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中国旅游发展笔谈——旅游与社会文化变迁(二)

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旅游学刊 2013年第12期28卷 3-4页

作者： Noel B. Salazar 张进福 alexis celeste bunten Jennifer Devine K. Thirumaran 黄宜瑜谢素卿林宛儒秦宇高科 Cultural Mobilities Research IMMRCFaculty of Social SciencesUniversity of LeuvenParkstraat 45Bus 3615BE-3000 LeuvenBelgium Intellectual Property in Cultural Heritage Simon Fraser UniversityBurnaby British Columbia Canada Race and Ethnic Studies Program Whitman CollegeWalla WallaWA99362USA Hospitality & Tourism Management James Cook UniversityAustralia (Singapore Campus)SGP574421Singapore 东海大学景观学系北京第二外国语学院酒店管理学院长春师范大学历史文化学院

制订旅行和度假计划往往牵涉到人类的想象能力或对他者的想象。关于异国他乡群体与地方的诱人形象与话语是如此重要, 以至于一旦没有它们, 旅游将变得稀少——如果并非全部没有的话。旅游者往往被鼓励把自己想象成身处天堂般美境之中, ... 详细信息

制订旅行和度假计划往往牵涉到人类的想象能力或对他者的想象。关于异国他乡群体与地方的诱人形象与话语是如此重要, 以至于一旦没有它们, 旅游将变得稀少——如果并非全部没有的话。旅游者往往被鼓励把自己想象成身处天堂般美境之中, 在那里, 地方景观与人群通过被观察、被感知、被想象, 从而被旅游者所消费。然而, 由于想象总是置身于更广泛的社会文化架构中, 目的地市场营销人员根本无法对其完全掌控。因此, 我把想象界定为能够与人们的个体想象互动、并能被用于意义制造与世界塑造的社会传播的代表性组合体.

关键词：社会文化变迁想象能力旅游发展会意中国市场营销人员社会传播旅游者

The role of MRI in modifying surgical management of colorectal liver metastases:a lesson from the CAMINO trial

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Hepatobiliary Surgery and Nutrition 2024年第5期13卷 837-840页

作者： Marco Palucci celeste Del Basso Fabio Giannone Robotic Oncological and HPB SurgeryAOU SS Antonio e Biagio e Cesare ArrigoAlessandriaItaly

The CAMINO trial by Görgec et al.(1)assessed the added diagnostic value of contrast-enhanced(CE)magnetic resonance imaging(MRI)using gadoxetic acid and diffusion-weighted imaging for patients with colorectal liver metastases(CRLMs)scheduled for curative treatment(surgical resection,thermal ablation,or both).The study explored how often liver(MRI)changes therapeutic strategy compared to using only a CE computed tomography(CT)*** MRI’s widespread use in staging for CRLMs,guidelines remain vague,leaving decisions to the surgeon’s preference and expertise.

关键词： Magnetic resonance imaging(MRI) colorectal liver metastasis(CRLM) CAMINO trial

Leishmaniasis in the knee area

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Asian Pacific Journal of Tropical Medicine 2010年第4期3卷 330-331页

作者： Bava Amadeo Javier Rossi Maria Laura Seley celeste Troncoso Alcides Department of Micology La Plata University Department of Microbiology Parasitology and Infectious DiseasesSchool of MedicineBuenos Aires University

Leishmaniasis is a parasitic infection caused by species leishmaniae,which can produce two types of manifestations:visceral and *** south America cutaneous leishmaniasis is more common than visceral leishmaniasis.A case of primary cutaneous leishmaniasis from Bolivia is presented for its *** patient of our case showed an ulcerated lesion of the knee. Montenegro’s intradermal test was ***-stained touch preparation of the skin biopsy revealed amastigotes inside macrophages,consistent with *** patient was treated with meglumine antimoniate intramuscular(20 mg of Sb+/kg/day) three weeks,with complete cicatrization of the lesion.

