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Indige.tible.fraction of guava fruit:Phe.olic profile.colonic fe.me.tation and e.fe.t on HT-29 ce.ls

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Food Bioscie.ce 2022年第2期46卷 563-571页

作者： Francisco J.Blancas-Be.ite. Jara P´e.e.-Jim´e.e. JAdriana Sa˜nudo-Barajas Nuria e.Rocha-Guzm´an Gustavo A.Gonz´alez-Aguilar Jusce.ino Tovar Sonia G.S´ayago-Aye.di Te.nol´ogico Nacional de.M´e.ico/Instituto Te.nol´ogico de.Te.ic Laboratorio Integral de Investigaci´on en AlimentosAv.Tecnol´ogico 2595CP 63175TepicNayaritMexico Institute.of Food Scie.ce Technology and Nutrition(ICTAN-CSIC)Jos´e Antonio Novais 1028040MadridSpain Ce.tro de.Inve.tigaci´on e. Alime.taci´on y De.arrollo A.C.Unidad Culiac´an.ApdoPostal 32-A.80129Culiac´anSinaloaMexico Te.nol´ogico Nacional de.M´e.ico/Instituto Te.nol´ogico de.Durango Departamento de Ingenierías Química y Bioquímica BlvdFelipe Pescador 1830Ote.Col.Nueva VizcayaCP 3408078000DurangoDgo.Mexico Coordinaci´on de.Te.nología de.Alime.tos de.Orige. Ve.e.al Lab.de Antioxidantes y Alimentos FuncionalesCentro de Investigaci´on en Alimentaci´on y DesarrolloA.C.Carretera a la Victoria Km 0.6Col.La VictoriaHermosillo Sonora83000Mexico De.artme.t of Food Te.hnology Engineering and NutritionLund UniversityP.O.Box 124SE-22100LundSweden

Guava fruit is rich in phe.olic compounds(PCs),whose.me.abolic fate.has not be.n ***-dige.tible.carbohydrate. and PCs in whole.guava(WG)and se.dle.s guava(SG)we.e.submitte. to an in vitro colonic fe.me.tation,followe. by e.aluation of the.anti-prolife.ative.activity of the.fe.me.tation e.tracts in HT-29 cance. ce.l *** main PCs in both sample. we.e.+)-gallocate.hin and gallic acid,while.procyanidin B was the.most abundant one.associate. with soluble.indige.tible.fraction and que.ce.in pre.ominate. in the.insoluble.indige.tible.*** fe.me.tability inde. at 24 h was 78.84%in WG and 84.74%for SG,ne.r to the.value.for raffinose.use. as re.e.e.ce.with butyric acid as the.main short chain fatty acids(SCFA)*** gre.te.t antiprolife.ative.e.fe.ts we.e.obse.ve. in the.SG at 12 h of fe.me.tation and WG at 24 h of *** re.ults allow to sugge.t consumption of guava fruit,e.the. with or without se.ds,as a fe.sible.way to maintain colonic he.lth.

关键词： Short chain fatty acids(SCFA) Phe.olic compounds Indige.tible.fraction In vitro colonic fe.me.tation Antiprolife.ative Psidium guajava L

Switching and e.e.gy-storage.characte.istics in PLZT 2/95/5 antife.roe.e.tric ce.amic syste.

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Journal of Advance. Die.e.trics 2016年第4期6卷 1-4页

作者： A.Pe.aiz-Barranco Y.Me.de.-Gonzalez J.D.S.Gue.ra Xiucai Wang Tongqing Yang Facultad de.Fisica-IMRe Universidad de La Habana San Lazaroy LVedadoLa Habana 10400Cuba Grupo de.Fe.roe.e.ricos e.Mate.iais Multifuncionais Instituto de Fsica Universidade Federal de Uberlandia38408-100Uberlandia-MGBrazil Functional Mate.ials Re.e.rch Laboratory College for Materials Science and EngineeringTongji University4800 CaoanShanghai 201804P.R.China

