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Effects of grassland management, endophytic fungi and predators on aphid abundance in two distinct regions

Journal of Plant Ecology 2014年第5期7卷 490-498页

作者： Carmen Börschig alexandra-M.Klein Jochen Krauss Agroecology Department of Crop SciencesUniversity of GöttingenGrisebachstrasse 6D-37075 GöttingenGermany Ecosystem Functions Institute of EcologyUniversity of LüneburgScharnhorstrasse 1D-21335 LüneburgGermany Nature Conservation and Landscape Ecology Institute of Earth and Environmental SciencesUniversity of FreiburgTennenbacherstr.4D-79106 FreiburgGermany Department of Animal Ecology and Tropical Biology University of WürzburgBiocentreAm HublandD-97074 WürzburgGermany

Aims Fungal endophytes of cool-season grass species produce alkaloids toxic to herbivores,affecting food webs in agricultural and natural *** studies about the effects of endophytes on herbi-vores are rare and show contradictory results,leading to uncertain conclusions about the nature of endophyte-grass *** asked whether the environmental contexts of local and regional scales and predation could modify the effects of endophytes on *** In a full factorial field experiment,we quantified the abundance of the aphid species Rhopalosiphum padi on the potted host grass Lolium perenne,which was either infected or uninfected with the endophytic fungus Neotyphodium *** were either excluded or had free access to the pots with the *** hun-dred and sixty grass pots were located in two regions on altogether 40 grassland sites,half of the sites intensively and half extensively *** tested the importance of endophyte infection,study region,management intensity of grasslands,predation and all two-way interactions on aphid *** Findings Endophyte infection reduced aphid abundance significantly in one study region *** both regions,we found that the impacts of aphidophagous predators and grassland management intensity on aphid abundance were substantially stronger and more consistent than that of endophytes on aphid *** excluding preda-tors and pots placed on extensive grasslands contained higher aphid *** impact of predators and management on aphid abundance were not modified by the *** conclude that the effect of endophytes on herbivores can be weak in field experi-ments and depends on environmental context at a regional ***,more field research efforts are necessary to detect the rela-tive importance of endophytes and the environmental context on biotic interactions in ecosystems.

关键词： bottom-up control microorganism multi-trophic interaction predator exclosure top-down control

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Artificial intelligence as a noninvasive tool for pancreatic cancer prediction and diagnosis

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World Journal of Gastroenterology 2023年第12期29卷 1811-1823页

作者： alexandra Corina Faur Daniela Cornelia Lazar Laura Andreea Ghenciu Department of Anatomy and Embriology “Victor Babeș”University of Medicine and Pharmacy TimișoaraTimișoara 300041TimișRomania Department V of Internal Medicine I Discipline of Internal Medicine IVUniversity of Medicine and Pharmacy“Victor Babes”TimișoaraTimișoara 300041TimișRomania DepartmentⅢ Discipline of Pathophysiology“Victor Babeș”University of Medicine and PharmacyTimișoara 300041TimișRomania

Pancreatic cancer(PC)has a low incidence rate but a high mortality,with patients often in the advanced stage of the disease at the time of the first *** detected,early neoplastic lesions are ideal for surgery,offering the best *** lesions of the pancreas include pancreatic intraepithelial neoplasia and mucinous cystic neoplasms,with intraductal papillary mucinous neoplasms being the most commonly *** study focused on predicting PC by identifying early signs using noninvasive techniques and artificial intelligence(AI).A systematic English literature search was conducted on the PubMed electronic database and other *** obtained a total of 97 studies on the subject of pancreatic *** final number of articles included in our study was 44,34 of which focused on the use of AI algorithms in the early diagnosis and prediction of pancreatic *** algorithms can facilitate diagnosis by analyzing massive amounts of data in a short period of *** can be made through AI algorithms by expanding image and electronic medical records databases,which can later be used as part of a screening program for the general ***-based screening models should involve a combination of biomarkers and medical and imaging data from different *** requires large numbers of resources,collaboration between medical practitioners,and investment in medical infrastructures.

