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International Journal of Ophthalmology(English edition) 2022年第6期15卷 990-996页

作者： valeria Becerril-Ledezma Daniela Alvarez-Ascencio Clarisa Esther del Hierro-Gutiérrez alejandra Hernandez-Oteyza Jesús Jiménez-Román Association to Prevent Blindness in Mexico Private Assistance Institution(APEC)Mexico City 04030Mexico

AIM: To assess and compare knowledge and awareness of glaucoma in subjects with and without glaucoma diagnosis attending an Ophthalmology Referral ***: This cross-sectional study was conducted at Asociación Para Evitar la Ceguera in Mexico City, using a questionnaire formulated by a group of experts following the Delphi panel rules, and pre-tested in a pilot *** questionnaire was applied and compared between:glaucoma patients, relatives of glaucoma patients and patients without glaucoma. Socio-demographic data was collected to assess correlation with the level of knowledge using Logistic regression models, estimating the odds ratios(OR), 95% confidence intervals, and Pves of patients with glaucoma. Two hundred and ninety-one(73.9%) participants were aware of the term “glaucoma”.Regarding knowledge 46.7% had moderate knowledge,37.8% had poor knowledge, and 15.5% good ***, relatives of glaucoma patients had the highest scores, and patients without glaucoma got the lowest scores. A positive correlation was found between better knowledge and frequent ophthalmological examinations OR 2.24(P=0.02), higher education level OR 4.17(P=0.00) and having a family member with glaucoma OR 3.28(P=0.00).CONCLUSION: Awareness and knowledge of glaucoma in subjects attending an Ophthalmology Referral Center is predominantly moderate or poor. This has important implications regarding attitudes that can result in lack of follow up in ophthalmological care.

关键词： glaucoma awareness knowledge vision loss treatment

Thought Provokers, Insurgent Before Emergency --Technological Art as Awareness-Raising Agent of the Emancipated Spectator

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Journal of Literature and Art Studies 2016年第8期6卷 929-936页

作者： alejandra Elena Marinaro Romina Alicia Flores School of Communication and Multimedia Design Universidad Maim6nides Buenos Aires Argentina

This paper analyzes the impact of technological art as an agent for raising awareness in artwork spectators of ecological-environmental issues. It addresses the evolution in the conception of the artistic fact related to science, and attempts to define the spectator＇s new role. The present document will look into the science, an and technology triad as a means to communicate issues our planet is facing through scientific dissemination focusing on the bio-art avenue for collaboration. Finally, we will outline our concept of an as a revolutionary and thoughtful form poured through our works as artistic collective expressions.

关键词： bio-art science technology interactive installations interactive design education digital art creativity

The effects of soil properties, cropping systems and geographic location on soil prokaryotic communities in four maize production regions across China

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Journal of Integrative Agriculture 2022年第7期21卷 2145-2157页

作者： TIAN Xue-liang LIU Jia-jia LIU Quan-cheng XIA Xin-yao PENG Yong alejandra I.HUERTA YAN Jian-bing LI Hui LIU Wen-de State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193P.R.China Henan Engineering Research Center of Biological Pesticide&Fertilizer Development and Synergistic Application Henan Institute of Science and TechnologyXinxiang 453003P.R.China School of Biological Science and Technology University of JinanJinan 250022P.R.China National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070P.R.China Department of Entomology and Plant Pathology North Carolina State UniversityRaleigh 27606USA

