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胰腺导管腺癌放射学报告模板:腹部放射协会和美国胰腺协会的共识声明

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影像诊断与介入放射学 2014年第4期23卷 350-357页

作者： Mahmoud M.Al-Hawary Isaac R.Francis Suresh T.Chari Elliot K.Fishman David M.Hough David S.Lu Michael Macari alec j.megibow Frank H.Miller Dushyant V.Sahani Diane M.Simeone 黄翔孙灿辉东莞市人民医院放射科广东东莞523059 中山大学附属第一医院医学影像科广东广州510080

胰腺导管腺癌(PDA)是一种具有侵袭性、死亡率高的恶性肿瘤。在肿瘤分期时,通过影像学分析,合理判定肿瘤的范围,是患者治疗措施中最重要的步骤之一。考虑到不同医生在专业知识水平和疾病严重程度的判定有所差异,以及在放射学检查时经常... 详细信息

胰腺导管腺癌(PDA)是一种具有侵袭性、死亡率高的恶性肿瘤。在肿瘤分期时,通过影像学分析,合理判定肿瘤的范围,是患者治疗措施中最重要的步骤之一。考虑到不同医生在专业知识水平和疾病严重程度的判定有所差异,以及在放射学检查时经常缺乏相关影像学表现的完整报道,有必要采用标准化的影像学报告模板以及大家一致接受和认可的胰腺实性肿瘤术语。在腹部放射协会和美国胰腺协会的共同资助下,胰腺导管腺癌(PDA)多机构专家组(包括放射学专家、胃肠病学和肝胆胰外科学专家)共同发起了一份描述标准化报告模板的共识声明。采用这种标准化的影像学报告模板将能改进PDA患者的治疗决策过程,并可通过提供一份完整、相关、精准的疾病分期报告以优化治疗方案。通过对可行手术切除的患者恰当、一致的分期,标准化报告模板有助于促进临床和科研实验设计,从而实现在不同机构之间的实验结果的比较。

关键词：胰腺导管腺癌放射学检查报告模板协会美国腹部影像学分析疾病严重程度

Superhydrophobic modification of cellulose and cotton textiles:Methodologies and applications

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journal of Bioresources and Bioproducts 2020年第1期5卷 1-15页

作者： David W.Wei Haiying Wei alec C.Gauthier junlong Song Yongcan jin Huining Xiao Department of Chemical Engineering University of New BrunswickFrederictonNB E3B 5A3Canada joint International Research Lab of Lignocellulosic Functional Materials and Provincial Key Lab of Pulp and Paper Sci&Tech.Nanjing Forestry University Nanjing 210037China

Superhydrophobic cellulose-based products have immense potential in many industries where plastics and other polymers with hydrophobic properties are *** cellulose-based plastic is inherently biodegradable,renewable and *** a suitable replace-ment of plastics is highly desired since plastics has become an environmental *** its inherent hydrophilicity,cellulose has unparalleled advantages as a substrate for the produc-tion of superhydrophobic materials which has been widely used in self-cleaning,self-healing,oil and water separation,electromagnetic interference shielding,*** review includes a compre-hensive survey of the progress achieved so far in the production of super-hydrophobic materials based on cellulose and fiber *** methodologies and applications of superhydrophobic-modified cellulose and fiber networks are ***,presented herein is targeting on summarizing some of the aspects that are critical to advance this evolving field of science which may provide new ideas for the developing and exploring of superhydrophobic and green-based materials.

关键词： Cellulose Superhydrophobic modification Cotton textile Methodologies Applications

The evolution of clastic sedimentology

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Episodes 2006年第1期29卷 72-73页

作者： Hakuyu Okada alec j. Kenyon-Smith David Oldroyd 不详 School of History and Philosophy of Science The University of New South Wales Sydney 2052 AUSTRALIA

This valuable book was first published in japanese in 2002, under the title Sedimentology： a way to the new discipline of earth sciences. Given the problems that nearly all non-japanese people have in reading japanese, its translation into English in an expanded form, accomplished with the help of Professor Kenyon-Smith, is exceedingly welcome, given that it is the first book to provide a history of sedimentology. I should say at the outset that the translation is firstrate, being a model of clarity that puts many modern English-language texts to shame. The book is also copiously illustrated, including many photo-portraits of persons previously only known to me by name or through their writings.

