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In.luen.e of man.facturin. process-in.uced geometrical defects on.the en.rgy absorption.capacity of polymer lattice structures

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Defen.e Techn.logy（防务技术） 2024年第5期35卷 47-59页

作者： alexandre Riot En.ico Pan.ttieri An.on.o Cosculluela Marco Mon.emurro Un.versite de Bordeaux Arts et Metiers Institute of TechnologyCNRSINRABordeaux INPHESAM UniversiteI2M UMR 5295F-33405 TalenceFrance Fren.h Atomic En.rgy Commission Route des GargailsCedexF-33114Le BarpFrance

Modern.additive man.facturin. processes en.ble fabricatin. architected cellular materials of complex shape,which can.be used for differen. *** them,lattice structures are in.reasin.ly used in.application. requirin. a compromise amon. lightn.ss an. suited mechan.cal properties,like improved en.rgy absorption.capacity an. specific stiffn.ss-to-weight an. stren.th-to-weight ratios.A dedicated modelin. strategy to assess the en.rgy absorption.capacity of lattice structures un.er un.-axial compression.loadin. is presen.ed in.this *** n.merical model is developed in.a n.n.lin.ar framework accoun.in. for the strain.rate effect on.the mechan.cal respon.es of the lattice *** geometries,i.e.,cubic body cen.ered cell,octet cell,rhombic-dodecahedron.an. trun.ated cuboctahedron.2+,are ***,the in.luen.e of the relative den.ity of the represen.ative volume elemen. of each geometry,the strain.rate depen.en.y of the bulk material an. of the presen.e of the man.facturin. process-in.uced geometrical imperfection. on.the en.rgy absorption.capacity of the lattice structure is *** main.outcome of this study poin.s out the importan.e of correctly in.egratin. geometrical imperfection. in.o the modelin. strategy when.shock absorption.application. are aimed for.

关键词： Lattice structures Architected cellular materials Dyn.mic simulation En.rgy absorption Geometrical imperfection Additive man.facturin.

Simulated rain.all in.Brazil:An.altern.tive for assesmen. of soil surface processes an. an.opportun.ty for techn.logical developmen.

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In.ern.tion.l Soil an. Water Con.ervation.Research 2024年第1期12卷 29-42页

作者： Camila Calazan. da Silva Luz Wilk Sampaio de Almeida Adilson.Pacheco de Souza n.valdo Schultz Jamil alexandre Ayach An.che Dan.el Fon.eca de Carvalho Postgraduate Program in.Agron.my-Soil Scien.es Federal Rural University of Rio de JaneiroSeropédicaRJBrazil Agron.my Departmen. Federal Institute of EducationScience and Technology of RondôniaAriquemesROBrazil Federal Un.versity of Mato Grosso SinopMTBrazil Federal Rural Un.versity of Rio de Jan.iro SeropédicaRJBrazil Federal Un.versity of Mato Grosso do Sul Campo GrandeMSBrazil

Rain.all simulators(RS)have been.used,above all,to evaluate hydrological processes related to soil water in.iltration.surface run.ff an. soil *** allow repeatability of rain.application.with differen. precipitation.in.en.ities in.field an./or laboratory con.ition. an. should produce even.s with physical characteristics similar to n.tural *** this man.script,we carried out a bibliometric an. scien.ometric an.lysis of studies with simulated rain.all in.Brazil to assess the temporal evolution.of publication.,the main.topics addressed an. the degree of techn.logical developmen. of the *** searched for the terms“rain.all simulator”OR“simulated rain.all”An.“Brazil”in.the Scopus,Web of Scien.e,SciELO an. Google Scholar *** foun. 143 articles published in.the last 37 years(1985-2022).Our fin.in.s in.icate that the main.research areas covered in.papers are soil erosion.57.34%),soil water in.iltration.24.47%),n.trien. losses(9.8%)an. RS developmen. an. calibration.assessmen.(8.39%).In.recen. years,the n.mber of published papers in.in.ern.tion.l high-impact factor journ.ls has *** of the papers(49.65%)refer to studies carried out by in.titution. located in.the south an. southeast region. of ***,there is a large gap of studies on.simulated rain.all in.other region. of Brazil,where importan. biomes such as the Cerrado,Amazon.Caatin.a,an. their tran.ition. are *** study in.orms research priorities on.soil erosion.un.er simulated rain.all an. provides a bibliographic database that can.assist in.more detailed future an.lyses.

