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Promising effect of Magliasa, a traditional Iranian formula, on experimental colitis on the basis of biochemical and cellular findings

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World Journal of Gastroenterology 2013年第12期19卷 1901-1911页

作者： Roja Rahimi amir Baghaei Maryam Baeeri Gholamreza Amin Mohammad Reza shams-Ardekani Mahnaz Khanavi Mohammad Abdollahi Department of Traditional Pharmacy Tehran University of Medical Sciences Pharmaceutical Sciences Research Center Tehran University of Medical Sciences Department of Pharmacology and Toxicology Tehran University of Medical Sciences Department of Pharmacognosy Tehran University of Medical Sciences

AIM: To investigate the efficacy of Magliasa, a traditional Iranian formula, on experimental colitis. METHODS: After botanical authentication of herbal ingredients, formulation of Magliasa, quantitative determination of total glucosinolates and total phenolic content, and analysis of the thin layer chromatography profile were performed. Colitis was then induced in male rats by instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in all groups, aside from the Sham *** experimental groups consisted of: the Sham group that received only normal saline; the Mag-50, Mag-100 and Mag-200 groups, which received 50, 100 and 200 mg/kg per day of Magliasa, respectively; the control group, which received vehicle water orally; the infliximab group, which received infliximab (5 mg/kg per day, subcutaneously); and the Dexa group, which received dexamethasone (1 mg/kg per day, orally). After completing the treatment period (2 wk), the rats were sacrificed, the colon was removed, its macroscopic and microscopic changes were recorded, and tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1b), total antioxidant capacity, myeloperoxidase (MPO), and lipid peroxidation (LPO) were assessed in colon ***: The mean value of total glucosinolates in one gram of Magliasa was 19 ± 1 μmol. The mean value of the total phenolic content was 293.8 ± 17.6 mg gallic acid equivalents per 100 gram of Magliasa. Macroscopic scores were significantly decreased in Mag-100 (1.80 ± 0.58, P = 0.019) and Mag-200 (1.20 ± 0.20, P = 0.001) compared to the control group (3.40 ± 0.24), although some inflammation and hyperemia were evident. Treatment of rats by dexamethasone (0.33 ± 0.21, P < 0.001) and infliximab (0.83 ± 0.31, P < 0.001) remarkably attenuated scores where mild hyperemia was observed macroscopically. In comparison to the control group (4.00 ± 0.32), only Mag-200 (1.60 ± 0.40) showed a significant decrease in colonic histopathological scores (P = 0.005). Minimal mucos

关键词： Magliasa Traditional Iranian medicine Colitis Neutrophil infiltration Inflammatory cytokines Oxidative stress

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Mental training can improve physical activity behavior in adolescent girls

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Journal of Sport and Health Science 2017年第3期6卷 327-332页

作者： Mahboubeh Ghayour Najafabadi amir-hossein Memari Ramin Kordi Monir Shayestehfar Mohammad-Ali Eshghi Department of Physical Education and Sport Sciences University of TehranTehran ***Iran Sports Medicine Research Center Tehran University of Medical SciencesTehran ***Iran Neuroscience Institute Tehran University of Medical SciencesTehran ***Iran

Background:Lately,physical activity(PA) in young girls has been frequently discussed,thus we were interested to examine whether a mental training intervention can increase the level of PA in young ***:A sample of 56 girls aged 15.4 ± 0.3 years(mean ± SD) was assigned to either the intervention or control *** then conducted a6-week mental imagery training program on young female *** was evaluated with objective accelerometer *** self-concept was also assessed in all ***:Young females' PA increased after a course of mental training compared to female participants in control ***,physical self-concept improved related to mental training ***:Exercise imagery may be an effective method of PA increase besides psychological enhancement in young girls.

关键词： Accelerometer Exercise imagery Girls Psychological competence Youth

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Three dimensional finite element study on torsion extrusion processing of 1050 aluminum alloy

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Transactions of Nonferrous Metals Society of China 2012年第11期22卷 2771-2776页

作者： Ali KHOSRAVIFARD Mohammad JAHEDI amir hossein YAGHTIN Department of Materials Engineering Shiraz Branch Islamic Azad University Department of Materials Science and Engineering School of Engineering Shiraz University

The capability of the torsion extrusion （TE） process as a severe plastic deformation （SPD） method was compared with the conventional forward extrusion （FE） process. The TE and FE processes were successfully performed on AA1050 alloy samples at room temperature. To simulate the above mentioned processes, finite element analysis was carried out using the commercial elasto-plastic finite element analysis ABAQUS/Explicit Simulation. It is shown that load requirement for the TE process is lower than that for the FE process. The equivalent plastic strain calculated by the FEA proved that higher values of strain are imposed to the sample in the TE process. The strain distribution for the TE sample at the final stage of extrusion shows smoother strain gradient in comparison with the one produced by the FE process.

