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Effects of mesenchymal stem cell on dopaminergic neurons,motor and memory functions in animal models of Parkinson's disease:a systematic review and meta-analysis

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Neural Regeneration Research 2024年第7期19卷 1584-1592页

作者： Jong Mi Park masoud Rahmati Sang Chul Lee Jae Il Shin Yong Wook Kim Department and Research Institute of Rehabilitation Medicine Yonsei University College of MedicineSeoulSouth Korea Department of Physical Education and Sport Sciences Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran Department of Pediatrics Yonsei University College of MedicineSeoulSouth Korea

Parkinson’s disease is chara cterized by the loss of dopaminergic neurons in the substantia nigra pars com pacta,and although restoring striatal dopamine levels may improve symptoms,no treatment can cure or reve rse the disease *** cell therapy has a regenerative effect and is being actively studied as a candidate for the treatment of Parkinson’s *** stem cells are considered a promising option due to fewer ethical concerns,a lower risk of immune rejection,and a lower risk of *** performed a meta-analysis to evaluate the therapeutic effects of mesenchymal stem cells and their derivatives on motor function,memory,and preservation of dopamine rgic neurons in a Parkinson’s disease animal *** searched bibliographic databases(PubMed/MEDLINE,Embase,CENTRal,Scopus,and Web of Science)to identify articles and included only pee r-reviewed in vivo interve ntional animal studies published in any language through J une 28,*** study utilized the random-effect model to estimate the 95%confidence intervals(CI)of the standard mean differences(SMD)between the treatment and control *** use the systematic review center for laboratory animal expe rimentation’s risk of bias tool and the collaborative approach to meta-analysis and review of animal studies checklist for study quality assessment.A total of 33studies with data from 840 Parkinson’s disease model animals were included in the *** with mesenchymal stem cells significantly improved motor function as assessed by the amphetamine-induced rotational *** the stem cell types,the bone marrow MSCs with neurotrophic factor group showed la rgest effect size(SMD[95%CI]=-6.21[-9.50 to-2.93],P=0.0001,I^(2)=0.0%).The stem cell treatment group had significantly more tyrosine hydroxylase positive dopamine rgic neurons in the striatum([95%CI]=1.04[0.59 to 1.49],P=0.0001,I^(2)=65.1%)and substantia nigra(SMD[95%CI]=1.38[0.89 to 1.87],P=0.0001,I^(2)=75.3%),indicating a

关键词： animal animal experimentation mesenchymal stem cells models Parkinson’s disease stem cell transplantation

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Groundwater vulnerability assessment using a GIS-based DRASTIC method in the Erbil Dumpsite area (Kani Qirzhala), Central Erbil Basin, North Iraq

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Journal of Groundwater Science and Engineering 2024年第1期12卷 16-33页

作者： masoud H Hamed Rebwar N Dara Marios C Kirlas Department of Earth Sciences and Petroleum College of ScienceSalahaddin University-ErbilErbilIraq Department of Petroleum Engineering College of EngineeringKnowledge UniversityErbilIraq Department of Agriculture Faculty of AgricultureForestry and Natural EnvironmentAristotle University of Thessaloniki

Groundwater vulnerability assessment is a crucial step in the efficient management of groundwater resources,especially in areas with intensive anthropogenic activities and groundwater *** the present study,the DRASTIC method was applied using Geographic Information System(GIS)to delineate groundwater vulnerability zones in the Erbil Dumpsite area,Central Erbil Basin,North *** showed that the area was classified into four vulnerability classes:Very low(16.97%),low(27.67%),moderate(36.55%)and high(18.81%).The southern,south-eastern and northern parts of the study area exhibited the highest vulnerability potential,while the central-northern,northern and north-western regions displayed the lowest vulnerability ***,results of the single-parameter sensitivity analysis indicated that amongst the seven DRASTIC parameters,the unsaturated zone and the aquifer media were the most influencing *** conclustion,the correlation of 25 nitrate concentration values with the final vulnerability map,assessed using the Pearson correlation coefficient,yielded a satisfactory result of R=0.72.

