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Management of hypersplenism in non-cirrhotic portal hypertension:a surgical series

Hepatobiliary & Pancreatic Diseases International 2012年第2期11卷 165-171页

作者： Rajesh Rajalingam amit Javed Dharmanjay Sharma Puja Sak.uja Shivendra Singh Hirdaya H Nag Anil k.agarwal Department of Gastrointestinal Surgery G. B. Pant Hospital and Maulana Azad Medical College Delhi University New Delhi India Department of Pathology G. B. Pant Hospital and Maulana Azad Medical College Delhi University New Delhi India

BACk.ROUND:Hypersplenism is commonly seen in patients with non-cirrhotic portal hypertension(NCPH).While a splenectomy alone can effectively relieve the hypersplenism,it does not address the underlying portal *** present study was undertak.n to analyze the impact of shunt and non-shunt operations on the resolution of hypersplenism in patients with *** relationship of symptomatic hypersplenism,severe hypersplenism and number of peripheral cell line defects to the severity of portal hypertension and outcome was also ***:A retrospective analysis of NCPH patients with hypersplenism managed surgically between 1999 and 2009 at our center was *** 252 patients with NCPH,64(45 with extrahepatic portal vein obstruction and 19 with non-cirrhotic portal fibrosis) had hypersplenism and constituted the study *** analysis was done using GraphPad *** and continuous variables were compared using the chi-square test,ANOVA,and Student’s t *** MannWhitney U test and k.usk.l-Wallis test were used to compare non-parametric ***:The mean age of patients in the study group was 21.81±6.1 *** was symptomatic in 70.3% with an incidence of spontaneous bleeding at 26.5%,recurrent anemia at 34.4%,and recurrent infection at 29.7%.The mean duration of surgery was 4.16±1.9 hours,intraoperative blood loss was 457±126(50-2000) mL,and postoperative hospital stay 5.5±1.9 *** surgery,normalization of hypersplenism occurred in all *** long-term followup,none of the patients developed hepatic encephalopathy and 4 had a variceal re-bleeding(2 after a splenectomy alone,1 each after an esophago-gastric devascularization and proximal splenorenal shunt).Patients with severe hypersplenism and those with defects in all three peripheral blood cell lineages were older,had a longer duration of symptoms,and a higher incidence of variceal bleeding and postoperative *** addition,patients with t

关键词： portal hypertension hypersplenism splenorenal shunt lienorenal shunt

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富氮低氧+磷化氢防治储粮害虫技术的实仓应用研究

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粮油食品科技 2024年第3期32卷 39-54页

作者： Manjree agarwal James NEWMAN Yan-yu LI Li GU Bei-bei LI Sucharita BASAVARAJAPP Yong-lin REN 李燕羽(译) 西澳大利亚州政府化学中心澳大利亚珀斯WA 6102 CBH澳大利亚谷物有限公司澳大利亚珀斯WA 6000 默多克大学环境和生命科学学院澳大利亚珀斯WA 6150 国家粮食和物资储备局科学研究院粮食储运研究所北京100037 国家粮食和物资储备局科学研究院粮食储运研究所

为防治澳大利亚主要仓储害虫,开发富氮气调技术作为熏蒸剂的辅助手段。然而,由于成本问题,一直影响其在行业推广应用。本研究利用中国长顺安达公司的先进膜分离技术,与传统的制氮技术(变压吸附/PSA)进行性能比较,在西澳k.inana的CBH粮食... 详细信息