关键词： Cutaneous leishmaniasis Skin ulcers Leishmania

IGF1-PI3K-induced physiological cardiac hypertrophy:Implications for new heart failure therapies,biomarkers,and predicting cardiotoxicity

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Journal of Sport and Health Science 2021年第6期10卷 637-647,I0001页

作者： Sebastian Bass-Stringer celeste M.K.Tai Julie R.McMullen Baker Heart and Diabetes Institute MelbourneVIC 3004Australia Department of Physiology Anatomy and MicrobiologyLa Trobe UniversityBundooraVIC 3086Australia Department of Diabetes Central Clinical SchoolMonash UniversityMelbourneVIC 3004Australia Department of Physiology and Department of Medicine Alfred Hospital Monash UniversityMelbourneVIC 3004Australia

Heart failure represents the end point of a variety of cardiovascular *** is a growing health burden and a leading cause of death *** date,limited treatment options exist for the treatment of heart failure,but exercise has been well-established as one of the few safe and effective interventions,leading to improved outcomes in ***,a lack of patient adherence remains a significant barrier in the implementation of exercise-based therapy for the treatment of heart *** insulin-like growth factor 1(IGF1)phosphoinositide 3-kinase(PI3K)pathway has been recognized as perhaps the most critical pathway for mediating exercisedinduced heart growth and ***,we discuss how modulating activity of the IGF1PI3K pathway may be a valuable approach for the development of therapies that mimic the protective effects of exercise on the *** outline some of the promising approaches being investigated that utilize PI3K-based therapy for the treatment of heart *** discuss the implications for cardiac pathology and cardiotoxicity that arise in a setting of reduced PI3K ***,we discuss the use of animal models of cardiac health and disease,and genetic mice with increased or decreased cardiac PI3K activity for the discovery of novel drug targets and biomarkers of cardiovascular disease.

关键词： Cardiac protection Cardiotoxicity Exercise Heart failure IGF1 PI3K Therapies

PSA as the driving biomarker to manage low-and intermediate-risk prostate cancer patients in clinical practice

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Asian Journal of Andrology 2024年第6期26卷 567-568页

作者： Enrico Ricevuto celeste Morgani Fabrizia Seri Gemma Bruera Oncology Territorial Care Unit S.Salvatore HospitalUniversity of L’AquilaL’Aquila 67100Italy Department of Biotechnological and Applied Clinical Sciences University of L’AquilaL’Aquila 67100Italy

Prostate cancer risk stratification relies on several clinical factors. Low-risk patients, characterized by T1–T2a stage, Gleason score (GS) ≤6, and prostate-specific antigen (PSA) <10 ng ml−1, exhibit an excellent prognosis and are suitable for active surveillance (AS). Regular monitoring is essential for these patients, including PSA tests every 3–6 months, annual digital rectal exams (DRE), and prostate biopsies every 6–12 months, followed by less frequent biopsies every 2–5 years. Epstein criteria, which consider GS ≤6, PSA density (PSAD) <0.15 ng ml−2, limited tumor involvement in cores, and absence of high-risk features, help predict pathologic and biochemical relapse-free survival and guide AS management.

关键词： patients clinical cancer

Shaping the future of pediatric liver health:unraveling the impact of the new metabolic-associated fatty liver disease definition

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Hepatobiliary Surgery and Nutrition 2023年第4期12卷 611-615页

作者： Stefano Ciardullo Michela Vergani celeste Ronchetti Gianluca Perseghin Department of Medicine and Surgery University of Milano BicoccaMilanItaly Department of Medicine and Rehabilitation Policlinico di MonzaMonzaItaly

Liver steatosis(i.e.,excessive triglyceride accumulation within the hepatocyte)is a very common finding in both the adult and pediatric *** the latter,epidemiologic data using validated diagnostic techniques(either liver biopsy or ultrasound-based technologies)have shown an alarmingly high prevalence,paralleling the ever-increasing rates of overweight and obesity.

关键词： Nonalcoholic fatty liver disease(NAFLD) metabolic-associated fatty liver disease(MAFLD) pediatrics definition fatty liver

Effects of obesity on breast size,thoracic spine structure and function,upper torso musculoskeletal pain and physical activity in women

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Journal of Sport and Health Science 2020年第2期9卷 140-148页

作者： Julie R.Steele celeste E.Coltman Deirdre E.McGhee Biomechanics Research Laboratory School of MedicineUniversity of WollongongWollongongNSW 2522Australia Research Institute for Sport and Exercise Faculty of HealthUniversity of CanberraCanberraACT 2601Australia

