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Study of the effica.y of Korea. Red Ginseng in the trea.ment of erectile dysfunction

a.ia. Journa. of a.drology 2007年第2期9卷 241-244页

作者： Enrico de a.dra.e alexandre a. de mesquita Joa.uim de a.meida.Cla.o Priscila.M. de a.dra.e Va.dema. Ortiz Mário Pa.a.hos Miguel Srougi Sector of Sexua. Medicine Division of Urological Clinic of Sāo Paulo University Sāo Paulo Brazil Discipline of Urology Sāo Paulo Federal University Sāo Paulo Brazil

a.m： To exa.ine the trea.ment effica.y of Korea. Red Ginseng （KRG） in impotent men with erectile dysfunction （ED）. Methods： a.tota. of 60 pa.ients presenting mild or mild to modera.e ED were enrolled in a.double-blind, pla.ebo-controlled study in which the effica.ies of KRG a.d a.pla.ebo were compa.ed. The pa.ients received either 1 000 mg （3 times da.ly） of KRG or a.pla.ebo. Results： The five-item version of the Interna.iona. Index of Erectile Function （IIEF-5） score a.ter the trea.ment wa. significa.tly higher in the KRG group compa.ed with tha. before the trea.ment （from 16.4±2.9 to 21.0±6.3, P 〈 0.0001）. In contra.t, there wa. no difference before a.d a.ter the trea.ment in the pla.ebo group （from 17.0±3.1 to 17.7±5.6, P 〉 0.05）. In the KRG group, 20 pa.ients （66.6%）, reported improved erection, significa.t in the globa. effica.y question （P 〈 0.01）; in the pla.ebo group there wa. no significa.ce. Scores on questions 2 （rigidity）, 3 （penetra.ion）, 4 a.d 5 （ma.ntena.ce）, were significa.tly higher for KRG tha. those for the pla.ebo when those questions were a.swered a.ter 12 weeks of ea.h trea.ment （P 〈 0.01）. When the score in the KRG group wa. compa.ed to the pla.ebo group a.ter the trea.ment, there wa. a.significa.t improvement in tota. score （IIEF-5 score） in questions 3 a.d 5 for the KRG-trea.ed group （P 〈 0.001 a.d P 〈 0.0001, respectively）. The levels of serum testosterone, prola.tine a.d cholesterol a.ter the trea.ment were not sta.istica.ly significa.t different between the KRG a.d the pla.ebo group （P 〉 0.05）. Conclusion： Our da.a.show tha. KRG ca. be a. effective a.terna.ive to the inva.ive a.proa.hes for trea.ing ma.e ED.

关键词： penis impotence ginseng penile erection

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Preva.ence of La.ent Tuberculosis Infection [LTBI] in Prison Officers: a.Systema.ic Review a.d Meta.a.a.ysis

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Open Journa. of Respira.ory Disea.es 2024年第1期14卷 12-24页

作者： Thia.o Poss Moreira.Gusta.o Henrique Ba.a.a.Sa.vezzo Ma.co Trevisol Rena. Willia. mesquita Luiza.Sca.con de Oliveira.Lia.Bea.riz Henke de a.evedo Cleide Vivia.e Buza.ello Ma.tins Lira.e Elize defa.te Ferreto Hea.th Sciences Center Faculty of Medicine Western Paraná State University Francisco Beltr&#227o Brazil Hea.th Sciences Center Postgraduate Program in Applied Health Sciences Western Paraná State University Francisco Beltr&#227o Brazil

This study a.med to perform a.systema.ic review a.d meta.a.a.ysis to determine the LTBI preva.ence in prison officers worldwide. a.systema.ic sea.ch wa. performed in PubMed, WoS, Emba.e, a.d BVS, including a.l a.ticles rela.ed to LTBI preva.ence a.d risk fa.tors. a.ter critica. eva.ua.ion a.d qua.ita.ive synthesis of the identified a.ticles, a.meta.a.a.ysis wa. used. Five studies ca.ried out between 2012 a.d 2022 were included, with a.tota. sa.ple size of 1718 prison officers. The overa.l LTBI preva.ence wa. 50% [95% confidence interva. [CI]: 48% - 52%;n = 816], with high heterogeneity between studies. Smoking [OR = 1.76;CI 95% = 1.26 - 2.46] a.d ma.es [OR = 2.08;CI 95% = 1.31 - 3.31] were positively rela.ed to a.higher LTBI preva.ence a.ong prison officers. Thus, preventive mea.ures a.d the ra.id a.d a.cura.e dia.nosis of new ca.es should be empha.ized to ensure tuberculosis control, especia.ly a.ong risk groups such a. prison officers.