为防治澳大利亚主要仓储害虫,开发富氮气调技术作为熏蒸剂的辅助手段。然而,由于成本问题,一直影响其在行业推广应用。本研究利用中国长顺安达公司的先进膜分离技术,与传统的制氮技术(变压吸附/PSA)进行性能比较,在西澳k.inana的CBH粮食港,开展实仓应用实验,以解决阻碍其推广的运营和成本问题。为满足澳大利亚严格的标准操作条件,长顺安达专业团队对港口设备进行了升级改造,目标消杀成本设定为0.50澳元/吨粮(磷化氢的高端熏蒸成本)。研究表明,旧的PSA技术的运营成本为2.43澳元/吨粮,该技术在产生和维持控制害虫所需的99%氮气浓度水平方面也显示出操作局限性。相比之下,使用膜技术制氮的成本为0.99澳元/吨粮,其他性能增益还包括运行4.5天内即可产生所需的氮气浓度,且可维持14天以完全控制害虫。

关键词：粮食储藏储粮害虫管理氮气储藏变压吸附制氮机膜分离制氮机

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Annealing-induced long-range charge density wave order in magnetic k.gome FeGe:Fluctuations and disordered structure

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Science China(Physics,Mechanics & Astronomy) 2024年第11期67卷 112-121页

作者： Chenfei Shi Yi Liu Bishal Baran Maity Qi Wang Surya Rohith k.tla Sitaram Ramak.ishnan Claudio Eisele Harshit agarwal Leila Noohinejad Qian Tao Baojuan k.ng Zhefeng Lou Xiaohui Yang Yanpeng Qi Xiao Lin Zhu-An Xu Arumugam Thamizhavel Guang-Han Cao Sander Van Smaalen Shixun Cao Jin-k. Bao Department of Physics Materials Genome InstituteInstitute for Quantum Science and TechnologyShanghai UniversityShanghai 200444China k.y Laboratory of Quantum Precision Measurement of Zhejiang Province School of PhysicsZhejiang University of TechnologyHangzhou 310023China School of Physics Zhejiang UniversityHangzhou 310027China Department of Condensed Matter Physics and Materials Science Tata Institute of Fundamental ResearchMumbai 400005India School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China ShanghaiTech Laboratory for Topological Physics ShanghaiTech UniversityShanghai 201210China Laboratory of Crystallography University of BayreuthBayreuth 95447Germany Department of Quantum Matter AdSEHiroshima UniversityHigashi-Hiroshima 739-8530Japan P24 PETRA IIIDeutsches Elektronen-Synchrotron DESYHamburg 22607Germany k.y Laboratory for Quantum Materials of Zhejiang Province School of ScienceWestlake UniversityHangzhou 310024China Department of Physics China Jiliang UniversityHangzhou 310018China Shanghai k.y Laboratory of High-resolution Electron Microscopy ShanghaiTech UniversityShanghai 201210China Collaborative Innovation Centre of Advanced Microstructures Nanjing UniversityNanjing 210093China Shanghai k.y Laboratory of High Temperature Superconductors Shanghai UniversityShanghai 200444China School of Physics Hangzhou Normal UniversityHangzhou 311121China

Charge density wave(CDW) in k.gome materials with the geometric frustration is able to carry unconventional ***, a CDW has been observed below the antiferromagnetic order in k.gome FeGe, in which magnetism and CDW are intertwined to form an emergent quantum ground state. However, the CDW is only short-ranged and the structural modulation originating from it has yet to be determined experimentally. Here we realize a long-range CDW order by post-annealing process,and resolve the structure model through single crystal X-ray diffraction. Occupational disorder of Ge resulting from short-range CDW correlations above T_(CDW) is identified from structure refinements. The partial dimerization of Ge along the c axis is unveiled to be the dominant distortion for the CDW. Occupational disorder of Ge is also proved to exist in the CDW phase due to the random selection of partially dimerized Ge sites. Our work.provides useful insights for understanding the unconventional nature of the CDW in FeGe.

