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Journal of Safety Science and Resilience 2022年第1期3卷 87-91页

作者： Tobias Otterbring alexandra Festila Department of Management University of AgderKristiansandNorway Freelancer CopenhagenDenmark

One of the greatest public health crises in recent times,the COVID-19 pandemic,has come with a myriad of challenges in terms of health communication and public cooperation to prevent the spread of the ***-derstanding which are the key determinants that make certain individuals more cooperative is key in effectively tackling pandemics and similar future *** the present study(N=800),we investigated whether gen-der differences in compliance with preventive health behaviors(PHB)at the onset of the COVID-19 pandemic could be established,and,if so,whether the personality traits of agreeableness and conscientiousness could help explain this presumed *** with our theorizing,we found women to score higher than men on agreeableness and conscientiousness,and to be more willing to comply with a set of ***,both per-sonality traits were found to mediate the gender-compliance *** means that women’s greater compliance levels with PHB could,at least in part,be attributed to their higher agreeableness and conscientiousness scores.A greater understanding of the determinants of PHB in terms of gender and associated personality traits may help identify options for developing more effective communication campaigns,both in terms of communication channel selection and message content.

关键词： Covid-19 Pandemics Gender,personality Psychology Agreeableness Conscientiousness Preventive health behaviors

Lineage plasticity-mediated therapy resistance in prostate cancer

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Asian Journal of Andrology 2019年第3期21卷 241-248页

作者： alexandra M Blee Haojie Huang Department of Biochemistry and Molecular Biology Mayo Clinic College of Medicine Rochester MN 55905 USA Biochemistry and Molecular Biology Graduate Program Mayo Clinic Graduate School of Biomedical Sciences Rochester MN 55905 USA Department of Urology Mayo Clinic College of Medicine Rochester MN 55905 USA Mayo Clinic Cancer Center Mayo Clinic College of Medicine Rochester MN 55905 USA

Therapy resistance is a significant challenge for prostate cancer treatment in clinic. Although targeted therapies such as androgen deprivation and androgen receptor (AR) inhibition are effective initially, tumor cells eventually evade these strategies through multiple mechanisms. Lineage reprogramming in response to hormone therapy represents a key mechanism that is increasingly observed. The studies in this area have revealed specific combinations of alterations present in adenocarcinomas that provide cells with the ability to transdifferentiate and perpetuate AR-independent tumor growth after androgen-based therapies. Interestingly, several master regulators have been identified that drive plasticity, some of which also play key roles during development and differentiation of the cell lineages in the normal prostate. Thus, further study of each AR-independent tumor type and understanding underlying mechanisms are warranted to develop combinational therapies that combat lineage plasticity in prostate cancer.

关键词： lineage plasticity neuroendocrine prostate cancer therapy resistance transdifferentiation

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缓解住房抵押贷款市场风险的宏观审慎政策

中国金融 2024年第2期 21-24页

作者：亚历山德拉·瓦拉迪詹姆斯·瓦德尔张林(译) 英格兰银行宏观金融风险局《中国金融》编辑部

英格兰银行金融政策委员会推出两项管控抵押贷款的政策工具,防止放贷机构降低审贷标准以及高负债家庭数量上升所引发的住房市场风险在英国,负责制定住房金融政策工具的宏观审慎监管机构是英格兰银行金融政策委员会(Financial Policy Com... 详细信息

英格兰银行金融政策委员会推出两项管控抵押贷款的政策工具,防止放贷机构降低审贷标准以及高负债家庭数量上升所引发的住房市场风险在英国,负责制定住房金融政策工具的宏观审慎监管机构是英格兰银行金融政策委员会(Financial Policy Committee,FPC)。FPC的主要职责是确保英国金融体系具备抵御各种风险的韧性,其中包括抵御来自英国抵押贷款市场的风险(注:本文的“抵押贷款”均指住房抵押贷款)。英格兰银行应对这些风险的政策工具十分丰富,既有针对购房自住抵押贷款的工具,也有针对购房出租抵押贷款的工具。

关键词：英格兰银行抵押贷款宏观审慎政策放贷机构住房市场高负债宏观审慎监管金融体系

Imposing temporal consistency on deep monocular body shape and pose estimation

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Computational Visual Media 2023年第1期9卷 123-139页

作者： alexandra Zimmer Anna Hilsmann Wieland Morgenstern Peter Eisert Fraunhofer Heinrich-Hertz-Institut 10587 BerlinGermany Technische Universit¨at Berlin 10623 BerlinGermany Humboldt Universit¨at zu Berlin 10117 BerlinGermany

Accurate and temporally consistent modeling of human bodies is essential for a wide range of applications,including character animation,understanding human social behavior,and AR/VR *** human motion accurately from a monocular image sequence remains challenging;modeling quality is strongly influenced by temporal consistency of the captured body *** work presents an elegant solution to integrating temporal constraints during *** increases both temporal consistency and robustness during *** detail,we derive parameters of a sequence of body models,representing shape and motion of a *** optimize these parameters over the complete image sequence,fitting a single consistent body shape while imposing temporal consistency on the body motion,assuming body joint trajectories to be linear over short *** approach enables the derivation of realistic 3D body models from image sequences,including jaw pose,facial expression,and articulated *** experiments show that our approach accurately estimates body shape and motion,even for challenging movements and ***,we apply it to the particular application of sign language analysis,where accurate and temporally consistent motion modelling is essential,and show that the approach is well-suited to this kind of application.