关键词： Pancreatic cancer Early pancreatic lesions Pancreatic neoplasia Artificial intelligence Deep learning Machine learning Radiomics Diagnosis Pancreas

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The Impact of Psychosocial Influences on Chronic Wound Healing

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Open Journal of Medical Psychology（医学心理学） 2024年第3期 39页

作者： Kelly Frasier Vivian Li Sara Christoforides Kathleen Daly alexandra Loperfito Karina Stech Milena Dragovic

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Successful Luxury Branding in the Chinese Context

Successful Luxury Branding in the Chinese Context

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作者： alexandra Mary Mathou 复旦大学

学位级别：硕士

奢侈品品牌传播在过去要容易得多。商业活动因限于一国之内而减少了竞争,也正因此,消费者对品牌忠诚,并且易于划分。不过,这一切现在都改变了。奢侈品品牌面临高度竞争的国际化市场和眼光挑剔的顾客,他们对享乐与创造性有着独特的品味,... 详细信息

奢侈品品牌传播在过去要容易得多。商业活动因限于一国之内而减少了竞争,也正因此,消费者对品牌忠诚,并且易于划分。不过,这一切现在都改变了。奢侈品品牌面临高度竞争的国际化市场和眼光挑剔的顾客,他们对享乐与创造性有着独特的品味,这一点在中国尤其如此。中国市场对奢侈品品牌是不同寻常的。呈现在中国市场上的奢侈品多数是西方的品牌,因此必须设法将奢侈品的品牌认同与中国消费者的预期进行融合。这一点对于奢侈品品牌无异于一个巨大的挑战,因为中国消费者和中国的商业版图在1991年经济改革后的近三十年中已经发生了巨大变化。除此之外,应对当前严峻的经济状况、受政治影响深远的媒体环境以及执政党新的政策都是奢侈品品牌当下需要面对的问题。以上的问题带来明显的挑战,即品牌不得不在本土消费者需求与国际化间寻求一个平衡。此外,持续推陈出新与保持品牌固有的传统也是一对不得不权衡的矛盾。这些问题都令建构一个恰当的品牌认同变得复杂,本文旨在回答奢侈品品牌在维持品牌认同与拓展中国市场过程中所面临的问题。一系列采访用于评估当前中国市场的奢侈品状况,品牌营销状况,中国市场成功的品牌案例,以及中国未来奢侈品市场的预测。收集的数据采用了量化分析的方式。基于数据分析得出结论,奢侈品品牌侧重于品牌认同的部分侧面进行传播,例如传承。不过他们更倾向于向中国消费者传达能够产生联系,并对他们有足够吸引力的部分。不过由于数字时代的来临,在过去看起来行之有效的品牌营销方式在今天却可能拖后腿。同时,他们也采用不同的方式表现得独特,以达到吸引消费者和打击竞争对手的目的。尽管品牌力求独特,不过一些通用法则仍然被采用,例如让消费者产生梦想的联想。当前造成进退两难的原因主要在于对品牌传统的坚持与创新性与现代性的需求。奢侈品牌的成功最终取决于公众的认知与品牌形象,而这恰恰是品牌自身所无法左右的。不过只有通过有效的传播,品牌认同与品牌形象之间的割裂局面能够得到有效弥合。

关键词：奢侈品品牌化中国语境

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Islam and Islamic Terrorism;The Role of Religious Ideologies in Radicalizing the Middle East

Islam and Islamic Terrorism;The Role of Religious Ideologies...

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作者： Myrna alexandra Atyah 山东大学

学位级别：硕士

This paper studies the relation between Islam as a religion and ideology on the one hand,and Islamic terrorism and the radicalization of the Middle East on the other *** purpose of this study is to examine the motivation and justification of Islamic terrorism which are provided by the Islamic terrorists themselves through their religious scripture and ideological texts and ***,the research expands to examine the role of that specific religious ideology in shaping the main common features,patterns,and characteristics of the majority of Islamic terrorist groups and *** research utilizes qualitative and quantitative methods to analyze relevant data from various fields and *** study of terrorism is an interdisciplinary one that benefits from the literature and research traditions in politics,sociology,psychology,philosophy,and religious studies amongst many other ***,my research attempts to engage in the basic discourse in those fields in a limited manner that focuses narrowly on the connection between the Islamic doctrine and Islamic terrorism within the geographical borders of the Middle East *** paper benefits from the analysis and evaluation of qualitative and quantitative data acquired from religious,historical,political,and sociological sources which enjoy a great deal of authenticity and credibility.

关键词： Terrorism Islamic terrorism Islamic doctrine Istamic Sharia Radicalization The Middle East Insecurity in The Middle East History of terrorism

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Pancreatic cancer: Are 'liquid biopsies' ready for prime-time?

