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Quality and readability of online information res.urces.on ins.mnia

Frontiers.of Medicine 2017年第3期11卷 423-431页

作者： Yan Ma albert C. Yang Ying Duan Ming Dong albert s. yeung Divis.on of Interdis.iplinary Medicine and Biotechnology Department of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA 02215 USA s.eep Medicine Center Airforee General Hospital Beijing 100142 China IBM Software Development Lab Littleton MA 01460 USA Depres.ion Clinical and Res.arch Program Massachusetts General Hospital Harvard Medical School Boston MA 02114 USA

The internet is.a major s.urce for health information. An increas.ng number of people, including patients.with ins.mnia, s.arch for remedies.online; however, little is.known about the quality of s.ch information. This.s.udy aimed to evaluate the quality and readability of ins.mnia-related online information. Google was.us.d as.the s.arch engine, and the top webs.tes.on ins.mnia that met the inclus.on criteria were evaluated for quality and readability. The analyzed webs.tes.belonged to nonprofit, commercial, or academic organizations.and ins.itutions.s.ch as.hos.itals.and univers.ties. Ins.mnia-related webs.tes.typically included definitions.（85%）, caus.s.and ris. factors.（100%）, s.mptoms.（95%）, and treatment options.（90%）. Cognitive behavioral therapy for ins.mnia （CBT-I） was.the mos. commonly recommended approach for ins.mnia treatment, and s.eep drugs.are frequently mentioned. The overall quality of the webs.tes.on ins.mnia is.moderate, but all the content exceeded the recommended reading eas. levels. Concerns.that mus. be addres.ed to increas. the quality and trus.worthines. of online health information include s.aring metadata, s.ch as.authors.ip, time of creation and las. update, and conflicts.of interes.; providing evidence for reliability; and increas.ng the readability for a layman audience.

关键词： ins.mnia intemet readability information quality health literacy cognitive behavioral therapy treatment

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Enhanced electrokinetic remediation of cadmium-contaminated natural clay us.ng organophos.honates.in comparis.n with EDTA

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Chines. Journal of Chemical Engineering 2018年第5期26卷 1152-1159页

作者： Yingying Gu albert T. yeung Hongjiang Li Department of Environmental and s.fety Engineering China University of Petroleum (East China) Qingdao 266580 China Department of Engineering The Univers.ty of Hong Kong Pokfulam Road Hong Kong China Qingdao Water Group Co. Ltd. Qingdao 266002 China College of Mining Civil Engineering Taiyuan University of Technology Taiyuan 030024 China

s.il contamination by metals.is.a worldwide environmental problem. Electrokinetic extraction is.a promis.ng technology for in-s.tu remediation of contaminated s.ils.of low hydraulic permeability. However, the extraction of metals.is.us.ally hindered by the high buffer capacity of natural s.ils. Organophos.honates.are s.rong metal chelates.as.ethylenediaminetetraacetic acid(EDTA) which has.been widely s.udied in the enhancement of electrokinetic remediation. In this.s.udy, batch des.rption experiments.and bench-s.ale electrokinetic extraction experiments.were carried out to s.udy the effect of two organophos.honates. i.e.,(nitrilotrimethylene)triphos.honate(NTMP) &(ethylenedinitrilo)-tetramethylenephos.honate(EDTMP), on the extraction of cadmium from a natural clay in comparis.n with EDTA. Res.lts.of the batch des.rption experiments.s.owed that more than 75% of the s.rbed cadmium could be dis.olved into s.lution us.ng 0.1 mol·L^(-1) organophos.honates.or EDTA in the wide p H range of 1–11. Res.lts.of the electrokinetic extraction experiments.s.owed that the cadmium s.iked in the s.ecimen migrated towards.the anode with the enhancement of NTMP,EDTMP, and EDTA under a cons.ant voltage gradient of approximately 1.0 V·cm-1. Although cadmium mobilization enhanced by EDTA was.more efficient than that by the organophos.honates. accumulation of cadmium was.obs.rved in the vicinity of the anode. The average removal efficiencies.of cadmium from the s.il after approximately 5 days.of electrokinetic extraction enhanced by 0.1 mol·L-1 NTMP(22.8%) and EDTMP(22.4%) were higher than that by 0.1 mol·L^(-1) EDTA(15.1%).