关键词： motion capture surface reconstruction face modeling body model estimation

Laparoscopic ultrasonography as an alternative to intraoperative cholangiography during laparoscopic cholecystectomy

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World Journal of Gastroenterology 2017年第29期23卷 5438-5450页

作者： alexandra Dili Claude Bertrand Unit of Digestive Endocrine and General Surgery Department of Surgery University Hospital - Godinne Université catholique de Louvain

To assess the role of laparoscopic ultrasound (LUS) as a substitute for intraoperative cholangiography (IOC) during cholecystectomy. METHODSWe present a MEDLINE and PubMed literature search, having used the key-words “laparoscopic intraoperative ultrasound” and “laparoscopic cholecystectomy”. All relevant English language publications from 2000 to 2016 were identified, with data extracted for the role of LUS in the anatomical delineation of the biliary tract, detection of common bile duct stones (CBDS), prevention or early detection of biliary duct injury (BDI), and incidental findings during laparoscopic cholecystectomy. Data for the role of LUS vs IOC in complex situations (i.e., inflammatory disease/fibrosis) were specifically analyzed. RESULTSWe report data from eighteen reports, 13 prospective non-randomized trials, 5 retrospective trials, and two meta-analyses assessing diagnostic accuracy, with one analysis also assessing costs, duration of the examination, and anatomical mapping. Overall, LUS was shown to provide highly sensitive mapping of the extra-pancreatic biliary anatomy in 92%-100% of patients, with more difficulty encountered in delineation of the intra-pancreatic segment of the biliary tract (73.8%-98%). Identification of vascular and biliary variations has been documented in two studies. Although inflammatory disease hampered accuracy, LUS was still advantageous vs IOC in patients with obscured anatomy. LUS can be performed before any dissection and repeated at will to guide the surgeon especially when hilar mapping is difficult due to fibrosis and inflammation. In two studies LUS prevented conversion in 91% of patients with difficult scenarios. Considering CBDS detection, LUS sensitivity and specificity were 76%-100% and 96.2%-100%, respectively. LUS allowed the diagnosis/treatment of incidental findings of adjacent organs. No valuable data for BDI prevention or detection could be retrieved, even if no BDI was documented in the reports analyzed. L

关键词： Intraoperative ultrasound Laparoscopic cholecystectomy Bile duct injury Choledocolithiasis Biliary anomalies

Optimisation of zeolite LTA synthesis from alum sludge and the influence of the sludge source

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Journal of Environmental Sciences 2021年第1期33卷 130-142页

作者： alexandra Rozhkovskaya Jay Rajapakse Graeme J.Millar School of Civil and Enuironmental Engineering Science and Engineering FacultyQueensland University oTechnologyBrisbaneQueensland 4000Australia Institute for Future Environments and School of Mechanical Medical and Process EngineeringQueensland Uniuersity of TechnologyBrisbaneQueensland 4000Australia

Generation of alum sludge(AS)at drinking water treatment plants represents an environmental liability and adds to the cost of water ***,this study explored the feasibility of using low and high carbon containing alum sludge from two water treatment plants to synthesize zeolite *** hypothesis was that zeolite LTA synthesis was dependant upon alum sludge source and that a range of strategies may be required to optimize zeolite *** characteristics such as morphology,phase composition,crystallinity,and particle size distribution were recorded."One pot"hydrothermal synthesis of precursor gel with molar composition 4.2 Na2O:Al2O3:1.2 SiO_(2):168 H2O at 80℃ for 3 hr resulted in 25 and 46 wt.%zeolite LTA from high and low carbonaceous sludge,*** to hydrothermal reaction stage it was discovered that ageing of the gel,addition of zeolite LTA seeds,ultrasonic treatment and calcination all promoted zeolite LTA *** of the alum sludge at 700℃ for 2 hr before hydrothermal synthesis resulted in particle size reduction and the highest amount of crystalline zeolite LTA:79 wt.%from low carbon sludge and 65 wt.%from high carbon ***,the zeolite crystallinity reported in this study was the higher than previous studies on this *** outlined approach may allow value adding of alum waste and produce a commodity which could be used locally by the water treatment plant as a water softener.