The diversity of prokaryotic communities in soil is shaped by both biotic and abiotic ***,little is known about the major factors shaping soil prokaryotic communities at a large scale in *** this end,we undertook a study to investigate the impact of maize production cropping systems,soil properties and geographic location(latitude and longitude)on soil prokaryotic communities using metagenomic techniques,across four distinct maize production regions in *** all study sites,the dominant prokaryotes in soil were Alphaproteobacteria,Gammaproteobacteria,Betaproteobacteria,Gemmatimonadetes,Acidobacteria,and ***-metric multidimensional scaling revealed that prokaryotic communities clustered into the respective maize cropping systems in which they *** analysis(RDA)showed that soil properties especially pH,geographic location and cropping system jointly determined the diversity of the prokaryotic *** functional genes of soil prokaryotes from these samples were chiefly influenced by latitude,soil pH and cropping system,as revealed by RDA *** abundance of genes in some metabolic pathways,such as genes involved in microbe–microbe interactions,degradation of aromatic compounds,carbon fixation pathways in prokaryotes and microbial metabolism were markedly different across the four maize production *** study indicated that the combination of soil pH,cropping system and geographic location significantly influenced the prokaryotic community and the functional genes of these *** work contributes to a deeper understanding of the composition and function of the soil prokaryotic community across large-scale production systems such as maize.

关键词： metagenome cropping system maize soil prokaryotes

Polymer and Surfactant-Polymer Emulsion Comparative Behavior Analysis Pre and Post Flooding through Porous Medium

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Polymer and Surfactant-Polymer Emulsion Comparative Behavior...

作者：兰婷婷（Rossmir alejandra Mujica Escalona）中国石油大学（北京）

学位级别：硕士

聚合物以及复合驱过程中的乳化现象对提高采收率起到重要作用,尽管付出了很多的努力,但是对于这些流体,尤其是乳状液,在孔隙中的详细流动机理仍然不清晰。本次研究将关注点放在油包水型乳状液和聚合物溶液上,研究在室内岩心典型驱替过... 详细信息

聚合物以及复合驱过程中的乳化现象对提高采收率起到重要作用,尽管付出了很多的努力,但是对于这些流体,尤其是乳状液,在孔隙中的详细流动机理仍然不清晰。本次研究将关注点放在油包水型乳状液和聚合物溶液上,研究在室内岩心典型驱替过程条件下化学体系性质及流动状态的变化,包括乳状液流动压力,粒径分布,流变性以及不同注入量下乳状液的微观形态。同时配置与乳状液粘度相近的聚合物,比较它们在多孔介质中流动规律的差异。结果表明在流经孔隙介质之后,乳状液的性质相较于聚合物彻底发生了改变了。压力方面,聚合物在两种流速条件下(0.2mL/min和0.4mL/min)的压力很稳定,但是乳状液的压力并不稳定,8个小时后还是会有快速的变化。乳状液粒径在4个Pv后变小,仍然保持乳化,粘度增加。聚合物始终保持的稳定的流变性。综上所述,乳状液和聚合物相比,在多孔介质中流动时仍具有不稳定性,但仍是目前提高采收率的主要方法。

关键词：乳状液聚合物相变行为粒径流变性

Update on the applications and limitations of alpha-fetoprotein for hepatocellular carcinoma

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World Journal of Gastroenterology 2022年第2期28卷 216-229页

作者： Hira Hanif Mukarram Jamat Ali Ammu T Susheela Iman Waheed Khan Maria alejandra Luna-Cuadros Muzammil Muhammad Khan Daryl Tan-Yeung Lau Department of Medicine Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215United States Internal Medicine Loyola MacNeal HospitalBerwynPA 60402United States

Alpha-fetoprotein(AFP)is an oncofetal glycoprotein that has been used as a tumor marker for hepatocellular carcinoma(HCC)in combination with ultrasound and other imaging *** utility is limited because of both low sensitivity and specificity,and discrepancies among the different methods of ***,its accuracy varies according to patient characteristics and the AFP cut-off values *** of AFP with novel biomarkers such as AFP-L3,Golgi specific membrane protein(GP73)and des-gamma-carboxyprothrombin significantly improved its accuracy in detecting *** AFP level could also signify severity of hepatic destruction and subsequent regeneration and is commonly observed in patients with acute and chronic liver conditions and *** and other non-hepatic disorders can also cause AFP elevation.

