检索结果-南通市图书馆

Are eavesdroppers multimodal？ Sensory exploitation of floral signals by a non-native cockroach Blatta orientalis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Zoology 2011年第2期57卷 162-174页

作者： Rodrigo C. vERGARA alejandra TORRES-ARANEDA Diego A. vILLAGRA Robert A. RAGUSO Mary T. K. ARROYO Cristian A. vILLAGRA Instituto de Ecologfa y Biodiversidad IEB Universidad de Chile Santiago Chile Centro de Recursos Naturales y Medio Ambiente Departamento de Qufmica Facultad de Ciencias Universidad de Tarapaca Arica Chile Department of Neurobiology and Behavior Cornell University Ithaca NY 14853 USA Instituto de Entomologfa Universidad Metropolitana de Ciencias de la Educacion Casilla 147 SantiagoChile

The study of multi-modal communication has only recently been extended to innate and learned interactions between flowers and their animal visitors, and usually only to pollinators. Here we studied the relevance of floral scent and visual display of a night blooming, putatively hawkmoth-pollinated plantOenothera acaulis(Onagraceae) in the attraction of non-native cockroachesBlatta orientalis(Blattodea: Blattidae), which function as facultative floral larcenists in coastal habitats of central Chile. We experimentally decoupled visual (corolla) and olfactory (fragrance) stimuli by presenting paper corollas and green mesh bags, with or without a freshly-picked natural flower inside. We then contrasted the behavioral responses of roaches in these treatments with those to the natural combination of traits in actual flowers and their respective control treatments, measuring the roaches’ frequency of first visits, mean and total residence time spent in each treatment. The roaches primarily used olfactory cues when approachingO. acaulisflowers at two biologically relevant spatial scales. In addition, the presence of conspecific roaches had a strong influence on recruitment to the experimental arena, increasing the statistical differences among treatments. Our results suggest a primacy of floral fragrance over visual stimuli in the foraging responses ofB. orientalis. Olfactory cues were necessary and sufficient to attract the roaches, and the visual cues presented in our manipulations only marginally increased their attraction within a 20 cm diameter of the stimulus. The full spectrum of floral visitation behavior was not elicited by the artificial flowers, suggesting the need for additional tactile or contact chemosensory stimuli not provided by paper. Although the nitrogenous scent compounds that we found inO. acaulisflowers are almost exclusively found in hawkmoth-pollinated flowers, the attractiveness of these compounds to a non-native, facultative flower-visiting insect

关键词：蟑螂花香多式联运信号香味化合物窃听开发感官

Detection of Antinuclear Antibodies in Canine Serum by Immunoperoxidase in MDCK and Indirect Immunofluorescence in HEp2 Cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of veterinary Medicine 2023年第5期13卷 41-52页

作者： Guillermo valdivia Anda Edgar Guillermo valdivia Lara Ana Cristina Calderón Uribe alejandra Andrea Escobar Patiño Gloria Elena Lara Reyes Laboratorio de Patogenicidad Microbiana Unidad de Investigación Multidisciplinaria FESC UNAM México City México Departamento de Patología Universidad Complutense de Madrid Madrid Espa&#241a Laboratorio DIveT^® </sup> Estado de México México City México

Antinuclear antibodies are found in animals suffering from Systemic Lupus Erythematosus (SLE) and some other diseases, their presence in the blood is determined by antinuclear antibody (ANA) test using indirect immunofluorescence (IF) with HEp2 cells as a substrate. In this work, an immunoperoxidase (IP) assay was developed to evaluate the ANAs in canine sera, using canine kidney cell lines (MDCK) and compared with a commercial immunofluorescence test on Hep2 cells for this system, a fluoresceinated anti-canine Ig antibody was standardized. The study was performed on 50 sera from dogs submitted to the laboratory with different clinical diagnoses of autoimmune-associated diseases. The procedures on both cells were unified to perform comparisons of the reactions, direct sera or at different dilutions were added to a monolayer of permeabilized MDCK cells, followed by a peroxidized anti-canine IgG conjugate, and a substrate for the IP reaction. The same sera were tested on the commercial IF assay on Hep2 cell system. In 22/50 cases, the presence of LE cells in peripheral blood was determined. A high correlation was found in the detection of antinuclear antibodies between both cell lines and techniques, however there were differences in the reaction patterns in the nucleus and cytoplasm between cell lines. The diffuse nuclear pattern observed in MDCK cells was more related to the presence of high percentages of LE cells in peripheral blood. The differences found in the results were possibly associated with the presence of homologous antigens between the MDCK cells and the dog. In addition, the methodology and standardization for the use and interpretation of a reference serum was developed to unify the interpretation criteria in the laboratory.