关键词： Rain.all simulator Soil an. water losses Soil water in.iltration Bibliometrics Scien.ific review

Cerebral an. muscle tissue oxygen.tion.durin. exercise in.healthy adults: A systematic review

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Journ.l of Sport an. Health Scien.e 2024年第4期13卷 459-471,F0003页

作者： Diego Orcioli-Silva Victor Spian.or Beretta Paulo Cezar Rocha San.os Felipe Marron. Rasteiro An.ta Brum Marostegan.Rodrigo Vitorio Claudio alexandre Gobatto Fulvia Barros Man.hado-Gobatto Laboratory of Applied Sport Physiology(LAFAE) School of Applied Sciences(FCA)University of Campinas(UNICAMP)Limeira 13484-350Brazil Posture an. Gait Studies Laboratory(LEPLO) Institute of BiosciencesSao Paulo State University(UNESP)Rio Claro 13506-900Brazil Physical Education.Departmen. School of Technology and SciencesSao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil Departmen. of Computer Scien.e&Applied Mathematics Weizmann Institute of ScienceRehovot 7610001Israel Cen.er of Advan.ed Techn.logies in.Rehabilitation Sheba Medical CenterRamat Gan 5265601Israel Departmen. of Sport Exercise and RehabilitationNorthumbria UniversityNewcastle upon Tyne NE18STUK

Backgroun.:n.ar-in.rared spectroscopy(n.RS)techn.logy has allowed for the measuremen. of cerebral an. skeletal muscle oxygen.tion.simultan.ously durin. *** this techn.logy has been.growin. an. is n.w successfully used in.laboratory an. sports settin.s,this systematic review aimed to syn.hesize the eviden.e an. en.an.e an.in.egrative un.erstan.in. of bloodﬂow adjustmen.s an. oxygen.O_(2))chan.es(i.e.,the balan.e between.O_(2) delivery an. O_(2) con.umption.within.the cerebral an. muscle systems durin. ***:A systematic review was con.ucted usin. PubMed,Embase,Scopus,an. Web of Scien.e databases to search for relevan. studies that simultan.ously in.estigated cerebral an. muscle hemodyn.mic chan.es usin. the n.ar-in.rared spectroscopy system durin. *** review con.idered man.scripts written.in.En.lish an. available before February 9,*** step of screen.n. in.olved evaluation.by 2 in.e-pen.en. authors,with disagreemen.s resolved by a third *** Joan.a Briggs In.titute Critical Appraisal Checklist was used to assess the methodological quality of the ***:Twen.y studies were in.luded,of which 80%had good methodological quality,an. in.olved 290 youn. or middle-aged *** types of exercises were used to assess cerebral an. muscle hemodyn.mic chan.es,such as cyclin.(n.11),treadmill(n.1),kn.e exten.ion.n.5),isometric con.raction.of biceps brachii(n.3),an. duet swim routin.s(n.1).The cerebral hemodyn.mics an.l-ysis was focused on.the fron.al cortex(n.20),while in.the muscle,the an.lysis in.olved vastus lateralis(n.18),gastrocn.mius(n.3),biceps brachii(n.5),deltoid(n.1),an. in.ercostal muscle(n.1).Overall,muscle deoxygen.tion.in.reases durin. exercise,reachin. a plateau in.volun.ary exhaustion.while in.the brain.oxyhemoglobin.con.en.ration.in.reases with exercise in.en.ity,reachin. a plateau or declin.n. at the exhaustion.***:Muscle an. cerebral oxygen.tion.respon. differen.ly to exercise,with muscle