关键词： AA-1050 alloy severe plastic deformation (SPD) torsion extrusion (TE) equivalent plastic strain strain distribution deformation energy

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The necessity for integrating traditional, complementary, and alternative medicine into medical education curricula in Iran

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Journal of Integrative Medicine 2019年第4期17卷 296-301页

作者： Mohammad hossein Ayati Ata Pourabbasi Nazli Namazi Arman Zargaran Zahra Kheiry amir Hooman Kazemi Bagher Larijani Department of Traditional Medicine School of Traditional Medicine Tehran University of Medical Sciences Tehran *** Iran Department of History of Medicine School of Traditional Medicine Tehran University of Medical Sciences Tehran *** Iran Endocrinology and Metabolism Research Center Endocrinology and Metabolism Clinical Sciences Institute Tehran University of Medical Sciences Tehran ***Iran Diabetes Research Center Endocrinology and Metabolism Clinical Sciences Institute Tehran University of Medical Sciences Tehran *** Iran Department of Traditional Pharmacy School of Traditional Medicine Tehran University of Medical Sciences Tehran *** Iran Idea Development and Innovation Center Endocrinology and Metabolism Clinical Sciences Institute Tehran University of Medical Sciences Tehran *** Iran

Background: The use of traditional and complementary medicine (T&CM) is increasing in both developed and developing countries. The school of Persian medicine (PM) in Iran is a comprehensive medical school that is rich in history and has its own special principles, elements, philosophy, and diagnostic and treatment options. Many complementary therapy modalities are also popular and in demand among patients and physicians. The aim of this paper is to provide logic for the policymakers in Iranian medical education to make changes in medical education curricula, particularly on integrating T&CM. Methods: We reviewed the global experience in teaching T&CM to medical students, and highlighting the strengths of PM, described why it is necessary to integrate T&CM into general medicine curricula in Iran. Results: PM is a traditional system of medicine that dates back about 7000 years. Although there are few studies about the safety and effectiveness of PM, research into it has recently been accelerated. There is a suitable opportunity for integrating T&CM with conventional medicine. Physicians should be familiar with T&CM to avoid any contraindications, interactions, and unwanted effects. Conclusion: Traditional medicine is part of Iran's heritage and. thus, needs special attention. Familiarization of physicians with T&CM can help them choose the best treatment options for their patients. To integrate T&CM into the medical education curricula of Iran, a two-credit course has been proposed for implementation across the country.

关键词： Integrative medicine Traditional medicine Complementary medicine Medical education curriculum

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Towards smart self-clearing glaucoma drainage device

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Microsystems & Nanoengineering 2018年第1期4卷 73-84页

作者： Hyunsu Park amir hossein Raffiee Simon W.M.John Arezoo M.Ardekani Hyowon Lee Weldon School of Biomedical Engineering Birck Nanotechnology CenterCenter for Implantable DevicesPurdue UniversityWest LafayetteIN 47907USA School of Mechanical Engineering Purdue UniversityWest LafayetteIN 47907USA Howard Hughes Medical Institute The Jackson LaboratoryBar HarborME 04609USA

For patients who are unresponsive to pharmacological treatments of glaucoma,an implantable glaucoma drainage devices(GDD)are often used to manage the intraocular ***,the microscale channel that removes excess aqueous humor from the anterior chamber often gets obstructed due to biofouling,which necessitates additional surgical *** we demonstrate the proof-of-concept for smart self-clearing GDD by integrating magnetic microactuators inside the drainage tube of *** magnetic microactuators can be controlled using externally applied magnetic fields to mechanically clear biofouling-based obstruction,thereby eliminating the need for surgical *** this work,our prototype magnetic microactuators were fabricated using low-cost maskless photolithography to expedite design *** fabricated devices were evaluated for their static and dynamic mechanical *** transient numerical analysis,the fluid–structure interaction of our microactuator inside a microtube was characterized to better understand the amount of shear force generated by the device ***,the anti-biofouling performance of our device was evaluated using fluorescein isothiocyanate labeled bovine serum *** microactuators were effective in removing proteinaceous film deposited on device surface as well as on the inner surface of the microchannel,which supports our hypothesis that a smart self-clearing GDD may be possible by integrating microfabricated magnetic actuators in chronically implanted microtubes.

