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Invasive candidiasis in critical care setting, updated recommendations from “Invasive Fungal Infections-Clinical Forum”, Iran

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World Journal of Critical Care Medicine 2014年第4期3卷 102-112页

作者： Ashraf Elhoufi Arezoo Ahmadi amir Mohammad Hashem Asnaashari Mohammad ali Davarpanah Behrooz Farzanegan Bidgoli Omid Moradi Moghaddam Mohammad Torabi-Nami Saeed Abbasi Malak El-Sobky ali Ghaziani Mohammad Hossein Jarrahzadeh Reza Shahrami Farzad Shirazian Farhad Soltani Homeira Yazdinejad Farid Zand Department of Critical Care Medicine Dubai Hospital Dubai Health Authority Department of Anesthesiology and Critical Care Sina Hospital Tehran University of Medical Sciences Department of Pulmonology and Critical Care Ghaem Hospital Mashhad University of Medical Sciences Department of Infectious Diseases and Tropical Medicine Shiraz University of Medical Sciences Tracheal Disease Research Center Shahid Behesti University of Medical Sciences Department of Anesthesiology and Critical Care Rasoul-e-Akram Hospital Iran University of Medical Sciences Department of Neuroscience School of Advanced Medical Sciences and Technologies Shiraz University of Medical Sciences Behphar Scientific Committee Behphar Group Anesthesiology and Critical Care Research Center Isfahan University of Medical Sciences Invasive Fungal Infections-Clinical Forum Intensive Care and Burn Units Motahhari Hospital Intensive Care Unit Vali-e-Asr Hospital NAJA University Department of Anesthesiology and Critical Care Golestan Hospital Ahwaz Jundishapur University of Medical Sciences Department of Anesthesiology and Critical Care Taleghani Hospital Shahid Beheshti University of Medical Sciences Shiraz Anesthesiology and Critical Care Research Center Shiraz University of Medical Sciences

Invasive candidiasis(IC) bears a high risk of morbidity and mortality in the intensive care units(ICU). With the current advances in critical care and the use of widespectrum antibiotics, invasive fungal infections(IFIs) and IC in particular, have turned into a growing concern in the ICU. Further to blood cultures, some auxil-iary laboratory tests and biomarkers are developed to enable an earlier detection of infection, however these test are neither consistently available nor validated in our setting. On the other hand, patients' clinical status and local epidemiology data may justify the empiric antifungal approach using the proper antifungal option. The clinical approach to the management of IC in febrile, non-neutropenic critically ill patients has been defined in available international guidelines; nevertheless such recommendations need to be customized when applied to our local practice. Over the past three years, Iranian experts from intensive care and infectious diseases disciplines have tried to draw a consensus on the management of IFI with a particular focus on IC in the ICU. The established IFI-clinical forum(IFI-CF), comprising the scientific leaders in the field, has recently come up with and updated recommendation on the same(June 2014). The purpose of this review is to put together literature insights and Iranian experts' opinion at the IFI-CF, to propose an updated practical overview on recommended approaches for the management of IC in the ICU.

关键词： Invasive candidiasis Intensive care unit IFI-clinical forum Recommendations Iran

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The Digital Agricultural Knowledge and Information System(DAKIS):Employing digitalisation to encourage diversified and multifunctional agricultural systems

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Environmental Science and Ecotechnology 2023年第4期16卷 177-189页

作者： Ioanna Mouratiadou Nahleen Lemke Cheng Chen Ariani Wartenberg Ralf Bloch Marco Donat Thomas Gaiser Deepak Hanike Basavegowda Katharina Helming Seyed ali Hosseini Yekani Marcos Krull Kai Lingemann Joseph Macpherson Marvin Melzer Claas Nendel Annette Piorr Mostafa Shaaban Peter Zander Cornelia Weltzien Sonoko Dorothea Bellingrath-Kimura Leibniz Centre for Agricultural Landscape Research(ZALF) Eberswalder Straße 8415374MünchebergGermany ISARA Laboratory of Rural Studies Research UnitLyon23 Rue Jean Baldassini69364Lyon Cedex 07France Faculty of Landscape Management and Nature Conservation University for Sustainable Development(HNEE)Schickler Straße 516225EberswaldeGermany Institute of Crop Science and Resource Conservation University of Bonn53115BonnGermany Leibniz Institute for Agricultural Engineering and Bioeconomy(ATB) Max-Eyth-Allee 10014469PotsdamGermany German Research Center for Artificial Intelligence(DFKI) Trippstadter Strasse 12267663KaiserslauternGermany Institute of Biochemistry and Biology University of PotsdamAm Mühlenberg 314476Potsdam(Golm)Germany Global Change Research Institute The Czech Academy of ScienceBělidla 986/4a60300BrnoCzech Republic

