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Validating cone-beam computed tomography for peri-implant bone morphometric analysis

Bone Research 2014年第2期2卷 103-109页

作者： Yan Huang Jeroen Van Dessel Maarten Depypere Mostafa EzEldeen alexandru andrei iliescu Emanuela Dos Santos Ivo Lambrichts Xin Liang Reinhilde Jacobs OMFS IMPATH Research Group Department of Imaging & Pathology Faculty of Medicine University of Leuven and Oral & Maxillofacial SurgeryUniversity Hospitals Leuven Leuven Belgium State Key Laboratory of Oral Diseases West China Hospital of Stomatology Sichuan University ESAT/PSI Medical Image Computing KU Leuven Leuven Belgium Faculty of Dentistry UMF Craiova Romania School of Dentistry Pontifical Catholic University of Paraná Curitiba Brazil Biomedical Research Institute Hasselt University Diepenbeek Belgium School of Stomatology Dalian Medical University Dalian China

Cone-beam computed tomography （CBCT） has been recently used to analyse trabecular bone structure around dental implants. To validate the use of CBCT for three-dimensional （3D） peri-implant trabecular bone morphometry by comparing it to two-dimensional （2D） histology, 36 alveolar bone samples （with implants n=27 vs. without implants n=9） from six mongrel dogs, were scanned ex vivo using a high-resolution （80 ~m） CBCT. After scanning, all samples were decalcified and then sectioned into thin histological sections （-6 jim） to obtain high contrast 2D images. By using CTAn imaging software, bone morphometric parameters including trabecular number （Tb.N）, thickness （***）, separation （***） and bone volume fraction （BV/TV） were examined on both CBCT and corresponding histological images. Higher *** and ***, lower BV/TV and Tb.N were found on CBCT images （P〈0.001）. Both measurements on the peri-implant trabecular bone structure showed moderate to high correlation （r=0.65-0.85）. The Bland-Altman plots showed strongest agreement for *** followed by ***, Tb.N and BV/TV, regardless of the presence of implants. The current findings support the assumption that peri-implant trabecular bone structures based on high-resolution CBCT measurements are representative for the underlying histological bone characteristics, indicating a potential clinical diagnostic use of CBCT-based peri-implant bone morphometric characterisation.

关键词： bone CBCT

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Helium Plasma Effects on Polymer Surfaces:from Plasma Parameters and Surface Properties towards Bioengineering Applications

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Chinese Journal of Polymer Science 2024年第8期42卷 1156-1166页

作者： andrei Vasile Nastuta Maria Butnaru Byron Cheatham Ramona Huzum Vasile Tiron Ionut Topala Physics and Biophysics Education Research Laboratory(P&B-EduResLab) Biomedical Science DepartmentFaculty of Medical Bioengineering‘Grigore T.Popa’University of Medicine and Pharmacy IasiM.Kogalniceanu 9-13Iasi 700454Romania Faculty of Medical Bioengineering ‘Grigore T.Popa’University of Medicine and Pharmacy IasiM.Kogalniceanu 9-13Iasi 700454Romania Cytoviva Inc.570 Devall Drive Suite 301Auburn 36832ALUSA Integrated Center of Environmental Science Studies in the North-Eastern Development Region(CERNESIM) Department of Exact and Natural SciencesInstitute of Interdisciplinary Research‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania Research Center on Advanced Materials and Technologies(RAMTECH) Department of Exact and Natural SciencesInstitute of Interdisciplinary Research‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania Iasi Plasma Advanced Research Center(IPARC) Faculty of Physics‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania

Plasma treatment is necessary to optimize the performance of biomaterial *** enhances and regulates the performance of biomaterial su rfaces,creating an effective interface with the human *** treatments have the ability to modify the chemical com position and physical structu re of a surface while leaving its properties *** possess the ability to modify material su rfaces,eliminate contaminants,conduct investigations on cancer therapy,and facilitate wound *** subject of study in question involves the integration of plasma science and technology with biology and *** a helium plasma jet source,applying up to 18 kV,with an average power of 10 W,polymer foils were treated for 60 *** treatment has the ability to alter the chemical composition and physical structure of a su rface while maintaining its *** investigation involved the application of helium plasma at atmospheric pressure to polyamide 6 and polyethylene terephthalate *** inquiry involves monitoring and assessing the plasma source and polymer materials,as well as analyzing the impacts of plasma *** the mean power of the discharge aids in assessing the economic efficacy of the plasma *** discharge in helium at atmospheric pressure has beneficial effects in technology,where it increases the surface free energy of polymer *** biomedicine,it is used to investigate cytotoxicity and cell survival,particularly in direct blood exposure situations that can expedite *** the specific parameters that influence the plasma source in the desired manner for the intended application is of utmost im portance.

