检索结果-南通市图书馆

Re-evaluation of the phylogenetic position of the genus Dexiotrichides (Protozoa, Ciliophora, Scuticociliatida) inferred from stomatogenetic and molecular information for Dexiotrichides pangi

引用

Progress in Natural Science:Materials International 2005年第8期15卷 700-707页

作者： alan warren,david roberts,norbert wilbert London SW7 5BD UK Zoologisches Institut Universitt Bonn 53115 Bonn Germany Department of Zoology Natural History of Museum Cromwell Road London SW7 5BD UK Department of Zoology Natural History of Museum Cromwell Road

The divisional process and systematic position of the marine scuticociliate Dexiotrichides pangi are studied. Based on both stomatogenetic data and 18S rDNA gene sequences, the phylogeny and morphogenetic characteristics of this taxon, and of other related genera, are analyzed and discussed. Both the divisionary events and the molecular biological data indicate that this species/genus, together with certain other genera in the Dexiotricha-complex, occupies an intermediate position between the tetrahymenids and the “typical” scuticociliate, which suggests that the Dexiotricha-like taxa should be excluded from the “true” scuticociliates. As a further contribution, the process of stomatogenesis in D. pangi can be summarized as follows: (1) The oral primordia in the opisthe are formed only by the proliferation of basal bodies in the scutica field, which subsequently develop into three membranelles, while the new paroral membrane seems to be generated by the sub-anterior portion of somatic kinety 1 (the 1st postoral intercalary kinety). The latter character exhibits a mode similar to Tetrahymena. (2) In the proter the parental membranelles are retained and remain unchanged throughout the entire division process; only the old paroral membrane is disassembled and differentiated into the anlage, which then gives rise to the new paroral membrane and the scutica of the proter. The 18S rRNA gene sequence reported here is the first one for a ciliate in the Dexiotricha-complex.

关键词： marine ciliate systematic position stomatogenesis 18S rRNA gene sequences Dexiotrichides pangi.

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Periodic Addition of Glucose Suppressed Cyanobacterial Abundance in Additive Lake Water Samples during the Entire Bloom Season

引用

Journal of Water Resource and Protection 2024年第2期16卷 140-155页

作者： david Linz Ian Struewing Nathan Sienkiewicz alan david Steinman Charlyn Gwen Partridge Kyle McIntosh Joel Allen Jingrang Lu Stephen Vesper United States Environmental Protection Agency Cincinnati Ohio USA Annis Water Resources Institute Grand Valley State University Muskegon USA Oak Ridge Institute for Science and Education Oak Ridge Tennessee USA

Previously, we showed that prophylactic addition of glucose to Harsha Lake water samples could inhibit cyanobacteria growth, at least for a short period of time. The current study tested cyanobacterial control with glucose for the entire Harsha Lake bloom season. Water samples (1000 ml) were collected weekly from Harsha Lake during the algal-bloom season starting June 9 and lasting until August 24, 2022. To each of two 7-liter polypropylene containers, 500 ml of Harsha Lake water was added, and the containers were placed in a controlled environment chamber. To one container labeled “Treated,” 0.15 g of glucose was added, and nothing was added to the container labeled “Control.” After that, three 25 ml samples from each container were collected and used for 16S rRNA gene sequencing each week. Then 1000 ml of Harsha Lake water was newly collected each week, with 500 ml added to each container, along with the addition of 0.15 g glucose to the “Treated” container. Sequencing data were used to examine differences in the composition of bacterial communities between Treated and Control containers. Treatment with glucose altered the microbial communities by 1) reducing taxonomic diversity, 2) largely eliminating cyanobacterial taxa, and 3) increasing the relative abundance of subsets of non-cyanobacterial taxa (such as Proteobacteria and Actinobacteriota). These effects were observed across time despite weekly inputs derived directly from Lake water. The addition of glucose to a container receiving weekly additions of Lake water suppressed the cyanobacterial populations during the entire summer bloom season. The glucose appears to stimulate the diversity of certain bacterial taxa at the expense of the cyanobacteria.