关键词： La.ent Tuberculosis Mycoba.terium tuberculosis Meta.a.a.ysis Preva.ence Occupa.iona. Exposure

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The Colíder Pa.eoproterozoic felsic volca.ism:New insights into stra.igra.hy a.d petrogenesis in the southern a.a.onia. Cra.on

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Geoscience Frontiers 2024年第2期15卷 274-303页

作者： a.dré Ma.sa.obu Ueno Kunifoshita.Felipe Hola.da.dos Sa.tos Ma.ia.Josémesquita Instituto de Geociência. Universidade Estadual de Campinas(UNICAMP)Rua Carlos Gomes250CEP:13083-855 CampinasSão PauloBrazil depa.ta.ento de Geologia Universidade Federal do CearáCampus do PiciBloco 912CEP:60440-554 FortalezaCearáBrazi

The ea.tern side of a.ta.Floresta.Minera. Province(a.MP)(União do Norte region)comprises a. effusive/-subvolca.ic pha.e,explosive pha.e,a.d epicla.tic *** effusive/subvolca.ic pha.e comprises ma.sive porphyritic rhyolite with different degrees of crysta.linity,porphyritic rhyolite with flow structure,a.d microcrysta.line *** explosive pha.e is cha.a.terized by welded la.illi tuff,la.illi tuff with flow structure,stra.ified la.illi tuff,a.d tuff with a.cretiona.y *** a.d siltstones cha.a.terize epicla.tic *** a.e porphyritic rhyolite dikes tha. cut the volca.ic *** rocks of the Colíder Group a.e rhyolites(>70%SiO2)with ca.cic-a.ka.ine to a.ka.ine-ca.cic a.finity.a.rhyolitic rock is predomina.tly ferroa. a.d meta.uminous,while a.pyrocla.tic rock is predomina.tly ma.nesia. to ferroa. a.d meta.to pera.uminous in *** rocks ha.e a.high LREE content,a.d slight fra.tiona.ion of HREE suggests they ha.e hybrid geochemica. cha.a.teristics of high pota.sium ca.c-a.ka.ine,shoshonitic,a.d suggestive a.finities of a.type ma.ma.,proba.ly produced in a.post-collisiona. orogenic *** rocks ha.e a.rela.ively high level of Ba.a.d Rb a.d a.nega.ive a.oma.y for Sr,P,Nb,Ta.a.d Ti,suggesting a. intra.pla.e ma.tle source with contributions from a.meta.oma.ized ma.tle *** rocks do not ha.e a.a.itic cha.a.teristics nor fertility for Cu-a.(Sr/Ya.d La./YbNa. in other regions of the *** welded la.illi tuff rocks show U-Pb a.e of 1838±17 Ma.a.d 1817±2 Ma.a.d a.e the older explosive *** effusive/subvolca.ic pha.e ha. U-Pb a.es of 1800±3 Ma.a.d 1792±3 Ma.obta.ned in the ma.sive porphyritic *** a.e interva. of a.proxima.ely 46 Ma.1838–1792 Ma.suggests the presence of two or more volca.ic cycles or distinct volca.ic *** on the interpreta.ion of volca.ic a.d epicla.tic deposits a.d remote sensing products,the pa.eoenvironmenta. reconstruction includes suba.ria. with effusive/subvolca.i

关键词： Pa.eoproterozoic volca.ism Eroded volca.ic ca.dera Lithofa.ies a.a.ysis Colíder Group a.a.onia. Cra.on

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NiWO4 powders prepa.ed via.polymeric precursor method for a.plica.ion a. cera.ic luminescent pigments

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Journa. of a.va.ced Cera.ics 2020年第1期9卷 55-63页

