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Hospital bed capacity across in Tunisia hospital during the first 4 waves of the COVID-19 pandemic:A descriptive analysis

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Infectious Medicine 2023年第2期2卷 112-121页

作者： Slimane BenMiled Chiraz Borgi Mohamed Hsairi Naoufel Somrani amira Kebir Bio-(Informatic Mathematics and Statistic)BIMS-Lab LR09-IPT16Institut Pasteur de TunisUniversity of Tunis el ManarTunis 1002Tunisia Ministry of Health Tunis 1002Tunisia Department of Epidemiology and Preventive Medicine Faculty of MedecinTunis El Manar UniversityTunis 1002Tunisia IPEIT University of TunisTunis 1002Tunisia

Background:In March 2020,the WHO declared COVID-19 as a pandemic,and Tunisia implemented a containment and targeted screening *** country’s public health policy has since focused on managing hospital ***:The study analyzed the bed occupancy rates in public hospitals in Tunisia during the *** evolution of daily cases and nonpharmaceutical interventions(NPI)actions undertaken by the Tunisian Government were also *** study used 3 indices to assess bed flexibility:Ramp duration until the peak,ramp growth until the peak,and ramp rate until the *** study also calculated the time shift at the start and peak of each wave to evaluate the government’s response ***:The study found that the evolution of the epidemic in Tunisia had 2 *** first phase saw the pandemic being controlled due to strong NPI actions,while the second phase saw a relaxation of measures and an increase in wave *** bed availability followed the demand for beds,but ICU bed occupancy remained high,with a maximum of 97%.The government’s response in terms of bed distribution and reallocation was *** study found that the most deadly wave by ICU occupied bed was the third wave due to a historical variant,while the fifth wave due to the delta variant was the most deadly in terms of cumulative ***:The study concluded that decision-makers could use its findings to assess their response capabilities in the current pandemic and future *** study highlighted the importance of flexible and responsive healthcare systems in managing pandemics.

关键词： Bed occupancy Daily cases Daily death Ramp duration until the peak(RDUP) Ramp growth until the peak(RGUP) Ramp rate until the peak(RRUP)

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Exendin-4 inhibits the survival and invasiveness of two colorectal cancer cell lines via suppressing GS3Kβ/β-catenin/NF-κB axis through activating SIRT1

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BIOCELL 2021年第5期45卷 1337-1353页

作者： ATTALLA F.EL-KOTT AYMAN E.EL-KENAWY EMAN R.ELBEALY ali S.ALSHEHRI HEBA S.KHaliFA MASHAEL MOHAMMED BIN-MEFERIJ EHAB E.MASSOUD amira M.ALRAMLAWY Biology Department College of ScienceKing Khalid UniversityAbha61413Saudi Arabia Zoology Department College of ScienceDamanhour UniversityDamanhour22511Egypt Pathology Department College of MedicineTaif UniversityTaif11099Saudi Arabia Biology Department College of Science for GirlsKing Khalid UniversityAbha61413Saudi Arabia Biology Department College of SciencePrincess Nourah Bint Abdulrahman UniversityRiyadh84428Saudi Arabia Biology Department Faculty of Science and ArtsDahran AljnoubKing Khalid UniversityAbha61413Saudi Arabia Research Center for Advanced Materials Science King Khalid UniversityAbha61413Saudi Arabia Agriculture Research Centre SoilWater and Environment Research InstituteGiza12619Egypt Mansoura Research Centre for Cord Stem Cell(MARC-CSC) Stem Cells BankChildren’s HospitalMansoura UniversityMansoura35516Egypt

This study examined if the anti-tumorigenesis effect of Exendin-4 in HT29 and HCT116 colorectal cancer(CRC)involves modulation of SIRT1 and Akt/GSR3K/β-catenin/NF-κB ***29 and HCT116 cells were treated either with increasing levels of Exendin-4(0.0-200μM)or with Exendin-4(at its IC50)in the presence or absence of EX-527(10μM/a selective SIRT1 inhibitor)or Exendin-4(9-39)amide(E(9-39)A)(1μM/an Exendin-4 antagonist).In a dose-dependent manner,Exendin-4 inhibited cell survival,but enhanced levels of lactate dehydrogenase(LDH)and single-stranded DNA(ssDNA)in both HT29 and *** both cell lines and at it has an IC50(45μM for HT29 and 35μM for HCT1165),Exendin-4 also significantly reduced cell survival,migration,and invasion of both cell types,with no effect on the expression GLP-1 receptors(GLPRs)nor of the activity of *** these doses,Exendin-4 also increased the expression of SIRT1 but reduced the acetylation of NF-κB and the expression of Bax and cleaved caspase-3 and in both cell ***,protein levels of p-GS3Kβ(Ser9),total and acetylatedβ-catenin,and Anix2 were significantly decreased,but levels of p-GS3Kβ(Ser9)and p-β-catenin(Ser33/37/Thr41)were significantly increased in both HT29 and HCT116-exendin-4 treated *** the effects exerted by Exendin-4 were completely prevented by Ex527 or E(9-39)*** conclusion,Exendin-4 suppresses the tumorigenesis of HT29 and HCT116 CRC cell activation of GS3Kβ-induced inhibition ofβ-catenin and NF-κβin a SIRT1-dependent mechanism.