关键词： Glucose Cyanobacteria 16S Amplicon Sequencing Microbial Community

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

补体相关蛋白在HIV/AIDS湿热内蕴证患者中的差异性表达

引用

中国艾滋病性病 2024年第6期30卷 579-583页

作者：孙雪晴王亚楠张海燕冯龙 david Y.W.Lee 苏铄涵徐立然 alan Wang 李青雅河南中医药大学中医学院郑州450000 河南中医药大学第一附属医院郑州450000 河南中医药大学医学院郑州450000 Harvard Medical School MA Boston 02115 Faculty of Medicine and Health Sciences of Auckland University New Zealand 6000

目的探讨补体系统相关因子在HIV/AIDS患者中及其与HIV/AIDS湿热内蕴证侯的表达特征。方法共纳入2023年3-5月于广西壮族自治区某地区就诊的HIV/AIDS患者(简称HIV组),其中包括HIV/AIDS湿热内蕴证患者组(简称HIVsr组)与HIV/AIDS无证可辨... 详细信息

目的探讨补体系统相关因子在HIV/AIDS患者中及其与HIV/AIDS湿热内蕴证侯的表达特征。方法共纳入2023年3-5月于广西壮族自治区某地区就诊的HIV/AIDS患者(简称HIV组),其中包括HIV/AIDS湿热内蕴证患者组(简称HIVsr组)与HIV/AIDS无证可辨患者组(简称HIVwz组)及同期在门诊进行体检的健康对照组。收集其基本信息并采集抗凝血液,应用流式细胞术检测T细胞亚群数量,酶联免疫吸附试验检测补体相关因子血浆表达水平,对数据进行统计分析。结果共纳入HIV组45例,其中包括HIVsr组30例与HIVwz组15例,与健康对照组15例。免疫指标对比中,HIVsr组与健康对照组相比TH/TS表达下降(P<0.05)。通路相关因子血浆表达水平对比中,HIV组与健康对照组相比除C3、C5aR、C5b因子外,C1q、MASP2、MBL等12个因子表达均下降(P<0.05),HIVsr组与HIVwz组相比C1q、C5aR、IL-6、TNF-α表达显著降低(P<0.05);HIVsr组因子C3aR与湿热内蕴证证候学量表积分呈负相关(r=-0.613,P<0.05),多元线性回归分析显示C3aR是量表积分的影响因素。结论补体系统中经典及凝集素通路参与HIV/AIDS患者病理过程,且HIV/AIDS湿热内蕴证患者的证候生物学基础与经典通路相关。C3aR对临床诊断HIV/AIDS湿热内蕴证患者有一定鉴别价值。

关键词：艾滋病湿热内蕴证补体证候诊断

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Controlling human platelet activation with calcium-binding nanoparticles

引用

Nano Research 2020年第10期13卷 2697-2705页

作者： david Cabrera Karen Walker Sandhya Moise Neil D.Telling alan G.S.Harper School of Pharmacy and Bioengineering Keele UniversityGuy Hilton Research CenireThormburrow DriveHartshill Stoke-on Trent ST47QBUK ?Central Electron Microscope Unit School of Life SciencesKeele UniversityNewcastle-under LIymeStaffordshireST55BGUK Department of Chemical Engineering University of BathBath BA27AYUK School of Medicine Keele UniversityNewcastle-under-LymeStaffordshireST55BGUK