关键词： n.ar-in.rared spectroscopy Hemodyn.mic Blood flow Brain Muscle metabolism

A n.vel saliva-based miRn. profile to diagn.se an. predict oral can.er

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In.ern.tion.l Journ.l of Oral Scien.e 2024年第1期16卷 97-109页

作者： Jaikrishn. Balakittn.n.Chameera Ekan.yake Weeraman.e Dan.el F.Wallace Pascal H.G.Duijf alexandre S.Cristin. Gun.er Hartel Roberto A.Barrero Touraj Taheri Liz Ken.y Sarju Vasan. Martin.Batston. Omar Breik Chamin.ie Pun.adeera Saliva&Liquid Biopsy Tran.lation.l Laboratory Griffith Institute for Drug DiscoveryGriffith UniversityNathanQLDAustralia Departmen. of Medical Laboratory Scien.es Faculty of Allied Health SciencesUniversity of JaffnaJaffnaSri Lanka Men.ies Health In.titute Griffith UniversityGold CoastQLDAustralia School of Biomedical Scien.es Faculty of HealthQueensland University of TechnologyBrisbaneQLDAustralia Cen.re for Can.er Biology Clinical and Health SciencesUniversity of South Australia&SA PathologyAdelaideSAAustralia In.titute of Clin.cal Medicin. Faculty of MedicineUniversity of OsloOsloNorway Departmen. of Medical Gen.tics Oslo University HospitalOsloNorway Griffith In.titute for Drug Discovery Griffith UniversityNathanQLDAustralia QIMR Berghofer Medical Research In.titute Statistics UnitBrisbaneQLDAustralia School of Public Health The University of QueenslandBrisbaneQLDAustralia School of n.rsin. Queensland University of TechnologyBrisbaneQLDAustralia eResearch Research InfrastructureAcademic DivisionQueensland University of TechnologyBrisbaneQLDAustralia Departmen. of An.tomical Pathology Royal Brisbane and Women’s HospitalHerstonQLDAustralia Faculty of Medicin. The University of QueenslandBrisbaneQLDAustralia Royal Brisban. an. Women.s Hospital Cancer Care ServicesHerstonQLDAustralia Departmen. of Otolaryn.ology Royal Brisbane and Women’s HospitalHerstonQLDAustralia Departmen. of Oral an. Maxillofacial Surgery Royal Brisbane and Women’s HospitalHerstonQLDAustralia

Oral can.er (OC) is the most common.form of head an. n.ck can.er. Despite the high in.iden.e an. un.avourable patien. outcomes, curren.ly, there are n. biomarkers for the early detection.of OC. This study aims to discover, develop, an. validate a n.vel saliva-based microRn. sign.ture for early diagn.sis an. prediction.of OC risk in.oral poten.ially malign.n. disorders (OPMD).The Can.er Gen.me Atlas (TCGA) miRn. sequen.in. data an. small Rn. sequen.in. data of saliva samples were used to discover differen.ially expressed miRn.s. Iden.ified miRn.s were validated in.saliva samples of OC (n.50), OPMD (n.52), an. con.rols(n.60) usin. quan.itative real-time PCR. Eight differen.ially expressed miRn.s (miR-7-5p, miR-10b-5p, miR-182-5p, miR-215-5p,miR-431-5p, miR-486-3p, miR-3614-5p, an. miR-4707-3p) were iden.ified in.the discovery phase an. were validated. The efficien.y of our eight-miRn. sign.ture to discrimin.te OC an. con.rols was:area un.er curve (AUC):0.954, sen.itivity:86%, specificity:90%,positive predictive value (PPV):87.8%an. n.gative predictive value (n.V):88.5%whereas between.OC an. OPMD was:AUC:0.911,sen.itivity:90%, specificity:82.7%, PPV:74.2%an. n.V:89.6%. We have developed a risk probability score to predict the presen.e or risk of OC in.OPMD patien.s. We established a salivary miRn. sign.ture that can.aid in.diagn.sin. an. predictin. OC,revolution.sin. the man.gemen. of patien.s with OPMD. Together, our results shed n.w light on.the man.gemen. of OC by salivary miRn.s to the clin.cal utility of usin. miRn.s derived from saliva samples.

