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Evaluation of interleukin 8 +2767 A/T polymorphism in visceral leishmaniasis

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Asian Pacific Journal of Tropical Medicine 2016年第11期9卷 1053-1055页

作者： alireza ahmadi Mehrdad Hajilooi Ghasem Solgi Mohammad Abasi Ahad Bazmani alireza Khalilian Mohammad Matini Khosro Sardarian Department of Internal Medicine School of MedicineHamadan University of Medical Sciences Department of Immunology Faculty of Medicine Hamadan University of Medical Sciences

Objective:To evaluated the relationship between the genetic variations at IL-8 +2767 position with VL pathogenesis among Iranian ***:Three groups including patients with VL clinical presentation and leishmania seropositive(n=124).patients seropositive but without clinical presentation(n=82) and healthy controls(n=63) were selected to conduct this cross-sectional *** at +2767 position of IL-8 was investigated using PCR-RPLP ***-leishmania antibody titration was evaluated by the immunoflorescence ***:We observed higher significant frequencies +2767 A/A and A/T genotypes in groups I compared to group 2 and healthy controls(P=0.001).Also,patients in Group 1 carriyng A/A genotype showed higher liter of antileshmania antibody than patients with A/T and T/T genotypes(P=0.05).The validity of the data was analyzed using Hardy-Weinberg equilibrium and one way analysis of variance(ANOVA),as well as x^***:Our findings indicate that the IL-8 +2767 polymorphism is significantly involved in impaired immune responses against VL and it could be considered as a risk factor for the VL progress.

关键词： Interleukin 8 Polymorphism Visceral leishmaniasis

Analysis of Linear and Nonlinear Vibrations of Composite Rectangular Sandwich Plates with Lattice Cores

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Computers, Materials & Continua 2025年第1期82卷 223-257页

作者： alireza Moradi alireza Shaterzadeh Faculty of Mechanical Engineering Shahrood University of TechnologyShahroodP.O.Box ***Iran

For the first time,the linear and nonlinear vibrations of composite rectangular sandwich plates with various geometric patterns of lattice core have been analytically examined in this *** plate comprises a lattice core located in the middle and several homogeneous orthotropic layers that are symmetrical relative to *** this purpose,the partial differential equations of motion have been derived based on the first-order shear deformation theory,employing Hamilton’s principle and Von Kármán’s nonlinear displacement-strain ***,the nonlinear partial differential equations of the plate are converted into a time-dependent nonlinear ordinary differential equation(Duffing equation)by applying the Galerkin *** the solution of this equation,the natural frequencies are ***,to calculate the non-linear frequencies of the plate,the non-linear equation of the plate has been solved analytically using the method of multiple ***,the effect of some critical parameters of the system,such as the thickness,height,and different angles of the stiffeners on the linear and nonlinear frequencies,has been analyzed in *** confirmthe solution method,the results of this research have been compared with the reported results in the literature and finite elements in ABAQUS,and a perfect match is *** results reveal that the geometry and configuration of core ribs strongly affect the natural frequencies of the plate.

关键词： Free vibration composite sandwich plate lattice core galerkin method Duffing equation multiple scales method

Context-dependency in medicine:how neuronal excitability influences the impact of dopamine on cognition

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Neural Regeneration Research 2025年第11期20卷 3225-3226页

作者： Mahboubeh ahmadi Nahid Rouhi Javad Mirnajafi-Zadeh Bechara J.Saab Department of Physiology Faculty of Medical SciencesTarbiat Modares UniversityTehranIran Mobio Interactive Pte.Ltd. SingaporeRepublic of Singapore

Dopamine,often termed the"feel-good"neurotransmitter,plays a crucial role in myriad physiological and psychological brain *** dopamine is primarily associated with pleasure,reward,and motivation,its effects can be quite complex;and this complexity is further compounded when examining how dopamine functions in typical versus disease-affected neural *** pa rticula r,epilepsy,characte rized by heightened brain excitability,is linked to cognitive dysfunction,and dopamine is implicated in elements of both its pathology and *** has been successful in describing the synaptic abnormalities believed to contribute to memory issues in epilepsy,aiding in the search for effective therapies for what persists as a major medical issue.