关键词： charge density wave k.gome disordered structure fluctuations

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Role　of　Triad　k.netic　Energy　Interactions　for　Maintenance　of　Upper　Tropospheric　Low　Frequency　Waves　during　Summer　Monsoon　　1988

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Advances in Atmospheric Sciences 1996年第1期13卷 91-102页

作者： D. R. Chak.aborty N. k. agarwal Indian Institute of Tropical Meteorology Pune

In order to determine nonlinear energy exchanges into individual triad interactions in the frequency domain,spectral formulas are derived by use of the cross-spectral technique. First time attempt has been made to understandthe problem of maintenance of low frequency waves for tropical weather system by using this *** TOGAbasic level ill daily wind analyses on a 2.5 degree square grid around the global zone from 20°S-30°N at 200 hpa for92-day periods covering June, July and August of 1988 are used. k.netic energy is gained at high frequencies and lostat low *** the planetary scale dynamics over tropics, barotropic nonlinear energy transfer plays a *** frequency wave of period 45 day loses maximum amount of energy when it interacted with frequencies ofperiods 92 day and 30 day.45 day cycle is also the main source of energy for other frequencies. Distrubances of periodl 5 day gain maximum amount of *** major contribution comes from the triad interaction of the frequencies.North of 20'N low frequency waves of period 30 to 92--day gain energy through nonlinear triadinteraction with the maximum gain at 22.5'N. The study may help to investigate the rapid loss of predictability of lowfrequency modes over tropics.

关键词： Cross spectral technique Low frequency mode

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Randomized controlled trial of topical EMLA and vapocoolant spray for reducing pain during wDPT vaccination

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World Journal of Pediatrics 2017年第3期13卷 236-241页

作者： Navratan k.mar Gupta amit Upadhyay Ajeet k.mar Dwivedi Astha agarwal Vijay Jaiswal Abhishek.Singh Department of Pediatrics LLRMMedical CollegeMeerut(UP)India

Back.round:Intramuscular vaccination is among the most common source of iatrogenic pain in *** sprays are rapid-acting alternative to topical *** provide transient anesthesia via evaporation induced sk.n cooling,and reduce pain due to vaccine injection in children and *** objective was to compare the synergistic analgesic effect of eutectic mixture of local anesthetics (EMLA) with breastfeeding (EB group) and vapocoolant spay with breastfeeding (VB group) to that of only breastfeeding (BO group) during whole cell diptheria,pertussis and tetanus (wDPT) ***:A double blind randomized controlled trial was done to include infants up to 3 months of age who came for their first wDPT *** primary outcome variable was the duration of cry after *** outcome variables were Modified Facial Coding Score,Neonatal Infant Pain Scale and latency of onset of ***:Of the 201 eligible participants,111 babies were excluded and remaining 90 babies were randomized into three groups of thirty *** groups did not differ significantly in baseline *** (interquartile range,IQR) of duration of cry was lesser [35.86 (21.07-107.75) seconds] in babies receiving EMLA cream with breast feeding (EB group) and in babies receiving vapocoolant spray with breast feeding (VB group) [32.58 (21.25-106.21) seconds] as compared to babies receiving only breast feeding (BO group) [67.5 (27.6-180) seconds] (P=-0.147).Difference in median (IQR) of latency of cry was not statistically *** Facial Coding Score and Neonatal Infant Pain Scale at 1 minute and 3 minutes was significantly lower in the EB and VB group,as compared to the BO group (P<0.05).Conclusions:Addition of topical EMLA application or vapocoolant spray to breastfeeding during wDPT vaccination does not reduce duration of cry in infants up to 3 months of ***,they are able to show reduction in pain score and further studi

关键词： diptheria,pertussis and tetanus vaccine eutectic mixture of local anesthetics Modified Facial Coding Score Neonatal Infant Pain Scale

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A Hierarchical Reconfiguration Strategy for Bus-Based Multiprocessors

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Journal of Computer Science & Technology 1990年第2期5卷 175-186页

作者： Ashish Pancholy Fidel Muradali Vinod k.agarwal VLSI Design Laboratory Department of ElectricalEngineeringMcGill University

A method of providing redundancy to a class of bus-based multiprocessor arrays is *** reconfiguration is hierarchical,providing global spare replacement at the array level and local reconfiguration within the spare **... 详细信息