关键词： DRASTIC Erbil Iraq Groundwater vulnerability assessment Nitrate Pollution Sensitivity analysis

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利用标准化降雨指数对伊朗法尔斯省干旱危害的GIS分析

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Journal of Resources and Ecology 2024年第2期15卷 439-447页

作者： masoudI masoud TAHERI Zahra 伊朗设拉子大学农业学院自然资源与环境工程系伊朗设拉子13131-71441 伊朗德黑兰大学自然资源学院环境科学系伊朗德黑兰31587-77871

干旱是广泛影响经济和环境的主要自然灾害之一。因此,有必要采用诸如标准化降雨指数(SPI)等指标来研究干旱的影响,以辨析决策和规划的现实条件。本研究的目的是利用SPI指数分析伊朗南部法尔斯省的干旱空间格局。本文根据法尔斯省42个站... 详细信息

干旱是广泛影响经济和环境的主要自然灾害之一。因此,有必要采用诸如标准化降雨指数(SPI)等指标来研究干旱的影响,以辨析决策和规划的现实条件。本研究的目的是利用SPI指数分析伊朗南部法尔斯省的干旱空间格局。本文根据法尔斯省42个站点的数据,对1990-2019年间的干旱灾害格局进行了评价。评价模型中使用的干旱危害标准包括:该时期的最严重干旱程度、干旱趋势和连续干旱年的最大数量,最终的干旱灾害图是通过计算干旱强度、连续性和趋势三个指标的算术平均值获得的。三个指标的灾害图和最终灾害脆弱图采用反距离加权法(IDW)插值制图,分为无、轻度、中度、重度和极重度5个危害等级。最终的干旱脆弱性图显示,在研究区南部观察到的中度灾害区域占研究区36%,比在北部和中部观察到的严重和非常严重灾害区(占研究区64%)分布范围更小。

关键词：干旱标准化降雨指数 GIS 灾害地图反距离加权法法尔斯省

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Comparative analysis of unipolar and bipolar plasma electrolytic oxidation coatings on al-Mg laminated macro composites

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Transactions of Nonferrous Metals Society of China 2024年

作者： Mohsen RASTEGARI masoud ATAPOUR Aboozar TAHERIZADEH Amin HAKIMIZAD Maryam RAHMATI Department of Materials Engineering， Isfahan University of Technology Yekta Mobaddel Pars Co.， Science and Technology Campus， Yazd University Dental Materials Research Center， Dental Research Institute， School of Dentistry， Isfahan University of Medical Sciences

al-Mg laminated macro composites （LMC） have garnered attention due to their excellent mechanical properties and low density. However， their weak corrosion resistance has limited their industrial applications. Plasma electrolytic oxidation （PEO） has been explored as a potential solution to this issue by producing hard and thick oxide coatings on the surface of al-Mg LMCs manufactured through hot extrusion bonding. In this study， PEO coatings were prepared on al-Mg LMCs using both unipolar and bipolar waveforms in an appropriate electrolyte for both aluminum and magnesium alloys. The techniques of FESEM/EDX， GIXRD， and electrochemical methods of Potentiodynamic polarization and EIS were carried out. The results revealed that the coatings produced using the bipolar waveform exhibited lower porosity and higher thickness than those produced using the unipolar one. The corrosion performance of the specimens' cut edge was investigated using electrochemical impedance spectroscopy （EIS） after 1， 8， and 12 hours of immersion in a 3.5%wt. NaCl solution. It was observed that the coating produced using the bipolar waveform demonstrated the highest corrosion resistance after 12 hours of immersion， with an estimated corrosion resistance of 41.87 kΩ.cm2， which was approximately three times higher than that of the unipolar coating. Notably， no signs of galvanic corrosion were observed in the LMC， and only minor corrosion attacks were observed on the magnesium layer in some areas.

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覆冰绝缘子直流电弧运动特性及燃弧时间的影响因素

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高电压技术 2024年第9期50卷 4222-4231页

作者：刘勇李超辛岳芃尹芳辉杜伯学 masoud Farzaneh 天津大学电气自动化与信息工程学院天津300072 清华大学深圳国际研究生院深圳518055 魁北克大学席库提米分校加拿大QC G7H2B1

为提高覆冰绝缘子闪络风险预测技术,分析了高压悬式覆冰绝缘子直流电弧运动特性及影响燃弧时间的因素。对直流覆冰闪络试验各阶段的泄漏电流和电弧动态特性进行了协同分析,深入研究了正、负直流电压下电弧动态行为差异。分析了燃弧时间... 详细信息