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World Journal of Gastroenterology 2016年第32期22卷 7175-7185页

作者： alexandra R Lewis Juan W Valle Mairead G Mc Namara The Christie NHS Foundation Trust M20 4BX ManchesterUnited Kingdom Institute of Cancer Sciences University of ManchesterM20 4BX ManchesterUnited Kingdom

Pancreatic cancer is a disease that carries a poor prognosis. Accurate tissue diagnosis is required. Tumours contain a high content of stromal tissue and therefore biopsies may be inconclusive. Circulating tumour cells(CTCs) have been investigated as a potential "liquid biopsy" in several malignancies and have proven to be of prognostic value in breast, prostate and colorectal cancers. They have been detected in patients with localised and metastatic pancreatic cancer with sensitivities ranging from 38%-100% using a variety of platforms. Circulating tumour DNA(ct DNA) has also been detected in pancreas cancer with a sensitivity ranging from 26%-100% in studies across different platforms and using different genetic markers. However, there is no clear consensus on which platform is the most effective for detection, nor which genetic markers are the most useful to use. Potential roles of liquid biopsies include diagnosis, screening, guiding therapies and prognosis. The presence of CTCs or ct DNA has been shown to be of prognostic value both at diagnosis and after treatment in patients with pancreatic cancer. However, more prospective studies are required before this promising technology is ready for adoption into routine clinical practice.

关键词： Pancreatic Cancer Liquid biopsy Circulating Tumour Cells Circulating Tumour DNA

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Monitoring and Prediction of Indoor Air Quality for Enhanced Occupational Health

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Intelligent Automation & Soft Computing 2023年第1期35卷 925-940页

作者： Adela POP(Puscasiu) alexandra Fanca Dan Ioan Gota Honoriu Valean Technical University of Cluj Napoca Cluj NapocaRomania

The amount of moisture in the air is represented by relative humidity(RH);an ideal level of humidity in the interior environment is between 40%and 60%at temperatures between 18°and 20°*** the RH falls below this level,the environment becomes dry,which can cause skin dryness,irritation,and discomfort at low *** the humidity level rises above 60%,a wet atmosphere develops,which encourages the growth of mold and *** and allergy symptoms may occur as a *** health is harmed by excessive humidity or a lack *** can be used to provide an optimal level of humidity and a stable and pleasant atmosphere;certain models disinfect and purify the water,reducing the spread of *** design and implementation of a client-server indoor and outdoor air quality monitoring application are presented in this *** Netatmo station was used to acquire the data needed in the *** client is an Android application that allows the user to monitor air quality over a period of their *** a good monitoring process,the Netatmo modules were used to collect data from both environments(indoor:temperature(T),RH,carbon dioxide(CO_(2)),atmospheric pressure(Pa),noise and outdoor:T and RH).The data is stored in a database,using *** Android application allows the user to view the evolution of the measured parameters in the form of ***,the paper presents a prediction model of RH using Azure Machine Learning Studio(Azure ML Studio).The model is evaluated using metrics:Mean Absolute Error(MAE),Root Mean Squared Error(RMSE),Relative Absolute Error(RAE),Relative Squared Error(RSE)and Coefficient of Determination(CoD).

关键词： Machine learning indoor air quality humidity carbon dioxide relative humidity

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Ultrafiltration for environmental safety in shellfish production: A case of bloom emergence

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Water Science and Engineering 2021年第1期14卷 46-53页

作者： Clemence Cordier alexandra Voulgaris Christophe Stavrakakis Patrick Sauvade Franz Coelho Philippe Moulin Aix-Marseille Universite M2P2 UMR 7340Equipe Procedes MembranairesLaboratoire de Mecanique Modelisation et Procedes PropresAix en Provence 13545France Plateforme Experimentale Mollusques Marins Station Ifremer de BouinPolder des ChampsBouin 85230France Suez-Aquasource Toulouse 31029France

The process of ultrafiltration(UF)of natural seawater often encounters the problems of variation in water quality and coastal *** validate the feasibility of UF in shellfish farms,this study compared the hydraulic performance and pollutant removal efficiency of the UF process with those of the commonly used treatments that combine several filtration steps with ultraviolet(UV)*** comparison was conducted in the cases of natural seawater and a coastal *** that the UF process encountered the specific type of pollution,this study evaluated the filtration performance of the UF process and the retention of total suspended solids(TSS),bacteria,phytoplankton,and zooplankton.A real coastal bloom was considered in the case study of an experimental shellfish hatchery/nursery in *** results show that both treatments were able to eliminate approximately 50%of ***,in contrast with UV treatment combined with filtration,the UF process retained total amounts of phytoplankton,zooplankton,and bacteria in the *** the hydraulic performance of the UF process was impacted by the coastal bloom,the fouling was eliminated through chemical cleaning conducted at a frequency less than once per 12 *** the severe pollution,this study confirmed the pollution resistance and treatment performance of the UF process,indicating that UF has the potential to enhance the biosecurity level.