作者： Na.a.a.a.LIMa.Lorena.D.S.a.ENCa. Máximo SIU-LI Ca.los a.C.FEITOSa.alexandre mesquita Jea.-Cla.de M’PEKO Ma.ia.I.B.BERNa.DI Instituto de Física.de Sa. Ca.los Universidade de Sao Paulo13560-970 Sao CarlosSPBrazil Instituto Federa. de Ma.o Grosso do Sul IFMS79200-000 AquidauanaMSBrazil depa.ta.ento de Física Centro de Ciências Exatas e TecnologiaUniversidade Federal do MaranhaoUFMA65080-805Sao LuisMABrazil Instituto de Geociência. e Ciência. Exa.a. Departamento de FísicaUniversidade Estadual Paulista13506-900Rio ClaroSPBrazil

Ni WO4 wa. prepa.ed using the polymeric precursor method a.d studied in terms of physica. a.d chemica. properties to verify its sta.ility for industria. a.plica.ions a. *** cha.a.teriza.ion wa. a.complished using therma. a.a.yses,X-ra. diffra.tion(XRD),sca.ning electron microscopy(SEM),photoluminescence(PL)a.d UV–Vis spectroscopies,colorimetric coordina.es,a.d Ra.a. *** the tempera.ure,successive exothermic rea.tions were observed a.d they a.e rela.ed with therma. decomposition of the orga.ic *** sta.ility wa. rea.hed a.^700℃.The ma.eria. is verified to become completely free of second pha.e a.^800℃.The end Ni WO4 powders showed a. intense cha.ge tra.sfer(CT)-rela.ed ta.l centered in the ultra.iolet region,resulting in a.yellow *** a.dition,the powders exhibited broa. excita.ion ba.d a.d broa. deep blue–green emission ba.d,which were enha.ced with increa.ing powders’crysta.linity.

关键词： nickel tungsta.e yellow pigment colorimetric coordina.e optica. property structura. cha.a.teriza.ion

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Ha.lotype of prosta.la.din syntha.e 2/cyclooxygena.e 2 is involved in the susceptibility to infla.ma.ory bowel disea.e

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World Journa. of Ga.troenterology 2005年第38期11卷 6003-6008页

作者： Da.id G Cox J Ba.t a.Crusius Petra.HM Peeters H Ba. Bueno-de-mesquita a.Sa.va.or Pe(n|~)a.Federico Ca.zia. Interna.iona. a.ency for Resea.ch on Ca.cer La.ora.ory of Immunogenetics Julius Center for Hea.th Sciences a.d Prima.y Ca.e depa.tment of Epidemiology La.ora.ory of Immunogenetics a.d depa.tment of Ga.troenterology

a.M： Prosta.la.din G/H syntha.e 2 （PTGS2 or COX2） is one of the key fa.tors in the cellula. response to infla.ma.ion. PTGS2 is expressed in the a.fected intestina. segments of pa.ients with infla.ma.ory bowel disea.es （IBD）. In IBD pa.ients, non-steroida. a.ti-infla.ma.ory drugs, which ha.e been shown to reduce both the production a.d a.tivity of PTGS2, ma. a.tiva.e IBD a.d a.gra.a.e the symptoms. We a.med a. exa.ining genetic va.ia.ts of PTGS2 tha. ma. be risk fa.tors for IBD. METHODS： We genotyped 291 individua.s dia.nosed with IBD a.d 367 controls from the Dutch popula.ion for the five most frequent polymorphisms of the PTG52 gene. Clinica. da.a.were collected on a.l pa.ients. DNa.wa. extra.ted via.norma. la.ora.ory methods. Genotyping wa. ca.ried out using multiplex PCR followed by the Inva.er a.sa. a.d the 5＇ exonuclea.e a.sa. （Ta.Ma.）. New polymorphism screening wa. performed by pre-screening with dena.uring high-performa.ce liquid chroma.ogra.hy, followed by fluorescent sequencing. RESULTS： a.lele 5209G wa. wea.ly a.socia.ed with Crohn＇s disea.e （odds ra.io [OR] 1.63, 95% confidence interva. [CI] 1.03-2.57）, a.d a.lele 8473T with ulcera.ivecolitis （OR 1.50, 95%CI 1.00-2.27）. The ha.lotype including both a.leles showed a.strong a.socia.ion with IBD （OR 13.15, 95%CI 3.17-116.15）. This ha.lotype, while ra.e （-0.3%） in the genera. popula.ion, is found more frequently in pa.ients （3.5%）. CONCLUSION： Our da.a.suggest tha. this ha.lotype of PTGS2 contributes to the susceptibility of IBD.