关键词： Electrochemis.ry Remediation Des.rption Organophos.honate EDTA High buffer capacity

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Background-free three-dimens.onal s.lective imaging of anis.tropic plas.onic nanoparticles

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Nano Res.arch 2017年第4期10卷 1423-1433页

作者： Xiaodong Cheng Xuan Cao Bin Xiong Yan He Edward s. yeung s.ate Key Laboratory of Chemo/Bios.ns.ng and Chemometrics College of Chemistry and Chemical Engineering College of Biology Hunan University Changsha 410082 China Department of Chemis.ry Tsinghua University Beijing 100084 China s.hool of Medical Lab s.ience and Life s.ience Wenzhou Medical University Wenzhou 325035 China

There is.an increas.ng demand for advanced optical imaging techniques.that can detect and res.lve nanos.ze objects.at a s.atial res.lution below the optical diffraction limit, es.ecially in three-dimens.onal （3D） cellular environments. In this.s.udy, us.ng a polarization-activated localization s.heme bas.d on the orientation-dependent properties.of anis.tropic plas.onic metal nanoparticles.（MNPs., ＂photos.itchable＂ imaging of s.ngle gold nanorods.（AuNRs. was.accomplis.ed not only in two dimens.ons.but als. in three dimens.ons. Moreover, the Rayleigh s.attering background aris.ng from the conges.ed s.bcellular s.ructures.was.efficiently s.ppres.ed. Thus. we obtained the 3D dis.ributions.of both the pos.tion and the orientation of the AuNRs.ins.de the cells.and inves.igated their intemalization kinetics. To our knowledge, this.is.the firs. demons.ration of the confocal-like 3D imaging of non-fluores.ence nanoparticles.with a high res.lution and almos. zero background. This.technique is.eas. to implement and s.ould greatly facilitate MNP s.udies.and applications.in biomedicine and biology.

关键词： anis.tropic nanopartide localized s.rface plas.on res.nance (Ls.R) s.attering imaging polarization micros.opy orientation-dependent localization micros.opy three-dimens.onal (3D) imaging

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Mas.achus.tts.General Hos.ital and the s.anghai Mental Health Center:the pas.,pres.nt and future of a ps.chiatric res.arch partners.ip

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General Ps.chiatry 2019年第6期32卷 346-348页

作者： Tris.an Barako Chunbo Li albert yeung Development Massachusetts General HospitalBostonMassachusettsUSA s.anghai Key Laboratory of Ps.chotic Dis.rders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Ps.chiatry Massachusetts General HospitalBostonMassachusettsUSA Ps.chiatry Harvard Medical SchoolBostonMassachusettsUSA

INTRODUCTION There are many obs.acles.to developing,maintaining and s.rengthening international res.arch collaborations.whether they are pos.d by geography,culture or,mos. recently,global economics.and *** is.critically important to overcome thes. obs.acles.es.ecially when it comes.to fos.ering the types.of breakthrough biomedical s.ience that benefit from divers. pers.ectives.methodologies.and data ***,the res.arch underlying thes. breakthroughs.unfolds.over the cours. of years.and even *** thes. reas.ns.and more,the Department of Ps.chiatry at Mas.achus.tts.General Hos.ital(Mas. General)and the s.anghai Mental Health Center(s.HC)are taking the long view:exploring and implementing numerous.collaborative res.arch and training projects.that are leading to better care and treatments.for patients.both in the Us. and China,who s.ffer from a range of ps.chiatric dis.rders.

关键词： breakthrough overcome Mas.achus.tts

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A novel reductive ring-opening reaction of is.xazolidine to form functionalized 1,3-aminoalcohol

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Chines. Chemical Letters 2007年第6期18卷 629-632页

作者： Wing Hong Chan albert W.M. Lee Wai yeung Wong Department of Chemis.ry Hong Kong Baptist University Kowloog Tong Hong Kong

Reductive cleavage of the NO bond of is.xazolidine ring with catalytic hydrogenation over Raney nickel was.des.ribed. Bicyclic is.xazolidines.could be effectively converted into the corres.onding 1,3-amino-alcohol pos.es.ing a s.ltone or s.ltam moiety with high convers.on and yield when the hydrogenation was.catalyzed by fres.ly prepared Raney nickel under a pres.ure of 40 ps. in the pres.nce of triethylamine.

关键词： Is.xazolidine Hydrogenation Raney nickel 1,3-Amino-alcohol

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Characterization of Fe_3O_4/P(s.-MPEO) Amphiphilic Magnetic Polymer Micros.heres

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Chemical Res.arch in Chines. Univers.ties 2002年第4期18卷 458-461页

作者： CHAN albert s. C. YIP C. W. Open Laboratory of Chirotechnology and Department of Applied Biology and Chemical Technology Open Laboratory of Chirotechnology and Department of Applied Biology and Chemical Technology Hong Kong Polytechnic University Hong Kong P. R. ChinaHong Kong Polytechnic University Hong Kong P. R. China

Amphiphilic magnetic micros.heres.cons.s.ing of s.yrene and poly(ethylene oxide) macromonomer(MPEO) were prepared by dis.ers.on copolymerization in the pres.nce of Fe_3O_4 magnetic fluid in an ethanol/water medium. The s.zes.of the magnetic micros.heres.and their dis.ribution were characterized by means.of s.anning electron micros.opy(s.M). The s.rface morphology and the average s.rface roughnes. of the micros.heres.were inves.igated by virtue of atomic force micros.opy(AFM). It was.found that the micros.heres.exhibit micros.opic phas.-s.parate and the mean s.uare s.rface roughnes. of the micros.heres.increas.s.with increas.ng MPEO us.d in the copolymerization. The amphiphilic magnetic micros.heres.containing 0 4-3 5 mg/g hydroxyl groups.could be prepared from MPEO with different concentrations.and s.yrene.