关键词： Antinuclear Antibodies Immunoperoxidase in Marbin Darbin Canine Kidney (MDCK) SLE Associate Disease

Incidence, prevalence, and demographic characteristics of ocular cicatricial pemphigoid in Colombia: data from the National Health Registry 2009-2019

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2021年第11期14卷 1765-1770页

作者： Carlos Cifuentes-González Stefania Amaris-Martínez Juliana Reyes-Guanes Pilar Uribe-Reina alejandra de-la-Torre Neuroscience Research Group Escuela de Medicina y Ciencias de la SaludUniversidad del RosarioBogota 111221Colombia Escuela Barraquer Research Group Escuela Superior de Oftalmología del Instituto Barraquer de AméricaBogota 110111Colombia

AIM:To provide an epidemiological characterization of ocular cicatricial pemphigoid(OCP)in ***:We conducted a cross-sectional study using *** applied the specific code of the International Classification of Diseases for Ocular Pemphigoid,from 2009-2019 to estimate prevalence,incidence,and the demographic status of the disease in ***:The estimated average prevalence was 0.22 per 1000000 inhabitants,and the estimated average incidence was 0.24 per 1000000 *** a female predominance of 62.5%,and a male/female ratio of 1:*** group of patients diagnosed with the disease after the age of 80 presented the highest *** departments with the highest prevalence were Antioquia,Bogotá,and ***:There are important differences between worldwide and Colombian prevalence and incidence data,which may be related to genetic and epigenetic factors,and the possible underdiagnosis of the *** to the results,OCP is an extremely rare disease in ***,it is important to encourage awareness of the disease due to its devastating consequences.

关键词： ocular cicatricial pemphigoid epidemiology incidenee ophthalmology Colombia autoimmune diseases

Morphometrics confirms the conspecific between Blaptica dubia(Serville) and B. interior Hebard(Blattodea:Blaberidae)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Zoological Systematics 2019年第2期44卷 111-122页

作者： María Marta González alejandra del Carmen valverde Mónica Sandra Iglesias Francisco Antonio Crespo Laboratorio de Artrópodos Departamento de Biodiversidad y Biología Experimental Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires Pabellón Ⅱ Ciudad Universitaria Centro de diagnóstico e investigación en endemo-epidemias. Administración nacional de laboratorios e institutos de salud "Dr. Carlos G. Malbrán"

Blaptica dubia(Serville, 1838) and B. interior Hebard, 1921 were considered to be cryptic species. The characteristics originally proposed for their identification are not *** the relationship between the two species should be re-considered. As a comparative approach and to analyze intraspecific variability, morphological and morphometric methods were performed. Traditional and new characters such as wing shape and pronotum contour were utilized. We found significant differences between both species(p verlap of values. We did not find differences in the body measurements or in the shape and size of the pronotum between the species. The variability gradient does not allow an accurate identification of species neither with the male genitalia or the pronotal *** on the obtained results, B. interior Hebard 1921 is considered to be a junior synonym of B. dubia(Serville, 1838).

关键词： Cockroaches pronotum genitalia geometric morphometric analysis synonymy

Severe COvID-19 patients exhibit an ILC2 NKG2D^(+) population in their impaired ILC compartment

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2021年第2期18卷 484-486页

作者： alejandra Gomez-Cadena Laurie Spehner Marie Kroemer Myriam Ben Khelil Kevin Bouiller Grégory verdeil Sara Trabanelli Christophe Borg Romain Loyon Camilla Jandus Department of Pathology and Immunology University of GenevaGenevaSwitzerlandand Ludwig Institute for Cancer ResearchLausanneSwitzerland University of Bourgogne Franche-Comté INSERMEFS BFCUMR1098RIGHT Interactions Greffon-Hôte-Tumeur/Ingénierie Cellulaire et GéniqueF-25000BesançonFrance Department of Pharmacy University Hospital of BesançonF-25000BesançonFrance Department of Infectious Disease University Hospital of BesançonF-25000BesançonFrance UMR-CNRS 6249 Chrono-Environment UniversitéBourgogne Franche-ComtéF-25000BesançonFrance Department of Oncology UNIL-CHUVUniversity of Lausanne1066EpalingesSwitzerland Department of Medical Oncology University Hospital of BesançonF-25000BesançonFrance