关键词： fouling integrating removing

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Liver tonics:review of plants used in Iranian traditional medicine

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Asian Pacific Journal of Tropical Biomedicine 2015年第3期5卷 170-181页

作者： Tahmineh Akbarzadeh Reyhaneh Sabourian Mina Saeedi hossein Rezaeizadeh Mahnaz Khanavi Mohammad Reza shams Ardekani Department of Medicinal Chemistry Faculty of PharmacyTehran University of Medical Sciences Persian Medicine and Pharmacy Research Center Tehran University of Medical Sciences Medicinal Plants Research Center Tehran University of Medical Sciences Faculty of Traditional Medicine Tehran University of Medical Sciences Department of Pharmacognosy.Tehran University of Medical Sciences

Considering the fact that liver is one of the most important organs in our body,it deserves special attention and *** various recommended supplements,complementary and alternative medicines particularly herbal remedies have received much attention owing to their truly healing *** review profits from Iranian traditional medicine and presents advantageous herbal guide directions for liver *** to credible Iranian medical literature such as Al Qanun Fil ***-Havi and Makhzan-al-Aadvia.a wide spectrum of plants have been found to be useful for cleansing and protecting the *** herbs such as ghafes(Agrimonia eupatoria),kasni(Cichorium intybus),anar(Punica granatum),darchin(Cinnamomum zeylanicum),za'feran(Crocus sativus),gole-sorkh(Rosa damascena) and zereshk(Berberis vulgaris) appeared to get strong consideration and were well documented as outstanding liver *** conducted a comprehensive review of available Iranian medical resources such as scientific information database and medical sciences databases which cover all in vitro and in vivo studies of medicinal plants as liver tonics and hepatoprotcctive *** survey was accomplished using multiple databases including PubMed,ISI web of knowledge,and Google Scholar.

关键词： Iranian traditional medicine Liver tonic Hepatoprotective agents Herbal medicine

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Kinetic modeling of cement slurry synthesized with Henna extract in oil well acidizing treatments

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Petroleum 2016年第2期2卷 196-207页

作者： amir hossein Aghajafari Seyed Reza Shadizadeh Khalil Shahbazi Hadi Tabandehjou Department of Petroleum Engineering Ahwaz Faculty of Petroleum EngineeringPetroleum University of TechnologyAbadanIran National Iranian Drilling Company(NIDC) AhwazIran

Acidizing treatment in petroleum reservoirs is a short-term and viable strategy to preserve the productivity of a *** is a major concern for the degradation of cement sheath integrity,leading to poor zonal isolation and environmental ***,it is essential to understand how the cement behaves when attacked by hydrochloric *** this study,a cement slurry by incorporation of the Henna extract,as an environmentally friendly cement additive,was synthesized as a potential solution to solve this *** characteristics of the treated cement slurry were compared with a reference slurry(w/c?0.44)which is composed of only cement and water.A kinetic study was carried out to evaluate the adsorption behavior of the cement slurries exposed to an acid solution with 0.1 M HCl in a range of 25 to 55C *** features of the cement slurries were evaluated by multiple analytical techniques such as XRD,FTIR,TG,and DSC *** the experimental data,it is concluded that the second-order Lagergren kinetic model revealed to be the best in describing kinetic isotherms taken,because the margin between experimental and calculated values was minor for this *** results of the characterization and HCl interaction kinetic studies underlined the prominent protective role of Henna extract-modified cement slurry in the enhancement of the cement resistance against acid attack and utilization in environmentally favorable oil well acidizing treatments.

关键词： Oil well cement Henna extract Solid/solution interaction Environment protection Kinetic modeling

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Investigation and evaluation of ultrasound reactor for reduction of fungi from sewage

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2007年第7期8卷 493-497页

作者： DEHGHANI Mohammad Hadi MAHVI amir hossein JAHED Gholam Reza SHEIKHI Razieh Department of Environmental Health Engineering School of Public Health Medical Sciences/University of Tehran P.O. Box 14155-6145 Tehran I.R. Iran

The objective of the investigation was to study the application of ultrasound reactor technology (USRT) as a disin-fectant for reduction of fungi from sewage effluent. Fungi are carbon heterotrophs that require preformed organic compounds as carbon sources. USRT is an attractive means to improve water quality because of the system simplicity and no production of toxic by-products. An ultrasound reactor produces strong cavitation in aqueous solution causing shock waves and reactive free radicals by the violent collapse of the cavitation bubble. These effects should contribute to the physical disruption of microbial structures and inactivation of organisms. There was significant reduction in fungal growth, with decreased fungal growth with increasing USRT. In this study, ultrasound irradiation at a frequency of 42 kHz was used to expose suspensions of fungi to evaluate the disinfection efficacy of the ultrasound reactor. Also, this study showed that in this system more than 99% reduction of sewage fungi was achieved after 60 min.