Multifunctional and diversified agriculture can address diverging pressures and demands by simultaneously enhancing productivity,biodiversity,and the provision of ecosystem *** use of digital technologies can support this by designing and managing resource-efficient and context-specific agricultural *** present the Digital Agricultural Knowledge and Information System(DAKIS)to demonstrate an approach that employs digital technologies to enable decision-making towards diversified and sustainable *** develop the DAKIS,we specified,together with stakeholders,requirements for a knowledge-based decision-support tool and reviewed the literature to identify limitations in the current generation of *** results of the review point towards recurring challenges regarding the consideration of ecosystem services and biodiversity,the capacity to foster communication and cooperation between farmers and other actors,and the ability to link multiple spatiotemporal scales and sustainability *** overcome these challenges,the DAKIS provides a digital platform to support farmers'decision-making on land use and management via an integrative spatiotemporally explicit approach that analyses a wide range of data from various *** approach integrates remote and in situ sensors,artificial intelligence,modelling,stakeholder-stated demand for biodiversity and ecosystem services,and participatory sustainability impact assessment to address the diverse drivers affecting agricultural land use and management design,including natural and agronomic factors,economic and policy considerations,and socio-cultural preferences and ***,the DAKIS embeds the consideration of ecosystem services,biodiversity,and sustainability into farmers'decision-making and enables learning and progress towards site-adapted small-scale multifunctional and diversified agriculture while simultaneously supporting farmers'objectives and societal demands.

关键词： Digital agriculture Ecosystem services Decision support system Farming practices Biodiversity Modelling Small-scale management

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早期床旁运动干预在心脏手术后患者心脏康复中的应用效果

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中国临床医学 2022年第4期29卷 621-626页

作者： M.Rafi HAMIDI 陈轶洪弥守玲陆云涛丛硕王文硕 Hosna HAMIDI 杨晔 M.Salim BAHRAMAND ali Ateel DAIFOLADI Babrak SAYEDZADA 刘欢魏来王春生复旦大学附属中山医院心血管外科上海心血管病研究所上海200032 世界卫生组织区域卫生组喀布尔1001阿富汗红新月会卫生部喀布尔1001阿富汗喀布尔amir Hajizada医院心血管外科喀布尔1001阿富汗法国母婴研究所心血管外科咯布尔1001阿富汗

目的评估早期床旁运动干预对心脏瓣膜手术后患者康复的影响。方法纳入40例心脏瓣膜疾病患者,其中20例患者[(49.05±3.728)岁]术后第3、4、5天接受床旁运动干预(3 min/d,干预组),其余20例患者[(47.95±3.214)岁]未接受床旁运动干预(对照... 详细信息

目的评估早期床旁运动干预对心脏瓣膜手术后患者康复的影响。方法纳入40例心脏瓣膜疾病患者,其中20例患者[(49.05±3.728)岁]术后第3、4、5天接受床旁运动干预(3 min/d,干预组),其余20例患者[(47.95±3.214)岁]未接受床旁运动干预(对照组)。术前进行心理教育,并通过标准化问卷简表对患者单独评估。通过指脉氧仪及6 min步行距离来评估心脏康复效果。结果干预组心脏瓣膜患者术后3 d的SpO_(2)水平高于对照组(P<0.05)。干预组术后5 d心率降至基线水平,低于对照组(P<0.05)。结论初级床旁运动(3 min/d)可以提高SpO_(2)、降低心率,进而改善患者基线状态,促进患者康复。

关键词：心脏康复成人心脏手术 6分钟步行测试床旁干预

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Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yan Yerevan Physics Institute YerevanArmenia UniversitéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Department of Physics National T

The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main *** of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator *** this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approximately 60,000 signal and 30,000 background events are *** large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith ***,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment.

关键词： neutrino oscillation solar neutrino JUNO

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