为提高覆冰绝缘子闪络风险预测技术,分析了高压悬式覆冰绝缘子直流电弧运动特性及影响燃弧时间的因素。对直流覆冰闪络试验各阶段的泄漏电流和电弧动态特性进行了协同分析,深入研究了正、负直流电压下电弧动态行为差异。分析了燃弧时间与电弧特征量、泄漏电流的相关性,并建立了针对燃弧时间的多元拟合模型。结果表明:泄漏电流和电弧长度的变化可有效区分电弧发展阶段,其中负直流电压下的电弧产生频繁,初始局部电弧分布密集,持续时间短。直流电弧延伸时产生的新放电路径导致接触型和非接触型2种电弧衰减方式,且不同极性电压下新放电路径的发展方向相反。此外,直流电弧持续期间的累积电荷量、长度平均值与燃弧时间显著正相关,且负直流电弧长度平均值的数据离散度与电荷累积量分布范围更低,建立的多变量拟合方程对电弧持续时间的预测精度更高。

关键词：覆冰绝缘子直流电弧运动机理泄漏电流燃弧时间

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Enhancing rock fragmentation prediction in mining operations:A hybrid GWO-RF model with SHAP interpretability

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Journal of Central South University 2024年第8期31卷 2916-2929页

作者： ZHANG Yu-lin QIU Yin-gui ARMAGHANI Danial Jahed MONJEZI masoud ZHOU Jian School of Resources and Safety Engineering Central South UniversityChangsha 410083China School of Civil and Environmental Engineering University of Technology SydneyNew South Wales 2007Australia Department of Mining Faculty of EngineeringTarbiat Modares UniversityTehran 14115-143Iran State Key Laboratory of Precision Blasting Jianghan UniversityWuhan 430056China Hubei Key Laboratory of Blasting Engineering Jianghan UniversityWuhan 430056China

In the mining industry,precise forecasting of rock fragmentation is critical for optimising blasting *** this study,we address the challenge of enhancing rock fragmentation assessment by developing a novel hybrid predictive model named *** model combines the grey wolf optimization(GWO)algorithm with the random forest(RF)technique to predict the D_(80)value,a critical parameter in evaluating rock fragmentation *** study is conducted using a dataset from Sarcheshmeh Copper Mine,employing six different swarm sizes for the GWO-RF hybrid model *** GWO-RF model’s hyperparameters are systematically optimized within established bounds,and its performance is rigorously evaluated using multiple evaluation *** results show that the GWO-RF hybrid model has higher predictive skills,exceeding traditional models in terms of ***,the interpretability of the GWO-RF model is enhanced through the utilization of SHapley Additive exPlanations(SHAP)*** insights gained from this research contribute to optimizing blasting operations and rock fragmentation outcomes in the mining industry.

关键词： blasting rock fragmentation random forest grey wolf optimization hybrid tree-based technique

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Dark Matter Density Profiles of Selected Spiral Galaxies

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International Journal of Astronomy and Astrophysics 2024年第3期14卷 172-183页

作者： alberto Sadun Brittany Salmon Conor Evans masoud Asadi-Zeydabadi Department of Physics University of Colorado Denver Denver USA

Understanding the dark matter distribution throughout a galaxy can provide insight into its elusive nature. Numerous density profiles, such as the Navarro, Frenk and White model, have been created in an attempt to study this distribution through analyzing orbital velocities of luminous matter and modeling dark matter distributions to explain these observations. However, we are interested in a simple model to consider the significant fluctuations in rotation curves at larger radii. Therefore, our model is much simpler compared to those previously mentioned. Our model used all the observational data available for four selected galactic rotation curves. These data present a significant variation in the orbital velocity of matter at the same distances. By running real observational data through our model, we show that the density of the dark matter within them shows real complex structure, which is not suggested by other computational models. Our aim of this paper is to model this structure and then speculate as to the cause and implications of these density fluctuations.

关键词： Dark Matter Density Galactic Rotation Curves Spiral Galaxies NGC 2841 NGC 4527 NGC 4945 NGC 3198

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Analysis of the COVID-19, Outbreak in Brazil Using Topological Weighted Centroid: An Intelligent Geographic Information System Approach

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Journal of Data Analysis and Information Processing 2024年第2期12卷 248-266页

作者： masoud Asadi-Zeydabadi Marina Mizukoshi Massimo Buscema Giulia Massini Weldon Lodwick Department of Physics University of Colorado Denver Colorado USA Institute of Mathematics and Statistics Federal University of Goi&#225s Goiania Goi&#225s Brazil Semeion Research Center Rome Italy Department of Mathematical and Statistical Sciences University of Colorado Denver Colorado USA

This study used Topological Weighted Centroid (TWC) to analyze the Coronavirus outbreak in Brazil. This analysis only uses latitude and longitude in formation of the capitals with the confirmed cases on May 24, 2020 to illustrate the usefulness of TWC though any date could have been used. There are three types of TWC analyses, each type having five associated algorithms that produce fifteen maps, TWC-Original, TWC-Frequency and TWC-Windowing. We focus on TWC-Original to illustrate our approach. The TWC method without using the transportation information predicts the network for COVID-19 outbreak that matches very well with the main radial transportation routes network in Brazil.