Human platelets aggregate at sites of blood vessel damage in response to a rise in their cytosolic calcium *** these cytosolic calcium rises would provide a method to inhibit platelet activation and prevent the unwanted blood clots that causes heart attack and *** we have predicted that calcium accumulation within the lumen of an infolded portion of the platelet plasma membrane called the open canalicular system(OCS)is essential for maintaining this cytosolic calcium *** to its nanometer dimensions of the OCS,it has been difficult to measure or interfere with the predicted luminal calcium *** we utilise iron oxide magnetic nanoparticles coated with the known calcium chelator,citrate,to create calcium-binding *** were used to assess whether an OCS calcium store plays a role in controlling the dynamics of human platelet activation and *** demonstrate that citrate-coated nanoparticles are rapidly and selectively uptaken into the OCS of activated human platelets,where they act to buffer the accumulation of calcium *** with these calcium-binding nanoparticles reduced thrombin-evoked cytosolic calcium rises,and slowed platelet aggregation and clot retraction in human *** contrast,nanoparticles that cannot bind calcium have no *** study demonstrates that the OCS acts as a key source of calcium for maintaining cytosolic calcium rises and accelerating platelet aggregation,and that calcium-binding nanoparticles targeted to the OCS could provide an anti-platelet therapy to treat patients at risk of suffering heart attacks or strokes.

关键词： nanochelators human platelets open canalicular system calcium signaling nanoparticles

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Quantitative analysis of ruminal methanogenic microbial populations in beef cattle divergent in phenotypic residual feed intake(RFI)offered contrasting diets

引用

Journal of Animal Science and Biotechnology 2014年第4期5卷 439-447页

作者： Ciara A Carberry david A Kenny alan K Kelly Sinead M Waters Animal and Bioscience Research Department Animal and Grassland Research and Innovation CentreTeagascGrangeDunsanyCo.MeathIreland UCD School of Agriculture Food Science and Veterinary MedicineCollege of Life SciencesUniversity College DublinBelfieldDublin 4Ireland

Background：Methane（CH_4） emissions in cattle are an undesirable end product of rumen methanogenic fermentative activity as they are associated not only with negative environmental impacts but also with reduced host feed *** aim of this study was to quantify total and specific rumen microbial methanogenic populations in beef cattle divergently selected for residual feed intake（RFI） while offered（i） a low energy high forage（HF） diet followed by（ii） a high energy low forage（LF） *** fluid was collected from 14 high（H）and 14 low（L） RFI animals across both dietary *** real time PCR（qRT-PCR） analysis was conducted to quantify the abundance of total and specific rumen methanogenic *** correlation analysis was used to investigate the association between the relative abundance of methanogens and animal performance,rumen fermentation variables and diet ***：Abundance of methanogens,did not differ between RFI ***,relative abundance of total and specific methanogen species was affected（P〈 0.05） by diet type,with greater abundance observed while animals were offered the LF compared to the HF ***：These findings suggest that differences in abundance of specific rumen methanogen species may not contribute to variation in CH_4 emissions between efficient and inefficient animals,however dietary manipulation can influence the abundance of total and specific methanogen species.

关键词： Bovine qRT-PCR Residual feed intake Rumen methaongens

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The new COVID-19 poor and the neglected tropical diseases resurgence

引用

Infectious Diseases of Poverty 2021年第1期10卷 1-3页

作者： Peter J.Hotez alan Fenwick david Molyneux Department of Pediatrics Texas Children's Hospital CenterforVaccine DevelopmentNational School of Tropical MedicineBaylor College of MedicineHoustonTXUSA Department of Molecular Virology and Microbiology Texas Children's Hospital Center for Vaccine DevelopmentNational School of Tropical MedicineBaylor College of MedicineHoustonTXUSA Hagler Institute for Advaneed Study at Texas A&M University College StationTXUSA Department of Biology Baylor UniversityWacoTXUSA James A Baker III Institute of Public Policy Rice UniversityHoustonTXUSA Scowcroft Institute of International Affairs Bush School of Government and Public ServiceTexas A&M UniversityCollege StationTXUSA School of Public Health Faculty of MedicineImperial College Lon don LondonUK. Centre for Neglected Tropical Diseases Liverpool School ofTropical MedicineLiverpoolUK.