关键词： Colorectal cancer Exendin-4 SIRT1 GS3Kβ β-catenin NF-κB

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Efficacy of Gold Nanoparticles against Nephrotoxicity Induced by Schistosoma mansoni Infection in Mice

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Biomedical and Environmental Sciences 2016年第11期29卷 773-781页

作者： Mohamed A Dkhil Mona F Khalil2 amira A Bauom Marwa SM Dia Saleh A1-Qura Department of Zoology College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia Department of Zoology and Entomology Faculty of ScienceHelwan UniversityCairo 11795Egypt Department of Laboratory Sciences College of Science&ArtsA1-RassQassim UniversityAL-Qaseam 51921Saudi Arabia Molecular Drug Evaluation Department National Organization for Drug Control&Research(NODCAR)Giza 12553Egypt

Objective In this study, the ameliorative effects of gold nanoparticles （gold NP） on the renal tissue damage in Schistosoma mansoni （S. mansoni）-infected mice was investigated. Methods High-resolution transmission electron microscopy was used for the characterization of NP. The gold NP at concentrations of 250, 500, and 1000 μg/kg body weight were inoculated into 5. mansoni-infected mice. Results The parasite caused alterations in the histological architecture. Furthermore, it induced a significant reduction in the renal glutathione levels; however, the levels of nitric oxide and malondialdehyde were significantly elevated. The parasite also managed to downregulate KIM-I, NGAL, MCP-1, and TGF-8 mRNA expression in infected animals. Notably, gold NP treatment in mice reduced the extent of histological impairment and renal oxidative damage. Gold NP were able to regulate gene expression impaired by 5. Mansoni infection. Conclusion The curative effect of gold NP against renal toxicity in 5. mansoni-infected mice is associated with their role as free radical scavengers.

关键词： Gold nanoparticles Schistosomiasis Renal damage Gene expression Histopathology Oxidative stress

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Chitosan/Nanocrystalline Cellulose Biocomposites Based on Date Palm (Phoenix Dactylifera L.) Sheath Fibers

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Journal of Renewable Materials 2019年第6期7卷 567-582页

作者： Abeer M.Adel amira M.El-Shafei Atef A.Ibrahim Mona T.Al-Shemy Cellulose and Paper Department National Research Center33El-Bohouth St.(Former El-Tahrir St.)DokkiP.O.12622GizaEgypt Textile Research Division National Research Center33El-Bohouth St.(Former El-Tahrir St.)DokkiP.O.12622GizaEgypt

In this study,nanocrystalline celluloses were used to enhance physical,mechanical and water vapor barrier properties of chitosan films for potential food packaging *** different mineral acids(sulfuric and phosphoric)were used to extract nanocrystalline cellulose from date palm sheath *** influence of cellulose I and cellulose II on the properties of the isolated nanocrystalline celluloses(e.g.,yield,energy and length of intra-and intermolecular hydrogen bonds,and degree of substitution)were studied *** characteristics of chitosan biocomposite film with phosphorylated nanocrystalline cellulose were compared to those with sulfated nanocrystalline *** showed that besides cellulose polymorphism,the ionic ester groups on the surface of nanocrystalline cellulose is one of the factors influencing the physical,chemical,mechanical,and water vapor barrier properties in chitosan/nanocrystalline cellulose biocomposites.

关键词： Biocomposite Cellulose I Cellulose II Nanocrystalline cellulose(NCC) physico-mechanical properties Thermal stability

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Freedom of Speech and Newspaper Excesses

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Sociology Study 2014年第8期4卷 681-690页

作者： amira Massaabi University of Umm Kuraa Kingdom of Saudi Arabia

Press has been found to have an impact on the outcome of electoral political campaigns. Press can distort the electorate＇s perception of an objective reality to fulfill the political orientation of its editorial line. This can be achieved in propaganda and in the rhetoric of excess. Within the framework of Critical Discourse Analysis （CDA）, this paper has conducted a thematic content analysis to study the rhetoric of excess in the construction of political identity and relations in 100 articles pertaining to two different ideologically oriented Tunisian newspapers, namely Le Maghreb and El Dhamir. The study covered the period from December 26, 2011 to December 26, 2012. Results have shown a low level of impartiality violating Gricean maxims of quality and quantity. This tendency could culminate in violence and undermine the public＇s confidence in the media. Proactive measures of media management are recommended.