Switching me.hanisms and e.e.gy-storage.prope.tie. have.be.n inve.tigate. in(Pb_(0.98)La_(0.02)T(Zr_(0.95)Ti_(0.05)T_(0.995O_(3)) antife.roe.e.tric *** e.e.tric fie.d de.e.de.ce.of polarization(P–e.hyste.e.is loops)indicate. that both the.fe.roe.e.tric(Fe.and antife.roe.e.tric(AFe.phase. coe.ist,be.ng the.AFe.more.stable.above.100℃.It has be.n obse.ve. that the.te.pe.ature.has an important influe.ce.on the.switching *** the.othe. hand,the.e.e.gy-storage.de.sity,which has be.n calculate. from the.P–e.hyste.e.is loops,shows value. highe. than 1 J/cm^(3) for te.pe.ature. above.100℃ with around 73%of e.ficie.cy as *** prope.tie. indicate.that the.studie. ce.amic syste. re.e.ls as a promising AFe.mate.ial for e.e.gy-storage.de.ice. application.

关键词： Antife.roe.e.trics e.e.gy-storage switching.

先兆子痫患者血浆内皮微粒水平高于妊娠高血压患者

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世界核心医学期刊文摘（妇产科学分册） 2005年第3期1卷 18-19页

作者： Gonz'e.e. J.J. alez-Quinte.o V.H. Smarkusky L.P. Jim' 李宁

e.e.ate. plasma e.dothe.ial microparticle.le.e.s have.be.n found to be.e.e.ate. in wome. with pre.clampsia. Howe.e., the.r role.in distinguishing pre.clampsia from ge.tational hype.te.sion re.ains to be.e.ucidate.. The.obje.tive. of this study we.e.to compare.e.dothe.ial microparticle.le.e.s among patie.ts with pre.clampsia, ge.tational hype.te.sion, and he.lthy pre.nant control subje.ts and to e.aluate.the.e.fe.t of plasma from wome. with pre.clampsia and ge.tational hype.te.sion on the.re.e.se.of e.dothe.ial microparticle. by re.al microvascular e.dothe.ial ce.ls. A prospe.tive.study was conducte. on 52 wome. with pre.clampsia, 20 wome. with ge.tational hype.te.sion, and 38 he.lthy pre.nant control subje.ts. e.dothe.ial microparticle. we.e.me.sure. by flow cytome.ry with fluore.ce.t monoclonal mouse.anti human antibodie. against CD31, CD42b, and ***31+ /42b e.dothe.ial microparticle.le.e.s we.e.10497 ± .5145 counts/μ L in wome. with pre.clampsia ve.sus 6768 ± .1810 counts/μ L in wome. with ge.tational hype.te.sion (P e.ts, CD31+ /42b- e.dothe.ial microparticle.le.e.s we.e.6119 ± 3592 counts/μ L. CD62e. e.dothe.ial microparticle.le.e.s we.e.930 ± .966 counts/μ L in wome. with pre.clampsia ve.sus 822 ± .150 counts/μ L in wome. with ge.tational hype.te.sion (P e.ts, CD62e. e.dothe.ial microparticle.le.e.s we.e.712 ± .160 counts/μ L. Incubation of re.al microvascular e.dothe.ial ce.ls with plasma from wome. with pre.clampsia re.ulte. in a rise.in CD31+ and CD62e. e.dothe.ial microparticle.le.e.s as compare. with wome. with ge.tational hype.te.sion and control subje.ts. e.dothe.ial microparticle.le.e.s are.highe. in wome. with pre.clampsia than in wome. with ge.tational hype.te.sion and control subje.ts. The.me.sure.e.t of e.dothe.ial microparticle. may be.use.ul as a diagnostic tool for pre.clampsia in pre.nant wome..

关键词：妊娠高血压先兆子痫妊娠组微血管内皮细胞有显著性差异流式细胞仪检测

日常家庭刺激物致刺激性接触性皮炎:采用非侵袭性方法评估皮肤对刺激物反应的种族差异性

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世界核心医学期刊文摘（皮肤病学分册） 2006年第5期2卷 2-2页

作者： Astne. S. Burne.t N. Rius-Daz F. S. Gonz'alez 任建文 Me.orial Sloan Ke.te.ing Cance. Ce.te. Rockefeller Outpatient Pavilion 160 E 53rd St New York NY 10022 United States Dr.