关键词： A Hierarchical Reconfiguration Strategy for Bus-Based Multiprocessors PE

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Magnetic and magnetotransport behavior of overdoped nanocrystalline Nd_(1-x)Sr_xMnO_3 (0.50≤x≤0.63)

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Journal of Rare Earths 2011年第7期29卷 654-659页

作者： Neelam Maik.uri Vasudha agarwal Anurag Gaur H.k.Singh Department of Physics National Institute of Technology Kurukshetra-136119 India National Physical Laboratory New Delhi-110012 India

The nanocrystalline samples of Nd1-xSrxMnO3 （NSMO）（x=0.5, 0.55, 0.60, 0.63） were synthesized by sol-gel based polymeric pre-cursor route. Structural, magnetic and magnetotransport properties were studied systematically. It was found that in the composition range （x=0.50-0.63）, Nd1-xSrxMnO3 showed paramagnetic to ferromagnetic （PM-FM） transition in the vicinity of TC～270 k.but the FM phase was weak.ned as the Sr concentration increased. The appearance of weak.ferromagnetism was explained in terms of the core-shell model. More-over, for x=0.63 sample, a second transition is observed below TC at T=185 k. which is possibly due to the appearance of A-AFM/ C-AFM or a mixture of both the phases. Resistivity vs temperature （ρ-T） curve showed that the resistivity of all the samples was much larger than the sin-gle crystals of corresponding compositions due to large contribution of the grain boundaries in the present nanocrystalline samples. In all samples, extrinsic k.nd of MR behavior dominated because of nanocrystalline nature of the samples, which was nearly of the same order （～10%） in all samples. However, the intrinsic k.nd of MR behavior was also significant in x=0.50 sample, because of the strongest FM feature in this sample.

关键词： manganites magnetoresistance spin polarized tunnelling rare earths

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Sperm DNA damage and its clinical relevance in assessingreproductive outcome

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Asian Journal of Andrology 2004年第2期6卷 139-148页

作者： R. k. Sharma T. Said A. agarwal Centerfor Advanced Research in Human Reproduction Infertility and Sexual Function Glickman Urological Institute The Cleveland Clinic Foundation Cleveland Ohio 44195 USA

The routine examination of semen, which assesses sperm concentration, percentage motility and morphology, does not identify subtle defects in sperm chromatin architecture. The focus on the genomic integrity of the male gamete has intensified recently due to the growing concern that genetic diseases may be transmitted via assisted reproductive techniques (ART). Accordingly, the intent of this review is to describe the details of the information pertaining to mitochondrial/nuclear sperm DNA damage with an emphasis on its clinical significance and its relation ship with male infertility. Assessment of sperm DNA damage appears to be a potential tool for evaluating semen samples prior to their use in ART. Testing DNA integrity may help select spermatozoa with intact DNA or with the least amount of DNA damage for use in assisted conception. In turn, this may alleviate the financial, social and emotional problems associated with failed ART attempts.

关键词： DNA damage human male infertility sperm

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Xanthogranulomatous cholecystitis:a premalignant condition?

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Hepatobiliary & Pancreatic Diseases International 2011年第2期10卷 179-184页

作者： Mila Ghosh Puja Sak.uja Anil k.agarwal Department of Gastrointestinal Surgery GB Pant Hospita and Maulana Azad Medical College Department of Pathology GB Pant Hospita and Maulana Azad Medical College