关键词： Ultrasound reactor Sewage Fungi Cavitation Frequency

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A novel Ga(Ⅲ)coordination complex as an efficient sensitizer for enhancing photocatalytic activity of TiO_(2)/rGO nanocomposite

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Journal of Rare Earths 2023年第7期41卷 1004-1013,I0002页

作者： amir hossein Cheshme Khavar Neda Khedri Rubén Rizo Juan Miguel Feliu Martínez Ali Reza Mahjoub Masoumeh Doolabi Ehsan Aghayani Department of Chemistry Farhangian UniversityTehranIran Department of Chemistry Faculty of Basic SciencesTarbiat Modares UniversityTehranIran Instituto de Electroquímica y Departamento de Química Física Universidad de Alicante03080AlicanteSpain Research Center for Environmental Contaminants Abadan University of Medical SciencesAbadanIran Department of Environmental Health Engineering Abadan University of Medical SciencesAbadanIran

Narrow solar-light response range and rapid charges recombination are the main technical barriers in TiO_(2) photocatalysis *** overcome these restrictions,in this work we synthesized a novel binuclear gadolinium(Ⅲ) coordination complex,[Gd_(2)(DPDB)_6(DMF)_6(H_(2)O_()2)](DPDB=[(4-dimethylamino)phenyldiazenyl] benzenesulfonate),which was used as an inorganic sensitizer for boosting the visible light-harvesting and quantum efficiency of TiO_(2) supported-reduced graphene oxide(rGO) *** structure of [Gd_(2)(DPDB)_6(DMF)_6(H_(2)O)_(2)](Gd-CMP) was determined from single-crystal X-ray diffraction data,which indicates three-dimensional(3D) supramolecular architecture through hydrogen bonding and CH…π_(ph) *** prepared nanohybrid(Gd-CMP/TG) reveals significantly enhanced visible-light-induced photocatalytic activity for degradation of acetaminophen(ACT).The complete removal of 10 mg/L ACT is achieved over Gd-CMP/TG,and the corresponding rate constant of ACT degradation of nanohybrid is 40-fold higher than that of bare TiO_(2).In prepared ternary nanohybrid,metal-coordination sensitizer(Gd-CMP) acts as an electron donor,and at the same time,rGO serves as an electron acceptor,and the synergistic effect between them efficiently enhances charges separation and inhibits e/h pair recombination in the hybridized *** radical scavenger tests indicate that the photo-induced O_(2)^(-·) radicals dominate ACT *** the basis of the experimental results and calculated energy of electronic levels,a possible mechanism for the improved photocatalytic activity is discussed.

关键词： Gadolinium Coordination complex Sensitizer Photocatalytic Light-harvesting Rare earths

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Numerical study on cavitation in a globe control valve with different numbers of anti-cavitation trims

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Journal of Central South University 2018年第11期25卷 2677-2687页

作者： Hamidreza YAGHOUBI Seyed amir hossein MADANI Mansour ALIZADEH Department of Mechanical Engineering Iran University of Science and TechnologyTehran 16846-13114Iran

Cavitation is a destructive phenomenon in control *** order to delay cavitation,a multi-series of perforated cylindrical plates,called trims,are ***,the effects of orifice diameter and different types of trims have been *** this study,by numerical analysis,a globe control valve was investigated by employing four different cases(without trim,with one trim,with two and three trims)and the impact of the number of these trims on the intensity,formation region and the initiation point of cavitation was *** was found that the addition of one stage or two stages of trims reduces the intensity and delays the onset of cavitation,relative to the valve without ***,no significant differences in terms of intensity and initiation point of cavitation were observed in the cases where two or three trims were ***,due to the high cost of producing the trims,and the severe drop in flow coefficient,it is not economically and technically justified to increase the number of trims to more than three.

关键词： numerical analysis anti-cavitation trim globe control valve

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