Severe acute respiratory syndrome coronavirus 2(SARS-Cov-2)is responsible for the current COvID-19 disease *** some patients,the symptoms are mild,and a fraction of SARS-Cov-2-infected individuals develop severe illness with a high fatality rate due to lung damage and acute respiratory distress syndrome.1 Innate lymphoid cells(ILCs)are a recently identified type of effector immune cells that rapidly sense environmental stimuli and participate in early immune responses by promptly secreting large amounts of cytokines.2 The ILC2 subpopulation was shown to mediate Type 2 responses and to recruit eosinophils during viral lung infections upon the release of alarmins(e.g.,IL-33)by damaged epithelial cells.3,4,5 ILC2s were also shown to participate in the termination of inflammatory responses and tissue repair by amphiregulin *** addition,ILC2s are critical in the early phases of allergic lung inflammation,including that induced by the protease allergen papain.6 Based on the essential function of the papain-like protease PLpro in regulating SARS-Cov-27(Fig.1a)and the severe lung damage caused by this virus,we sought to investigate the potential involvement of ILC2s in immune responses to COvID-19.

关键词： impaired patients acute

vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2023年第6期18卷 1196-1202页

作者： Instituto de Salud Carlos III Irene villalón-García Suleva Povea-Cabello MónicaÁlvarez-Córdoba Marta Talaverón-Rey Juan MSuárez-Rivero alejandra Suárez-Carrillo Manuel Munuera-Cabeza Diana Reche-López Paula Cilleros-Holgado Rocío Piñero-Pérez JoséA.Sánchez-Alcázar Centro Andaluz de Biología del Desarrollo(CABD-CSIC-Universidad Pablo de Olavide de Sevilla) and Centro de Investigación Biomédica en Red:Enfermedades RarasInstituto de Salud Carlos IIISevillaSpain

Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases,such as Alzheimer’s,Parkinson’s,and Huntington’s diseases,or neurodegeneration with brain iron accumulation *** dysfunction,lipofuscin accumulation,autophagy disruption,and ferroptosis have been implicated as the critical pathomechanisms of lipid peroxidation and iron accumulation in these ***,the connection between lipid peroxidation and iron accumulation and the initial cause or consequence in neurodegeneration processes is *** this review,we have compiled the known mechanisms by which lipid peroxidation triggers iron accumulation and lipofuscin formation,and the effect of iron overload on lipid peroxidation and cellular *** vicious cycle established between both pathological alterations may lead to the development of ***,the investigation of these mechanisms is essential for exploring therapeutic strategies to restrict *** addition,we discuss the interplay between lipid peroxidation and iron accumulation in neurodegeneration,particularly in PLA2G6-associated neurodegeneration,a rare neurodegenerative disease with autosomal recessive inheritance,which belongs to the group of neurodegeneration with brain iron accumulation disorders.

关键词： 4-hidroxynonenal ferroptosis iron lipid peroxidation lipofuscin neurodegeneration neurodegeneration with brain iron accumulation oxidative stress PLA2G6-associated neurodegeneration

YKL40 expression in CD14^+ liver cells in acute and chronic injury

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第33期17卷 3830-3835页

作者： Oscar Pizano-Martínez Irinea Yaez-Sánchez Pilar Alatorre-Carranza alejandra Miranda-Díaz Pablo C Ortiz-Lazareno Trinidad García-Iglesias Adrian Daneri-Navarro Mónica vázquez-Del Mercado Mary Fafutis-Morris vidal Delgado-Rizo Department of Physiology CUCSUniversity of GuadalajaraGuadalajaraJalisco 44340México Division of Immunology Centro de Investigación Biomédica de OccidenteIMSS.GuadalajaraJalisco 44340México