关键词： dopamine epilepsy primarily

Segregation behavior of a ternary mixture of titanium dioxide particles in a pseudo two-dimensional fluidized bed

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Particuology 2021年第1期19卷 78-90页

作者： Mojtaba Rasteh alireza Bahramian Goodarz ahmadi Department of Chemical Engineering Hamedan University of TechnologyHamedanP.O.Box65155-579Iran Department of Mechanical and Aeronautical Engineering Clarkson UniversityPotsdamNY 13699-5725USA

The segregation behavior of a mixture of silica-coated titanium dioxide(TiO2)particles of three different sizes in a pseudo two-dimensional fluidized bed was studied experimentally by the freeze-sieving method and numerically by the multi-fluid model(MFM).Three-dimensional computational fluid dynamics(CFD)simulations were carried out to evaluate the effects of the solid wall boundary conditions on particle segregation in terms of specularity and particle-wall restitution *** quantitative indexes of segregation tendency and segregation degree were used to determine the axial segregation of the mixture in triangular *** simulation results revealed that the axial segregation increased with the specularity coefficient,whereas the particle-wall restitution coefficient had a minor effect on axial *** of the simulation results with experimental data showed that the appropriate value of the specularity coefficient used in the CFD model depended on superficial gas *** study of the effects of superficial gas velocity on segregation behavior demonstrated that the greatest segregation was obtained at minimum fluidization velocity and the segregation decreased as the gas velocity gradually increased.

关键词： Ternary mixture Segregation tendency Segregation degree Two-fluid model Computational fluid dynamics(CFD)

Multiple damage detection in complex bridges based on strain energy extracted from single point measurement

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Frontiers of Structural and Civil Engineering 2020年第3期14卷 722-730页

作者： alireza ARABHA NAJAFABADI Farhad DANESHJOO Hamid Reza ahmadi Department of Structural Engineering RoadHousing&Urban Development Research CenterTehran 13145-1696Iran Department of Structural Engineering Faculty of Civil and Environmental EngineeringTarbiat Modares UniversityTehran 14115-397Iran Department of Civil Engineering Faculty of EngineeringUniversity of MaraghehMaragheh 55136-553Iran

Strain Energy of the structure can be changed with the damage at the damage *** accurate detection of the damage location using this index in a force system is dependent on the degree of accuracy in determining the structure deformation function before and after *** use of modal-based methods to identify damage in complex bridges is always associated with problems due to the need to consider the effects of higher modes and the adverse effct of operational conditions on the extraction of structural modal *** this paper,the deformation of the structure was determined by the concept of influence line using the Betti-Maxwell *** two damage detection indicators were developed based on strain energy *** indices were presented separately for bending and torsion *** element analysis of a five-span concrete curved bridge was done to validate the stated *** was simulated by decreasing stiffness at different sections of the *** response regarding displacement ofa point on the deck was measured along each span by passing a moving load on the bridge at very low *** of the strain energy extracted from displacement influence line and the strain energy extracted from the rotational displacement influence line(SERIL)were calculated for the studied *** results show that the proposed methods have well identified the location of the damage by significantly reducing the number of sensors required to record the ***,the location of symmetric damages is detected with high resolution using SERIL.

关键词： damage detection strain energy infuence line complex bridges rotation displacement

An experimental approach for measuring carbon dioxide diffusion coefficient in water and oil under supercritical conditions

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Chinese Journal of Chemical Engineering 2021年第6期34卷 160-170页

作者： Mohammad Sadegh Sharafi Mehdi Ghasemi Mohammad ahmadi alireza Kazemi Department of Petroleum Engineering Amirkabir University of Technology–Tehran PolytechnicIran

Several direct or indirect approaches have been proposed to measure diffusion coefficient of gases into *** main complexity of indirect techniques such as pressure decay method is interpreting early pressure-time data which strongly affected by incubation period effect or convective *** the current approach,accurate apparatus and precise experimental setup including a high pressure and temperature PVT cell,a high precision Sanchez pump,heating and recording sub-system are implemented and a novel data analysis procedure is applied to modify pressure decay *** effect of incubation period is reduced remarkably and diffusion coefficient of carbon dioxide in water in wide range of pressures and temperatures is determined and the effects of temperature,pressure and carbon dioxide phase alteration from gas to supercritical are investigated and the value of uncertainty is ***,diffusion coefficient of CO_(2) and methane in an oil sample from one of the Iranian southwest oil formations is determined precisely using the experimental approach while no incubation period is *** results showed that incubation period duration decreases with increasing diffusion ***,when CO_(2) state is gas,rate of increasing diffusion coefficient with pressure is decreased with temperature and when CO_(2) state is supercritical,the rate of increasing diffusion coefficient with pressure is decreased significantly.