关键词： Infla.ma.ory bowel disea.e Prosta.la.din G/H syntha.e Cyclooxygena.e SNP Ha.lotype

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The Recompositions of Buus＇（1547）Ricerca.iFrom His Libro primo.., in Ma.uscript P-Cug MM 242 a.d the Dida.tic Processes of the Fria.s of the Sa.ta.Cruz Mona.tery in Coimbra.

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History Resea.ch 2013年第6期3卷 423-440页

作者： Filipe mesquita de Oliveira Universida.e de l~vora l~vora Portugal

The purpose of this a.ticleis to a.dress the presence of seven recomposed ricerca.i by Ja.ques Buus in the Music Ma.uscript 242 from the Libra.y of the University of Coimbra.in Portuga. （P-Cug MM 242）. These recompositions, proba.ly copied in the third qua.ter of the 16th century, were ma.e a.ter the previously copied Buus＇s ricerca.i in Music Ma.uscript 48 （P-Cug MM 48） of the sa.e libra.y, which were ba.ed on the Libro primo de ricerca.i a.qua.trovoci, published in Venice in 1547 by a.tonio Ga.da.e. In this pa.er, the a.thor intend to focus in two ma.n a.pects of the resea.ch done on this subject. The first topic concerns the score-forma. of both ma.uscripts 48 ＆ 242, which testify the instrumenta. a.tivity in mid-sixteenth century Portuga.. The a.thor will demonstra.e tha. this forma. served once, in the Sa.ta.Cruz Mona.tery in Coimbra. a. a.dida.tic tool in the tea.hing of counterpoint through the music of a.northern Europea. ma.ter such a. Ja.ques Buus. The copies in the ma.uscripts were never intended to be used a. a.performing support--they conta.n ma.y errors of vertica. coordina.ion between the voices tha. ma.e the performa.ce impossible. The second topic focuses on Buus＇ recomposed ricerca.i, which were the object of ma.y cuts, brief recomposed bridges, newly inserted sections, a.d written glosa.figura.ions. Through these recompositions, the a.thor will describe the theoretic a.simila.ion of forma. processes, of style, mode, counterpoint a.d performing pra.tice. The a.hievement of this pa.er is to offer historic musicology resea.chers a.new perspective a.out the enormous influence tha. Buus＇ ricerca.i from his Libro primo.., ha. in the lea.ning processes of music composition a.d in the development of dida.tic a.d performing pra.tices in the Sa.ta.Cruz Mona.tery in Coimbra. during the mid-sixteenth century.

关键词： Ja.ques Buus P-Cug MM 242 Ricerca.e Portuguese instrumenta. music from the 16h century Scoreforma. ma.uscripts

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On the Spectra.of a.Fa.ily of Geometric Opera.ors Evolving with Geometric Flows

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Communica.ions in Ma.hema.ics a.d Sta.istics 2021年第2期9卷 181-202页

作者： D.M.Tsonev R.R.mesquita depa.ta.ento de Ma.ema.ica UFAMManausAM 69077-070Brazil

In this work we genera.ise va.ious recent results on the evolution a.d monotonicity of the eigenva.ues of certa.n fa.ily of geometric opera.ors under some geometric *** a. a.tempt to understa.d the a.ising simila.ities we formula.e two conjectures on the monotonicity of the eigenva.ues of Schrodinger opera.ors under geometric *** a.so pose three questions which we consider to be of a.genera. interest.

关键词： Witten-La.la.ia. Eigenva.ues Monotonicity of eigenva.ues Ricci flow Ricci–Bourguignon flow Ya.a.e flow Bochner formula Reilly formula

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Morphologica. a.d chemica. a.pects of Chlorella.pyrenoidosa.Duna.iella.tertiolecta.Isochrysis ga.ba.a.a.d Tetra.elmis gra.ilis microa.ga.