关键词： Alum sludge Zeolite LTA Ultrasonic Ageing Waste conversion

Layer-like FAU-type zeolites:A comparative view on different preparation routes

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Frontiers of Chemical Science and Engineering 2020年第2期14卷 127-142页

作者： Bastian Reiprich Tobias Weissenberger Wilhelm Schwieger alexandra Inayat Institute of Chemical Reaction Engineering Friedrich-Alexander University Erlangen-NumbergErlangen 91058Germany

The creation of intergrown layer-like zeolite crystals is one route to form hierarchical ***-type(FAU-type)zeolites are among the industrially most important zeolites and the implementation of hierarchical porosity is a promising way to optimise their catalytic and adsorptive *** a short general survey into routes for the preparation of hierarchical pore systems in FAU,we will review the currently existing strategies for the synthesis of FAU with layer-like *** strategies are mainly based on the presence of morphology modifying agents in the synthesis ***,a very recent approach is the synthesis of layer-like FAU-type zeolite crystals assembled in an intergrown manner in the absence of such additives,just by finely adjusting the crystallization *** additive-free preparation route for layer-like FAU,which appears very attractive from an ecological as well as economic point of view,is highlighted in this ***,a comparison,including powder X-ray diffraction,scanning and transmission electron microscopy,nitrogen physisorption and elemental analysis,between conventional FAU and three layer-like FAU obtained by different synthesis routes was carried out to show the structural,morphological and textural differences and similarities of these materials.

关键词： FAU hierarchical zeolite layer-like morphology

Calculating densities and viscosities of natural gas with a high content of C_(2+) to predict two-phase liquid-gas flow pattern

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Petroleum 2023年第4期9卷 579-591页

作者： Yekaterina Moisseyeva alexandra Saitova Sergey Strokin Peter the Great St.Petersburg Polytechnic University Russian Federation

The paper is devoted to the two-phase flow *** gas-condensate mixture flow in a horizontal pipe under high pressure is *** influence of the equation of state(EOS)choice for mixture properties modelling on the flow regime calculation results is studied for gas with high content of methane *** analytical overview of the methods to predict the flow pattern is *** on this analysis,two techniques are *** these techniques,values of density and viscosity for each phase are *** calculation for the gas phase is performed with Van der Waals based *** propriate EOS is selected based on studies of calculation errors for test *** of liquid phase density is done by means of Patela-Teja and Guo-Du equations,two different models are considered for viscosity *** flow patterns of gas-condensate mixture in a range of temperatures and pressures are calculated and verified via probability *** results of study allow to recommend the Brusilovsky EOS for calculation of densities for similar gas mixtures and make more rigorous flow regime *** probability map shows that for the chosen composition and parameters of media the flow pattern is mostly transitional between segregated and annular independent from EOS.

关键词： Two-phase flow Flow pattern Natural gas Wet gas High content of C_(2+) High pressure

Parallel patterns and trends in functional structures in extinct island mammals

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Integrative Zoology 2014年第2期9卷 167-182页

作者： alexandra A.E.VAN DER GEER Naturalis Netherlands Biodiversity Center LeidenNetherlands

Endemic mammalian species on islands are generally known to have followed a different evolutionary pathway than their mainland relatives. General patterns, such as body size trends, have been described regularly. How-ever, most island mammal species are unique and each of them is adapted to a specific local niche as part of an equally specific ecological assemblage. Therefore, comparing island species across taxa, islands and time is in-herently dangerous without understanding the adaptational value of the studied feature in the compared taxa and without taking the ecological setting of the taxa into account. In this contribution, general and recurring patterns are described per taxon. Some features, like body mass change and sturdy limbs, are relatively general, where-as most features, like bone fusions and change of orbital axis, occur only in a very few taxa. Some features are even contradictory, such as brain size and degree of hypsodonty, with each taxon having its own particular de-sign. In conclusion, general patterns are more often than not just trends and need to be applied with caution.

关键词： body proportions fossil record island rule paleo-insular mammals Pleistocene

Post-dispersal seed predation of three grassland species in a plant diversity experiment

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Journal of Plant Ecology 2013年第6期6卷 468-479页

作者： Gesine Pufal alexandra-Maria Klein Institute of Ecology Leuphana UniversityScharnhorststr.121335 LüneburgGermany

Aims Post-dispersal seed predation is an important ecosystem process because it can influence the seed’s fate after the initial dispersal from the mother plant and subsequently transform *** at small scales,post-dispersal seed predation can vary greatly depending on seed identity,granivorous taxa or microhabitat ***,little is known about the role of plant species richness and functional group richness in post-dispersal seed *** overall aim of this study was to test whether increasing plant species richness or plant functional group richness affects the rate and variability of post-dispersal seed *** additionally investigated the influence of vegetation structure and seed species identity on the rate and variability of post-dispersal seed predation and whether the influence of different granivorous taxa changed with increasing plant species *** We conducted seed removal experiments along a long-term experimental plant diversity gradient,comprising plots with monocultures to 60 species mixtures of common grassland species in Jena,Germany,in August *** studied seeds of Onobrychis viciifolia,Pastinaca sativa and Trifolium pratense in exclusion experiments(seed cafeterias),an experimental setup that allowed access either for arthropods or slugs or for all granivorous ***,seeds removed from seed cafeterias were classified as consumed but we used traceable fluorescent-coloured seeds to obtain more accurate predation rates by subtracting recovered seeds from overall removed *** effect of multiple vegetation variables on mean and variability of seed predation rates was analysed using generalized mixed-effect models and linear regressions,*** Findings Rates of recovered seeds were low but contributed to significant differences between seed predation rates and removal rates of seeds in some *** predation rates were not directly correlated with increasing plant spe

关键词： arthropods cafeteria-style experiments ecosystem functions granivorous taxa slugs