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The differential benefit of laparoscopic over open minor liver resection for lesions situated in the anterolateral or posterosuperior segments

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Hepatobiliary Surgery and Nutrition 2024年第4期13卷 604-615,I0015-I0021页

作者： Jasper P.Sijberden Guido Fiorentini Jacopo Lanari Davit Aghayan Daniel Osei-Bordom Nadia Russolillo Arjun Takhar Andrea Benedetti Cacciaguerra Santi Lopez-Ben Mathieu D’Hondt Felice Giuliante David Fuks Fernando Rotellar Andrea Ruzzenente Adnan Alseidi Mikhail Efanov Burak Görgec Giuseppe Zimmitti Enrico Gringeri Federica Cipriani Åsmund Avdem Fretland Ravi Marudanayagam Marco Vivarelli John N.Primrose alessandro ferrero Robert P.Sutcliffe Bjørn Edwin Umberto Cillo Marc G.Besselink Mohammad Abu Hilal Luca A.Aldrighetti Department of Surgery Fondazione Poliambulanza Istituto OspedalieroBresciaItaly Amsterdam UMC location University of Amsterdam Department of SurgeryAmsterdamthe Netherlands Cancer Center Amsterdam Amsterdamthe Netherlands Hepatobiliary Surgery Division IRCCS San Raffaele HospitalMilanItaly Department of Surgical Oncological and Gastroenterological SciencesGeneral Surgery 2Hepatobiliary Surgery and Liver TransplantationPadua University HospitalPaduaItaly The Intervention Centre and Department of HPB Surgery Oslo University Hospital and Institute of Clinical MedicineUniversity of OsloOsloNorway Department of Surgery Ringerike HospitalVestre Viken Hospital TrustDrammenNorway Liver Unit Queen Elizabeth HospitalBirminghamUK Department of General and Oncological Surgery Umberto I Mauriziano HospitalLargo TuratiTurinItaly Department of Surgery University Hospital Southampton NHS Foundation TrustSouthamptonUK Hepatobiliary and Abdominal Transplantation Surgery Department of Experimental and Clinical MedicineRiuniti HospitalPolytechnic University of MarcheAnconaItaly Servei de Cirurgia General i Digestiva Hospital Doctor Josep Trueta de GironaGironaCataloniaSpain Department of Digestive and Hepatobiliary/Pancreatic Surgery Groeninge HospitalKortrijkBelgium Chirurgia Epatobiliare UniversitàCattolica del Sacro Cuore-IRCCSRomeItaly Department of Digestive Oncologic and Metabolic SurgeryInstitut Mutualiste MontsourisUniversitéParis DescartesParisFrance HPB and Liver Transplantation Unit Department of SurgeryUniversity ClinicUniversidad de NavarraNavarraSpain Institute of Health Research of Navarra(IdisNA) PamplonaSpain Department of Surgery University of VeronaVeronaItaly Department of Surgery Virginia Mason Medical CenterSeattleWAUSA Department of Surgery University of California San FranciscoSan FranciscoCAUSA Department of Hepato-Pancreato-Biliary Surgery Moscow Clinical Research CentreMoscowRussia

Background:It is well known that laparoscopic liver surgery can offer advantages over open liver surgery in selected ***,what type of procedures can benefit most from a laparoscopic approach has been investigated poorly thus *** aim of this study is thus to define the extent of advantages of laparoscopic over open liver surgery for lesions in the anterolateral(AL)and posterosuperior(PS)***:In this international multicentre retrospective cohort study,laparoscopic and open minor liver resections for lesions in the AL and PS segments were compared after propensity score *** differential benefit of laparoscopy over open liver surgery,calculated using bootstrap sampling,was compared between AL and PS resections and expressed as a Delta of the ***:After matching,3,040 AL and 2,336 PS resections were compared,encompassing open and laparoscopic procedures in a 1:1 *** and PS laparoscopic liver resections were more advantageous in comparison to open in terms of blood loss,transfusion rate,complications,and length of ***,AL resections benefitted more from laparoscopy than PS in terms of overall and severe complications(D-difference were 4.8%,P=0.046 and 3%,P=0.046)and blood loss(D-difference was 195 mL,P<0.001).Similar results were observed in the subset for high-volume centres,while in recent years no significant differences were found in the differential benefit between AL and PS ***:The advantage of laparoscopic over open liver surgery is greater in the AL segments than in the PS segments.