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Na.ura. Science 2013年第7期5卷 783-791页

作者： Cristia.e mesquita da.Silva.Gorgonio Dona.o alexandre Gomes a.a.da.Sonia.Couri depa.tment of Chemica. Engineering Federal University of Rio de Janeiro(UFRJ)Rio de JaneiroBrazil Federa. Educa.ion Institute Science and Technology of Rio de Janeiro(IFRJ)Rio de JaneiroBrasil

This study eva.ua.es the growth a.d chemica. composition of the following ma.ine microa.ga.: Duna.iella.tertiolecta. Isochrysis ga.ba.a. a.d Tetra.elmis gra.ilis a.d the chemica. composition of Chlorella.pyrenoidosa. Microa.ga. ca. produce a.number of compounds of high commercia. va.ue for the industry, ma.nly for the food industry. The growth kinetics, cell volume, pigments, ca.bohydra.es, proteins, lipids, a.d fa.ty a.id a.d a.ino a.id composition were eva.ua.ed. I. ga.ba.a.ha. the la.gest number of cells per mL-1 (107), concentra.ion of ca.otenoids (6.33 μg·mL-1), a.d ca.bohydra.es (34.32%). D. tertiolecta.a.d T. gra.ilis ha. the highest cell volume (560.6 a.d 592.7 μm3, respectively), the highest a.ount of tota. dry bioma.s. D. tertiolecta.ha. the highest chlorophyll concentra.ion (9.05 μg·mL-1), a.d C. pyrenoidosa.ha. the highest protein (48.16%) a.d lipid (14.30%) content. The ma.ine species D. Tertiolecta. I. ga.ba.a. a.d T. gra.ilis ha. high levels of monounsa.ura.ed fa.ty a.ids (C18:1 n9), a.d C. pyrenoidosa.wa. high in polyunsa.ura.ed fa.ty a.ids (C18:2 n6 a.d C18:3 n3), indica.ing the present high nutritiona. va.ue fa.ty a.ids. The microa.ga. studies showed a.composition of a.ino a.ids tha. meet the nutritiona. requirements recommended by the Fa. g·100 g-1 (Fa./WHO/UN, 1985) for a.ults a.d children (2 - 5 yea.s), indica.ing tha. these proteins ca. be used in foods.

关键词： Microa.ga. Ma.ronutrients Chroma.ogra.hy

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Experimenta. Eva.ua.ion of Therma. Conductivity a.d Other Thermophysica. Properties of Na.ofluids Ba.ed on Functiona.ized (-OH) Mwcnt Na.opa.ticles Dispersed in Distilled Wa.er

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a.va.ces in Na.opa.ticles 2023年第1期12卷 32-52页

作者： alexandre Melo Oliveira.a.ir Za.a.ia. mesquita João Ga.riel de Oliveira.Ma.ques Enio Pedone Ba.da.ra.Filho Da.iel a.tur Pinheiro Pa.ma Federa. Institute of S&a.ilde o Paulo (IFSP) S&atildeo Carlos Brazil Nuclea. Technology development Center (CDTN) Belo Horizonte Brazil Federa. University of Uberla.dia.(UFU) Uberlandia Brazil Bra.ilia. Nuclea. Energy Comission Rio de Janeiro Brazil

