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Septic arthritis of the hand:Current issues of etiology,pathogenesis,diagnosis,treatment

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World Journal of Orthopedics 2022年第7期13卷 622-630页

作者： Konstantin V Lipatov Arthur Asatryan George Melkonyan aleksandr D Kazantcev Ekaterina I Solov'eva Urii E Cherkasov Department of General Surgery Institute of Clinical Medicine named after N.V.SklifosovskySechenov First Moscow State Medical University(Sechenov University)Moscow 119021Russia Wound and Wound Infection Surgery State Budgetary Institution“City Clinical Hospital named after S.S.Yudin of Moscow Healthcare Department”Moscow 115446Russia Department of General Surgery Physician of The Hospital for War Veterans No 3Moscow 129336Russia Department of General Surgery I.M.Sechenov First Moscow State Medical UniversityMoscow 119048Russia

Septic arthritis of the hand is a serious disease that often results in dysfunction of the joint or even the need to perform amputation of the *** rank second in the frequency of occurrence after lesions of the knee *** points concerning the etiology,the timing of the development of cartilage destruction and the development of osteomyelitis,approaches to surgical treatment,the duration of antibiotic therapy,and the start of rehabilitation measures remain the subject of numerous *** on a search in the PubMed,Web of Science and Google Scholar databases down to 1990-2021,publications on septic arthritis of the hand were found and *** following inclusion criteria were used in our review:(1) Septic arthritis of the hand;(2) Published in a peer review journal;(3) Written in English;and(4) Full text version *** were excluded if they met any of the following criteria:(1) Letters;(2) Articles published in abstract form only;and(3) Cadaveric *** arthritis of the hand was characterized by the most frequent damage to the joints of the index and middle fingers(> 50% of cases).Up to 90% of cases,the infection enters the joint as a result of penetrating trauma,animal bites,*** aureus became the most frequently isolated microorganism(30%-55%),and its polyantibiotic-resistant form Methicillin-resistant Staphylococcus aureus was found,according to various sources,from 0% to 73% among all isolated Staphylococcus *** arthritis,Pasteurella multocida(6%-11%) is often isolated as a result of animal *** cartilage destruction in the experiment developed within 24-48 h after *** clinical studies,the development of osteomyelitis was noted when treatment was delayed by more than 10 d.X-ray data during the first two weeks were *** of surgical treatment of septic *** and surgical treatment,and with the development of osteomyelitis,the implementation of arthro

关键词： Septic arthritis Hand Staphylococcus aureus Metacarpophalangeal joint Interphalangeal joint Rehabilitation

Pancreas-preserving duodenal resections vs pancreatoduodenectomy for groove pancreatitis. Should we revisit treatment algorithm for groove pancreatitis?

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World Journal of Gastrointestinal Surgery 2021年第1期13卷 30-49页

作者： Vyacheslav Egorov Roman Petrov aleksandr Schegolev Elena Dubova Andrey Vankovich Eugeny Kondratyev Andrey Dobriakov Dmitry Kalinin natalia Schvetz Elena Poputchikova Department of Surgical Oncology Ilyinskaya HospitalMoscow 143421Russia V.I.Kulakov Research Center for Obstetrics Ministry Hlth Russian FederatVI Kulakov Res Ctr Obstet Gynecol&PerinatolMoscow 119526Russia Department of Pathology Buranazian Federal Medical and Biological Center of the Federal Medical and Biological Agency of Russian FederationMoscow 143421Russia Department of HPB Surgery Moscow Clinical Research CenterMoscow 111123Russia Department of Radiology Vishnevsky Institute of SurgeryIlyinskaya HospitalMoscow 143421Russia Department of Pathology Bakhrushin Brothers Moscow City HospitalMoscow 107076Russia Department of Pathology Vishnevsky Institute of SurgeryIlyinskaya HospitalMoscow 117997Russia

BACKGROUnD The management of cystic dystrophy of the duodenal wall(CDDW),or groove pancreatitis(GP),remains *** pancreatoduodenectomy(PD)is considered the most suitable operation for CDDW,pancreas-preserving duodenal resection(PPDR)has also been suggested as an alternative for the pure form of GP(isolated CDDW).There are no studies comparing PD and PPDR for this *** To compare the safety,efficacy,and short-and long-term results of PD and PPDR in patients with *** A retrospective analysis of the clinical,radiologic,pathologic,and intra-and postoperative data of 84 patients with CDDW(2004-2020)and a comparison of the safety and efficacy of PD and *** Symptoms included abdominal pain(100%),weight loss(76%),vomiting(30%)and jaundice(18%)and data from computed tomography,magnetic resonance imaging,and endoUS led to the correct preoperative diagnosis in 98.8%of *** patients were treated conservatively with pancreaticoenterostomy(n=8),duodenum-preserving pancreatic head resection(n=6),PD(n=44)and PPDR(n=15)without *** gain was significantly higher after PD and PPDR and complete pain control was achieved significantly more often after PPDR(93%)and PD(84%)compared to the other treatment modalities(18%).new onset diabetes mellitus and severe exocrine insufficiency occurred after PD(31%and 14%),but not after *** PPDR has similar safety and better efficacy than PD in patients with CDDW and may be the optimal procedure for the isolated form of *** pure form of GP is a duodenal disease and PD may be an overtreatment for this *** detection of CDDW provides an opportunity for pancreas-preserving surgery.