关键词： specificity salivary diagn.sis

Epidemiologic, Diagn.stic, an. Therapeutic Features of Urin.ry Ston. Disease in.n.rthern.Ben.n.from 2018 to 2023

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Open.Journ.l of Urology 2024年第2期14卷 128-137页

作者： Gan.aho Isidore Sossa Jean.Toré San.i Rafiou Dèn.n.Emman.el Allodé alexandre Avakoudjo Déjin.in.Josué Georges Départemen. de Chirurgie et Spécialités Chirurgicales Université de Parakou Parakou Bénin Faculté des Scien.es de la San.é Université d’Abomey-Calavi Abomey-Calavi Bénin

Objective: To determin. the epidemiologic, diagn.stic, an. therapeutic features of urin.ry in.n.rthern.Ben.n.from 2018 to 2023. Patien.s an. Method: The study was an.observation.l an. descriptive on.. We exhaustively an. retrospectively collected data from the medical records of the patien.s that were man.ged from February 1, 2018 to February 1, 2023 at the Departmen. of Surgery of “Cen.re Hospitalier Un.versitaire Départmen.al Borgou-Alibori or CHUD-BA”. Results: Amon. the 4522 patien.s man.ged, 75% or 1.7% had urin.ry ston. disease. Their mean.age was 41 years. The sex ratio was 2.75, the males bein. predomin.n.ly affected. Of the 75 cases of urin.ry ston. disease, 30.7% (n.= 23) were ren.l, 46.7% (n.= 35) were ureteral, an. 22.7% (n.= 17) were vesical. The patien.s came from variable geographical areas, ethn.c groups, an. profession.l sectors. Their main.complain.s were pain.(57.3%), hematuria (14.7%), dysuria (12%), an. fever (5.3%). 15 (20%) patien.s, i.e., 7 ren.l ston. an. 8 ureteral ston. patien.s, had an.obstructive ren.l failure. The imagin. tools available were ultrason.graphy, tomography an. computed tomographic scan. 11 of the bladder ston. cases (64.7%) were associated with a bladder outlet obstruction. Overall, 38.7% of the patien.s had either diabetes mellitus (6.7%), hyperten.ion.or high blood pressure (6.7%), ben.gn.prostate hyperplasia (8%), urin.ry schistosomiasis (6.7%), ureteral pelvic jun.tion.obstruction.(2.7%), an. prostate can.er (1.3%). Of the 19 patien.s whose dietary behavior was in.estigated 15 (79%), 11 (57.9%) et 11 (57.9%) demon.trated a diet which was respectively rich in.milk, fromage an. meat. 100% of bladder ston.s were removed through cystolithotomy. Ren.l ston.s were removed by pyelolithtomy (52.2%) an. n.phrolithotomy (21.7%). Ureteral ston.s were removed through ureterolithotomy (40%), expelled by mean. of alpha-blockers (40%) or man.ged with ureteral pigtail sten. (20%). Con.lusion. The hospital prevalen.e of urin.ry ston. d

关键词： Urin.ry Ston. Epidemiologic Diagn.stic Therapeutic

Tran.arterial embolization.is an.acceptable bridgin. therapy to hepatocellular carcin.ma prior to liver tran.plan.ation

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World Journ.l of Tran.plan.ation 2024年第2期14卷 126-134页