关键词： Atmopheric pressure plasmas Plasma-polymer interaction Plasma Medicine Plasma diagnosis Polymer characterization

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“Treat-Repair-Treat”:Management of Left Main Coronary Compression by a Pulmonary Artery Aneurysm in a Patient with Atrial Septal Defect and Significant Pulmonary Hypertension

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Congenital Heart Disease 2023年第1期18卷 67-72页

作者： andrei George Iosifescu Roxana Enache Ioana Marinică Corina Radu Vlad Anton iliescu Carol Davila University of Medicine and Pharmacy Bucharest020021Romania Department of Cardiac Surgery C.C.Iliescu Emergency Institute for Cardiovascular DiseasesBucharest022322Romania Department of Cardiology C.C.Iliescu Emergency Institute for Cardiovascular DiseasesBucharest022322Romania Department of Cardiovascular Anesthesia and Intensive Care C.C.Iliescu Emergency Institute for Cardiovascular DiseasesBucharest022322Romania

Left main coronary compression syndrome(LMCS)may complicate pulmonary artery aneurysms(PAA),usually developed in the context of pulmonary arterial hypertension(PAH).We report the case of a 51-year-old female patient with an atrial septal defect(unsuitable for device closure)complicated by a PAA generating a 90%left main *** significant PAH held us back from immediate *** specific dual PAH-targeted therapy(sildenafil and bosentan),the atrial septal defect could be closed with a unidirectional valved patch;the PAAinduced LMCS was treated by reductive *** postoperative course was ***-up showed clinical improvement,but PAH treatment was still *** three months,coronary angiography showed only an insignificant residual left main stenosis,proving that reductive pulmonary arterioplasty was effective in treating *** PAA requires further evaluation for LMCS,a dangerous but treatable ***“treat-repair-treat”strategy and shunt-closure with a unidirectional valved patch can both improve surgical prospects of LMCS with shunt-related PAH.

关键词： Atrial septal defect pulmonary arterial hypertension pulmonary artery aneurysm left main coronary compression syndrome surgery unidirectional valved patch

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10 PW peak power femtosecond laser pulses at ELI-NP

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High Power Laser Science and Engineering 2022年第3期10卷 25-29页

作者： Christophe Radier Olivier Chalus Mathilde Charbonneau Shanjuhan Thambirajah Guillaume Deschamps Stephane David Julien Barbe Eric Etter Guillaume Matras Sandrine Ricaud Vincent Leroux Caroline Richard François Lureau andrei Baleanu Romeo Banici andrei Gradinariu Constantin Caldararu Cristian Capiteanu andrei Naziru Bogdan Diaconescu Vicentiu Iancu Razvan Dabu Daniel Ursescu Ioan Dancus Calin alexandru Ur Kazuo ATanaka Nicolae Victor Zamfir Thales LAS France 78990ÉlancourtFrance Thales Systems Romania 060071 BucurestiRomania Extreme Light Infrastructure-Nuclear Physics IFIN-HH077125 MagureleRomania Physics Doctoral School Bucharest University077125 MagureleRomania Laser Engineering Osaka UniversityOsaka 565-0871Japan

We report on the generation and delivery of 10.2 PW peak power laser pulses,using the High Power Laser System at the Extreme Laser Infrastructure–Nuclear Physics *** this work we demonstrate for the first time,to the best of our knowledge,the compression and propagation of full energy,full aperture,laser pulses that reach a power level of more than 10 PW.

