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Effect of eccentric and inclined loading on the bearing capacity of strip footing placed on rock mass

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Journal of Mountain Science 2024年第1期21卷 292-312页

作者： Shuvankar DAS Debarghya chakraborty Department of Civil Engineering Indian Institute of Technology KharagpurWest Bengal-721302India

This paper deals with the bearing capacity determination of strip footing on a rock mass in hilly area by considering the influence of inclined and eccentric loading. Applying the generalized HoekBrown failure criterion, the failure behavior of the rock mass is modeled with the help of the power cone programming in the lower bound finite element limit analysis framework. Using bearing capacity factor(Ns), the change in bearing capacity of the strip footing due to the occurrence of eccentrically inclined loading is presented. The variations of the magnitude of Ns are obtained by examining the effects of the Hoek-Brown rock mass strength parameters(uniaxial compressive strength(sci), disturbance factor(D), rock parameter(mi), and Geological Strength Index(GSI)) in the presence of different magnitudes of eccentricity(e) and inclination angle(λ) with respect to the vertical plane, and presented as design charts. Both the inclined loading modes, i.e., inclination towards the center of strip footing(+λ) and inclination away from the center of strip footing(-λ), are adopted to perform the investigation. In addition, the correlation between the input parameters and the corresponding output is developed by utilizing the artificial neural network(ANN). Additionally, from sensitivity analysis, it is observed that inclination angle(λ) is the most sensitive parameter. For practicing engineers, the obtained design equation and design charts can be beneficial to understand the bearing capacity variation in the existence of eccentrically inclined loading in mountain areas.

关键词： Eccentric and inclined Power cone programming Rock mass Limit analysis Artificial neural network

Angiotensin-converting enzyme inhibitors from plants: A review of their diversity, modes of action, prospects, and concerns in the management of diabetes-centric complications

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Journal of Integrative Medicine 2021年第6期19卷 478-492页

作者： Rakhi chakraborty Swarnendu Roy Department of Botany A.P.C.Roy Government CollegeMatigara 734010West BengalIndia Plant Biochemistry Laboratory Department of BotanyUniversity of North BengalRaja Rammohunpur 734011West BengalIndia

Angiotensin-converting enzyme(ACE)inhibitors are antihypertensive medications often used in the treatment of diabetes-related *** ACE inhibitors are known to cause serious side effects like hypotension,renal insufficiency,and ***,there has been an intensifying search for natural ACE *** plants or plant-based extracts are known to possess ACEinhibitory *** this review,articles focusing on the natural ACE inhibitors extracted from plants were retrieved from databases like Google Scholar,Pub Med,Scopus,and Web of *** have found more than 50 plant species with ACE-inhibitory *** them,Angelica keiskei,Momordica charantia,Muntingia calabura,Prunus domestica,and Peperomia pellucida were the most potent,showing comparatively lower half-maximal inhibitory concentration *** the bioactive metabolites,peptides(e.g.,Tyr-Glu-Pro,Met-Arg-Trp,and Gln-Phe-Tyr-Ala-Val),phenolics(e.g.,cyanidin-3-Osambubioside and delphinidin-3-O-sambubioside),flavonoids([-]-epicatechin,astilbin,and eupatorin),terpenoids(ursolic acid and oleanolic acid)and alkaloids(berberine and harmaline)isolated from several plant and fungus species were found to possess significant ACE-inhibitory *** were also known to possess promising antioxidant,antidiabetic,antihyperlipidemic and anti-inflammatory *** the minimal side effects and lower toxicity of herbal compounds,development of antihypertensive drugs from these plant extracts or phytocompounds for the treatment of diabetesassociated complications is an important *** review,therefore,focuses on the ACE inhibitors extracted from different plant sources,their possible mechanisms of action,present status,and any safety concerns.

关键词： Angiotensin-converting enzyme Inhibitor Herbal medicine Hyperglycaemia Hypertension Bioactive metabolite

Oldest Asian Record of Snapping Shrimps(Malacostraca:Alpheidae)from the Kutch Basin,Western India and Associated Biota:Biostratigraphic,Paleoenvironmental and Paleoecological Significance

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Acta Geologica Sinica(English Edition) 2022年第6期96卷 1867-1883页

作者： Vivesh V.KAPUR Kamlesh KUMAR Pranav J.PANDYA amit KGHOSH Arindam chakraborty Anupam SHARMA Gaurav CHAUHAN M.G.THAKKAR Birbal Sahni Institute of Palaeosciences 53University RoadLucknow 226007India Department of Biology Shri R.R.Lalan CollegeBhujKachchh DistrictGujaratIndia Institute of Earth Sciences Academia SinicaTaipeiTaiwan 11529China Department of Earth and Environmental Science K.S.K.V.Kachchh UniversityBhujKachchh DistrictGujaratIndia

