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Bacteriological Profile of Infections Encountered in a Pneumology Service in a Moderate-Income Country [Pneumology Department of CHU Cocody (Côte d’Ivoire)]

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Open Journal of Respiratory Diseases 2024年第1期14卷 1-11页

作者： Brou Jean Marcel Ahui Alitonde Eudoxie Djegbeton Alima Kone Marc-Olivier Koffi Kouame Clarisse Elogne Mobio Nancy Hermine Benjamin Kouraogo Erick Akouatia Constante Virginie Brou-Gode Kigninlman Horo Boko alexandre Kouassi Ngoran Koffi Pneumology Service Teaching Hospital of Cocody Abidjan C&#244te d’Ivoire Medical School of Abidjan University Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire Pasteur Institute of Cô te d’Ivoire Abidjan C&#244te d’Ivoire

Introduction: Infections represent a real public health problem aggravating the morbidity and mortality of hospitalized patients. Methods: This was a retrospective study with descriptive purposes over a period of 05 years, in the Pneumology Department of the University Hospital of Cocody. Results: The average age in our population was 42 years. We observed a male predo- minance of 64.5%, with a sex ratio of 1.8. Medical history was dominated by HIV infection (23.5%), followed by tuberculosis (15.6%). Concerning lifestyle, smoking was found in 38% of cases. Symptoms progressed chronically in 80% of cases. An infectious syndrome was found in 75% of cases. Microbial culture was positive in 42% of cases. Pseudomonas aeruginosa and Klebsiella pneumoniae were encountered in 26.4% of cases each, followed by Echerichia coli in 10.4% of cases. Klebsiella pneumoniae in the first three years topped the list, but gradually. Pseudomonas aeruginosa maintained its leadership over the last three years. Pseudomonas aeruginosa isolates expressed a resistance rate of 9.8% to ceftazidime and 8.1% to imipenem;to aztreonam (36%), ticarcillin (33.3%) and levofloxacin. These strains were susceptible to fosfomycin (100%), mero- penem (96.6%) and amikacin (96%). For isolated strains of Entero- bacteria- ceae, resistance was observed about ticarcillin (83.3%) and amoxicillin clavula- nic acid (71.2%). Streptococcaceae showed resistance to tetracycline (69.2%) and erythromycin (50%). Over the years there has been an increase in re- sistance to amoxicillin-clavulanic acid ceftriaxone. The death rate was 14%. Conclusion: The bacterial profile of infections is dominated by germs respon- sible for nosocomial infection with significant mortality.

关键词： Bacterial Pleural Pneumonia Nosocomial Infection Sub-Saharan Africa Antibiotic Therapy

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Electrocatalytic production of glycolic acid via oxalic acid reduction on titania debris supported on a TiO_(2)nanotube array

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Journal of Energy Chemistry 2022年第5期31卷 669-678页

作者： Francesco pio Abramo Federica De Luca Rosalba Passalacqua Gabriele Centi Gianfranco Giorgianni Siglinda Perathoner Salvatore Abate Department of ChiBioFarAM(Industrial Chemistry) University of MessinaERIC aisbl and INSTM/CASPEV.le F.Stagno d’Alcontres 31Messina 98166Italy University of Calabria Department of Environmental EngineeringLaboratory of Industrial Chemistry and Catalysis Via P.Bucci87036 RendeCSItaly

Electrodes prepared by anodic oxidation of Ti foils are robust and not toxic materials for the electrocatalytic reduction of oxalic acid to glycolic acid, allowing the development of a renewable energy-driven process for producing an alcoholic compound from an organic acid at low potential and room temperature. Coupled with the electrochemical synthesis of the oxalic acid from CO_(2),this process represents a new green and low-carbon path to produce added value chemicals from CO_(2). Various electrodes prepared by anodic oxidation of Ti foils were investigated. They were characterized by the presence of a TiO_(2) nanotube array together with the presence of small patches, debris, or TiO_(2) nanoparticles. The concentration of oxygen vacancies, the amount of Ti^(3+) measured by X-ray photoelectron spectroscopy(XPS) and the intensity of the anodic peak measured by cyclic voltammetry, were positively correlated with the achieved oxalic acid conversion and glycolic acid yield. The analysis of the results indicates the presence of small amorphous TiO_(2) nanoparticles(or surface patches or debris) interacting with TiO_(2) nanotubes, the sites responsible for the conversion of oxalic acid and glycolic acid yield. By varying this structural characteristic of the electrodes, it is possible to tune the glycolic acid to glyoxylic acid relative ratio. A best cumulative Faradaic efficiency(FE) of about 84% with FE to glycolic acid around 60% and oxalic conversion about 30% was observed.