关键词： Critical Discourse Analysis (CDA) media freedom and ethics the rhetoric of excess political identity ideology

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Outcome of Nurses with Occupational Dermatitis

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Open Journal of Nursing（护理学期刊） 2024年第6期 239页

作者： amira Omrane Chayma Harrathi Asma Kheder Maher Maoua Malek Ben Abdelkader Taoufik Khalfallah Najib Mrizak Mohamed Akrout Mohamed Adnene Henchi Hichem Bel Hadj ali

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Studying of Common Factors Affecting Reading of Lithium Fluoride Thermo-Luminescence Dosimeter Crystal

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Open Journal of Biophysics 2017年第1期7卷 14-24页

作者： Mohammed A. ali Omer Abdulrahman A. Alsayyari Jumaa Y. Tamboul Rowida B. ali amira A. Ahmed Ahmed Abukonna Department of Radiologic Technology College of Applied Medical Science Qassim University Buraidah KSA Department of Radiotherapy College of Medical Radiologic Science Sudan University of Science & Technology Khartoum Sudan Department of Diagnostic Radiologic Technology College of Applied Medical Sciences Taibah University Medina KSA Department of Radiation Safeties Sudan Atomic Energy Commission Khartoum Sudan

The aim of this study was to study the technical factors affecting the reading of TLD (LiF:Mg:Ti) for radiation dosimetry. The method adapted was an exposure of LiF:Mg:Ti crystal with?γ-ray with the following filters (Hp 0.07 and Hp?10), before and after usage of filter Hp?(0.07), annealing, cooling by nitrogen flux and crystal morphology by scanning electron microscope. The collected data analyzed by EXCELL software showed that: TLD average count/second (C/s) with filter Hp?(10) was greater than that obtained with filter Hp?(0.07) with an amount of 1191 c/s?(19%). Also the analysis showed that: the average C/s without filter Hp?(0.07) was greater than that with filter by an amount of 994.5 C/s (16.4%), and there was proportional linear relationship;as the applied dose increased the TLD C/s increased significantly (R2?=?0.9) based on the equations: y = 885.1x???286.5 and y = 860.5x?+ 856.8 for filtered and without filtered beam respectively, where?x?refers to applied dose in mGy and?y?refers to C/s. Also the average C/s without nitrogen flux (cooling) was greater than with nitrogen count with an amount of 52.4 C/s (11%). The annealing (without filter) causes a reduction in dose by 82.2?μGy (19.2%), and in case of annealing with filter, the dose reduced by 66.7?μGy (21.9%) relative to annealing without filter. The morphology of TLD crystal shown by scanning electron microscope SEM was a darkening surface after irradiation.

关键词： Radiation Effects Dosimeter Factors Thermoluminescence

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Intelligent Aquila Optimization Algorithm-Based Node Localization Scheme for Wireless Sensor Networks

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Computers, Materials & Continua 2023年第1期74卷 141-152页

作者： Nidhi Agarwal M.Gokilavani S.Nagarajan S.Saranya Hadeel Alsolai Sami Dhahbi amira Sayed Abdelaziz Department of Information Technology KIET Group of InstitutionsDelhi201206India Department of Computer Science and Engineering Indira Gandhi Delhi Technical University for WomenNew DelhiDelhi110006India Department of Computer Science and Engineering KL UniversityVaddeswaramAndhra Pradesh522502India Department of Electronics&Communication Engineering Saveetha Engineering CollegeChennai602105India Department of Computer Science and Engineering K.Ramakrishnan College of EngineeringTiruchirapalli621112India Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Computer Science College of Science&Art at MahayilKing Khalid UniversityMuhayel Aseer62529Saudi Arabia Department of Digital Media Faculty of Computers and Information TechnologyFuture University in EgyptNew Cairo11835Egypt

In recent times,wireless sensor network(WSN)finds their suitability in several application areas,ranging from military to commercial *** nodes in WSN are placed arbitrarily in the target field,node localization(NL)becomes essential where the positioning of the nodes can be determined by the aid of anchor *** goal of any NL scheme is to improve the localization accuracy and reduce the localization error *** this motivation,this study focuses on the design of Intelligent Aquila Optimization Algorithm Based Node Localization Scheme(IAOAB-NLS)for *** presented IAOAB-NLS model makes use of anchor nodes to determine proper positioning of the *** addition,the IAOAB-NLS model is stimulated by the behaviour of *** IAOAB-NLS model has the ability to accomplish proper coordinate points of the nodes in the *** guaranteeing the proficient NL process of the IAOAB-NLS model,widespread experimentation takes place to assure the betterment of the IAOAB-NLS *** resultant values reported the effectual outcome of the IAOAB-NLS model irrespective of changing parameters in the network.