关键词： high-power laser ultra-short laser pulses

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Assessment of recharge capacity potential of groundwater using comparative multi-criteria decision analysis approaches

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Journal of Geographical Sciences 2022年第4期32卷 735-756页

作者： Ionut MINEA Daniel BOICU Oana-Elena CHELARIU Marina IOSUB andrei ENEA alexandru Ioan Cuza University of Iasi RomaniaFaculty of Geography and Geology alexandru Ioan Cuza University of Iasi RomaniaThe Institute of Interdisciplinary ResearchDepartment of Exact Sciences and Natural Sciences alexandru Ioan Cuza University of Iasi Integrated Centre of Environmental Science Studies in the North Eastern Region-CERNESIM

Groundwater resources have always been some of the most valuable resources of human *** changes and ever-increasing water demands registered in the last century have led to diminishing levels of groundwater reserves,as well as reduced recharging ***,in order to use groundwater aquifers in a sustainable manner,it is required to identify areas with higher replenishing *** current study addresses the issue of generating a map for identifying differently ranked groundwater recharging potential values,in the aquifers of the Moldavian Plain region,*** the purpose of conducting the analysis,maps were created through GIS based multi-criteria Analytic Hierarchy Process(AHP)and Catastrophe Theory(CT),with seven relevant,thematic,spatial layers:precipitation distribution,lithological strata,soil texture,declivity,drainage density,land use and the distribution of groundwater level *** results of the two methods of analysis are *** differences are of maximum 3%,in the case of extreme classes(very bad and very good)and in the case of middle classes the deviation is not greater than 0.4%.Following the validation of the results generated by the two methods that were applied,it was observed that the predictions offered by CT are more *** aspect can be based on the fact that the main factors that contribute to the prediction are *** type of workflow emphasizes the necessity of implementing appropriate groundwater management plans for mitigating reservoir scarcity/depletion,and recommending sustainable solutions for future groundwater exploitation practices.

关键词： analytic hierarchy process catastrophe theory groundwater recharge potential groundwater vulnerability Innovative Trend Analysis

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Antithrombotic treatment tailoring and risk score evaluation in elderly patients diagnosed with an acute coronary syndrome

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Journal of Geriatric Cardiology 2017年第7期14卷 442-456页

作者： alexandru Nicolae Mischie Catalina Liliana andrei Crina Sinescu Gani Bajraktari Eugen Ivan Georgios Nikolaos Chatziathanasiou Michele Schiariti Invasive Cardiology Unit Centre Hospitalier de Montlufon Montlufon France Carol Davila University of Medicine and Pharmacy Bucharest Romania Clinic of Cardiology University Clinical Centre of Kosova Prishtina Republic of Kosovo Comanche Memorial Hospital Lawton USA 5Cardiology Clinic Preveza Greece Cardiology Clinic Preveza Greece Department of Cardiovascular Sciences Sapienza University of Rome Rome Italy

Age is an important prognostic factor in the outcome of acute coronary syndromes (ACS). A substantial percentage of patients who experience ACS is more than 75 years old, and they represent the fastest-growing segment of the population treated in this setting. These patients present different patterns of responses to pharmacotherapy, namely, a higher ischemic and bleeding risk than do patients under 75 years of age. Our aim was to identify whether the currently available ACS ischemic and bleeding risk scores, which has been validated for the general population, may also apply to the elderly population. The second aim was to determine whether the elderly benefit more from a specific pharmacological regimen, keeping in mind the numerous molecules of antiplatelet and antithrombotic drugs, all validated in the general population. We concluded that the GRACE (Global Registry of Acute Coronary Events) risk score has been extensively validated in the elderly. However, the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines) bleeding score has a moderate correlation with outcomes in the elderly. Until now, there have not been head-to-head scores that quantify the ischemic versus hemorrhagic risk or scores that use the same end point and timeline (e.g., ischemic death rate versus bleeding death rate at one month). We also recommend that the frailty score be considered or integrated into the current existing scores to better quantify the overall patient risk. With regard to medical treatment, based on the subgroup analysis, we identified the drugs that have the least adverse effects in the elderly while maintaining optimal efficacy.

关键词：急性冠状动脉综合征药物治疗老年人评分风险患者评价抗血栓药物

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Anatomy of the ρ resonance from lattice QCD at the physical point

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Chinese Physics C 2018年第6期42卷 16-22页

作者：孙玮 andrei alexandru 陈莹 Terrence Draper 刘朝峰杨一玻 Institute of High Energy Physics Chinese Academy of Sciences School of Physics University of Chinese Academy of Sciences Department of Physics George Washington University Department of Physics and Astronomy University of Kentucky Department of Physics and Astronomy Michigan State University

