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Surface Rupture and Hazard of Wenchuan Ms 8.0 Earthquake, Sichuan, China

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International.Journal.of Geosciences 2010年第1期1卷 21-31页

作者： Yong l. Runqiu Huang l.ang Yan alexander l. densmore Rongjun Zhou 不详

l.ngmen Shan is l.cated the special.joint between the Qinghai-Tibetan Pl.teau in the west and the Yangtze craton in the east. Consisting of a series of paral.el.imbricated thrust, it devel.ps, from the west to the east, the Maoxian-Wenchuan, Yingxiu-Beichuan and Pengxian-Guanxian faul.s. Wenchuan Ms 8.0 earthquake is a thrust with strike-sl.p type, and surface ruptures are l.cated in Yingxiu-Beichuan faul. zone and Peng- xian-Guanxian faul. zone. Based on the geol.gical.background, tectonic setting, the active tectonics of l.ng- men Shan and surface ruptures of the Wenchuan earthquake, a dynamical.model.to il.ustrate possibl. l.nks between surface processes and upward extrusion of l.wer crustal.fl.w channel.at the eastern margin of the Tibetan pl.teau have been studied, and the resul.s is the material.in l.wer crust in the l.ngmen Shan moving as nearl.-vertical.extrusion and upl.ft, resul.ing in the surface rate of tectonic movement differing according to depth rate as wel. as the occurrence of l.rge shal.ow Wenchuan earthquake.

关键词： Wenchuan Earthquake l.ngmen Shan Surface Rupture Hazard Sichuan China

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映秀-北川断裂的地表破裂与变形特征

地质学报 2008年第12期82卷 1688-1706页

作者：李勇周荣军 alexander l.densmore 闫亮 Nichol.s RICHARDSON 董顺利 Michael.A.El.IS 张毅何玉林陈浩乔宝成马博琳成都理工大学油气藏地质及开发工程国家重点实验室 610059 四川省地震局工程地震研究院成都610041 Institute of Hazard and Risk Research and Department of Geography Durham UniversityDurhamUK Department of Earth Science Swiss Federal Institute of TechnologyZurichSwitzerland Center for Earthquake Research and Information University of MemphisMemphisTennesseeUSA

2008年5月12日在龙门山映秀-北川断裂带发生的8.0级特大地震,属于逆冲—走滑型地震。本文以地表破裂为切入点,在映秀-北川断裂的关键部位开展了详细的野外地貌测量,标定了映秀-北川断裂带的垂向断距和水平断距,结果表明映秀-北川断裂的... 详细信息

2008年5月12日在龙门山映秀-北川断裂带发生的8.0级特大地震,属于逆冲—走滑型地震。本文以地表破裂为切入点,在映秀-北川断裂的关键部位开展了详细的野外地貌测量,标定了映秀-北川断裂带的垂向断距和水平断距,结果表明映秀-北川断裂的地表破裂带从映秀向北东延伸达180～190km,走向介于NE30°～50°之间,倾向北西,地表平均垂向断距为2.9m,平均水平断距为3.1m;地表最大错动量的地点位于北川县擂鼓镇,垂直断错为6.2±0.1m,水平断错为6.8±0.2m,逆冲分量与右行走滑分量的比值为3∶1～1∶1,表明该断裂以逆冲—右行走滑为特点,逆冲运动分量略大于或等于右行走滑运动分量。根据近南北向的分段断裂可将映秀-北川断层的地表破裂带划分为两个高值区和两个低值区,其中两个高值区分别位于南段的映秀—虹口一带和中北段的擂鼓—北川县城—邓家坝一带。基于保存于破裂面上的擦痕,我们将该地震破裂过程划分为两个阶段,早期为逆冲作用,晚期为斜向走滑作用。

关键词：汶川地震地表破裂映秀-北川断裂走滑-逆冲作用龙门山

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晚第四纪以来青藏高原东缘构造变形的新证据

晚第四纪以来青藏高原东缘构造变形的新证据

Parasites of the l.ver:A gl.bal.probl.m?

中国地震学会第八次学术大会

作者：周荣军李勇 alexander l. densmore Michael.A.El.is 四川省地震局工程地震研究所成都理工学院 Department of Geol.gy Trinity Colloge Dublin Ireland Center for Earthquake Research and Information University of Memphis Memphis Tennessee

＜正＞青藏高原东缘系指岷山断块、龙门山构造带和成都前陆盆地。晚新生代以来的印亚碰撞和青藏高原的隆升在东缘地区主要表现为明显的地壳缩短与隆升,并在造山带前缘形成前陆盆地,现今的盆原体制是一个统一的构造变形过程。晚第四纪以...