More than 100 million people are facing a return to extreme poverty because of coronavirus disease 2019(COVID-19),while new estimates suggest that three nations—India,Nigeria,and the Democratic Republic of the Congo-may suffer the greatest economic *** findings will have profound consequences in terms of our ability to control or eliminate the most widely prevalent neglected tropical diseases.

关键词： neglected tropical consequences

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

End-tidal capnometry during emergency department procedural sedation and analgesia： a randomized, controlled study

引用

World Journal of Emergency Medicine 2016年第1期7卷 13-18页

作者： Samuel G. Campbell Kirk D. Magee Peter J. Zed Patrick Froese Glenn Etsell alan LaPierre Donna warren Robert R. MacKinley Michael B. Butler George Kovacs david A. Petrie Department of Emergency Medicine and Anesthesia Dalhousie University Halifax Nova Scotia Canada Faculty of Pharmaceutical Sciences and Department of Emergency Medicine University of British Columbia Vancouver BC Canada Charles V. Keating Emergency and Trauma Centre Halifax Nova Scotia Canada Department of Emergency Medicine Anesthesia and Anatomy Dalhousie University Halifax Nova Scotia Canada

BACKGROUND:This prospective,randomized trial was undertaken to evaluate the utility of adding end-tidal capnometry(ETC)to pulse oximetry(PO)in patients undergoing procedural sedation and analgesia(PSA)in the emergency department(ED).METHODS:The patients were randomized to monitoring with or without ETC in addition to the current standard of *** endpoints included respiratory adverse events,with secondary endpoints of level of sedation,hypotension,other PSA-related adverse events and patient ***:Of 986 patients,501 were randomized to usual care and 485 to additional ETC *** this series,48%of the patients were female,with a mean age of 46 *** manipulations(71%),cardioversion(12%)and abscess incision and drainage(12%)were the most common procedures,and propofol and fentanyl were the sedative/analgesic combination used for most *** was no difference in patients experiencing de-saturation(Sa O2<90%)between the two groups;however,patients in the ETC group were more likely to require airway repositioning(12.9%vs.9.3%,P=0.003).Hypotension(SBP<100 mm Hg or<85 mm Hg if baseline<100 mm Hg)was observed in 16(3.3%)patients in the ETC group and 7(1.4%)in the control group(P=0.048).CONCLUSIONS:The addition of ETC does not appear to change any clinically significant *** found an increased incidence of the use of airway repositioning maneuvers and hypotension in cases where ETC was *** do not believe that ETC should be recommended as a standard of care for the monitoring of patients undergoing PSA.

关键词： Procedural sedation and analgesia Capnography Adverse events Emergency medicine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The challenges of developing an open source, standards-based technology stack to deliver the latest UK climate projections

引用

International Journal of Digital Earth 2012年第1期5卷 43-62页

作者： Ag Stephens Philip James david Alderson Stephen Pascoe Simon Abele alan Iwi Peter Chiu The British Atmospheric Data Centre DidcotUK School of Civil Engineering and Geosciences Newcastle UniversityNewcastle-Upon-TyneUK

To improve the understanding of local and regional effects of climate change,the UK government supported the development of new climate *** Met Office Hadley Centre produced a sophisticated set of probabilistic projections for future *** paper discusses the design and implementation of an interactive website to deliver those projections to a broad user *** interface presents complex data sets,generates on-the-fly products and schedules jobs to an offline weather generator capable of outputting gigabytes of data in response to a single request.A robust and scalable physical architecture was delivered through significant use of open source technologies and open standards.