关键词：《沉积学》地质环境书刊评价沉积学学科建设

Mixed iridium-nickel oxides supported on antimony-doped tin oxide as highly efficient and stable acidic oxygen evolution catalysts

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Materials Futures

Materials Futures 2024年第1期3卷 165-180页

作者： jonathan Ruiz Esquius alec P LaGrow Haiyan jin Zhipeng Yu Ana Araujo Rita Marques Adélio Mendes Lifeng Liu Clean Energy Cluster International Iberian Nanotechnology LaboratoryAv.Mestre JoséVeigaBraga 4715-330Portugal Carbon Science and Technology Institute INCAR-CSICFrancisco Pintado Fe 26Oviedo 33011Spain Scientific Imaging Section Okinawa Institute of Science and Technology Graduate UniversityKunigami-gunOkinawa 904-0412Japan Songshan Lake Materials Laboratory Dongguan 523808People’s Republic of China Laboratory for Process Engineering EnvironmentBiotechnology and EnergyFaculty of EngineeringUniversity of PortoRua Dr Roberto FriasPorto 4200-465Portugal Associate Laboratory in Chemical Engineering Faculty of EngineeringUniversity of PortoRua Dr Roberto FriasPorto 4200-465Portugal.

Proton exchange membrane(PEM)water electrolysis represents a promising technology for green hydrogen production,but its widespread deployment is greatly hindered by the indispensable usage of platinum group metal catalysts,especially iridium(Ir)based materials for the energy-demanding oxygen evolution reaction(OER).Herein,we report a new sequential precipitation approach to the synthesis of mixed Ir-nickel(Ni)oxy-hydroxide supported on antimony-doped tin oxide(ATO)nanoparticles(IrNiyO_(x)/ATO,20 wt.%(Ir+Ni),y=0,1,2,and 3),aiming to reduce the utilisation of scarce and precious Ir while maintaining its good acidic OER *** tested in strongly acidic electrolyte(0.1 M HClO_(4)),the optimised IrNi1Ox/ATO shows a mass activity of 1.0 mAµgIr^(−1) and a large turnover frequency of 123 s^(−1) at an overpotential of 350 mV,as well as a comparatively small Tafel slope of 50 mV dec^(−1),better than the IrOx/ATO control,particularly with a markedly reduced Ir loading of only 19.7µgIr cm^(−2).Importantly,IrNi1O_(x)/ATO also exhibits substantially better catalytic stability than other reference catalysts,able to continuously catalyse acidic OER at 10 mA cm^(−2) for 15 h without obvious *** in-situ synchrotron-based x-ray absorption spectroscopy confirmed that the Ir^(3+)/Ir^(4+)species are the active sites for the acidic ***,the performance of IrNi1Ox/ATO was also preliminarily evaluated in a membrane electrode assembly,which shows better activity and stability than other reference *** IrNi1Ox/ATO reported in this work is a promising alternative to commercial IrO_(2) based catalysts for PEM electrolysis.

关键词： mixed oxides oxygen evolution reaction polymer electrolyte membrane antimony doped tin oxide membrane electrode assembly

Percutaneous coronary intervention of totally occluded coronary venous bypass grafts:An exercise in futility?

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World journal of Cardiology 2021年第9期13卷 493-502页

作者： Evan W Nardone Brandon M Madsen Melissa M McCarey David L Fischman Nicholas j Ruggiero Paul Walinsky alec Vishnevsky Michael P Savage Department of Medicine Thomas Jefferson UniversityPhiladelphiaPA 19107United States Department of Anesthesiology Medstar Georgetown University HospitalWashingtonDC 20007United States jefferson Clinical Research Institue Thomas Jefferson UniversityPhiladelphiaPA 19107United States

BACKGROUND Percutaneous coronary intervention(PCI)of diseased saphenous vein grafts(SVG)continues to pose a clinical *** PCI guidelines give a class III recommendation against performing PCI on chronically occluded ***,contemporary outcomes after SVG intervention have incrementally improved with distal protection devices,intracoronary vasodilators,drug-eluting stents,and prolonged dual antiplatelet *** To reassess the procedural and long-term outcomes of PCI for totally occluded SVG with contemporary *** This was a retrospective observational study conducted at a single university *** study population consisted of 35 consecutive patients undergoing PCI of totally occluded ***-procedure dual antiplatelet therapy was continued for a minimum of one year and aspirin was continued *** outcomes were assessed at a mean follow-up of 1221±1038 *** primary outcome was freedom from a major adverse cardiac event(MACE)defined as the occurrence of any of the following:death,myocardial infarction,stroke,repeat bypass surgery,repeat PCI,or graft *** The study group included 29 men and 6 women with a mean age of 69±12 *** was present in 14(40%)*** patients had Canadian Heart Classification class III or IV *** presentation was an acute coronary syndrome in 34(97%)*** SVG age was 12±5 *** duration of occlusion was acute(24 h to 30 d)in 26%,and late(>30 d)in 40%.PCI was initially successful in 29/35 SVG occlusions(83%).Total stent length was 52±35 *** complications of distal embolization or no-reflow occurred in 6(17%)*** longer term follow-up,MACE-free survival was only 30%at 3 years and 17%at 5 *** PCI of totally occluded SVG can be performed with a high procedural success ***,its clinical utility remains limited by poor follow-up outcomes.