关键词： Liver neoplasms hepatectomy laparoscopic liver resection open liver resection

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随机模糊变量表示测量及测量不确定度

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仪器仪表学报 2016年第5期37卷 1065-1078页

作者：蒋薇张玘 alessandro ferrero Marco Prioli Simona Salicone 国防科技大学机电工程与自动化学院长沙410073 米兰理工大学电子信息与生物工程系米兰20133

《测量不确定度表示指南》(GUM)这个技术规范已被广泛认可,且其测量值关联一个不确定度值的建议也被广泛采纳。然而,这个规范遵循一种固有的概率方法,其应用并不总是可行的,且因为一些技术和经济原因,在可行的情况下,其应用也并不是简... 详细信息

《测量不确定度表示指南》(GUM)这个技术规范已被广泛认可,且其测量值关联一个不确定度值的建议也被广泛采纳。然而,这个规范遵循一种固有的概率方法,其应用并不总是可行的,且因为一些技术和经济原因,在可行的情况下,其应用也并不是简单直接的。总结了一种更一般化的不确定度评定和表示的随机模糊变量RFVs方法,系统评述了其关键技术与难点,通过实例表明,RFVs方法在非线性测量函数中传递不确定度具有简单高效的特点,最后对该领域的研究扩展提出了两点建议,给出了使用RFVs扩展贝叶斯定理的初步探讨结果。RFVs方法基于数学可能性理论,从GUM及其基本概念和定义出发对GUM方法进行了扩展,具有明显的优势,该方法的广泛应用也证明了其远大的发展前景。

关键词：测量不确定度随机模糊变量 GUM 可能性理论

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A Possibilistic Approach for Uncertainty Representation and Propagation in Similarity-Based Prognostic Health Management Solutions

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Open Journal of Statistics 2020年第6期10卷 1020-1038页

作者： Loredana Cristaldi alessandro ferrero Simona Salicone Giacomo Leone Dipartimento di Elettronica Informazione e Bioingegneria (DEIB) Politecnico di Milano Milano Italy Sorint.Tek Grassobbio Italy

In this paper, a data-driven prognostic model capable to deal with different sources of uncertainty is proposed. The main novelty factor is the application of a mathematical framework, namely a Random Fuzzy Variable (RFV) approach, for the representation and propagation of the different uncertainty sources affecting Prognostic Health Management (PHM) applications: measurement, future and model uncertainty. In this way, it is possible to deal not only with measurement noise and model parameters uncertainty due to the stochastic nature of the degradation process, but also with systematic effects, such as systematic errors in the measurement process, incomplete knowledge of the degradation process, subjective belief about model parameters. Furthermore, the low analytical complexity of the employed prognostic model allows to easily propagate the measurement and parameters uncertainty into the RUL forecast, with no need of extensive Monte Carlo loops, so that low requirements in terms of computation power are needed. The model has been applied to two real application cases, showing high accuracy output, resulting in a potentially effective tool for predictive maintenance in different industrial sectors.

关键词： Data-Driven Epistemic Uncertainty Measurement Uncertainty Future Uncertainty Prognostics and Health Management Random Fuzzy Variable Remaining Useful Life Similarity

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Robotic versus laparoscopic liver resection for huge (≥10 cm) liver tumors: an international multicenter propensity-score matched cohort study of 799 cases

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Hepatobiliary Surgery and Nutrition 2023年第2期12卷 205-215,I0005页