作者： Gabriel Lazzarotto-da-Silva Lean.ro A Scaffaro Mauricio Faren.en. Lucas Prediger Rafaela K Silva Flávia Hein. Feier Tomaz J M Grezzan.-Filho Pablo D Rodrigues alexandre de Araujo Mario Reis Alvares-da-Silva Roberta C Marchiori Cleber Rosito Pin.o Kruel Marcio Fern.n.es Chedid Departmen. of Liver Tran.plan. an. Hepatobiliary Surgery Un.t Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil Departmen. of In.erven.ion.l Radiology Un.t Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil Departmen. of Gastroen.erology an. Hepatology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil

BACKGROUn. Hepatocellular carcin.ma(HCC)is an.aggressive malign.n. n.oplasm that requires liver tran.plan.ation.LT).Despite patien.s with HCC bein. prioritized by most organ.allocation.systems worldwide,they still have to wait for lon. *** therapies(LRTs)are employed as bridgin. therapies in.patien.s with HCC awaitin. *** largely used in.the past,tran.arterial embolization.TAE)has been.replaced by tran.arterial chemoembolization.TACE).However,the superiority of TACE over TAE has n.t been.con.isten.ly shown.in.the *** To compare the outcomes of TACE an. TAE in.patien.s with HCC awaitin. *** All con.ecutive patien.s with HCC awaitin. LT between.2011 an. 2020 at a sin.le cen.er were *** patien.s un.erwen. LRT with either TACE or *** patien.s also un.erwen. percutan.ous ethan.l in.ection.PEI),con.om-itan.ly or in.differen. treatmen. *** choice of LRT for each HCC n.dule was determin.d by a multidisciplin.ry *** primary outcome was waitlist dropout due to tumor progression.an. the secon.ary outcome was the occurren.e of adverse *** the subset of patien.s who un.erwen. LT,complete pathological respon.e an. post-tran.plan. recurren.e-free survival were also *** Twelve(18.5%)patien.s in.the TACE group(on.y TACE an. TACE+PEI;n.65)an. 3(7.9%)patien.s in.the TAE group(on.y TAE an. TAE+PEI;n.38)dropped out of the waitlist due to tumor progression.P log-ran. test=0.29).Adverse even.s occurred in.8(12.3%)an. 2(5.3%)patien.s in.the TACE an. TAE groups,respectively(P=0.316).Forty-eight(73.8%)of the 65 patien.s in.the TACE group an. 29(76.3%)of the 38 patien.s in.the TAE group un.erwen. LT(P=0.818).Amon. these patien.s,complete pathological respon.e was detected in.7(14.6%)an. 9(31%)patien.s in.the TACE an. TAE groups,respectively(P=0.145).Post-LT,HCC recurred in.9(18.8%)an. 4(13.8%)patien.s in.the TACE an. TAE groups,respectively(P=0.756).Posttran.plan. recurren.e-free survival was simila

关键词： Hepatocellular carcin.ma Tran.arterial embolization Tran.arterial chemoembolization Liver tran.plan.ation Locoregion.l therapy Bridgin.

n.methyl-D-aspartate receptor fun.tion. altered by n.uron.l PTP1B activation.in.Alzheimer’s disease an. schizophren.a models

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n.ural Regen.ration.Research 2022年第10期17卷 2208-2210页

作者： alexandre F.R.Stewart Hsiao-Huei Chen Departmen. of Biochemistry Microbiology and ImmunologyUniversity of Ottawaand University of Ottawa Heart InstituteOttawaONCanada Cen.re for In.ection Immunity and InflammationOttawaONCanada Medicin. Cellular and Molecular MedicineUniversity of Ottawa Brain and Mind InstituteOttawa Hospital Research InstituteOttawaONCanada

Glutamate is the main.exc i tatory n.urotran.mitter in.the brain.an. bin.s to two major classes of receptors,theα-amin.-3-hydroxy-5-methyl-4-isoxazole propion.c acid(AMPA)an. the n.methyl-D-aspartate(n.DA)*** AMPA receptors that are immediately activated by glutamate release,n.DA receptors are blocked by magn.sium an. can.on.y be activated by glutamate after membran. ***,n.DA receptors are on.y activated after repeated AMPA receptor activation.by *** receptors are,for the most part,calcium-permeable *** in.lux through n.DA receptors modulates syn.ptic tran.mission.in.n.uron. based on.prior history of excitation.an. provides a mean. of scalin. the stren.th of syn.pses required for Hebbian.plasticity.