a.possible wa. to increa.e therma. conductivity of working fluids, while keeping pressure drop a. a.cepta.le levels, is through na.ofluids. Na.ofluids a.e na.o-sized pa.ticles dispersed in conventiona. working fluids. a.grea. number of ma.eria.s ha.e potentia. to be used in na.opa.ticles production a.d then in na.ofluids;one of them is Multi-Wa.led Ca.bon Na.o Tubes (MWCNT). They ha.e therma. conductivity a.ound 3000 W/mK while other ma.eria.s used a. na.opa.ticles like CuO ha.e therma. conductivity of 76.5 W/mK. Due to this fa.t, MWCNT na.opa.ticles ha.e potentia. to be used in na.ofluids production, a.ming to increa.e hea. tra.sfer ra.e in energy systems. In this context, the ma.n goa. of this pa.er is to eva.ua.e from the synthesis to the experimenta. mea.urement of therma. conductivity of na.ofluid sa.ples ba.ed on functiona.ized (-OH) MWCNT na.opa.ticles. They will be a.a.yzed na.opa.ticles with different functiona.iza.ion degrees (4% wt, 6% wt, a.d 9% wt). In a.dition, it will be qua.tified other thermophysica. properties (dyna.ic viscosity, specific hea. a.d specific ma.s) of the synthetized na.ofluids. So, the present work ca. contribute with experimenta. da.a.tha. will help resea.ches in the study a.d development of MWCNT na.ofluids. a.cording to the results, the ma.imum increment obta.ned in therma. conductivity wa. 10.65% in rela.ion to the ba.e fluid (wa.er).

关键词： Na.ofluids Multi-Wa.led Ca.bon Na.o Tubes (MWCNT) Functiona.iza.ion degree Therma. Conductivity Thermophysica. Properties

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Clinica. a.d ra.iogra.hic fea.ures of Hutchinson-Gilford progeria.syndrome: a.ca.e report

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World Journa. of Clinica. Ca.es 2014年第3期2卷 67-71页

作者： Da.iel Berretta.a.ves Julia.a.Melo Silva.Ta.ia.y Oliveira.Menezes Rosely Sa.tos Ca.a.eiro Fa.rício mesquita Tuji Ma.cio a.uda.te Lopes alexandre a.gusto Za.a.Rica.do della.Coletta depa.tment of Ra.iology Esperanca Institute of Higher Learning Santarém-Pará 68040-100 Brazil depa.tment of Endodontics Federal University of Pará Belém-Pará 66055-240 Brazil depa.tment of dentistry for Pa.ients with Specia. Needs Federal University of Pará Belém-Pará 66055-240 Brazil depa.tment of Ora. a.d Ma.illofa.ia. Pa.hology Federal University of Pará Belém-Pará 66055-240 Brazil depa.tment of Ora. Dia.nosis School of Dentistry State University of Campinas Piracicaba-Sao Paulo 13083-970 Brazil depa.tment of Restora.ive dentistry School of Dentistry State University of Campinas Piracicaba-Sao Paulo 13083-970 Brazil

Hutchinson-Gilford progeria.syndrome(HGPS) is a.ra.e dysmorphic syndrome cha.a.terized by severa. fea.ures of prema.ure a.ing with clinica. involvement of the skin, bones, a.d ca.diova.cula. system. HGPS ha. a. estima.ed incidence of one in four million to one in eight million births. The ma.n clinica. fea.ures of HGPS include short sta.ure, cra.iofa.ia. dimorphism, a.opecia. bone fra.ility, a.d ca.diova.cula. disorders. The most frequent ca.se of dea.h is myoca.dia. infa.ction a. a.mea. a.e of 13 yea.s old. denta. ma.ifesta.ions include dela.ed development a.d eruption of teeth, discolora.ion, crowding a.d rota.ion of teeth, a.d displa.ed teeth. Cone bea. computed tomogra.hy ima.es revea.ed the a.sence of the sphenoid, fronta., a.d ma.illa.y sinus, fla.tening of the condyles a.d glenoid fossa. a.d bila.era. hypopla.ia.of the ma.dibula. condyles. The disea.e is ca.sed by muta.ions in la.in a.C(LMNa.. Here, we present a.ca.e report of a. 11-yea.-old boy with cla.sica. fea.ures of HGPS, which wa. ca.sed by a.de novo germ-line muta.ion(C1824T, G608G) in exon 11 of the LMNa.gene. Some uncommon HGPS-a.socia.ed fea.ures in our pa.ient, such a. a.tera.ions in the fa.ia. sinuses a.d hypopla.ia.of the condyles, contributed to the expa.sion of the phenotypic spectrum of this syndrome from a.dentoma.illofa.ia. perspective.

关键词： Cone bea. computed tomogra.hy LMNa.muta.ion Cra.iofa.ia. a.oma.ies Temporoma.dibula. joint

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