关键词： Groove pancreatitis Cystic dystrophy of the duodenal wall Pancreaspreserving duodenectomy Pancreas-preserving duodenal resection Chronic pancreatitis Pancreatoduodenectomy

Peroral endoscopic myotomy in a pregnant woman diagnosed with mitochondrial disease:A case report

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World Journal of Gastrointestinal Endoscopy 2021年第5期13卷 155-160页

作者： Alexander A Smirnov Maya M Kiriltseva Mariya E Lyubchenko Vladimir D nazarov Anna V Botina aleksandr n Burakov Sergey V Lapin Department of Endoscopy Pavlov First Saint Petersburg State Medical UniversitySaint Petersburg 197022Russia Center for Molecular Medicine Pavlov First Saint Petersburg State Medical UniversitySaint Petersburg 197022Russia Department of Pathology Pavlov First Saint Petersburg State Medical UniversitySaint Petersburg 197022Russia

BACKGROUnD Achalasia is a primary esophageal motility disease characterized by impairment of normal esophageal peristalsis and absence of relaxation of the lower esophageal *** is can be a part of some genetic *** of the causes of gastrointestinal motility disorders,including achalasia,is mitochondrial *** SUMMARY We report about a pregnant woman with a history of symptoms associated with inherited mitochondrial disease,which was confirmed by genetic tests,and who was treated via peroral endoscopic *** Peroral endoscopic myotomy is possible treatment option for a pregnant woman with achalasia caused by mitochondrial disease.

关键词： Mitochondrial disease Pregnancy Esophagus Peroral endoscopic myotomy Achalasia Biopsy Case report

High-pressure torsion deformation process of bronze/niobium composite

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Transactions of nonferrous Metals Society of China 2019年第8期29卷 1689-1695页

作者： S. O. ROGACHEV S. A. nIKULIn V. M. KHATKEVICH R. V. SUnDEEV D. A. kozlov national University of Science and Technology “MISIS” Leninsky pr. 4 Moscow 119049 Russia Russian Technological University “MIREA” pr. Vernadskogo 78 Moscow 119454 Russia

The deformation process in the material volume under high-pressure torsion(HPT)was *** a model object for the observation of deformation process,we used a composite comprising a bronze matrix and niobium *** arrangements of the niobium filaments in the bronze matrix and their size have regular *** allows us to monitor and measure the displacement of the niobium filaments in the sample volume,which results from *** bronze/niobium composite samples were subjected to HPT at room temperature and 6 GPa,and the number of revolutions n=1/4,1/2,1,2,3 and *** was shown that HPT with revolution number of 1 leads to the 360° rotation of entire sample volume without sample *** deformational behavior during HPT can be expected for high-ductility metallic *** increase in the number of revolutions more than 2 leads to twisting the niobium filaments in the sample volume and the formation of 'vortex' multilayer *** mechanisms for the formation of such structures were discussed.

关键词： high-pressure torsion severe plastic deformation metal matrix composite vortex structure

THE InVESTIGATIOn OF KInETICS OF HIGH-TEMPERATURE STRUCTURE TRAnSFORMATIOn OF HOMOPHASES AnD HETEROPHASES MATERIALS

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Acta Metallurgica Sinica(English Letters) 2000年第2期13卷 551-556页

作者： M.D. Starostenkov, E. V.kozlov, O. V. Andruhova, n. V. Lomskikh, n.M. Gurova and A. V. Borissov 1) General Physics Department, ASTU, Lenin St. 46, Barnaul, 656099, Russia 2) Physics Department, TSABU, Solyanaya Sq., 2, Tomsk, 634003, Russia

The kinetics of internal boundaries relaxation: antiphase domain boundaries and interphase boundaries-in the conditions of high-temperature annealing and the structure transformations are investigated in homophase and heterophase systems. Homophase systems look like ordered binary alloy and include antiphase domain boundaries of various orientation. Clear components border on ordered alloy in heterophase systems and two processes take place simultaneously here-disordering of binary alloy and solution in ordered phase of clear component. Computer experiment is realized in the sphere of temperatures close to the temperature of order-disorder phase transition in the limits of two-dimensional model of atom diffusion at the vacant knots of crystal lattics.