BACk.ROUND:Xanthogranulomatous cholecystitis(XGC)is an uncommon variant of chronic cholecystitis,characterized by mark.d thick.ning of the gallbladder wall and dense local *** often mimics a gallbladder carcinoma(GBC), and may coexist with GBC,leading to a diagnostic dilemma. Furthermore,the premalignant nature of this entity is not *** study was undertak.n to assess the p53,PCNA and beta-catenin expression in XGC in comparison to GBC and chronic inflammation. METHODS:Sections from paraffin-embedded block. of surgically resected specimens of GBC(69 cases),XGC(65), chronic cholecystitis(18)and control gallbladder(10)were stained with the monoclonal antibodies to p53 and PCNA, and a polyclonal antibody to beta-catenin.p53 expression was scored as the percentage of nuclei *** expression was scored as the product of the percentage of nuclei stained and the intensity of the staining(1-3).A cut-off value of 80 for this score was tak.n as a positive result. Beta-catenin expression was scored as type of expression-membranous,cytoplasmic or nuclear staining. RESULTS:p53 mutation was positive in 52%of GBC cases and 3%of XGC,but was not expressed in chronic cholecystitis and control gallbladders.p53 expression was lower in XGC than in GBC(P<0.0001).PCNA expression was seen in 65%of GBC cases and 11%of XGC,but not in chronic cholecystitis and control *** expression was higher in GBC than XGC(P=0.0001),but there was no significant difference between the XGC,chronic cholecystitis and control gallbladder ***-catenin expression was positive in the GBC,XGC, chronic cholecystitis and control gallbladder *** the expression pattern in XGC,chronic cholecystitis and control gallbladders was homogenously membranous,whereas in GBC the membranous expression pattern was altered to cytoplasmic and ***:The expression of p53,PCNA and beta-catenin in XGC was significantly different from GBC and similar to chronic cholecystitis,

关键词： xanthogranulomatous cholecystitis gallbladder cancer p53 PCNA beta-catenin

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Endoscopic management of acute cholangitis in elderly patients

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World Journal of Gastroenterology 2006年第40期12卷 6551-6555页

作者： Naresh agarwal Barjesh Chander Sharma Shiv k.Sarin Department of Gastroenterology GB Pant Hospital New Delhi India

AIM: To evaluate clinical presentation, etiology, compli-cations and response to treatment in elderly patients with acute ***: Demographics, etiology of biliary obstruc-tion, clinical features, complications and associated systemic diseases of 175 patients with acute cholangitis were recorded. Endoscopic biliary drainage was performed using nasobiliary drain or stent. The complications related to ERCP, success of biliary drainage, morbidity, mortality and length of hospital stay were evaluated. RESULTS: Of 175 patients, 52 aged ≥ 60 years (groupⅠ, age < 60 years; group Ⅱ, age ≥ 60 years) and 105 were men. Fever was present in 38 of 52 patients of group Ⅱ compared to 120 of 123 in groupⅠ. High fever (fever ≥ 38.0℃) was more common in groupⅠ(118/120 vs 18/38). Hypotension (5/123 vs 13/52), altered sensorium (3/123 vs 19/52), peritonism (22/123 vs 14/52), renal failure (5/123 vs 14/52) and associated comorbid diseases (4/123 vs 21/52) were more common in group Ⅱ. Biliopancreatic malignancy was a common cause of biliary obstruction in group Ⅱ (n = 34) and benign diseases in groupⅠ(n = 120). Indications for biliary drainage were any one of the following either singly or in combination: a fever of ≥ 38.0℃ (n = 136), hypotension (n = 18), peritonism (n = 36), altered sensorium (n = 22), and failure to improve within 72 h of conservative management (n = 22). High grade fever was more common indication of biliary drainage in groupⅠand hypotension, altered sensorium, peritonism and failure to improve within 72 h of conservative management were more common indications in group Ⅱ. Endoscopic biliary drainage was achieved in 172 patients (nasobiliary drain: 56 groupⅠ, 24 group Ⅱ, stent: 64 groupⅠ, 28 group Ⅱ) without any significant age related difference in the success rate. Abdominalpain, fever, jaundice, hypotension, altered sensorium, peritonism and renal failure improved after median time of 5 d in 120 patients in groupⅠ(2-15 d) compared to 10 d in 47 patien

关键词： Acute cholangitis Endoscopic biliary drainage Endoscopic retrograde cholangio-pancreatography Common bile duct stones Carcinoma gall bladder

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