The oldest Asian record of alpheid shrimps,assigned to genus Alpheus,based on snapping claw fingertips from the Miocene Khari Nadi Formation in the Kutch Basin,western India reported herein,extends the fossil record of the family Alpheidae from Asia by~22 million *** early Miocene(Aquitanian)age is estimated based on the associated assemblage of calcareous nannofossils,Sphenolithus disbelemnos,Cyclicargolithus floridanus,and Reticulofenestra *** co-occurring microbiota includes bony fish otolith remains,identified as“genus Gobiidarum”,isolated teeth of Dasyatis rays,Sphyrna sharks,and teleosts,ctenoid and placoid scales,ostracods,belonging to the genera Paractinocythereis,Alocopocythere,Ruggieria,Aglaiocypris,Bairdoppilata,and echinoid *** together,the microfossil assemblage and data from chemical analyses using Energy Dispersive Spectroscopy,X-Ray Diffraction and Wavelength Dispersive X-Ray Fluorescence of host and associated lithologies suggests prevalence of a shallow(neritic)to coastal marine(intertidal)depositional *** present investigation also provides the oldest fossil evidence on the co-occurrence of Alpheus and gobiids(based on otoliths)that strongly advocates that the mutualistic association between these animal groups had developed by the Aquitanian.

关键词： biostratigraphy Crustacea Caridea Elasmobranchs Gobiidae invertebrate and vertebrate paleontology nannofossils Oligocene-Miocene Indian subcontinent

Transfer Matrix Approach for Two-State Scattering Problem with Arbitrary Coupling

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Chinese Physics Letters 2015年第7期32卷 5-8页

作者： Diwaker Aniruddha chakraborty School of Basic Sciences Indian Institute of Technology Mandi

The present work deals with the calculation of transition probability between two diabatic potentials coupled by any arbitrary coupling. The method presented in this work is applicable to any type of coupling while for numerical calculations we have assumed the arbitrary coupling as Gaussian coupling. This arbitrary coupling is expressed as a collection of Dirac delta functions and by the use of the transfer matrix technique the transition probability from one diabatic potential to another diabatic potential is calculated. We examine our approach by considering the case of two constant potentials coupled by Gaussian coupling as an arbitrary coupling.

关键词： Transfer Matrix Approach for Two-State Scattering Problem with Arbitrary Coupling

Syn-sedimentary tectonics and facies analysis in a rift setting: Cretaceous Dalmiapuram Formation, Cauvery Basin, SE India

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Journal of Palaeogeography 2018年第2期7卷 146-167页

作者： Nivedita chakraborty Subir Sarkar Department of Geology Kabi Jagadram Roy Govt. General Degree College Department of Geological Sciences Jadavpur University

The Cretaceous(Albian-Cenomanian) Dalmiapuram Formation is one of the economically significant constituents in the hydrocarbon-producing Cauvery rift basin, SE India that opened up during the Late Jurassic e Early Cretaceous Gondwanaland fragmentation. The fossil-rich Dalmiapuram Formation,exposed at Ariyalur within the Pondicherry sub-basin of Cauvery Basin, rests in most places directly on the Archean basement and locally on the Lower Cretaceous(Barremian-Aptian) Basal Siliciclastic Formation. In the Dalmiapuram Formation, a facies association of tectonically-disturbed phase is sandwiched between two drastically quieter phases. The early syn-rift facies association(FA 1), records the first carbonate marine transgression within the basin, comprising a bar-lagoon system with occasionally storms affecting along the shore and a sheet-like non-recurrent biomicritic limestone bed on the shallow shelf that laterally grades into pyrite e glauconite-bearing dark-colored shale in the deeper shelf. Spectacular breccias together with varied kinds of mass-flow products comprise the syn-rift facies association(FA 2). While the breccias occur at the basin margin area, the latter extend in the deeper inland sea. Clast composition of the coarse clastics includes large, even block-sized limestone fragments and small fragments of granite and sandstone from the *** beds of quieter intervals between tectonic pulses occur in alternation with them. Faulted basal contact of the formation, and small grabens filled by multiple mass-flow packages bear the clear signature of the syntectonic activity localized contortions, slump folds, and pillow beds associated with mega slump/slide planes and joints, which corroborates this contention further. This phase of tectonic intervention is followed by another relatively quieter phase and accommodates the late syn-rift facies association(FA 3). A tidal bar-interbar shelf depositional system allowed a transgressive systems tract motif to gr

关键词： Syn-sedimentary tectonics Facies analysis Carbonate shelf Cretaceous Dalmiapuram Formation Cauvery Basin

Phenolic Profile,Antioxidant,Antihyperlipidemic and Cardiac Risk Preventive Effect of Pigmented Black Rice Variety Chakhao poireiton in High-Fat High-Sugar Induced Rats

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Rice science 2023年第6期30卷 641-651页

作者： Raja chakraborty Pratap KALITA Saikat SEN Faculty of Pharmaceutical Science Assam down town UniversityAssam 781026India Institute of Pharmacy Assam Don Bosco UniversityAssam 782402India Pratiksha Institute of Pharmaceutical Sciences GuwahatiAssam 781026India