关键词： Oxalic acid TiO_(2)nanotubes Glyoxylic acid Glycolic acid Electrocatalysis

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Synthesis of hierarchical transition metal oxyhydroxides in aqueous solution at ambient temperature and their application as OER electrocatalysts

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Journal of Energy Chemistry 2022年第8期31卷 89-97,I0003页

作者： Zongkun Chen Xingkun Wang Sascha Keßler Qiqi Fan Minghua Huang Helmut Cölfen University of Konstanz Physical ChemistryUniversitätsstraße 10Konstanz D-78457Germany School of Materials Science and Engineering Ocean University of ChinaQingdao 266100ShandongChina

First-row(3 d)transition metal oxyhydroxides have attracted increasing attention due to their various *** investigating the oxidation mechanism and processing such materials into hierarchical architectures are greatly desired for their further development,it remains unclear how the oxidation state change occurs,and efforts to produce hierarchical oxyhydroxides in compliance with high ecological and economic standards have progressed ***,we describe a facile one-step coprecipitation route for the preparation of hierarchical CoOOH,NiOOH and MnOOH,which involves the diffusion of NH_(3)originating from ammonium hydroxide solution into an aqueous solution containing metal ion salts and K_(2)S_(2)O_(8).Comprehensive characterizations by scanning electron microscope,transmission electron microscopy,X-ray diffraction analysis,X-ray photoelectron spectroscopy,ultraviolet-visible spectroscopy and in situ p H measurement demonstrated that K_(2)S_(2)O_(8)induces the oxidation state change of metal ion species after the start of ***,it was found that,benefiting from the OH–concentration gradient created by the NH_(3)diffusion method and the suitable growth environment provided by the presence of K_(2)S_(2)O_(8)(high nucleation rate and secondary nucleation),the formation of hierarchical oxyhydroxide structures can be realized in aqueous solution at ambient temperature without the use of heat energy and additional structure-directing *** hierarchical CoOOH structures are performed as the electrocatalysts for the oxygen evolution reaction in alkaline media,which exhibit good activity with an overpotential of 320 m V at 10 m A cm^(-2)and a low Tafel slope of 59.6 m V dec^(–1),outperforming many congeneric ***,our study not only provides important insights to understand the formation mechanism of hierarchical oxyhydroxides,but also opens up new opportunities for the preparation of hierarchical oxyhydroxides via a f

关键词： Formation mechanism Hierarchical transition metal oxyhydroxides Aqueous solution Ambient temperature Oxygen evolution reaction

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Man Overboard Detection System Using IoT for Navigation Model

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Computers, Materials & Continua 2022年第6期71卷 4955-4969页

作者： Hüseyin Gürüler Murat Altun Faheem Khan Taegkeun Whangbo Department of Information Systems Engineering Mugla Sitki Kocman UniversityMuglaTurkey Artificial Intelligence Lab Department of Computer EngineeringGachon UniversityKorea

Security measures and contingency plans have been established in order to ensure human safety especially in the floating elements like ferry,roro,catamaran,frigate,yacht that are the vehicles services for the purpose of logistic and passenger *** this paper,all processes in the event of Man overboard(MOB)are initiated for smart *** MOB the falling person is totally dependent on the person who first saw the falling *** main objective of this paper is to develop a solution to this significant *** a staff member or a passenger does not see the fall into the sea,undesirable situations such as disappearance,injury and death can occur during the period until the absence of the fallen person is *** this paper,a comprehensive and improved solution is provided in terms of personnel and passenger security especially in all the floating elements,in which human resources are intensively involved like passengers,freight,logistics,fishing,business,yacht,leisure and naval *** this case,if the ship’s personnel or passengers fall into the sea in any way,it detected the fallen person into the sea by the sensors in the portable emergency device,which each person will *** warning system is activated via the in-ship automation system to which the information is transmitted by wireless ***,the case of MOB will be determined *** of things(IoT)has a key role in identifying the location and information of the person falling into the sea through sensors,radio frequency,GPS and connected ***,the alarm system on board will be activated and MOB flag(Oscar)will automatically be *** paper enables the Search and rescue(SAR)operations to be initiated and accelerated without losing time through decision-making process.

