College of SciencePrincess Nourah Bint Abdulrahman UniversityRiyadh84428Saudi Arabia

Recently,there have been several uses for digital image *** fusion has become a prominent application in the domain of imaging *** create one final image that provesmore informative and helpful compared to the original input images,image fusion merges two or more initial images of the same *** fusion aims to produce,enhance,and transform significant elements of the source images into combined images for the sake of human visual *** fusion is commonly employed for feature extraction in smart robots,clinical imaging,audiovisual camera integration,manufacturing process monitoring,electronic circuit design,advanced device diagnostics,and intelligent assembly line robots,with image quality varying depending on *** research paper presents various methods for merging images in spatial and frequency domains,including a blend of stable and curvelet transformations,everageMax-Min,weighted principal component analysis(PCA),HIS(Hue,Intensity,Saturation),wavelet transform,discrete cosine transform(DCT),dual-tree Complex Wavelet Transform(CWT),and multiple wavelet *** fusion methods integrate data from several source images of an identical target,thereby enhancing information in an extremely efficient *** precisely,in imaging techniques,the depth of field constraint precludes images from focusing on every object,leading to the exclusion of certain *** tackle thess challanges,a very efficient multi-focus wavelet decomposition and recompositionmethod is *** use of these wavelet decomposition and recomposition techniques enables this method to make use of existing optimized wavelet code and filter *** simulated outcomes provide evidence that the suggested approach initially extracts particular characteristics from images in order to accurately reflect the level of clarity portrayed in the original *** study enhances the performance of the eXtreme Gradient Boosting(XGBoos

关键词： Image fusion max-min average CWT XGBoost DCT inclusive innovations spatial and frequency domain

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Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function variants in TMEM141,DDHD2,and LHFPL5

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Frontiers of Medicine 2024年第1期18卷 81-97页

作者： Liwei Sun Xueting Yang amjad khan Xue Yu Han Zhang Shirui Han Xiaerbati Habulieti Yang Sun Rongrong Wang Xue Zhang McKusick-Zhang Center for Genetic Medicine State Key Laboratory for Complex Severe and Rare DiseasesInstitute of Basic Medical Sciences Chinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical CollegeBeijing100005China Chongqing Key Laboratory of Human Embryo Engineering Center for Reproductive MedicineNational Key Clinical Speciality Construction Project(Obstetrics and Gynecology)Chongqing Health Center for Women and ChildrenChongqing400013China Chongqing Clinical Research Center for Reproductive Medicine Women and Children’s Hospital of Chongqing Medical UniversityChongqing400013China Faculty of Biological Sciences Department of ZoologyUniversity of Lakki MarwatKhyber Pakhtunkhwa28420Pakistan Institute for Medical Genetics and Applied Genomics University of TübingenTübingen72076Germany Alexander von Humboldt fellowship Foundation Berlin10117Germany Department of Pediatrics The First Affiliated Hospital of Guangxi Medical UniversityNanning530000China Department of Laboratory Medicine State Key Laboratory for Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing100730China

Highly clinical and genetic heterogeneity of neurodevelopmental disorders presents a major challenge in clinical genetics and *** variation analysis is imperative to analyze the disease phenotypes resulting from multilocus genomic ***,a Pakistani family with parental consanguinity was presented,characterized with severe intellectual disability(ID),spastic paraplegia,and *** mapping,integrated single nucleotide polymorphism(SNP)array,whole-exome sequencing,and whole-genome sequencing were performed,and homozygous variants in TMEM141(c.270G>A,***90^(*)),DDHD2(c.411+767_c.1249-327del),and LHFPL5(c.250delC,***84^(*))were identified.A Tmem141^(***90^(*)/***90^(*))mouse model was *** studies showed impairments in learning ability and motor *** slice electrophysiology and Golgi staining demonstrated deficient synaptic plasticity in hippocampal neurons and abnormal dendritic branching in cerebellar Purkinje *** electron microscopy showed abnormal mitochondrial ***,studies on a human in vitro neuronal model(SH-SY5Y cells)with stable shRNA-mediated knockdown of TMEM141 showed deleterious effect on bioenergetic function,possibly explaining the pathogenesis of replicated phenotypes in the cross-species mouse ***,panoramic variation analysis revealed that multilocus genomic variations of TMEM141,DDHD2,and LHFPL5 together caused variable phenotypes in ***,the biallelic loss-of-function variants of TMEM141 were responsible for syndromic ID.