关键词： Aquila optimizer node localization WSN intelligent models unknown nodes anchor nodes

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Human Gait Recognition:A Deep Learning and Best Feature Selection Framework

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Computers, Materials & Continua 2022年第1期70卷 343-360页

作者： Asif Mehmood Muhammad Attique Khan Usman Tariq Chang-Won Jeong Yunyoung Nam Reham R.Mostafa amira ElZeiny Department of Computer Science COMSATS University IslamabadWah Campus47080Pakistan Department of Computer Science HITEC University TaxilaTaxila47040Pakistan College of Computer Engineering and Sciences Prince Sattam Bin Abdulaziz UniversityAl-KhrajSaudi Arabia Medical Convergence Research Center Wonkwang UniversityIksanKorea Department of Computer Science and Engineering Soonchunhyang UniversityAsanKorea Department of Information Systems Faculty of Computers and Information SciencesMansoura UniversityMansoura35516Egypt Department of Information Systems Faculty of Computers and InformationDamietta UniversityDamiettaEgypt

Background—Human Gait Recognition(HGR)is an approach based on biometric and is being widely used for *** is adopted by researchers for the past several *** factors are there that affect the system performance such as the walking variation due to clothes,a person carrying some luggage,variations in the view ***—In this work,a new method is introduced to overcome different problems of HGR.A hybrid method is proposed or efficient HGR using deep learning and selection of best *** major steps are involved in this work-preprocessing of the video frames,manipulation of the pre-trained CNN model VGG-16 for the computation of the features,removing redundant features extracted from the CNN model,and *** the reduction of irrelevant features Principal Score and Kurtosis based approach is proposed named *** that,the features of PSbK are fused in one ***,this fused vector is fed to the One against All Multi Support Vector Machine(OAMSVM)classifier for the final ***—The system is evaluated by utilizing the CASIA B database and six angles 00◦,18◦,36◦,54◦,72◦,and 90◦are used and attained the accuracy of 95.80%,96.0%,95.90%,96.20%,95.60%,and 95.50%,***—The comparison with recent methods show the proposed method work better.

关键词： Human gait recognition deep features extraction features fusion features selection

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Aphrodisiac potential of Polyalthia bullata (Tongkat ali) in fowl

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Asian pacific Journal of Reproduction 2021年第2期10卷 75-81页

作者： Jaya Vejayan Yasmin amira Che Yahya Srikumar Chakravarthi Halijah Ibrahim Aida Yun Faculty of Industrial Sciences&Technology Universiti Malaysia PahangLebuhraya Tun Razak26300GambangKuantanPahang Darul MakmurMalaysia Faculty of Medicine Biomedical Sciences and NursingMAHSA UniversityJalan SP2Bandar Saujana Putra42610 Jenjarom SelangorMalaysia Institute of Biological Sciences University of Malaya50603 Kuala LumpurMalaysia Ubat Tradisional Orang Asli Dataran Sungai Perak Sebelah UtaraNorth-South ExpresswayKampung Menora33000 Kuala KangsarPerak Darul RidzuanMalaysia

Objective:To study the aphrodisiac potential of Polyalthia(P.)bullata in ***:In this study,testosterone,as an indicator of the aphrodisiac potential of ***,was investigated for its release from TM3 Leydig cells grown in vitro and in 4 fowls given capsules containing *** at a dose of 10 mg in each capsule twice a day,for 50 *** the latter in vivo evaluation,mating behaviours were additionally determined after the treated fowls were released to the individual hens,and their testes and liver were dissected for histological *** drawn from the fowls was assessed for any changes in diagnostic ***:In the in vitro test(TM3 Leydig cells),*** was able to increase testosterone to 0.48 nmol/L within 72 h of incubation,compared to the untreated control with only 0.18 nmol/L,i.e.,an increase of 170%.In the in vivo test,outcomes in the fowls dosed with *** showed similar positive elevations of testosterone to(9.72±1.10)nmol/L in comparison to the controls that showed a level of only(4.05±0.84)nmol/*** frequencies of mating behaviours were observed(wing flapping,body shakes,crowing and beak pecking)to be 23 counts for the test compared to only 15 for the control *** examination of the male reproductive organs provided evidence of testosterone boosting based on an observable increase in the activity at the seminiferous tubules of testis tissues without any damaging effects,compared to the *** the nine diagnostic blood parameters assessed,including alanine aminotransferase,aspartate aminotransferase,and gamma glutamyltransferase,none was remarkably elevated compared to the *** histological changes in the liver were not severe and mainly consisted of only localized moderate but recoverable obstructions and swellings of the vessels and ***:*** is able to boost testosterone both in vitro and in vivo,with no acute toxicities.

关键词： Male hormone Testosterone Steroids Leydig cells Domestic chicken Cock Medicinal plant Polyalthia bullata

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