关键词： geoinformatics digital earth climate change geospatial science geospatial data integration

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessment of neovascularization within carotid plaques in patients with ischemic stroke

引用

World Journal of Cardiology 2010年第4期2卷 89-97页

作者： wilbert S Aronow Chandra K Nair david Cosgrove Division of Cardiology New York Medical CollegeValhalla Center of Creighton University OmahaNE 68131United States Department of Imaging Sciences Imperial CollegeHammersmith Hospital

AIM:To assess neovascularization within human ca-rotid atherosclerotic soft plaques in patients with isch-emic ***:Eighty-one patients with ischemic stroke and 95 patients without stroke who had soft athero-sclerotic plaques in the internal carotid artery were *** thickest soft plaque in each patient was examined using contrast-enhanced ***-intensity curves were collected from 5 s to 3 min after contrast *** neovascularization within the plaques in the internal carotid artery was evaluated using the ACQ software built into the scanner by 2 of the experienced investigators who were blinded to the clinical history of the ***:Ischemic stroke was present in 7 of 33 patients(21%) with grade Ⅰ plaque,in 14 of 51 pa-tients(28%) with grade Ⅱ plaque,in 26 of 43 patients(61%) with grade Ⅲ plaque,and in 34 of 49 patients(69%) with grade Ⅳ plaque(P < 0.001 comparing grade Ⅳ plaque with grade I plaque and with grade Ⅱ plaque and P = 0.001 comparing grade Ⅲ plaque with grade Ⅰ plaque and with grade Ⅱ plaque).Analysis of the time intensity curves revealed that patients with ischemic stroke had a significantly higher intensity of enhancement(IE) than those without ischemic stroke(P < 0.01).The wash-in time(WT) of plaque was signifi-cantly shorter in stroke patients(P < 0.05).The sensi-tivity and specificity for IE in the plaque were 82% and 80%,respectively,and for WT were 68% and 74%,*** was no significant difference in the peak intensity or time to peak between the 2 ***:This study shows that the higher the grade of plaque enhancement,the higher the risk of ischemic *** data suggest that the presence of neovascularization is a marker for unstable plaque.

关键词： Carotid artery plaques Cerebral infarction Contrast-enhanced ultrasonography Ischemic stroke Neovascularization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Installation and operational effects of a HVDC submarine cable in a continental shelf setting: Bass Strait, Australia

引用

Journal of Ocean Engineering and Science 2016年第4期1卷 337-353页

作者： John Sherwood Scott Chidgey Peter Crockett david Gwyther Percival Ho Simon Stewart david Strong Bob Whitely alan Williams School of Life and Environmental Sciences Deakin UniversityWarrnamboolVictoria 3280Australia CEE Consulting 90 Bridge RoadRichmondVictoria 3121Australia Enesar Consulting Pty Ltd 124 Camberwell RdHawthorn EastVictoria 3123Australia DSA Consulting Suite 211620 St Kilda RoadMelbourneVictoria 3004Australia Coffey Natural Systems Pty Ltd 126 Trenerry CrescentAbbotsfordVictoria 3067Australia Marine Research CSIROHobartTasmania 7000Australia Picton Group Pty Ltd 30 Malpas DriveWallingtonVictoria 3222Australia

Despite the many submarine telecommunications and power cables laid world-wide there are fewer than ten published studies of their environmental effects in the refereed *** paper describes an investigation into the effects of laying and operating the Basslink High Voltage Direct Current(HVDC)cable and its associated metallic return cable across Bass Strait in South East *** more than 95%of its length the cable was directly laid into a wet jetted trench given the predominantly soft sediments *** remote video investigations found that within two years all visible evidence of the cable and trench was gone at over a third of the transects at six deep water sites(32-72 m deep).At other deep water transects the residual trench trapped drift material providing habitat for the generally sparsely distributed benthic *** surveys at both of the near shore sites(<15 m deep)on the northern side of the Strait also found the cable route was undetectable after a *** the southern side,where the cable traversed hard basalt rock near shore,it was encased in a protective cast iron half *** studies by divers over 3.5 years demonstrated the colonization of the hard shell by similar species occupying hard substrates elsewhere on the basalt *** field strengths associated with the operating cable were found to be within 0.8%of those predicted from theory with strength dropping rapidly with distance from the *** 20 m the field was indistinguishable from background.

关键词： High Voltage Direct Current Power cable Magnetic field Epibenthos Ecological effects Video survey

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：