We propose a strategy to access the qq component of the p resonance in lattice QCD. Through a mixed action formalism（overlap valence on domain wall sea）, the energy of the qq component is derived at different valence quark masses, and shows a linear dependence on mπ^2. The slope is determined to be c1 =0.505（3）GeV^-1, from which the valence πρ sigma term is extracted to be σ（πρ）^val= 9.82（6） MeV using the Feynman-Hellman theorem. At the physical pion mass, the mass of the qq component is interpolated to be mρ = 775.9±6.0±1.8 MeV, which is close to the p resonance mass. We also obtain the leptonic decay constant of the qq component to be fρ-=208.5±5.5±0.9 MeV, which can be compared with the experimental value fρ^exp≈221 MeV through the relation fρ^exp=（1/2）Zfρ±, with Zρ≈1.13 being the on-shell wavefunction renormalization of p owing to the ρ-π interaction. We emphasize that mρand fρ of the qq component, which are obtained for the first time from QCD, can be taken as the input parameters of p in effective field theory studies where p acts as a fundamental degree of freedom.

关键词： ρ resonance leptonic decay constant renormalization

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Two Analytical Methods for Detection and Elimination of the Static Hazard in Combinational Logic Circuits

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Circuits and Systems 2013年第7期4卷 466-471页

作者： Mihai Grigore Timis alexandru Valachi alexandru Barleanu andrei Stan Automatic Control and Computer Engineering Faculty Technical University Gh.Asachi Iasi Romania

In this paper, the authors continue the researches described in [1], that consists in a comparative study of two methods to eliminate the static hazard from logical functions, by using the form of Product of Sums (POS), static hazard “0”. In the first method, it used the consensus theorem to determine the cover term that is equal with the product of the two residual implicants, and in the second method it resolved a Boolean equation system. The authors observed that in the second method the digital hazard can be earlier detected. If the Boolean equation system is incompatible (doesn’t have solutions), the considered logical function doesn’t have the static 1 hazard regarding the coupled variable. Using the logical computations, this method permits to determine the needed transitions to eliminate the digital hazard.

关键词： Combinational Circuits Static Hazard Logic Design Boolean Functions

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Logical Function Decomposition Method for Synthesis of Digital Logical System Implemented with Programmable Logic Devices (PLD)

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Circuits and Systems 2013年第7期4卷 472-477页

作者： Mihai Grigore Timis alexandru Valachi alexandru Barleanu andrei Stan Automatic Control and Computer Engineering Faculty Technical University Gh.Asachi Iasi Romania

The paper consists in the use of some logical functions decomposition algorithms with application in the implementation of classical circuits like SSI, MSI and PLD. The decomposition methods use the Boolean matrix calculation. It is calculated the implementation costs emphasizing the most economical solutions. One important aspect of serial decomposition is the task of selecting “best candidate” variables for the G function. Decomposition is essentially a process of substituting two or more input variables with a lesser number of new variables. This substitutes results in the reduction of the number of rows in the truth table. Hence, we look for variables which are most likely to reduce the number of rows in the truth table as a result of decomposition. Let us consider an input variable purposely avoiding all inter-relationships among the input variables. The only available parameter to evaluate its activity is the number of “l”s or “O”s that it has in the truth table. If the variable has only “1” s or “0” s, it is the “best candidate” for decomposition, as it is practically redundant.

关键词： Combinational Circuits Static Hazard Logic Design Boolean Functions Logical Decompositions

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城市节点

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城市环境设计 2016年第5期 312-313页

作者： Arh.andrei-Ovidiu LEFTER Arh.alexandru-Tudor GHERMAN S.C.Lef Proiect S.R.L.

项目实施、集成的虚拟现实与在购物中心增强现实技术的概念是为了创造其他功能空间。这些功能是用来为客户提供一段更愉快的使用时间,同时减少建筑对周边地区的负面影响,是一个综合社会、环境和经济的因素。此方案是主要一个覆盖着ETFE... 详细信息

项目实施、集成的虚拟现实与在购物中心增强现实技术的概念是为了创造其他功能空间。这些功能是用来为客户提供一段更愉快的使用时间,同时减少建筑对周边地区的负面影响,是一个综合社会、环境和经济的因素。此方案是主要一个覆盖着ETFE膜顶的地下设施,里面分为3个区域:外环(社会、文化和经济的混合功能),中庭(一个大的全景观景点和虚拟现实)与快速购物中

关键词：平面图图(数学) 购物中心虚拟现实

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