关键词： neurodevelopmental disorder autosomal recessive intellectual disability consanguinity spastic paraplegia hearing loss TMEM141

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Potential of plant polyphenol oxidases in the decolorization and removal of textile and non-textile dyes

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Journal of Environmental Sciences 2007年第4期19卷 396-402页

作者： amjad ALI khan QAYYUM Husain Department of Biochemistry Faculty of Life Science Aligarh Muslim UniversityAligarh-202 002India.

In this study an effort has been made to use plant polyphenol oxidases; potato （Solanum tuberosum） and brinjal （Solanum melongena）, for the treatment of various important dyes used in textile and other industries. The ammonium sulphate fractionated enzyme preparations were used to treat a number of dyes under various experimental conditions. Majority of the treated dyes were maximally decolorized at pH 3.0. Some of the dyes were quickly decolorized whereas others were marginally decolorized. The initial first hour was sufficient for the maximum decolorization of dyes. The rate of decolorization was quite slow on long treatment of dyes. Enhancement in the dye decolorization was noticed on increasing the concentration of enzymes. The complex mixtures of dyes were treated with both preparations of polyphenol oxidases in the buffers of varying pH values. Potato polyphenol oxidase was significantly more effective in decolorizing the dyes to higher extent as compared to the enzyme obtained from brinjal polyphenol oxidase. Decolorization of dyes and their mixtures, followed by the formation of an insoluble precipitate, which could be easily removed simply by centrifugation.

关键词： decolorization textile dyes polyphenol oxidases potato brinjal wastewater treatment removal of dyes

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Properties of Exponential Ratio Type Estimators in Equal Probability Sampling: A Simulation Study

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Communications in Mathematics and Statistics 2018年第1期6卷 91-118页

作者： Hina khan Muhammad Aslam Masood amjad khan Department of Statistics GC UniversityLahorePakistan Department of Statistics Faculty of ScienceKing Abdulaziz UniversityJeddah 21551Saudi Arabia

In this paper,the properties and goodness of fit of exponential ratio type estimatorproposedbykhanetal.(SciInt(Lahore)26(5):1897–1902,2014)havebeen carried out through *** has been shown that estimator is consistent;the con-vergence of mean and variance of the estimator are *** properties of some existing estimators based on simulation study have also been *** of fit test on the estimator has been carried out using Kolmogorov–Smirnov,Anderson–Darling,Cramer–von *** as normal,Student t,Weibull and Cauchy distributions are fitted on the *** best-fitted distribution on the estimator turned out to be normal distribution.

关键词： Goodness of fit Distribution Skewed Consistent Convergence

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Enhanced photocatalytic degradation of organic dyes from aqueous environment using neodymium-doped mesoporous layered double hydroxide

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Journal of Rare Earths 2022年第10期40卷 1554-1563页

作者： Ajaz Ahmad Wani amjad Mumtaz khan Yahiya Kadaf Manea Mansour A.S.Salem Department of Chemistry Aligarh Muslim UniversityAMUAligarh202002India