Purpose:This study investigated the effects of obesity on breast size,thoracic spine structure and function,upper torso musculoskeletal pain and physical activity participation in women living independently in the ***:A total of 378 women were divided into 3 groups(Not Overweight:body mass index(BMI)=22.5±0.2 kg/m^2(mean±SE);Overweight:BMI=27.4±0.3 kg/m^2;Obese:BMI=35.4±0.3 kg/m^2).Outcome variables of breast volume(mL),thoracic flexion torque(N·m),thoracic kyphosis(degrees),upper torso musculoskeletal pain(score) and time spent in physical activity(min) were calculated and compared among the 3 groups,adjusting for between-group differences in ***:There was a significant main effect of BMI on all outcome *** classified as Obese displayed significantly larger breasts,had greater thoracic flexion torques and reported less time participating in physical activity relative to the participants who were classified as Not Overweight and *** in the Obese group also displayed significantly more thoracic kyphosis and reported significantly more upper torso musculoskeletal pain compared to their counterparts who were classified as Not ***:This study is the first to demonstrate that increased obesity levels were associated with compromised kyphosis and loading of the thoracic spine,as well as increased symptoms of upper torso musculoskeletal pain and reduced time spent in physical activity in women living in the *** recommend further research to determine whether evidence-based interventions designed to reduce the flexion torque generated on the thoracic spine can improve these symptoms of upper torso musculoskeletal pain and the ability of women with obesity to participate in physical activity.

关键词： Breast volume Obesity Thoracic kyphosis Upper torso loading

Silent circulation of poliovirus in small populations

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Infectious Disease Modelling 2017年第4期2卷 431-440页

作者： celeste Vallejo James Keesling James Koopman Burton Singer Department of Mathematics 1400 Stadium RdUniversity of FloridaGainesvilleFL 32611United States School of Public Health 1415 Washington HeightsAnn ArborMI 48109-2029United States Emerging Pathogens Institute University of FloridaP.O.Box 1000092055 Mowry RoadGainesvilleFL 32610United States University of Florida Department of MathematicsUnited States University of Michigan Department of EpidemiologyUnited States Emerging Pathogens Institute at the University of Florida United States

Background:Small populations that have been isolated by conflict make vaccination and surveillance difficult,threatening polio *** circulation is caused by asymptomatic *** is currently not clear whether the dynamics of waning immunity also influence the risk of silent circulation in the absence of *** circulation can,nevertheless,be present following a declaration of elimination as a result of inadequate acute flaccid paralysis surveillance(AFPS)or environmental surveillance(ES).Methods:We have constructed a stochastic model to understand how stochastic effects alter the ability of small populations to sustain virus circulation in the absence of *** analyzed how the stochastic process determinants of the duration of silent circulation that could have been detected by ES were affected by R0,waning dynamics,population size,and AFPS sensitivity in a discrete individual stochastic model with homogeneous contagiousness and random *** measured the duration of silent circulation both by the interval between detected acute flaccid paralysis(AFP)cases and the duration of circulation until ***:As R0 increased and population size increased,the interval between detected AFP cases and the duration of circulation until elimination *** AFPS detection rates decreased,the interval between detected AFP cases *** was up to a 22%chance of silent circulation lasting for more than 3 years with 100%AFP *** duration of silent circulation was not affected by the waning immunity ***:We demonstrated that small populations have the potential to sustain prolonged silent *** in these areas should be intensified before declaring *** further validate these conclusions,it is necessary to realistically relax the simplifying assumptions about mixing and waning.

关键词： Poliovirus Silent circulation Acute flaccid paralysis surveillance Microsimulation model Gillespie algorithm

Neurocysticercosis causing sudden death:a case report

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Asian Pacific Journal of Tropical Medicine 2010年第8期3卷 669-670页

作者： Martinez Fernanda Seley celeste Marchesi Liliana Fontanarossa Victoria Rodriguez Dominique Troncoso Alcides Department of Microbiology Parasitology and Infectious DiseasesSchool of MedicineBuenos Aires University

We report an acute case of a native man from Bolivia suffered from cephalalgia which rapidly worsened and ended in his sudden and unexpected *** resonance imaging(MRI) of the brain was *** demonstrated on brain MRI scan were consistent with a diagnosis of neurocysticercosis(NCC).An autopsy showed the presence of intraventricular Taenia solium(***) cysts which caused blockage of cerebrospinal fluid and secondary *** to the increasing travel movements of people neurocysticercosis must be considered as a cause of unexplained sudden death.

关键词： Neurocysticercosis Taenia solium Sudden death