关键词： Ultrafiltration Environmental safety Aquaculture Shellfish culture Coastal bloom

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Acute hepatitis of unknown etiology in an adult female:A case report

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World Journal of Clinical Cases 2023年第22期11卷 5288-5295页

作者： Lucinda Dass alexandra Marie Malabanan Pacia Mahgol Hamidi Department of Clinical Studies St.George's UniversityTrue Blue 00000Grenada Department of Internal Medicine Jersey City Medical CenterJersey CityNew Jersey 07307United States

BACKGROUND Acute liver injury(ALI)refers to inflammation of the hepatic parenchyma without hepatic encephalopathy that lasts less than 6 *** the etiology is unknown,Acute Hepatitis of Unknown Origin(AHUO)can present as a diagnostic and treatment *** in the adult population is unusual and poorly *** has an incidence between 11%and 75%.Currently,no treatment guidelines *** no identified cause,treatment is often blind,and the wrong treatment plan may have unintended *** SUMMARY We present the case of a 58-year-old woman who presented to the emergency room for elevated liver function tests(LFTs).Her symptoms started 10 d prior to admission and included nausea,vomiting,jaundice,decreased appetite,weight loss of 10 lbs,and dark *** denied drinking alcohol or taking any hepatotoxic agents,including acetaminophen,statins,vitamins,or *** was admitted to the hospital,and an etiologic work-up was carried *** initial bloodwork revealed elevated liver enzymes(alanine aminotransferase 2500 U/L,aspartate aminotransferase 3159 U/L,and alkaline phosphatase 714 U/L)and elevated total bilirubin of 6.4 mg/*** tested negative for common infectious etiologies such as hepatotropic viruses A,B,C,and *** infective work-up revealed negative serology for cytomegalovirus,Epstein-Barr virus,herpes simplex virus 1&2,and human immunodeficiency *** autoanti-body test results were negative,including anti-smooth muscle antibody,anti-mitochondrial antibody,and anti-liver kidney microsome 1 *** resonance cholangiopancreatography ruled out biliary causes of elevated LFTs,and her core liver biopsy proved *** the course of her hospital stay,the patient's LFTs improved with supportive care and without *** Idiopathic hepatitis makes treatment *** can leave patients feeling confused and ***,educating the patient thoroughly for shared decision-making and manag

关键词： Acute hepatitis Acute liver injury Idiopathic hepatitis Acute hepatitis of unknown etiology Case report

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MicroRNA-155 mediates endogenous angiotensin II type 1 receptor regulation:implications for innovative type 2 diabetes mellitus management

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世界糖尿病杂志:英文版(电子版) 2023年第9期14卷 1334-1340页

作者： Konstantinos I Papadopoulos alexandra Papadopoulou Tar-Choon Aw Department of R&D THAI StemLifeBangkok 10310Thailand Occupational and Environmental Health Services Feelgood LundLund 223-63SkåneSweden Department of Laboratory Medicine Changi General HospitalSingapore 529889SingaporeSingapore Department of Medicine National University of SingaporeSingapore 119228SingaporeSingapore

Type 2 diabetes mellitus(T2DM)is a lifelong condition and a threat to human *** understanding of its pathogenesis is acutely needed in order to devise innovative,preventative,and potentially curative pharmacological ***(miRNA),are small,non-coding,one-stranded RNA molecules,that can target and silence around 60%of all human genes through translational ***-155 is an ancient,evolutionarily well-conserved miRNA,with distinct expression profiles and multifunctionality,and a target repertoire of over 241 genes involved in numerous physiological and pathological processes including hematopoietic lineage differentiation,immunity,inflammation,viral infections,cancer,cardiovascular conditions,and particularly diabetes ***-155 Levels are progressively reduced in aging,obesity,sarcopenia,and ***,the loss of coordinated repression of multiple miR-155 targets acting as negative regulators,such as C/EBPβ,HDAC4,and SOCS1 impacts insulin signaling,deteriorating glucose homeostasis,and causing insulin resistance(IR).Moreover,deranged regulation of the renin angiotensin aldosterone system(RAAS)through loss of Angiotensin II Type 1 receptor downregulation,and negated repression of ETS-1,results in unopposed detrimental Angiotensin II effects,further promoting ***,loss of BACH1 and SOCS1 repression abolishes cytoprotective,anti-oxidant,anti-apoptotic,and anti-inflam matory cellular pathways,and promotesβ-cell *** contrast to RAAS inhibitor treatments that further decrease already reduced miR-155 Levels,strategies to increase an ailing miR-155 production in T2DM,e.g.,the use of metformin,mineralocorticoid receptor blockers(spironolactone,eplerenone,finerenone),and verapamil,alone or in various combinations,represent current treatment *** the future,direct tissue delivery of miRNA analogs is likely.

关键词： Angiotensin II Angiotensin II type 1 receptor Arginase 2 L-type calcium channel Mineralocorticoid receptor MiRNA-155 Renin-angiotensin aldosterone system Type 1/2 diabetes mellitus Verapamil

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