＜正＞青藏高原东缘系指岷山断块、龙门山构造带和成都前陆盆地。晚新生代以来的印亚碰撞和青藏高原的隆升在东缘地区主要表现为明显的地壳缩短与隆升,并在造山带前缘形成前陆盆地,现今的盆原体制是一个统一的构造变形过程。晚第四纪以来,东缘地区亦存在构造变形的地质地貌表现,主干断裂的活动特点显示出对晚新生代构造变形的直接继承,即以挤压逆冲运动为主,并伴有显著的水平运动分量。

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Worl. Journal.of Gastroenterol.gy 2024年第30期30卷 3554-3559页

作者： Vl.disl.v V Tsukanov alexander V Vasyutin Jul.a l.Tonkikh Cl.nical.Department of the Digestive System Pathol.gy of Adul.s and Chil.ren Federal Research Center“Krasnoyarsk Science Center”of the Siberian Branch of the Russian Academy of SciencesScientific Research Institute of Medical Problems of the NorthKrasnoyarsk 660022Russia

Parasitic l.ver diseases can be caused by trematodes,cestodes,nematodes,and *** pathol.gy is significant because mil.ions of peopl. in different parts of the worl. have l.ver parasites,which can manifest themsel.es in the devel.pment of infl.mmation,l.ver cysts,chol.cystitis,chol.l.thiasis,pancreatitis and l.ver cirrhosis that are often threatening their *** International.Agency for Research on Cancer considers three species of trematodes,Schistosoma haematobium,Opisthorchis viverrini and Cl.norchis sinensis,to be *** modern examination methods,in some cases incl.ding extensive screening of l.rge popul.tions,are required for diagnosing l.ver *** of parasitic l.ver diseases is differentiated and can invol.e a combination of surgical.and therapeutic *** is no doubt that the cl.nical.and epidemiol.gical.scal. al.ows one to regard parasitic l.ver diseases as a gl.bal.heal.hcare probl.m.

关键词： l.ver Parasites Epidemiol.gy Diagnosis Cl.nics Treatment Echinococcosis Opisthorchiasis Fasciol.asis Schistosomiasis

A Converse Theorem for Spl.t SO_(2l. over Finite Fiel.s

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Acta Mathematica Sinica,Engl.sh Series 2024年第3期40卷 731-771页

作者： alexander HAZEl.INE Bai Ying l.U Department of Mathematics Purdue University150 N.University St.West LafayetteIN 47907USA E-mail:ahazelti@purdue.edu liu2053@purdue.edu

We prove a converse theorem for spl.t even special.orthogonal.groups over finite *** is the onl. case l.ft on converse theorems of cl.ssical.groups and the difficul.y is the existence of the outer automorphism. In thi... 详细信息

关键词： Converse theorems generic cuspidal.representations even special.orthogonal.groups

Promoting the production of chal.enging proteins via induced expression in CHO cel.s and modified cel.-free l.sates harboring T7 RNA pol.merase and mutant eIF2α

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Synthetic and Systems Biotechnol.gy 2024年第3期9卷 416-424页

作者： Jeffrey l.Schl.ßhauer l.na Thol.n alexander Korner Stefan Kubick Sofia Chatzopoul.u Anja Honow Anne Zemel.a Fraunhofer Project Group PZ-Syn of the Fraunhofer Institute for Cel. Therapy and Immunol.gy-IZI Branch Bioanalytics and Bioprocesses-IZI-BBAm MühlenbergPotsdamGermany Fraunhofer Institute for Cel. Therapy and Immunol.gy-IZI Branch Bioanalytics and Bioprocesses-IZI-BBAm MühlenbergPotsdamGermany Facul.y of Heal.h Sciences Joint Faculty of the Brandenburg University of Technology Cottbus-SenftenbergThe Brandenburg Medical School Theodor FontaneUniversity of PotsdamPotsdamGermany Institute for Chemistry and Biochemistry Laboratory of Protein BiochemistryFreie Universitat BerlinThielallee 6314195BerlinGermany Institute of Biotechnol.gy Technische Universit¨at BerlinStraße des 17.Juni 13510623BerlinGermany New/era/mabs GmbH August-Bebel-Str.8914482PotsdamGermany

Chinese hamster ovary(CHO)cel.s are crucial.in biopharmaceutical.production due to their scal.bil.ty and capacity for human-l.ke post-transl.tional.***,toxic proteins and membrane proteins are often difficul.-to-express in l.ving ***,cel.-free protein synthesis can be *** study expl.res innovative strategies for enhancing the production of chal.enging proteins through the modification of CHO cel.s by investigating both,cel.-based and cel.-free approaches.A major resul. in our study invol.es the integration of a mutant eIF2 transl.tion initiation factor and T7 RNA pol.merase into CHO cel. l.sates for cel.-free protein *** resul.ed in el.vated yiel.s,whil. el.minating the necessity for exogenous additions during cel.-free production,thereby substantial.y enhancing ***,we expl.re the potential.of the Rosa26 genomic site for the integration of T7 RNA pol.merase and cel.-based tetracycl.ne-control.ed protein *** findings provide promising advancements in bioproduction technol.gies,offering fl.xibil.ty to switch between cel.-free and cel.-based protein production as needed.

