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Diffusion weighted magnetic resonance imaging of liver: Principles, clinical applications and recent updates

World Journal of Hepatology 2017年第26期9卷 1081-1091页

作者： Anuradha Shenoy-Bhangle Vinit Baliyan Hamed Kordbacheh alexander r guimaraes Avinash Kambadakone Beth Israel Deaconess Medical Center Harvard Medical School Abdominal Imaging and Interventional Radiology Massachusetts General Hospital Oregon Health and Science University

Diffusion-weighted imaging(DWI), a functional imaging technique exploiting the Brownian motion of water molecules, is increasingly shown to have value in various oncological and non-oncological applications. Factors such as the ease of acquisition and ability to obtain functional information in the absence of intravenous contrast, especially in patients with abnormal renal function, have contributed to the growing interest in exploring clinical applications of DWI. In the liver, DWI demonstrates a gamut of clinical applications ranging from detecting focal liver lesions to monitoring response in patients undergoing serial follow-up after loco-regional and systemic therapies. DWI is also being applied in the evaluation of diffuse liver diseases such as non-alcoholic fatty liver disease, hepatic fibrosis and cirrhosis. In this review, we intend to review the basic principles, technique, current clinical applications and future trends of DW-MrI in the liver.

关键词： Liver imaging Diffusion weighted imaging Magnetic resonance imaging Focal liver lesion Diffuse liver disease response assessment

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Simultaneous whole body ^(18)F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging for evaluation of pediatric cancer: Preliminary experience and comparison with ^(18)F-fluorodeoxyglucose positron emission tomography computed tomogra

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World Journal of radiology 2016年第3期8卷 322-330页

作者： Brian S Pugmire alexander r guimaraes ruth Lim Alison M Friedmann Mary Huang David Ebb Howard Weinstein Onofrio A Catalano Umar Mahmood Ciprian Catana Michael S Gee Department of radiology Cincinnati Children’s Hospital Medical Center Division of Body Imaging Oregon Health Sciences University Division of Abdominal Imaging Massachusetts General Hospital Martinos Center for Biomedical Imaging Division of Nuclear Medicine and Molecular Imaging Massachusetts General Hospital Division of Pediatric Imaging Mass General Hospital for Children Division of Pediatric Hematology-Oncology Mass General Hospital for Children

AIM: To describe our preliminary experience with simultaneous whole body ^(18)F-fluorodeoxyglucose(^(18)F-FDG)positron emission tomography and magnetic resonance imaging(PET-MrI) in the evaluation of pediatric oncology ***: This prospective, observational, singlecenter study was Health Insurance Portability and Accountability Act-compliant, and institutional review board approved. To be eligible, a patient was required to:(1) have a known or suspected cancer diagnosis;(2) be under the care of a pediatric hematologist/oncologist; and(3) be scheduled for clinically indicated ^(18)F-FDG PETCT examination at our institution. Patients underwent PET-CT followed by PET-MrI on the same day. PET-CT examinations were performed using standard department protocols. PET-MrI studies were acquired with an integrated 3 Tesla PET-MrI scanner using whole body T1 Dixon, T2 HASTE, EPI diffusion-weighted imaging(DWI) and STIr sequences. No additional radiotracer was given for the PET-MrI examination. Both PET-CT and PETMrI examinations were reviewed by consensus by two study personnel. Test performance characteristics of PETMrI, for the detection of malignant lesions, including FDG maximum standardized uptake value(SUVmax) and minimum apparent diffusion coefficient(ADCmin), were calculated on a per lesion basis using PET-CT as a reference ***: A total of 10 whole body PET-MrI exams were performed in 7 pediatric oncology patients. The mean patient age was 16.1 years(range 12-19 years) including 6 males and 1 female. A total of 20 malignant and 21 benign lesions were identified on PET-CT. PET-MrI SUVmax had excellent correlation with PET-CT SUVmax for both benign and malignant lesions(r = 0.93). PETMrI SUVmax > 2.5 had 100% accuracy for discriminating benign from malignant lesions using PET-computed tomography(CT) reference. Whole body DWI was also evaluated: the mean ADCmin of malignant lesions(780.2 + 326.6) was significantly lower than that of benign lesions(1

关键词： Positron emission tomography radiology Pediatric imaging Oncology Cancer Magnetic resonance imaging

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前瞻性盲法比较无线胶囊内镜与多期CT小肠成像对不明原因胃肠道出血的价值

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国际医学放射学杂志 2011年第6期 579-580页

作者： J.E.Huprich J.G.Fletcher J.L.Fidler J.A.alexander L.S.guimaraes H.A.Siddiki 赵晓娟 Department of radiology Mayo Clinic200 First St SWRochesterMN 55905

目的比较多期CT小肠成像与胶囊内镜在一组不明原因胃肠道出血(obscure gastrointestinal bleeding,OGIB)病人中的作用。材料与方法本前瞻性研究符合HIPAA要求,并获得机构审查委员会及利益冲突委员会批准。

关键词：小肠出血胃肠道出血不明原因胶囊内镜多期 CT

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