Neodymium-doped Zn-Al layered double hydroxide(Nd/Zn-Al LDH) with excellent photocatalytic activity was prepared by a one-step hydrothermal method. The morphology and physicochemical properties of as-synthesized photocatalysts were well analyzed by Fourier transform infrared(FT-IR), X-ray diffraction(XRD), scanning electron microscopy(SEM), transmission electron microscopy(TEM), photoluminescence(PL), UV-diffuse reflectance spectroscopy(UV-DRS), and Brunauer-Emmett-Teller(BET)surface analysis. Doping Nd^(3+) into Zn-Al LDH enhances the overall catalytic activity of the nanocomposite, like better electron-hole pair separation, increase in interplanar distance, fast electron transfer, and large surface area. The as-prepared nanocomposite shows excellent degradation of three different dyes under visible light irradiation. The degradation efficiency of these dyes follows the order of Congo red > rose Bengal > fast green. Furthermore, liquid chromatography-mass spectrometry(LC-MS)was employed to propose a possible photocatalytic degradation pathway for Congo Red and Rose Bengal dyes by Nd/Zn-Al LDH. With the help of radical trapping experiments, it is revealed that during the photoexcitation process, the primary reactive intermediates are hydroxyl radicals.

关键词： Organic pollutants Degradation Multifunctional Mesoporous LC-MS Rare earths

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Anticipating the lifespan: Predicting the durability of an anode-supported solid oxide fuel cell short stack over 50,000 h

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Progress in Natural Science:Materials International 2024年第3期34卷 606-613页

作者： Muhammad Zubair khan amjad Hussain Seung-Bok Lee Tak-Hyoung Lim Rak-Hyun Song Department of Materials Science & Engineering Pak-Austria Fachhochschule: Institute of Applied Sciences and Technology Hydrogen Energy Research Division Korea Institute of Energy Research Department of Advanced Energy and System Engineering Korea University of Science and Technology (UST)

In the present study, the operational lifetime of a solid oxide fuel(SOFC) short stack is predicted by investigating the performance degradation of both the short stack and its cells throughout 1000 h at 800°C. The short stack and integral cell voltages are continuously measured during the long-term test, with electrochemical impedance spectroscopy(EIS) conducted every 200 h. The short stack voltage decreased rapidly for the initial 200–300 h and afterwards, it decreased at a slow rate due to the increase in the Ohmic and polarization resistances in the same manner. Scanning electron microscopy results show that there is no delamination or cracking among constituent layers of the short-stack cells. The single degradation effects of the Ni coarsening in the anode, cation migration and surface segregation in cathode and oxide scale growth in metallic interconnect mesh are successfully integrated into a comprehensive lifetime prediction model. The experimentally measured voltage degradation data of the short stack fits well with the developed mathematical model and allows the successful prediction of the lifetime up to 50,000 h.

关键词： SOFC Stack Degradation Impedance Lifetime

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Current updates of CRISPR/Cas9-mediated genome editing and targeting within tumor cells:an innovative strategy of cancer management

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Cancer Communications 2022年第12期42卷 1257-1287页

作者： Khaled S.Allemailem Mohammed A Alsahli Ahmad Almatroudi Faris Alrumaihi Fahd Khaleefah Alkhaleefah Arshad Husain Rahmani amjad Ali khan Department of Medical Laboratories College of Applied Medical SciencesQassim UniversityBuraydahSaudi Arabia Department of Laboratory and Blood Bank Al Rass General HospitalAl RassSaudi Arabia Department of Basic Health Sciences College of Applied Medical SciencesQassim UniversityBuraydahSaudi Arabia