关键词： SAR internet of things man overboard arduino wireless communication smart transportation

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Integrative genomic and transcriptomic profiling of pulmonary sarcomatoid carcinoma identifies molecular subtypes associated with distinct immune features and clinical outcomes

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Cancer Innovation 2024年第3期3卷 81-94页

作者： Sahil Seth Runzhe Chen Yang Liu Junya Fujimoto Lingzhi Hong alexandre Reuben Susan Varghese Carmen Behrens Tina McDowell Luisa Solis Soto Cara Haymaker Annikka Weissferdt Neda Kalhor Jia Wu Xiuning Le Natalie I Vokes Chao Cheng John V.Heymach Don L.Gibbons P.Andrew Futreal Ignacio IWistuba Humam Kadara Jianhua Zhang Cesar Moran Jianjun Zhang Department of Genomic Medicine The University of Texas MD Anderson Cancer CenterHoustonTexasUSA TRACTION The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Graduate School of Biomedical Sciences The University of Texas MD Anderson and the University of Texas Health Science CenterHoustonTexasUSA Department of Thoracic/Head and Neck Medical Oncology The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Epidemiology The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Pathology The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Imaging Physics The University of Texas MD Anderson Cancer CenterHoustonTexasUSA Department of Medicine Baylor College of MedicineHoustonTexasUSA

Background:Pulmonary sarcomatoid carcinoma(PSC)is a rare and aggressive subtype of non-small cell lung cancer(NSCLC),characterized by the presence of epithelial and sarcoma-like *** molecular and immune landscape of PSC has not been well ***:Multiomics profiling of 21 pairs of PSCs with matched normal lung tissues was performed through targeted high-depth DNA panel,whole-exome,and RNA *** describe molecular and immune features that define subgroups of PSC with disparate genomic and immunogenic features as well as distinct clinical ***:In total,27 canonical cancer gene mutations were identified,with TP53 the most frequently mutated gene,followed by ***,most TP53 and KRAS mutations were earlier genomic events mapped to the trunks of the tumors,suggesting branching evolution in most PSC *** identified two distinct molecular subtypes of PSC,driven primarily by immune infiltration and *** Immune High(IM-H)subtype was associated with superior survival,highlighting the impact of immune infiltration on the biological and clinical features of localized ***:We provided detailed insight into the mutational landscape of PSC and identified two molecular subtypes associated with ***-H tumors were associated with favorable recurrence-free survival and overall survival,highlighting the importance of tumor immune infiltration in the biological and clinical features of PSCs.

关键词： genomic immune pulmonary sarcomatoid carcinoma survival

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An Efficient and Reliable Multicasting for Smart Cities

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Computers, Materials & Continua 2022年第7期72卷 663-678页

作者： Faheem Khan Muhammad Zahid Hüseyin Gürüler Ilhan Tarimer Taegkeun Whangbo Department of Computer Engineering Artificial intelligence LabGachon UniversitySeongnam13120Korea Department of Computer Science Bacha Khan University CharsaddaCharsadda24450Pakistan Department of Information Systems Engineering Mugla Sitki Kocman UniversityMugla48000Turkey

The Internet of thing(IoT)is a growing concept for smart cities,and it is compulsory to communicate data between different networks and *** the IoT,communication should be rapid with less delay and *** this purpose,flooding is used for reliable data communication in a smart cities concept but at the cost of higher overhead,energy consumption and packet drop *** paper aims to increase the efficiency in term of overhead and reliability in term of delay by using multicasting and unicasting instead of flooding during packet forwarding in a smart city using the IoT *** this paper,multicasting and unicasting is used for IoT in smart cities within a receiver-initiated mesh-based topology to disseminate the data to the cluster *** cities networks are divided into cluster head,and each cluster head or core node will be responsible for transferring data to the desired *** protocol is a novel approach according to the best of our knowledge,and it proves to be very useful due to its efficiency and reliability in smart cities concept because IoT is a collection of devices and having a similar interest for transmission of *** results are implemented in Network simulator 2(NS-2).The result shows that the proposed protocol shows performance in overhead,throughput,packet drop,delay and energy consumption as compared to benchmark schemes.

关键词： Multicasting unicasting flooding network simulator-2 internet of thing smart cities

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Comparative Study of Transvesical and Retropubic Prostatic Adenomectomies in the Urology-Andrology Department of Ignace Deen University Hospital Center

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Open Journal of Urology 2024年第4期14卷 227-243页

作者： Lahoumbo Ricardo Gnammi Demba Cissé Vahina alexandre Gamamou Daouda Kanté Mamadou Diawo Bah El-Mouksitou Akinocho Sabi Couscous Hassiatou Abdul-Haqq Bah-L’Imam Thierno Oumar Diallo Thierno Mamadou Oury Diallo Ibrahima Bah Abdoulaye Bobo Diallo Oumar Raphiou Bah Department of Urology-Andrology Ignace Deen UHC Conakry Republic of Guinea School of Public Health Free University of Brussels Brussels Belgium Medical Imaging Department Ambroise Pare Clinic Conakry Guinea