关键词： computer simulation phase order-disorder transition antiphase boundary interphase boundary diffusion

A quantum-chemical model of the inhibition mechanismof viral DnA HIV-1 replication by Iodine complexcompounds

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natural Science 2011年第7期3卷 573-579页

作者： Gulnara A. Yuldasheva Georgii M. Zhidomirov aleksandr I. Ilin 不详

The interaction of molecular iodine with virus DnA nucleotide is studied by ab initio RHF/3-21G** method. Formation of the nucleoprotein complex of the HIV DnA, molecular iodine and the HIV-1 integrase co-factor is considered to cause the inhibition action of the integrase enzyme. Experimental data on the anti-HIV effect of the molecular iodine complex compounds and the results of calculations suggest that molecular iodine contained in iodine polymer complexes may be considered as a compound inhibiting the catalytic center of the integrase enzyme. Unlike the known integrase inhibitors, molecular iodine also changes the virus DnA structure and produces the n-I bond in the purine bases of adenosine and guanosine nucleotides.

关键词： HIV Integrase HIV Quantum-Chemical Method Ab Initio

Effectiveness of negative pressure wound therapy in complex surgical treatment of necrotizing fasciitis of the upper limb

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World Journal of Orthopedics 2024年第11期15卷 1015-1022页

作者： Konstantin V Lipatov Arthur Asatryan George Melkonyan aleksandr D Kazantcev Ekaterina I Solov’eva Denis V Krivikhin Irina V Gorbacheva Urii E Cherkasov Department of General Surgery Institute of Clinical Medicine named after N.V.SklifosovskySechenov First Moscow State Medical University(Sechenov University)Moscow 119021Russia Department of General Surgery Wound and Wound Infection SurgeryState Budgetary Institution“City Clinical Hospital named after S.S.Yudin of Moscow Healthcare Department”Moscow 115446Russia Department of General Surgery Physician of The Hospital for War Veterans No 3Moscow 129336Russia Department of General Surgery I.M.Sechenov First Moscow State Medical UniversityMoscow 119048Russia

BACKGROUnD necrotizing fasciitis(nF)of the upper extremities is a severe surgical pathology,and the incidence of this disease has been steadily increasing in recent *** treatment is accompanied by the formation of extensive wounds,which can be treated with significant *** recent years,negative pressure wound therapy(nPWT)has proven to be highly *** is also promising for the treatment of *** To explore the effectiveness of nPWT in the treatment of nF of the upper *** The results of the treatment of 36 patients with nF of the upper extremities in two groups(nPWT group and control group;2022−2023)were retrospectively *** the nPWT group,the nPWT method(120 mmHg;constant mode)was used after surgical *** number of vacuum-assisted dressings in patients ranged from 1 to 3,depending on the dynamics of the wound *** duration of fixation of one bandage was up to 2−3 *** the control group,conventional methods of local wound treatment were *** following indicators were analyzed:The treatment delay,the prevalence of inflammation,the microbial landscape,the number of debridements,the duration of wound preparation for surgical closure,and the nature of skin plastic *** Most patients experienced a significant treatment delay[4 d,interquartile range(IQR):2–7 d],which led to the spread of the pathological process to the forearm and *** most common pathogens were Staphylococcus aureus(14;38.9%)and Streptococcus pyogenes(22;61.1%).The average number of debridements per patient was 5(IQR:3–7),with no difference between *** average time to prepare wounds for surgical closure was 11±4 d in the nPWT group and 29±10 d(P=0.00001)in the control *** the nPWT group,the wounds were more often closed with local tissues(15;83.3%),and in the control group,split-thickness skin grafts were more often used(4;50%).COnCLUSIOn The predominant isolation of Staphylococcus aureus and/or Strep

关键词： necrotizing fasciitis Upper limb negative pressure wound therapy Vacuum-assisted closure Surgical treatment

Septic arthritis of the hand: From etiopathogenesis to surgical treatment

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World Journal of Orthopedics 2022年第11期13卷 993-1005页

作者： Konstantin V Lipatov Arthur Asatryan George Melkonyan aleksandr D Kazantcev Ekaterina I Solov’eva Irina V Gorbacheva Alexander S Vorotyntsev Andrey Y Emelyanov General Surgery Department Institute of Clinical Medicine named after N.V.SklifosovskySechenov First Moscow State Medical University(Sechenov University)Moscow 119021Russia General Surgery Department State Budgetary Institution“City Clinical Hospital named after S.S.Yudin of Moscow Healthcare Department”Moscow 115142Russia General Surgery Department The Hospital for War Veterans N3Moscow 129336Russia General Surgery Department I.M.Sechenov First Moscow State Medical UniversityMoscow 119991Russia