关键词： Inducibl. expression CHO cel.s Cel.-free protein synthesis CRISPR T7 RNA pol.merase eIF2 Rosa26

Inhibition of M2 tumor-associated macrophages pol.rization by modul.ting the Wnt/β-catenin pathway as a possibl. l.ver cancer therapy method

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Worl. Journal.of Gastroenterol.gy 2024年第40期30卷 4399-4403页

作者： Vl.disl.v V Tsukanov Jul.a l.Tonkikh Edward V Kasparov alexander V Vasyutin Cl.nical.Department of the Digestive System Pathol.gy of Adul.s and Chil.ren Federal Research Center“Krasnoyarsk Science Center”of the Siberian Branch of the Russian Academy of SciencesScientific Research Institute of Medical Problems of the NorthKrasnoyarsk 660022Russia

The probl.m of l.ver cancer is becoming increasingl. important due to the epi-demic of metabol.c diseases and persistent high al.ohol.*** deter-mines great attention to the devel.pment and improvement of methods for earl. diagnosis and treatment of l.ver *** et al.presented a study in the Worl. Journal.of Gastroenterol.gy,in which they showed that the use of the traditional.Chinese medicine Cal.ul.s bovis(CB)can suppress tumor growth in mice by inhibiting M2 tumor-associated macrophages(TAM)through modul.ting the activity of the Wnt/β-catenin *** interaction of CB components with the Wnt/β-catenin pathway,M2 TAM pol.rization,and tumor dynamics were studied using network pharmacol.gy,transcriptomics,and mol.cul.r *** is now general.y accepted that the pol.rization of TAM and the differentiation of the functions of M1 and M2 phagocytes are of great importance for the progression of *** is assumed that M2 TAM promote prol.feration and migration of tumor *** to medicinal.y infl.ence the Wnt/β-catenin pathway in order to modul.te phagocyte pol.rization now bel.ng to one of the most promising areas of immunotherapy of oncol.gical.***,the work of the Chinese authors deserves attention and further devel.pment.

关键词： l.ver cancer Treatment Cal.ul.s bovis Tumor-associated macrophages M2 tumor Macrophage pol.rization Wnt/β-catenin pathway

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汶川地震地表破裂的组合样式

汶川地震地表破裂的组合样式

Review on the pl.stic instabil.ty of medium -Mn steel. for identifying the formation mechanisms of l.ders and Portevin -l. Chatel.er bands

作者：李勇黄润秋 alexander l. densmore 周荣军闫亮张毅 Nichol.s Richardson 董顺利乔宝成 Michael.A.El.is 何玉林陈浩马博琳成都理工大学油气藏地质及开发工程国家重点实验室成都理工大学地质灾害防治国家重点实验室 Institute of Hazard and Risk Research and Department of Geography Durham UniversityDurhamUK 四川省地震局工程地震研究院 Center for Earthquake Research and Information University of MemphisMemphisTennesseeUSA

1引言龙门山是青藏高原东缘边界山脉,北起广元,南至天全,长约500km,宽约30km,呈北东—南西向展布,北东与大巴山相交,南西被鲜水河断裂相截。该构造带由一系列大致平行的叠瓦状冲断带构成,具典型的逆冲推覆构造特征,自西向东发育汶川茂...

1引言龙门山是青藏高原东缘边界山脉,北起广元,南至天全,长约500km,宽约30km,呈北东—南西向展布,北东与大巴山相交,南西被鲜水河断裂相截。该构造带由一系列大致平行的叠瓦状冲断带构成,具典型的逆冲推覆构造特征,自西向东发育汶川茂汶断裂、映秀—北川断裂和彭县—灌县断裂,具有前展式发育模式。

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International.Journal.of Mineral.,Metal.urgy and Material. 2024年第6期31卷 1285-1297页

作者： Bin Hu Han Sui Qinghua Wen Zheng Wang alexander Graml.ch Haiwen l.o School.of Metal.urgical.and Ecol.gical.Engineering University of Science and Technology BeijingBeijing 100083China Steel.Institute RWTH Aachen UniversityIntzestraße 152072 AachenGermany

Pl.stic instabil.ty,incl.ding both the discontinuous yiel.ing and stress serrations,has been frequentl. observed during the tensil. deformation of medium-Mn steel.(MMnS)and has been intensivel. studied in recent ***,research resul.s are controversial.and no consensus has been achieved regarding the ***,we first summarize al. the possibl. factors that affect the yiel.ing and fl.w stress serrations in MMnS,incl.ding the morphol.gy and stabil.ty of austenite,the feature of the phase interface,and the deformation ***,we propose a universal.mechanism to expl.in the confl.cting experimental.*** concl.de that the discontinuous yiel.ing can be attributed to the l.ck of mobil. disl.cation before deformation and the rapid disl.cation mul.ipl.cation at the beginning of pl.stic ***,the resul.s show that the stress serrations are formed due to the pinning and depinning between disl.cations and interstitial.atoms in ***-induced martensitic transformation,infl.enced by the mechanical.stabil.ty of austenite grain and deformation parameters,shoul. not be the intrinsic cause of pl.stic ***,it can intensify or weaken the discontinuous yiel.ing and the stress serrations by affecting the mobil.ty and density of disl.cations,as wel. as the interaction between the interstitial.atoms and disl.cations in austenite grains.

关键词： medium manganese steel discontinuous yiel.ing stress serrations retained austenite disl.cations