AIM:To demonstrate that CD14 + cells are an important source of the growth factor YKL40 in acute and chronic liver ***:Rats were inoculated with one dose of CCl4 to induce acute *** biopsies were obtained at 0,6,12,24,48 and 72 *** chronic damage,CCl4 was administered three days per week for 6 or 8 *** samples were collected,and cellular populations were isolated by liver digestion and purified by cell ***40 mRNA and protein expression were evaluated by realtime polymerase chain reaction and western ***:Acute liver damage induced a rapid increase of YKL40 mRNA beginning at 12 *** peaked at 24 h,with a 26fold increase over basal *** 72 h however,YKL40 expression levels had nearly returned to control *** the other hand,chronic damage induced a sustained increase in YKL40 expression,with 7and 9fold higher levels at 6 and 8 wk,*** pattern of YKL40 expression in different subpopulations showed that CD14+cells,which include Kupffer cells,are a source of YKL40 after acute damage at 72 h[0.09 relative expression units(REU)]as well as after chronic injury at 6 wk(0.11 REU).Hepatocytes,in turn,accounted for 0.06 and 0.01 REU after 72 h(acute)or 6 wk(chronic),*** rest of the CD14cells(including T lymphocytes,B lymphocytes,natural killer and natural killer T cells) yielded 0.07 and 0.15 REU at 72 h and 6 wk,***40 protein expression in liver was detected at 72 h as well as 6 and 8 wk,with the highest expression relative to controls(11fold;P≤0.05)seen at 6 *** were stimulated by *** demonstrate that under these conditions,these cells showed maximum expression of YKL40 at 12 h,with Pver injury,with expression patterns similar to growth factors implicated in inflammationfibrogenesis.

关键词：急性肝损伤 CD14 肝细胞慢性细胞生长因子聚合酶链反应四氯化碳蛋白表达

Probabilistic Rainfall Thresholds for Landslide Episodes in the Sierra Norte De Puebla, Mexico

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural Resources 2017年第3期8卷 254-267页

作者： alejandra González Ernesto Caetano Institute of Geography National Autonomous University of Mexico Mexico City Mexico

The Sierra Norte de Puebla, Mexico, has a record of hundreds of mass removal processes triggered by rainfall, where the intensity and duration of the rain are the main mechanisms. In order to determine threshold values for precipitation as a cause of a landslide, the prior, marginal and conditional probabilities were calculated. A Bayesian method was used for one-dimensional (precipitation intensity) and two-dimensional (precipitation intensity and duration) analysis. This suggested a high probability of mass movement when the precipitation exceeds 60 mm within ten days. A proposed warning system is based on classes in which the threshold is exceeded.

关键词： Processes of Mass Removal Thresholds Probability Bayesian Method Sierra Norte De Puebla

Development of Moderate Intensity Focused Ultrasound(MIFU)for Ocular Drug Delivery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical Engineering Frontiers 2022年第1期3卷 240-247页

作者： alejandra Gonzalez-Calle Runze Li Isaac Asante Juan Carlos Martinez-Camarillo Stan Louie Qifa Zhou Mark S.Humayun USC Ginsburg Institute for Biomedical Therapeutics University of Southern CaliforniaLos Angeles CaliforniaUSA USC Roski Eye Institute Keck School of MedicineUniversity of Southern CaliforniaLos Angeles CaliforniaUSA Department of Biomedical Engineering University of Southern CaliforniaLos Angeles CaliforniaUSA USC School of Pharmacy University of Southern CaliforniaLos Angeles CaliforniaUSA

The purpose of this study is to develop a method for delivering antiinflammatory agents of high molecular weight(e.g.,Avastin)into the posterior segment that does not require injections into the eye(i.e.,intravitreal injections;IvT).Diseases affecting the posterior segment of the eye are currently treated with monthly to bimonthly intravitreal injections,which can predispose patients to severe albeit rare complications like endophthalmitis,retinal detachment,traumatic cataract,and/or increased *** this study,we show that one time moderate intensity focused ultrasound(MIFU)treatment can facilitate the penetration of large molecules across the scleral barrier,showing promising evidence that this is a viable method to deliver high molecular weight medications not *** validate the efficacy of the drug delivery system,IvT injections of vascular endothelial growth factor(vEGF)were used to create an animal model of *** creation of this model allowed us to test anti-vEGF medications and evaluate the efficacy of the *** vivo testing showed that animals treated with our MIFU device improved on the retinal tortuosity and clinical dilation compared to the control group while evaluating fluorescein angiogram(FA)Images.

关键词： viable Focus MIF