BACKGROUnD Septic arthritis of the hand,which is the second most common after damage of the knee joint,remains one of the leading causes of temporary *** inflammation can cause dysfunction of the joint,and in the most severe cases,the need for amputation of the finger may *** results of their treatment today,especially from a functional point of view,cannot be considered *** surgical treatment is extremely important in septic arthritis of the hand,as it helps to prevent cartilage destruction and the development of *** To explore the features of the course of septic arthritis of the hand as well as approaches to surgical treatment and its results,depending on the nature of the damage to the articular *** The results of the treatment of 170 patients with septic arthritis of the hand,which were treated in the period of 2020-2021,were *** of the interphalangeal and metacarpophalangeal joints(MCP)of fingers 1,2,and 3 was more often noted in 147(81.6%)*** most common cause of arthritis was a penetrating injury as a result of household trauma(101,59.4%),animal bite(30,17.6%),and clenched fist injury(15,8.8%).Septic arthritis with contiguous osteomyelitis was observed in 98(54.4%)*** treatment was completed with drainage and irrigation of the *** mobilization was used to restore *** patients with osteomyelitis,it was aimed at the formation of *** was not ***-term results of treatment were assessed in 142(83.5%)patients within 1 mo to 12 mo after discharge from the hospital[the median was 7 mo(IQR:4-9)].RESULTS The most commonly isolated organism was Staphylococcus aureus(35.3%).The median treatment delay in patients without osteomyelitis was 5 d(IQR:4-7);for septic arthritis with contiguous osteomyelitis,it was 14 d(IQR:5-21).Radiography for osteomyelitis within 2 wk was uninformative:41.2%of diagnoses.A single surgical treatment was

关键词： Septic arthritis Osteomyelitis Hand Surgical treatment neoarthrosis

Exploring van der Waals materials with high anisotropy:geometrical and optical approaches

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Light(Science & Applications) 2024年第4期13卷 645-653页

作者： aleksandr S.Slavich Georgy A.Ermolaev Mikhail K.Tatmyshevskiy Adilet n.Toksumakov Olga G.Matveeva Dmitriy V.Grudinin Kirill V.Voronin Arslan Mazitov Konstantin V.Kravtsov Alexander V.Syuy Dmitry M.Tsymbarenko Mikhail S.Mironov Sergey M.novikov Ivan Kruglov Davit A.Ghazaryan Andrey A.Vyshnevyy Aleksey V.Arsenin Valentyn S.Volkov Kostya S.novoselov Moscow Center for Advanced Studies Kulakova str.20Moscow 123592Russia. Emerging Technologies Research Center XPANCEOInternet CityEmmay TowerDubaiUnited Arab Emirates. Donostia International Physics Center(DIPC) Donostia/San-Sebastián 20018Spain. Institute of Materials Ecole Polytechnique Federale de Lausanne1015 LausanneSwitzerland. Department of Chemistry Lomonosov Moscow State UniversityMoscow 119991Russia. Laboratory of Advanced Functional Materials Yerevan State UniversityYerevan 0025Armenia. national Graphene Institute(nGI) University of ManchesterManchester M139PLUK. Department of Materials Science and Engineering National University of SingaporeSingapore 03-09 EASingapore. Institute for Functional Intelligent Materials National University of Singapore117544 SingaporeSingapore

The emergence of van der Waals(vdW)materials resulted in the discovery of their high optical,mechanical,and electronic anisotropic properties,immediately enabling countless novel phenomena and *** success inspired an intensive search for the highest possible anisotropic properties among vdW ***,the identification of the most promising among the huge family of vdW materials is a challenging quest requiring innovative ***,we suggest an easy-to-use method for such a survey based on the crystallographic geometrical perspective of vdW materials followed by their optical *** our approach,we found As2S3 as a highly anisotropic vdW *** demonstrates high in-plane optical anisotropy that is~20%larger than for rutile and over two times as large as calcite,high refractive index,and transparency in the visible range,overcoming the century-long record set by *** these benefits,As2S3 opens a pathway towards nextgeneration nanophotonics as demonstrated by an ultrathin true zero-order quarter-wave plate that combines classical and the Fabry–Pérot optical phase ***,our approach provides an effective and easy-to-use method to find vdW materials with the utmost anisotropic properties.

关键词： anisotropy anisotropic high