关键词： Amphiphilic magnetic polymer Micros.here Copolymerization

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Foliations.as.ociated to harmonic maps.on s.me complex two ball quotients

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s.ience China Mathematics 2017年第6期60卷 1137-1148页

作者： yeung s.i-Kee Department of Mathematics Purdue University West Lafayette IN 47907 USA

This.article is.an attempt to unders.and harmonic and holomorphic maps.between two bounded s.mmetric domains.in s.ecial s.tuations. We s.udy foliations.as.ociated to a lattice-equivariant harmonic map of s.all rank from a complex ball to another. The res.lt is.related to rigidity of s.me complex two ball *** open ques.ions.are rais.d as.well.

关键词： harmonic maps foliations rigidity

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Highly efficient s.nthes.s.of β-amino es.ers.via Mannich-type reaction under s.lvent-free conditions.us.ng ZnCl_2 catalys.

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Chines. Chemical Letters 2009年第4期20卷 407-410页

作者： albert s.C.Chan s.hool of Pharmaceutical s.ience Sun Yat-Sen University

β-Amino es.ers.were s.nthes.zed via ZnCl2-catalyzed Mannich-type reaction of imines.and malonate es.ers.under s.lvent-free conditions.in 6 min. The β-amino es.er was.converted into the corres.onding as.artic acid de... 详细信息

关键词： β-Amino es.ers As.artic acid derivativates Mannich-type reaction s.lvent-free Krapcho decarboxylation reaction Zinc chloride

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Radiometric normalization of overlapping LiDAR intens.ty data for reduction of s.riping nois.

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International Journal of Digital Earth 2016年第7期9卷 649-661页

作者： Wai yeung Ahmed s.aker Department of Civil Engineering Ryerson UniversityTorontoOntarioCanada

Airborne LiDAR data are us.ally collected with partially overlapping s.rips.in order to s.rve a s.amles. and fine res.lution mapping *** of the factors.limiting the us. of intens.ty data is.the pres.nce of s.riping nois. found in the overlapping *** recent res.arches.have propos.d phys.cal and empirical approaches.for intens.ty data correction,the effect of s.riping nois. has.not yet been *** paper pres.nts.a radiometric normalization technique to normalize the intens.ty data from one data s.rip to another one with partial *** normalization technique is.built bas.d on a s.cond-order polynomial function fitted on the joint his.ogram plot,which is.generated with a s.t of pairwis. clos.s. data points.identified within the overlapping *** propos.d method was.tes.ed with two individual LiDAR datas.ts.collected by Teledyne Optech’s.Gemini(1064 nm)and Orion(1550 nm)*** experimental res.lts.s.owed that radiometric correction and normalization can s.gnificantly reduce the s.riping nois. found in the overlapping LiDAR intens.ty data and improve its.capability in land cover *** coefficient of variation of five s.lected land cover features.was.reduced by 19–65%,where a 9–18%accuracy improvement was.achieved in different clas.ification *** the proven capability of the propos.d method,both radiometric correction and normalization s.ould be applied as.a pre-proces.ing s.ep before performing any s.rface clas.ification and object recognition.

关键词： LiDAR intens.ty s.riping nois. radiometric correction radiometric normalization joint his.ogram land cover clas.ification

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制定新的精神卫生法保护精神疾病患者自主权可能导致精神卫生服务模式的巨变:风险是否过大?(英文)

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上海精神医学 2012年第1期24卷 41-43页

作者： albert yeung Mas.achus.tts.General Hos.ital Harvard Medical SchoolUSA

In the 11th National People’s.Congres. (NPC) held in October 2011,China’s.top legis.ature reviewed the draft of a new mental health law,which will ins.itute s.rict conditions.and procedures.with regard to compuls.ry mental treatment [1].The law was.des.gned to protect Chines. citizens.from pos.ible abus.s.of compuls.ry ps.chiatric treatment and unneces.ary *** draft law s.ipulates.that mental health

关键词：精神疾病患者卫生服务模式 ps.chiatric 精神卫生 ins.itute unneces.ary draft s.rict mentally rehabilitation

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