关键词： Alpha-fetoprotein Hepatocellular carcinoma Alpha-fetoprotein-L3 Cirrhosis Tumor markers Hereditary persistence of alpha-fetoprotein

The Pedagogic Capacity of Architecture the Macro Project University Citadel—University of Atlántico Barranquilla—Colombia

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Open Journal of Civil Engineering 2018年第2期8卷 129-141页

作者： Carlos Bell Lemus Mayra alejandra Rivero Bueno National University of Colombia Bogot&aacute D.C. Colombia University of Atlá ntico Barranquilla Colombia

Urban agenda nowadays puts pedestrians as the axis of urban design, and pedestrians are the most important thing in the city. The architect takes that idea and applies it in the project, and he focuses on prioritizing the pedestrian over the cars. Public spaces filled with green zones are a main element, water treatment is a design determinant, buildings use natural illumination as much as possible and culture and arts are reinforced through new scenarios.

关键词： University Project Urban Design Pedestrian Public Architecture

Evaluation of the Performance of Galvanized Steel Support in Construction of Living Wall Systems

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Open Journal of Civil Engineering 2016年第4期6卷 566-576页

作者： Fernando B. Mainier Maria alejandra Rico Pérez Leandro v. Pontual Ana Lucia Torres Seroa da Motta Escola de Engenharia Universidade Federal Fluminense Niterói Brazil

Currently, Living Wall Systems (LWSs) are assuming great importance in the built environment, due to environmental and aesthetic advantages, as well as the use of urban residual space and underutilized surfaces of buildings. However, the maintenance and the durability of the materials used have been a challenge for architects and professionals in the field. The aim of this paper is to evaluate the anti-corrosion performance of a steel framing profile, galvanized carbon steel (55% Al-Zn), a sustainable material with easy assembly, to apply LWS in the hot and humid tropical climate of Niterói (Rio de Janeiro, Brazil). In order to create the conditions of the tests, “X” cut were made in Al-Zn coating, sanding, and application of epoxy and glass fiber-reinforced polyester. After the experiments that lasted four months, the 55% Al-Zn coating was analyzed using Scanning Electron Microscope (SEM) and energy dispersive X-ray spectroscopy (EDS). The results of the tests were promising for the use of this galvanized steel for application as a support for green vertical facades. 55% Al-Zn coatings are recommended for marine atmospheres due to their good anti-corrosion performance.

关键词： Living Wall System (LWS) 55% Al-Zn Coating Steel Framing Galvanized Steel Corrosion

Assessment of drug-induced hepatotoxicity in clinical practice: A challenge for gastroenterologists

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World Journal of Gastroenterology 2007年第3期13卷 329-340页

作者： Raúl J Andrade Mercedes Robles alejandra Fernández-Castaer Susana López-Ortega M Carmen López-vega M Isabel Lucena Liver Unit Gastroenterology Service "Virgen de la Victoria" University Hospital and School of Medicine Mlaga Spain Clinical Pharmacology Service "Virgen de la Victoria" University Hospital and School of Medicine Mlaga Spain

Currently, pharmaceutical preparations are serious contributors to liver disease; hepatotoxicity ranking as the most frequent cause for acute liver failure and post-commercialization regulatory decisions. The diagnosis of hepatotoxicity remains a difficult task because of the lack of reliable markers for use in general clinical practice. To incriminate any given drug in an episode of liver dysfunction is a step-by-step process that requires a high degree of suspicion, compatible chronology, awareness of the drug’s hepatotoxic potential, the exclusion of alternative causes of liver damage and the ability to detect the presence of subtle data that favors a toxic etiology. This process is time-consuming and the final result is frequently inaccurate. Diagnostic algorithms may add consistency to the diagnostic process by translating the suspicion into a quantitative score. Such scales are useful since they provide a framework that emphasizes the features that merit attention in cases of suspected hepatic adverse reaction as well. Current efforts in collecting bona fide cases of drug-induced hepatotoxicity will make refinements of existing scales feasible. It is now relatively easy to accommodate relevant data within the scoring system and to delete low-impact items. Efforts should also be directed toward the development of an abridged instrument for use in evaluating suspected drug-induced hepatotoxicity at the very beginning of the diagnosis and treatment process when clinical decisions need to be made. The instrument chosen would enable a confident diagnosis to be made on admission of the patient and treatment to be fine-tuned as further information is collected.