Obje.tive. This study was unde.take. to inve.tigate.the.e.hnic susce.tibility to irritant contact de.matitis induce. by a common dishwashing liquid using noninvasive.te.hnologie.. Me.hods: A total of 30 participants (15 Caucasian, 15 African Ame.ican) we.e.patch te.te. to grade. conce.trations of a common house.old irritant and e.aluate. using clinical scoring, re.le.tance.confocal microscopy, transe.ide.mal wate. loss, and fluore.ce.ce.e.citation spe.troscopy. Re.ults: At 24 hours, the.conce.tration thre.holds for clinically pe.ce.tible.irritancy we.e.significantly highe. for African Ame.ican compare. with Caucasian participants. Re.le.tance.confocal microscopy showe. stratum corne.m disruption, parake.atosis, and spongiosis; the.e.fe.ture. we.e.more.se.e.e.in Caucasian participants (P ≤ .002). Me.n value. for transe.ide.mal wate. loss we.e.significantly highe. in the.Caucasian group at comparable.clinical score. (P ≤ .005). Fluore.ce.ce.e.citation spe.troscopy showe. a broad e.citation band at 300 nm (e.ission 340 nm) and value. in both groups re.urne. to base.ine.by day 7. Limitations: This pilot study was limite. in scope.and large. studie. are.ne.de. to furthe. e.aluate.e.hnic diffe.e.ce. in irritant contact de.matitis and to de.onstrate.the.applicability of our findings for othe. irritants. Conclusion: Clinical e.aluation, re.le.tance.confocal microscopy, and transe.ide.mal wate. loss showe. significant diffe.e.ce. in the.cutane.us irritant re.ponse.be.we.n both groups sugge.ting a supe.ior barrie. function of African Ame.ican skin. Fluore.ce.ce.e.citation spe.troscopy on the.othe. hand de.onstrate. no diffe.e.ce. in the.hype.prolife.ative.re.ponse.afte. irritant e.posure.and indicate. similar kine.ics for the.two groups.

关键词：非侵袭性刺激物斑贴试验非裔美国人临床评分荧光激发光谱组织学特征角化不全显微镜显示棘

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色素性基底细胞癌之共焦反射显微镜检

世界核心医学期刊文摘（皮肤病学分册） 2006年第5期2卷 51-51页

作者： Chan Age.o A.L. Busam K.J. Be.ve.uto-Andrade.C. S. Gonz'alez 李晓莉 De.matology Se.tion Memorial Sloan Kettering Cancer Center 160 E 53 StNewYorkNY10022 United States Dr.

Background: Re.le.tance.confocal microscopy (RCM) is a high-re.olution imaging tool for in vivo noninvasive.e.aluation of skin le.ions. Obje.tive. We.sought to de.cribe.the.re.e.ant RCM fe.ture. for pigme.te. basal ce.l carcinoma (BCC). Me.hods: Pigme.te. skin le.ions with a diffe.e.tial diagnosis of pigme.te. BCC we.e.image. using de.moscopy and RCM, followe. by e.cision for histologic analysis. Re.ults: RCM de.onstrate. aggre.ations of tightly packe. ce.ls with palisading, forming cordlike.structure. and nodule. with irre.ular borde.s and variable.brightne.s; the.e.re.re.e.te. ne.ts of pigme.te. basaloid tumor ce.ls on histopathology, and blue.gray ovoid are.s on de.moscopy. The.e.tumor ne.ts we.e.associate. with bright de.dritic structure., ide.tifie. histologically as e.the. me.anocyte. or Lange.hans ce.ls, toge.he. with nume.ous bright oval to ste.late.shape. structure. with indistinct borde.s re.re.e.ting me.anophage., and with highly re.ractile.granule. of me.anin. Limitations: The.pigme.te. BCCs image. in this study we.e.pre.ominantly nodular; a diffe.e.t se. or additional crite.ia may be.ne.e.sary for de.e.tion of infiltrative.and me.atypical BCCs. Conclusion: RCM may pe.mit in vivo diagnosis of pigme.te. BCC.

关键词：显微镜检共焦基底样细胞嗜黑色素栅栏状色素性黑色素细胞组织学分析非侵袭性朗格汉斯细胞