关键词： Coronary artery bypass grafting Coronary stents Chronic total occlusion Percutaneous coronary intervention Restenosis Saphenous vein grafts

ADAM8 inactivation retards intervertebral disc degeneration in mice

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Genes & Diseases 2024年第3期11卷 91-94页

作者： Zuozhen Tian Frances S.Shofer Mingyue Fan alec Z.Sandroni Lutian Yao Lin Han Ling Qin Motomi Enomoto-lwamoto Yejia Zhang Department of Physical Medicine&Rehabilitation Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA19146USA Department of Emergency Medicine Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA 19104USA Department of Orthopedic Surgery Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPA 19104USA School of Biomedical Engineering Science&Health SystemsDrexel UniversityPhiladelphiaPA 19104USA Department of Orthopedics/Sports Medicine and joint Surgery the First Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Orthopedics University of Maryland School ofMedicineBaltimoreMD21201USA Section of Rehabilitation Medicine Corporal Michael J.Crescenz Veterans Affairs Medical CenterPhiladelphiaPA 19104USA

ADAM8 has been identified as the fibronectin-cleaving enzyme in human degenerative intervertebral disc(IVD)tissues.^(1)Increase of the active form of ADAM8 and its cleavage product,fibronectin fragment,correlated with an increased degree of IVD degeneration.1 Furthermore,fibronectin fragments have been shown to accelerate the progression of IVD degeneration.^(2)These findings suggest that ADAM8 may play a role in degenerative disc disease,a clinical problem with tremendous socioeconomic burdens in the United States.

关键词： ADAM8 degeneration intervertebral

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问题与答案——改善放射性废物管理

国际原子能机构通报 2000年第3期42卷 19-20页

作者： alec j.BAER 国际核安全咨询组

国际核安全咨询组(INSAG)已经提出适用于任何未来工业活动的三项一般原则。在1999年报告《辐射源安全管理:原则与战略》(INSAG-11)中对这些原则进行了阐述。它们是:在一种活动的整个寿期循环中,好处应该胜过危险。

关键词：放射性废物管理安全管理核安全辐射源原则未来工业咨询可持续发展核电厂辐射安全

凝血因子Ⅷ C2结构域表达载体的构建及其在真核细胞NIH3T3中的表达

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吉林大学学报（医学版） 2005年第1期31卷 35-38,63页

作者：刘晓冬马淑梅 LANG Glen SEHON alec 吉林大学公共卫生学院卫生部放射生物学重点实验室吉林长春130021 加拿大曼尼拖巴大学医学院免疫系

目的 :构建人凝血因子 F 中具有免疫活性的 C2结构域表达载体并通过真核宿主细胞表达出多肽。方法 :从 HEK2 93细胞提取总 RNA,经 RT- PCR扩增获得目的片段。将该片段与信号肽共同构建在同一表达载体 ,并在 NIH 3T3细胞中表达 ,Western ... 详细信息

目的 :构建人凝血因子 F 中具有免疫活性的 C2结构域表达载体并通过真核宿主细胞表达出多肽。方法 :从 HEK2 93细胞提取总 RNA,经 RT- PCR扩增获得目的片段。将该片段与信号肽共同构建在同一表达载体 ,并在 NIH 3T3细胞中表达 ,Western blotting检测。结果 :经限制性酶切鉴定和测序分析证实 ,采用 RT- PCR成功地完成 F - C2 c DNA的扩增和表达载体的构建 ,重组载体转染进入 NIH 3T3细胞后 ,经检测培养上清中的蛋白成分证实 ,成功地表达出 F - C2结构域多肽。结论 :重组表达载体的构建是表达出分泌型 F C2多肽的一种可行的方法。

关键词：因子Ⅷ C2结构域逆转录聚合酶链反应基因重组

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现代底部填充方法的替代范例

现代表面贴装资讯 2006年第6期5卷 13-19页

作者： alec j.Babiarz 王建国（编译）不详宁波波导有限公司

新的底部填充方法采用了喷射技术，它使得采用更多的倒装晶片级高密封装成为了可能。与传统的针筒式施胶方法相比，喷射型底部填料与其他半导体封装流体一样，是粘合剂应用方法的一个替代典范。在过去，经常依靠各种各样的泵来输送流体... 详细信息

新的底部填充方法采用了喷射技术，它使得采用更多的倒装晶片级高密封装成为了可能。与传统的针筒式施胶方法相比，喷射型底部填料与其他半导体封装流体一样，是粘合剂应用方法的一个替代典范。在过去，经常依靠各种各样的泵来输送流体，他们的共同点都是把流体从针管挤压出来。喷射式方法放弃了针管，从而解决了与针管相关的所有问题，并开创了新的应用粘结剂的技术方法。同时，如果封装设计者乐于考虑不同的封装设计方法，他们可以参考关于大型芯片底部填充的新理念一如果需要的话可以采用零宽度边角。本论文将讨论关于喷射式毛细管作用底部填充方法和无流动底部填充方法的理论和过程，它是一项新的最小化填充时间的大型芯片底部填充方法，本论文还将回顾底部填充的基本原理。

关键词：喷射底部填充输送倒装