关键词： COVID-19 Topological Weighted Centroid (TWC) algorithms TWC-Original TWC-Frequency and TWC-Windowing

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Effect of self-modeling and self-controlled feedback on the performance of professional swimmers and waterpolo players

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Sports Medicine and Health Science 2024年第2期6卷 167-172页

作者： masoud Mirmoezzi Mansour Sayyah Morteza Taheri Khadijeh Irandoust Mandana Sangari Fatemeh Mirakhori ali Seghatoleslami Lee Hill Katja Weiss Beat Knechtle Amine Ghram Faculty of Physical Education and Sport Science Islamic Azad UniversityTehranIran Kashan University of Medical Sciences KashanIran Department of Behavioral and Cognitive saciences in Sport University of TehranTehranIran Islamic Azad University Chalous BranchMazandaranIran University of Birjand BirjandIran Division of Gastroenterology&Nutrition Department of PediatricsMcMaster UniversityHamiltonCanada Medbase St.Gallen Am Vadianplatz St.GallenSwitzerland Institute of Primary Care University of ZurichZurichSwitzerland Cardiac Rehabilitation Department Heart HospitalHamad Medical CorporationDohaQatar Healthy Living for Pandemic Event Protection(HL-PIVOT)Network ChicagoIllUSA Department of Sport Sciences Imam Khomeini International UniversityQazvinIran

Self-modeling(SM)and self-control(SC)feedback can be presented as two solutions for learning ***,the aim of the present study was to investigate the effects of SM and SC feedback on 100-m freestyle performance of professional swimmers and waterpolo players.25 elite male swimmers and waterpolo players,were randomly assigned to four groups:swimmer group with SM,swimmer group with SM and SC feedback,waterpolo players group with SM,and waterpolo players group with SM and SC feedback.100-m freestyle times and performance were *** and SC feedback for the participants were utilized at the acquisition *** device used included a Lenovo B570 laptop and an Exilim ZR200 canon *** and SC feedback presented to the swimmers and waterpolo players led to improved speed and results,and the effect of presenting SM with SC feedback to swimmers had better *** conclusion,the present study indicates that SC modeling of watching video is a suitable method for professional *** polo trainers can also use SM and SC feedback to enhance their players'swimming technique.

关键词： Feedback Self-control Self-modeling Swimming Water polo

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白内障手术候选者的眼部生物特征参数分析

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国际眼科杂志 2024年第8期24卷 1186-1193页

作者： Zahra Sarlak masoud Khorrami-Nejad Hamed Ghasemi ali Nouraeinejad Reza Yousefi 伊朗德黑兰医科大学Farabi眼科医院转化眼科研究中心 *** 伊朗德黑兰医科大学康复学院视光系 ***

目的:分析白内障手术候选人的眼部生物特征参数。方法:横断面研究。纳入2017-01/2021-09就诊于伊朗德黑兰Farabi眼科医院的4607例白内障患者(4607眼)。使用IOLMaster 700评估眼轴(al)、角膜曲率(Kf、Ks、Km)、前房深度(ACD)。根据al分为... 详细信息

目的:分析白内障手术候选人的眼部生物特征参数。方法:横断面研究。纳入2017-01/2021-09就诊于伊朗德黑兰Farabi眼科医院的4607例白内障患者(4607眼)。使用IOLMaster 700评估眼轴(al)、角膜曲率(Kf、Ks、Km)、前房深度(ACD)。根据al分为22 mmal、22 mm≤al≤25 mm和al>25 mm组,根据ACD分为3.00 mm3.60 mm组。结果:患者平均年龄60.3±14.1(8-95)岁,女2243例(48.69%),男2364例(51.31%)。al、ACD和平均角膜曲率范围分别为23.1-23.4 mm、3.1-3.2 mm和44.50-45.00 D。al>25 mm组ACD平均值显著高于22 mm≤al≤25 mm组和22 mmal组(P3.60 mm组的平均al显著高于3.00 mmal>25 mm组的Kf、Ks、Km均值显著高于ACD>3.60 mm组和22 mmal组(Pal长的白内障患者ACD更深,角膜更平坦;al短的患者ACD较浅,角膜较陡。此外,深ACD患者的al较长,角膜较平坦,浅ACD患者的al较低,角膜较陡。

关键词：白内障眼轴前房深度角膜曲率

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