关键词： Drug-induced hepatotoxicity Causality assessment Diagnostic algorithms Clinical scales

Allicin neuroprotective effect during oxidative/inflammatory injury involves AT1-Hsp70-iNOS counterbalance axis

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BIOCELL 2020年第4期44卷 671-681页

作者： LUCIANA MAZZEI MARÍA BELÉN RUIZ-ROSO NATALIA DE LAS HERAS SANDRA BALLESTEROS CAROLINA TORRESPALAZZOLO LEÓN FERDER alejandra BEATRIZ CAMARGO WALTER MANUCHA Instituto de Medicina y Biología Experimental de Cuyo(IMBECU) Consejo Nacional de Investigaciones Científicas y Tecnológicas(CONICET)Mendoza5500Argentina Área de Farmacología Departamento de PatologíaFacultad de Ciencias MédicasUniversidad Nacional de Cuyo Centro UniversitarioMendoza5500Argentina Departamento de Fisiología Facultad de MedicinaUniversidad ComplutenseMadrid34523España IBAM Universidad Nacional de CuyoCONICETFacultad de Ciencias AgrariasMendozaM5528AHBArgentina Department of Pediatrics Nephrology DivisionMiller School of MedicineUniversity of MiamiMiami33012USA

The ancestral cultures have described many therapeutic properties of garlic,therefore,it is of central interest to elucidate the molecular basis explaining this millenary empirical ***,it has been demonstrated a neuroprotective effect of allicin–a phytochemical present in garlic-linked to oxidative-inflammatory *** improved neuronal injury by heat shock protein 70(Hsp70)and inducible nitric oxide synthase(iNOS)***,allicin exerts renal protection involving a possible angiotensin type 1 receptor(AT1)*** connection,AT1 overexpression has been recognized as a central deleterious factor in many brain ***,there are no studies that evaluate AT1-Hsp70-iNOS interaction as a mechanism linked to ***,our central aim is to evaluate if the allicin protective effect is associated with an AT1-Hsp70-iNOS counterbalance *** this study,a murine microglial cell line(Bv-2)was injured with lipopolysaccharides and treated or not with ***,it was evaluated cell viability,proinflammatory cytokine levels,cellular oxidative stress,iNOS,Hsp70,and AT1 protein expression(cellular and mitochondrial fractions),nitrite levels,and protein-protein *** results demonstrated that allicin could prevent neuronal injury due to a reduction in oxidative stress and inflammatory status mediated by an AT1-Hsp70-iNOS counterbalance axis linked to direct protein-protein interaction.

关键词： Allicin neuroinflammation Bv-2 cells AT1 receptors iNOS Hsp70

Finite Element Structural Analysis of Buried Pipelines

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Modern Mechanical Engineering 2022年第2期12卷 27-44页

作者： Casanova-del-Angel Francisco Córdova-Castillo alejandra Escuela Superior de Ingeniería y Arquitectura UP ALM SEPI of the Instituto Politécnico Nacional Mexico City Mexico

This document uses previous results (which we call the first stage), for the development of a computer model based on finite elements under the FEAP programmer, to carry out a structural analysis of a pipeline. For this purpose, we used environmental variables that we believe influence the failure of buried pipelines such as the internal pressure of fluid, the type of support used, the temperature at which the pipelines work, the type of soil and the stiffness of the soil acting on it. Once the model was finalized, analyses were made with each of the variables separately and combined to observe the behavior of the pipeline, finding the most unfavorable case that indicates the main causes that led to its failure.

关键词： Duct Finite Element Buried Pipeline Material Creep Thermal Conditions Soil Springs