作者： Tan-To Cheung Rong Liu Federica Cipriani Xiaoying Wang Mikhail Efanov David Fuks Gi-Hong Choi Nicholas L.Syn Charing C.N.Chong Fabrizio Di Benedetto Ricardo Robles-Campos Vincenzo Mazzaferro Fernando Rotellar Santiago Lopez-Ben James O.Park Alejandro Mejia Iswanto Sucandy Adrian K.H.Chiow Marco V.Marino Mikel Gastaca Jae Hoon Lee TPeter Kingham Mathieu D’Hondt Sung Hoon Choi Robert P.Sutcliffe Ho-Seong Han Chung-Ngai Tang Johann Pratschke Roberto I.Troisi Go Wakabayashi Daniel Cherqui Felice Giuliante Davit L.Aghayan Bjorn Edwin Olivier Scatton Atsushi Sugioka Tran Cong Duy Long Constantino Fondevila Mohammad Abu Hilal Andrea Ruzzenente alessandro ferrero Paulo Herman Kuo-Hsin Chen Luca Aldrighetti Brian K.P.Goh International robotic and laparoscopic liver resection study group investigators Department of Surgery Queen Mary HospitalThe University of Hong KongHong Kong SARChina Faculty of Hepatopancreatobiliary Surgery The First Medical Center of Chinese People’s Liberation Army(PLA)General HospitalBeijingChina Hepatobiliary Surgery Division IRCCS San Raffaele HospitalMilanItaly Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghaiChina Department of Hepato-Pancreato-Biliary Surgery Moscow Clinical Scientific CenterMoscowRussia Department of Digestive Oncologic and Metabolic SurgeryInstitute Mutualiste MontsourisUniversite Paris DescartesParisFrance Division of Hepatopancreatobiliary Surgery Department of SurgerySeverance HospitalYonsei University College of MedicineSeoulKorea Department of Hepatopancreatobiliary and Transplant Surgery Singapore General Hospital and Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryPrince of Wales HospitalThe Chinese University of Hong KongHong Kong SARChina HPB Surgery and Liver Transplant Unit University of Modena and Reggio EmiliaModenaItaly Department of General Visceral and Transplantation SurgeryClinic and University Hospital Virgen de la ArrixacaIMIB-ARRIXACAMurciaSpain HPB Surgery Hepatology and Liver TransplantationFondazione IRCCS Istituto Nazionale Tumori di MilanoMilanItaly HPB and Liver Transplant Unit Department of General SurgeryClinica Universidad de NavarraUniversidad de NavarraPamplonaSpain Institute of Health Research of Navarra(IdisNA) PamplonaSpain Hepatobiliary and Pancreatic Surgery Unit Department of SurgeryDr.Josep Trueta HospitalIdIBGiGironaSpain Hepatobiliary Surgical Oncology Department of SurgeryUniversity of Washington Medical CenterSeattleWAUSA The Liver Institute Methodist Dallas Medical CenterDallasTXUSA AdventHealth Tampa Digestive Health InstituteTampaFLUSA Hepatopancreatobiliary Unit Department of SurgeryChangi General

Background:The use of laparoscopic(LLR)and robotic liver resections(RLR)has been safely performed in many institutions for liver tumours.A large scale international multicenter study would provide stronger evidence and insight into application of these techniques for huge liver tumours≥10 ***:This was a retrospective review of 971 patients who underwent LLR and RLR for huge(≥10 cm)tumors at 42 international centers between ***:One hundred RLR and 699 LLR which met study criteria were *** comparison between the 2 approaches for patients with huge tumors were performed using 1:3 propensity-score matching(PSM)(73 vs.219).Before PSM,LLR was associated with significantly increased frequency of previous abdominal surgery,malignant pathology,liver cirrhosis and increased median *** PSM,RLR and LLR was associated with no significant difference in key perioperative outcomes including media operation time(242 vs.290 min,P=0.286),transfusion rate rate(19.2%vs.16.9%,P=0.652),median blood loss(200 vs.300 mL,P=0.694),open conversion rate(8.2%vs.11.0%,P=0.519),morbidity(28.8%vs.21.9%,P=0.221),major morbidity(4.1%vs.9.6%,P=0.152),mortality and postoperative length of stay(6 vs.6 days,P=0.435).Conclusions:RLR and LLR can be performed safely for selected patients with huge liver tumours with excellent *** was no significant difference in perioperative outcomes after RLR or LLR.

关键词： Laparoscopic liver resection(LLR) robotic liver resection(RLR) hepatocellular carcinoma colorectal liver metastases huge

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Bicruciate-retaining total knee arthroplasty: What’s new?

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World Journal of Orthopedics 2021年第10期12卷 732-742页

作者： Luigi Sabatini Luca Barberis Daniele Camazzola Michele Centola Marcello Capella alessandro Bistolfi Marco Schiraldi alessandro Massè Orthopaedics and Traumatology Department Presidio CTOTorino 10126Italy Orthopaedics and Traumatology Department CTO HospitalTorino 10126Italy Orthopedics and Traumaology Department Michele e Pietro Ferrero HospitalVerduno 12060Italy

Primary total knee arthroplasty(TKA)is a widespread procedure to address end stage osteoarthritis with good results,clinical outcomes,and long-term *** it is frequently performed in elderly,an increased demand in young and active people is expected in the next ***,a considerable dissatisfaction rate has been reported by highly demanding patients due to the intrinsic limitations provided by the ***-retaining(BCR)TKA was developed to mimic knee biomechanics,through anterior cruciate ligament ***-generation BCR TKA has not gained popularity due to its being a challenging technique and having poor survival *** to implant design improvement and surgeon-friendly instrumentation,secondgeneration BCR TKA has seen renewed *** review will focus on surgical indications,kinematical basis,clinical results and latest developments of secondgeneration BCR TKA.

关键词： Total knee arthroplasty Anterior cruciate ligament Bicruciate retaining Knee kinematics Second generation design Knee osteoarthritis treatment

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