关键词： Diffusion coefficient Modified pressure decay method Incubation period Solubility uncertainty

Investigation on the Effect of Geometrical and Geotechnical Parameters on Elongated Offshore Piles Using Fuzzy Inference Systems

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China Ocean Engineering 2017年第3期31卷 378-388页

作者： Ali AMINFAR alireza MOJTAHEDI Hamid ahmadi Mohammad Hossain AMINFAR Civil Engineering Department Islamic Azad UniversityTabriz Branch Faculty of Civil Engineering University of Tabriz

Among numerous offshore structures used in oil extraction, jacket platforms are still the most favorable ones in shallow waters. In such structures, log piles are used to pin the substructure of the platform to the seabed. The pile＇s geometrical and geotechnical properties are considered as the main parameters in designing these structures. In this study, ANSYS was used as the FE modeling software to study the geometrical and geotechnical properties of the offshore piles and their effects on supporting jacket platforms. For this purpose, the FE analysis has been done to provide the preliminary data for the fuzzy-logic post-process. The resulting data were implemented to create Fuzzy Inference System （FIS） classifications. The resultant data of the sensitivity analysis suggested that the orientation degree is the main factor in the pile＇s geometrical behavior because piles which had the optimal operational degree of about 5° arc more sustained. Finally, the results showed that the related fuzzified data supported the FE model and provided an insight for extended offshore pile designs.

关键词： pile soil FEM offshore jacket platform pile-soil interaction, ^-logic fuzzification

A laboratory study of a novel bio-based nonionic surfactant to mitigate clay swelling

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Petroleum 2021年第2期7卷 178-187页

作者： Saeed Khezerloo-ye Aghdam alireza Kazemi Mohammad ahmadi Department of Petroleum Engineering Amirkabir University of Technology(AUT)Iran

This study reports the applicability of quillaja saponin(QS)as a vigorous and environmentally friendly shale swelling *** is a natural surfactant,which is extracted from herbal *** inhibition strength of this surfactant was assessed through various experiments,such as sedimentation,inhibition,filtration,particle size,Scanning Electron Microscope(SEM)images,and cutting *** obtained from these tests illustrated that QS greatly inhibits clays from *** optimal concentration for QS in this intend was 10 g/*** of this surfactant with other common additives was also investigated,which showed that it is totally ***,the potential inhibition mechanism was assessed through thermal gravimetric analysis(TGA),zeta potential,and contact angle measurement *** coating,and wettability alteration of clay particles to the oil-wet state was recognized as the most probable mechanism.

关键词： Clay swelling Quillaja saponin Wettability alteration Bio-based surfactant

Studying the effect of surfactant assisted low-salinity water flooding on clay-rich sandstones

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Petroleum 2024年第2期10卷 306-318页

作者： Saeed Khezerloo-ye Aghdam alireza Kazemi Mohammad ahmadi Department of Petroleum Engineering Amirkabir University of Technology(AUT)TehranIran Department of Petroleum and Chemical Engineering College of EngineeringSultan Qaboos UniversityMuscatOman

Sandstone reservoirs often contain clay particles that can cause damage and reduce permeability during low-salinity water *** this study,the effect of surfactants on fine migration in clay-rich sandstones and its impact on oil recovery was ***,the impact of surfactants on interparticle forces in fine-matrix,fine-fine,and oil-matrix systems was *** results showed that both CTAB(cetyltrimethyl ammonium bromide)and QS(quillaja saponin)cause EDL compaction,weakening the repulsive ***,SDS(sodium dodecyl sulfate)and TX(triton X-100)do not affect the ***,the effect of surfactants on IFT reduction and wettability alteration was experimentally *** surfactants reduced IFT due to the surface excessive concentration *** wettability alteration experiment illustrated that although QS and CTAB compact EDL around oil and matrix particles leading to attraction force augmentation,they both alter wettability through adsorption on matrix and carboxylic groups present in crude oil,*** aqueous solutions were then injected into various clay-rich sandstone sanpacks,which resulted in increased oil ***,the mechanisms leading to enhanced oil recovery variedby surfactant *** increased recovery by 10%through IFT reduction and wettability alteration,while SDS and TX increased recovery by 12%and 9%,respectively,through wettability alteration and extreme fine *** contrast,partial fine migration in the QS flooding experiment reached a recovery increase of 18%.Permeability trends through experiments were also *** CTAB injection,permeability did not reduce,while QS aqueous solution reduced rock permeability to 5 m *** and TX reduced the magnitude of permeability to 2 m *** conclusion,this study demonstrates that surfactants can effectively improve oil recovery in clay-rich sandstones by altering the interparticle forces,reducing IFT,and changing *** results

关键词： Surfactant flooding Smart water Fine migration Recovery factor