Clustered regularly interspaced short palindromic repeats-associated protein(CRISPR/Cas9),an adaptive microbial immune system,has been exploited as a robust,accurate,efficient and programmable method for genome targeting and *** innovative and revolutionary technique can play a significant role in animal modeling,in vivo genome therapy,engineered cell therapy,cancer diagnosis and *** CRISPR/Cas9 endonuclease system targets a specific genomic locus by single guide RNA(sgRNA),forming a heteroduplex with target *** Streptococcus pyogenes Cas9/sgRNA:DNA complex reveals a bilobed architecture with target recognition and nuclease ***/Cas9 assembly can be hijacked,and its nanoformulation can be engineered as a delivery system for different clinical ***,the efficient and safe delivery of the CRISPR/Cas9 system to target tissues and cancer cells is very challenging,limiting its clinical *** delivery strategies of this system may have many advantages,but disadvantages such as immune system stimulation,tumor promotion risk and small insertion size outweigh these ***,there is a desperate need to develop an efficient non-viral physical delivery system based on simple *** delivery strategies of CRISPR/Cas9 by a nanoparticle-based system have shown tremendous potential,such as easy and large-scale production,combination therapy,large insertion size and efficient in vivo *** review aims to provide in-depth updates on Streptococcus pyogenic CRISPR/Cas9 structure and its mechanistic *** addition,the advances in its nanoformulation-based delivery systems,including lipid-based,polymeric structures and rigid NPs coupled to special ligands such as aptamers,TAT peptides and cell-penetrating peptides,are ***,the clinical applications in different cancers,clinical trials and future prospects of CRISPR/Cas9 delivery and genome targeting are also discussed.

关键词： cancer clinical trials CRISPR/Cas9 genome editing mechanism nanoparticles structure

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A Review of Structure Activity Relationship of Amiodarone and Its Derivatives

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Open Journal of Medicinal Chemistry 2016年第2期6卷 37-42页

作者： Moiz A. Siddiqui amjad khan Mehreen Zaka Department of Chemistry Angels International College Faisalabad Pakistan Discipline of Clinical Pharmacy School of Pharmaceutical Sciences University Sains Malaysia Penang Malaysia Department of Biotechnology Quaid-i-Azam University Islamabad Pakistan

Structure Activity Relationship forms the basis of Rational Drug Design in the circles of pharmaceutical and medicinal chemistry. Appropriate knowledge of functional outcomes of structural modifications is crucial in conferring desired pharmacological properties to a chemical compound. Amiodarone is a classical antiarrythmic agent with a long list of adverse effects. This article attempts to review the structure activity relationship of some of the homologues of amiodarone in order to determine the most clinically desirable molecule.

关键词： Amiodarone Dronedarone Structure-Activity-Relationship

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Validity of the patient health questionnaires(phq-2 and phq-9)for screening depression among human immunodeficiency virus patients in Lahore,Pakistan

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World Journal of Virology 2022年第5期11卷 341-351页

作者： Khunsa Junaid Iqra Akram Muhammad Daood amjad khan Department of Community Medicine King Edward Medical UniversityLahore 54000Punjab ProvincePakistan Department of Pulmonology General HospitalLahore 54000Punjab ProvincePakistan Department of Public Health and Nutrition the University of HaripurHaripur 22781Khyber PakhtunkhwaPakistan

BACKGROUND Many human immunodeficiency virus(HIV)infected patients suffer from depression,but a little focus is given to detecting and treating depression in primary health *** of depression can be improved by introducing short,reliable,and valid screening *** To determine the psychometric properties of the patient health questionnaire-2(PHQ-2)and patient health questionnaire-9(PHQ-9)for depression screening and diagnosis,and the sensitivity and specificity of the PHQ-2 in HIV infected *** A cross-sectional study was conducted on 158 HIV-infected patients aged 18 years and above in Lahore,***-2 was implemented to screen ***-9 was implemented to diagnose major depressive disorder as a reference ***,Validity tests and receiver operating characteristic curve were *** The Cronbach's alpha of PHQ-2 and PHQ-9 were 0.732 and 0.759,*** study results showed that the score of 2 on PHQ-2 indicates the highest Youden's index of 0.924,with both sensitivity and specificity of 0.96,and the area under the curve for PHQ-2 was 0.98(95%CI:0.953-0.998).CONCLUSION Good psychometric properties for the PHQ-2 and PHQ-9 indicated their significant potential as tools for depression screening and diagnosis in the HIV-infected population.

关键词： Depression Validity Patient health questionnaire-9 Patient health questionnaire-2 HIV/AIDS Lahore Pakistan

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