The present study aimed to investigate the hypolipidemic,antioxidant and cardiac risk-suppressing effects of Chakhao poireiton(CP),a GI-tagged pigmented black rice from *** vitro and ex vivo studies confirmed that whole rice extracts of CP have potent antioxidant,3-hydroxy-3-methylglutaryl-CoA reductase,cholesterol esterase inhibitory,and antilipase *** in vivo study was conducted to evaluate the effects of the ethanol extracts of CP on high-fat high-sugar induced hyperlipidemic *** ethanol extract significantly ameliorated lipid parameters and liver enzymes to *** of lactate dehydrogenase,creatine kinase-N-acetyl cysteine,C-reactive protein,and lipoprotein a were significantly lower in the extract-treated groups than those in the disease control group.A marked reduction of ApoB/ApoA1 and other atherogenic indices were observed in extract-treated *** phenolic compounds,*** acid,gallic acid,protocatechuic acid etc.,were quantified in *** study provided the first evidence of the antihyperlipidemic and cardiac risk inhibitory effects of CP,which would be beneficial in preventing and managing hyperlipidemia,associated oxidative stress,and cardiac complications.

关键词： antioxidant cardiac risk high fat high sugar hypolipidemic phenolic compound pigmented rice whole rice

Using Statistical Modeling,Rate of Change of Pitch and Inter-Onset Interval to Distinguish Between Restful and Restless Ragas

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Communications in Mathematics and Statistics 2017年第2期5卷 199-212页

作者： Poonam Priyadarshini Soubhik chakraborty Department of Electronics and Communication Engineering Birla Institute of TechnologyPatna CampusPatnaIndia Department of Mathematics Birla Institute of TechnologyMesraRanchiIndia

Given that the strength of statistics lies in modelling,we are motivated to do a comparative statistical study between two types of ragas,one being aesthetically known to be restful and the other restless in *** first try to distinguish these two types through statistical *** substantiate our findings,two more sta-tistical features are considered in the paper to separate the two categories of ragas,namely the rate of change of pitch and inter-onset *** experimental results are encouraging.

关键词： Raga {Restful,restless}nature Rate of pitch change Inter Onset interval Statistical modeling

Enzyme hydrolyzed bael fruit liquefaction and its kinetic study

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Food Bioscience 2022年第3期47卷 1189-1201页

作者： Rishab Dhar Snehasis chakraborty Food Engineering and Technology Department Institute of Chemical TechnologyMumbaiMatunga (E)Maharashtra400019India

The study aims to explore the mechanism and optimize the process of enzyme hydrolyzed bael fruit(Aegle marmelos)liquefaction using two different enzymes:pectinase and macerozyme r-10(enzyme mixture).A full factorial design was applied for the factors with 0.05–1.5%(w/w)enzyme concentration(EC),30–60℃ temperature,and incubation time of 30–240 min for pectinase and 60–360 min for *** polynomial models were developed,showing R^(2)≥***-objective numeric optimization was followed to maximize the increase in yield,total reducing sugar(TRS),clarity,and minimizing EC,temperature and ***-treated juice extracts were acceptable on the sensory scale with overall acceptability>*** pomace reduction of 58.8%and 78.9%along with rise in mono and disaccharides were observed after treating with pectinase(t=240 min)and macerozyme(t=360 min),respectively at identical 0.775%EC and 45℃ *** the pectinase enzyme,an optimumΔyield of 32.4%was obtained at 0.82%EC,43℃ temperature in 169.4 ***,with the macerozyme,an optimumΔyield of 39.6%was attained at 0.96%EC,45.6°C temperature in 245.9 *** degradation in bael fruit by enzymatic hydrolysis with pectinase(EC=0.01–1.50%,time=2.5–240 min)and macerozyme(EC:0.01–1.50%,time:5–360 min)was studied at their respective optimum *** modified Michaelis-Menten showed a good fit(R 2>0.98)with the non-linear curve fitting *** treatment showed slower enzyme activity with higher substrate degradation but lower nutrient content compared to the pectinase treatment.

关键词： Bael fruit Enzyme hydrolysis Full factorial design Sensory evaluation Optimization Kinetic modeling

Rhinofacial conidiobolomycosis in an immunocompetent 30-year-old male:A case report

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Asian Pacific Journal of Tropical Medicine 2023年第7期16卷 329-331,I0001页

作者： Sourav Kundu Sambudhya chakraborty Department of Tropical Medicine School of Tropical MedicineKolkataWest BengalIndia

Rationale:Fungal rhinosinusitis is a rare entity in immunocompetent patients and is a diagnostic *** is a rare cause of fungal rhinosinusitis which happens to affect immunocompetent *** concerns:A 30-year-old male patient complained of painless progressive swelling of nose for 5 years and painless progressive swelling of upper lip for 4 years associated with nasal obstruction for 5 ***:Rhinofacial ***:Systemic anti-fungals and saturated solution of potassium ***:Swelling initially reduced but again increased eventually as he discontinued ***:Proper adherence to drugs and need for facial reconstructive surgery may need to be considered in such cases of conidiobolomycosis.

关键词： Conidiobolomycosis Fungus Rhinosinusitis Tropical Rhino facial Entomophthoramycosis