Objective: To compare the results of transvesical and retropubic prostatic adenomectomies at the Urology-Andrology Department of Conakry University Hospital. Methodology: This was a prospective multi-operator analytical study lasting 6 months. It included 70 patients operated on for benign prostatic hypertrophy (BPH), divided into 2 groups of 35 according to the retropubic or transvesical technique. The data was collected using a questionnaire and entered into the Epi info application. The analysis was initially descriptive and then univariate. To identify confounding factors, a multivariate analysis was performed. The application conditions of each test were checked before their application. A p-value Results: Upper adenomectomies represented 53.6% of surgeries performed for BPH. The average age was 73.2 years. The mean prostate volume was 117 ± 51.6 cc and the mean total PSA was 9.2 ± 11.4 ng/ml. The majority of patients had an ASA1 (60%) and ASA2 (37.1%) score. Spinal anesthesia, a double-current silicone probe with hinged hinge 22, and drainage of the prevesical space were carried out in all patients, i.e. 100%. The average overall blood loss was 229 ± 98.2 ml. It was lower in the group of patients operated via the retropubic route (187 ± 60.4 ml). The same was true for the duration of intervention (49.1 ± 7.17 vs 55.4 ± 7.9 min), the catheter wearing time (5.14 ± 0.97 vs 9.29 ± 2 .9 days) and the length of hospitalization (=6.26 ± 1.15 vs 12.1 ± 5.74 days). Conclusion: The retropubic technique has advantages over the transvesical one. These advantages are translated by a gain in the duration of the intervention, blood loss, catheter wearing time and length of hospitalization.

关键词： Upper Adenomectomies BPH Retropubic Approach Transvesical Approach Conakry

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Hybrid High‑Order Methods for the Acoustic Wave Equation in the Time Domain

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Communications on Applied Mathematics and Computation 2022年第2期4卷 597-633页

作者： Erik Burman Omar Duran alexandre Ern Department of Mathematics University College LondonLondon WC1E 6BTUK CERMICS Ecole des Ponts77455 Marne la Vallée Cedex 2France INRIA Paris 75589 ParisFrance

We devise hybrid high-order(HHO)methods for the acoustic wave equation in the time *** frst consider the second-order formulation in *** the Newmark scheme for the temporal discretization,we show that the resulting HHO-Newmark scheme is energy-conservative,and this scheme is also amenable to static condensation at each time *** then consider the formulation of the acoustic wave equation as a frst-order system together with singly-diagonally implicit and explicit Runge-Kutta(SDIRK and ERK)***-SDIRK schemes are amenable to static condensation at each time *** HHO-ERK schemes,the use of the mixed-order formulation,where the polynomial degree of the cell unknowns is one order higher than that of the face unknowns,is key to beneft from the explicit structure of the *** results on test cases with analytical solutions show that the methods can deliver optimal convergence rates for smooth solutions of order O(hk+1)in the H1-norm and of order O(h^(k+2))in the L^(2)-***,test cases on wave propagation in heterogeneous media indicate the benefts of using high-order methods.

关键词： Hybrid high-order methods Wave equation Newmark scheme Runge-Kutta scheme

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N-methyl-D-aspartate receptor functions altered by neuronal PTP1B activation in Alzheimer’s disease and schizophrenia models

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Neural Regeneration Research 2022年第10期17卷 2208-2210页

作者： alexandre F.R.Stewart Hsiao-Huei Chen Department of Biochemistry Microbiology and ImmunologyUniversity of Ottawaand University of Ottawa Heart InstituteOttawaONCanada Centre for Infection Immunity and InflammationOttawaONCanada Medicine Cellular and Molecular MedicineUniversity of Ottawa Brain and Mind InstituteOttawa Hospital Research InstituteOttawaONCanada

Glutamate is the main exc i tatory neurotransmitter in the brain and binds to two major classes of receptors,theα-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid(AMPA)and the N-methyl-D-aspartate(NMDA)*** AMPA receptors that are immediately activated by glutamate release,NMDA receptors are blocked by magnesium and can only be activated by glutamate after membrane ***,NMDA receptors are only activated after repeated AMPA receptor activation by *** receptors are,for the most part,calcium-permeable *** influx through NMDA receptors modulates synaptic transmission in neurons based on prior history of excitation,and provides a means of scaling the strength of synapses required for Hebbian plasticity.

关键词： PTP1B aspartate NMDA

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Embedded Atom Method-Based Geometry Optimization Aspects of Body-Centered Cubic Metals

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Chinese Physics Letters 2013年第5期30卷 112-115页

作者： M.Güler E.Güler Department of Physics Hitit University19030 CorumTurkey

We present embedded atom method-based geometry optimization calculations for Fe, Cr, Mo, Nb, Ta, V and W body-centered cubic metals with Finnis–Sinclair potentials. After the optimization, we determine their typical elastic constants, bulk modulus, shear modulus, Young's modulus, Poisson's ratios, elastic wave velocities and cohesive energies. Additionally, we perform a benchmark between the experiments and the available density functional theory results. In general, our results show a good consistency with previous findings on the elastic and cohesive energy properties of the considered metals.

关键词： modulus optimization cubic

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