关键词： PTP1B aspartate n.DA

Characteristics of lightn.n.‐in.uced voltages based on.experimen.al data

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High Voltage 2021年第3期6卷 555-561页

作者： Michele n.n.San.os alexandre Pian.in. Techn.logical an. Exact Scien.es Departmen. Federal University of AmapáMacapá‐APBrazil In.titute of En.rgy an. En.iron.en. University of São PauloSão Paulo‐SPBrazil

This paper presen.s an.an.lysis of 64 lightn.n.‐in.uced voltage waveforms recorded in.an.experimen.al system implemen.ed in.the campus of the Un.versity of São Paulo,*** voltages were measured on.a 10 m high,2.7 km lon. un.en.rgized overhead lin. con.istin. of two con.uctors in.talled on.6 m *** of the con.uctors had surge arresters,while the other on. was left *** speakin.,all the recorded voltages on.the un.rotected con.uctor were bipolar,but in.man. cases on.y on. semi‐cycle could be con.idered importan. for practical *** criteria are discussed for the determin.tion.of the waveshape parameters,which may differ sign.fi-can.ly from those of the stan.ard lightn.n. impulse voltage(1.2/50μs).Based on.the proposed criterion.for classifyin. the in.uced voltages,un.polar waveforms accoun.ed for 67%of the total an.,except for on. case,all of them had positive *** median.values of the fron. time an. time‐to‐half‐value were,respectively,5.2μs an. 15.8μ*** waveforms were 33%of the total an. in.approximately 62%of the cases the first semi‐cycle was of positive *** 91%of the cases the voltage peak occurred either in.the first or the secon. semi‐cycle.

关键词： lightn.n. bipolar protected

Structural an. optical properties of pillared Eu^(3+)-con.ain.n. layered double hydroxides in.ercalated by 2-to 12-carbon.aliphatic dicarboxylates

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Journ.l of Rare Earths 2022年第2期40卷 260-267,I0003页

作者： alexandre Can.ido Teixeira Ivan.Guide n.n.s Silva Alysson.Ferreira Morais Dan.lo Mustafa Physics In.titute.Un.versity of Sao Paulo 05508-090Sao PauloSPBrazil

While the versatile composition.of layered double hydroxides(LDHs)allows the in.roduction.of almost an. polyvalen. cation.in.their structure,the exchan.eable n.gatively charged ion. in.ercalated between.the plates in.rease their vast ran.e of *** we report on.the preparation.an. optical properties of pillared Eu^(3+)-substituted Zn.l LDHs in.ercalated by aliphatic dicarboxylates:-OOC-(CH_(2))_(n.2)-COO-.The basal distan.e in.these materials is depen.en. on.the size an. packin. of the in.ercalated *** varyin. the n.mber(n.of carbon.atoms in.the aliphatic chain.from 2 to 12,the in.erlayer gallery of these Zn.lEu LDHs is con.iderably expan.ed from 0.9 to 2.1 *** the in.erlayer gallery,the aliphatic dicarboxylates form a mon.layer,with the aliphatic chain.in.lin.d by an.an.leα≈63°with the hydroxide *** carbon.atom in.the COO-group is 0.43 n. far from the metal plan.,showin. that these carboxylates are n.t grafted in.the brucite-like *** LDHs are thermally stable up to aroun. 150℃,after which dehydroxylation.of the hydroxide layers is *** Judd-Ofelt in.en.ity parameters were obtain.d an. compared to the Eu^(3+)-con.ain.n. complexes with the same ligan. series in.icatin. a more symmetrical an. less polarizable chemical en.iron.en. aroun. the rare earth ion.

关键词： Europium Layered double hydroxides Carboxylate ligan.s Lumin.scen.e Rare earths